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Dr. Chandi Charan Mandal

Radiologist, Kolkata

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Dr. Chandi Charan Mandal Radiologist, Kolkata
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I pride myself in attending local and statewide seminars to stay current with the latest techniques, and treatment planning....more
I pride myself in attending local and statewide seminars to stay current with the latest techniques, and treatment planning.
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Dr. Chandi Charan Mandal is one of the best Radiologists in Salt Lake, Kolkata. She is currently associated with Dr. Chandi Charan Mandal's clinic in Salt Lake, Kolkata. Book an appointment online with Dr. Chandi Charan Mandal and consult privately on Lybrate.com.

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Diseased Uterus - Can it be Replaced?

Health and Medical ARC Fertility
IVF Specialist, Chennai
Diseased Uterus - Can it be Replaced?

In case you have a diseased uterus, which makes you infertile, you can undergo a procedure known as uterus transplant or uterine transplant to get pregnant. In the process of sexual reproduction, a diseased uterus does not allow embryonic implantation. This factor is referred to as uterine factor infertility or UFI. As a result, you will not be able to get pregnant. Learn more about having healthy pregnancy.

Who requires a uterus transplant?
This procedure involves women who have UFI and women who had their uterus removed by hysterectomy. Women who have a damaged uterus on account of an injury or infection, which does not function anymore, can also undergo a uterus transplant procedure. Women from the age of 21 to 45 are eligible for this procedure. Many women are born without having a uterus. This condition is called Mayer-Rokitansky-Küster-Hauser syndrome.

Procedure
Uterus transplantation begins with undertaking a uterus retrieval surgery on the uterus donor. The uterus, which is recovered has to be stored and transported to the location of the patient undergoing the transplant. An ischemic tolerance may last over 24 hours. Three major surgeries have to be carried out with the recipient. Firstly, a transplantation surgery is required in which the donor’s uterus gets transplanted. In case pregnancy develops, a caesarean section surgery has to be performed. The patient is given immune suppressive therapy. After childbirth, a hysterectomy is done in order to terminate the immune suppressive therapy.

Will the women be able to get pregnant after having sex?
Women receiving a uterus transplant will not be capable of becoming pregnant without undergoing fertility treatments. The transplanted uterus is not connected with the fallopian tubes, which is the location of the normal fertilisation process. The women will require to carry out IVF or in vitro fertilisation to become pregnant after a uterus transplant. IVF is a process in which the eggs are removed from the ovaries and get fertilised in a laboratory. Then, they are implanted in the uterus. After undergoing the uterus transplant procedure, a woman has to wait for a period of one year. The uterus requires time for healing and after recovery, the embryo may be implanted for pregnancy. After giving birth successfully, a woman will be able to keep the transplanted uterus. This is a reason why IVF is a popular procedure.

She has the option to get pregnant again. However, after giving birth twice, a hysterectomy must be carried out for the removal of the uterus. This is done so that the woman can stop using the immune suppressant drugs, which are associated with major risks. Uterus transplant is a relatively new technology. In October 2014, the first healthy baby was born to a woman who had undergone a uterus transplant. This surgery is kind of experimental in nature and is usually the last option for getting pregnant.

3818 people found this helpful

My age is 28 and I am suffering from back pain due to L3, L4, L5 Disc bulging. Kindly suggest me a solution to over come from back pain without surgery.

Diploma In Orthopaedics (D. Ortho)
Orthopedist, Amravati
My age is 28 and I am suffering from back pain due to L3, L4, L5 Disc bulging. Kindly suggest me a solution to over c...
Hello, Medication like methylcobalamine with muscle relaxant and analgesic will reduce pain; you can take them . I will advise to check your vit B12 and vit D3 level. Hope this answers your query. If you have additional questions or follow up queries then please do not hesitate in writing to us. I will be happy to answer your queries.
1 person found this helpful
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Breast Cancer - Risk Factors Associated With It!

MS - General Surgery, MCH - Oncology , MBBS
Oncologist, Pune
Breast Cancer - Risk Factors Associated With It!

Detecting a lump on your breasts can be stressful for any women. Breast cancer is a common type of cancer and is said to affect primarily affect women though 1% of breast cancer cases affect men. Breast cancer can be categorized into different types based on their capability to affect surrounding tissues.

The most common amongst these are:

  • Ductal carcinoma in situ
  • Invasive ductal carcinoma
  • Invasive lobular carcinoma

Breast cancer is caused by mutations of a person’s DNA cells. This could be inherited from one’s parents or acquired by an unhealthy lifestyle. These DNA mutations cause cells in the breast tissue to multiply rapidly and turn cancerous. The risk factors for breast cancer can be categorized as modifiable and non-modifiable.

Modifiable risk factors:

Non-modifiable risk factors:

  • Age
  • Family Medical History
  • Personal Medical History
  • Atypical hyperplasia
  • Early start of menstruation cycle
  • Presence of dense breast tissue
  • Inherited genetic mutations

As with any other type of cancer, the earlier it is diagnosed, the easier it is to treat. In its early stages, breast cancer is not painful and has negligible symptoms. In most cases, it is detected only by finding a lump on the breast or through a mammography. This lump may also be present in the armpit or above the collar bone. Some of the other symptoms of breast cancer include:

  • Nipple inversion
  • Discharge from the nipples
  • Changes in the colour and texture of skin covering the breast

Breast cancer has five stages beginning from 0 and going up to 4. This is based on the size of the tumour, involvement of lymph nodes and whether or not metastasis has occurred.

  • Stage 0: At this stage, the tumour does not affect the lymph nodes and has not metastasized. Thus at this stage, it is noninvasive.
  • Stage I:  In this case the tumour is smaller than 2 cm in diameter and has not spread to any of the surrounding tissues.
  • Stage II: In this stage, the cancerous tumours are still fairly small in size but also affect the surrounding lymph nodes.
  • Stage III: These tumours are larger than 5 cm in diameter and involve the lymph nodes to a greater extent.
  • Stage IV: This is also known as metastatic breast cancer. In this stage, the cancer cells metastasize to other parts of the body.

Surgery is the most preferred form of treatment for breast cancer. This may be combined with radiation, chemotherapy, targeted therapy or hormone therapy depending on the stage and type of cancer, the patient's overall health, age and personal preferences. In case you have a concern or query you can always consult an expert & get answers to your questions!

1985 people found this helpful

5 Super Brain Drinks That Boost Your Memory

M.Sc. in Dietetics and Food Service Management , Post Graduate Diploma In Computer Application, P.G.Diploma in Clinical Nutrition & Dietetics , B.Sc.Clinical Nutrition & Dietetics
Dietitian/Nutritionist, Mumbai
5 Super Brain Drinks That Boost Your Memory

Beet juice: apart from being a nutritional powerhouse, beet juice is a great source of nitric acid. The latter helps with blood flow in the body. A smooth blood flow, on the other hand, helps the brain in functioning properly. A study has found that people who consume beet juice have an increased circulation in the white matter resulting from an increased brain activity. This juice is sweet in taste and can be consumed every alternate day.

Berry smoothies: acai is a fruit which has a south african origin and hits the top of the list when it comes to brain assisting food. It increases the flow of the blood and dilates the blood vessels. However, this is extremely expensive. Berries also have a similar effect on the brain, but they are less powerful in nature. What can be done is to mix a little ingredient of acai in frozen berries juice and drink the same every day. Frozen berries retain the freshness and the nutritional benefits. This drink will improvise your brain and increase blood flow in the body.

Pomegranate juice: pomegranate is a great antioxidant and it very aptly limits the free radicals from damaging the brain cells. Antioxidants are also credited with increased blood flow and protection of the heart. A healthy cardiovascular system is synonymous to an increased brain function. What is surprising is the fact that pomegranate has more antioxidant content compared to red wine and green tea. Pomegranate juice can be consumed daily during the morning or afternoon.

Carrot juice: carrot is known for its healthy components that are beneficial for the eyes. Recent studies have revealed that they are great for the brain too. Like other colored vegetables, they are a great source of antioxidant and have a high content of beta-carotene. Carrot juice can reduce the inflammation of the brain cells and improve memory. Carrot juice is not at all bitter and the same can be consumed every alternate day after your meal.

Cocoa: a harvard study revealed that two cups of cocoa on a daily basis greatly helps a person in improving memory. Cocoa contains flavanols that keep the blood pressure normal and relaxes the blood vessel linings. Cocoa is also known to be a great antioxidant agent that limits the free radical to affect the brain cells. Cocoa should not be overloaded with sugar and should be consumed hot before starting your day.

44 people found this helpful

Hello Dr. Sir, I am Harvinder singh from yamunanagar, Haryana. I have lower back pain since last 2 years. Its slip disc and sciatica pain in left leg. I am very unhappy with this problem. Please advice me best of best treatment for the same and where I can get the same.

BAMS
Ayurveda,
Hello Dr. Sir, I am Harvinder singh from yamunanagar, Haryana. I have lower back pain since last 2 years. Its slip di...
You may use yogi joint pain churna for few days, if its helpful for you, then continue to get relief from sciatica.
1 person found this helpful
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Breast Cancer Awareness

BHMS, Certified in Aesthetic Skin Treatments, Certified in Applied Behaviour Analysis
Homeopath, Mumbai
Breast Cancer Awareness

Breast cancer awareness

October is breast cancer awareness month and a great time to highlight the importance of maintaining healthy habits to support breast health. One disease that most women fear these days, you would probably reply" breast cancer.

Understand what you can do to reduce your breast cancer risk. So follow these guidelines and know that you are doing all that you possibly can to protect yourself from developing breast cancer. Be thankful every day that your breasts are healthy. 

Check your own breasts regularly. Do monthly self-breast examinations after your period is over. If you find any lumps or tenderness that concerns you, have it checked out right away. Fortunately, 80% of breast lumps are benign. When you examine your breasts, remember that lumps which are soft, movable, and change with your menstrual cycle are much less likely to be cancerous. Any discharge from the nipple other than breast milk should be checked out by your health professional.
Get regular mammograms. In a woman without breast symptoms and with no significant risk of breast cancer, I recommend mammograms beginning age 35 or 40 every two years. For women without breast symptoms who are at higher risk of breast cancer, I recommend yearly mammograms beginning at age 35. Beginning at age 50, the rate of breast cancer goes up, so yearly mammograms are advised.

Limit alcohol intake. The more alcohol you drink, the greater your risk of developing breast cancer.

Get to and maintain a healthy weight - if your bmi is out of the healthy range, find a program and tools to help you get to a healthy weight, which is important for maintaining health in general, including breast health. Obesity, particularly after menopause, can greatly increase your risk of breast cancer. Aim for gradual weight loss by choosing minimally processed foods and eating smaller portions.

Don't smoke - accumulating evidence suggests a link between smoking and breast cancer risk, particularly in pre -menopausal women.

Exercise regularly - physical activity can help you maintain a healthy weight, which, in turn, helps prevent breast cancer. 

Limit dose and duration of hormone therapy - if you're taking hormone therapy for menopausal symptoms, ask your doctor about other options. You might be able to manage your symptoms with non-hormonal therapies and medications.

Choose the right supplements - filling in nutrition gaps with supplements can help you support breast health. Look for options that contain vitamin d and omega-3 fatty acids, as they have both been associated with maintaining breast health.

Breast-feed your babies for as long as possible - women who breast-feed their babies for at least a year in total have a reduced risk of developing breast cancer later.

2 people found this helpful

Know More About Meningitis!

Fellowship in Neonatology, MRCPCH(UK), Diploma in Child Health (DCH), MBBS
Pediatrician, Delhi
Know More About Meningitis!

Arguably one of the most fatal diseases that threaten human life, Meningitis has been the cause of a lot of recent deaths. Essentially Meningitis is triggered off by the anomalous inflammation of the protective membranes called meninges in the brain and spinal cord. Spurred by some sort of a bacterial or viral attack, this condition emanates from an infection of the fluids in the cranial chamber. Often such conditions are also stimulated by some external injury, cancerous development or even certain kinds of reaction from a given drug or the other. 

Depending on the precise cause of the disease, Meningitis may be categorized as Bacterial Meningitis, Viral Meningitis or Fungal Meningitis. Other forms of Meningitis include parasitic Meningitis, Amebic Meningitis and Non-Infectious Meningitis. Meningitis could potentially be contagious. Through lengthy and proximal contact like coughing or kissing, if saliva or spit gets exchanged, Meningitis causing germs may spread from one person to the other.

Bacterial Meningitis
Streptococcus pneumoniae and Neisseria Meningitidis are the two of the most rampant Meningitis causing bacteria. They have the potential of causing irreversible damage to several vital organs. However, with substantive progress in medical science, effective and suitable medication has been made available to the larger populace. But, immediate attention is imperative in this case.

Viral Meningitis
Viral Meningitis is relatively milder than the other forms of meningitis. Enteroviruses, arboviruses and herpes virus are some of the most common sources of this kind of Meningitis. People with strong immunity are usually able to overcome this without much ado. Vaccines are available widely in the markets to cure viral meningitis.

Fungal Meningitis
Fungal Meningitis are caused primarily from external influences. Inhaling fungal spores from the environment is one of the most prominent factors that lead to Meningitis. People suffering from fatal diseases like cancer, diabetes or HIV are more susceptible to fungal Meningitis. While these are a few of the primary forms of meningitis, other triggers to this disease occur due to various environmental interventions. These are consequent upon interactions with various disease causing allergens. Cure to meningitis is available in the form of intravenous injections. But timely diagnosis and treatment is essential for a good outcome. If you wish to discuss about any specific problem, you can consult a pediatrician.

4482 people found this helpful

Uterine Fibroid - How Removing Them Will Help You?

MD - Obstetrtics & Gynaecology, MBBS, Diploma in Specialised Advanced Gynaecological Endoscopy
Gynaecologist, Delhi
Uterine Fibroid - How Removing Them Will Help You?

It is very common for women to have heavy and painful periods or have a feeling of fullness in the lower abdomen. Although, it may not sound very alarming these could be the symptoms of uterine fibroids. These are the most common types of benign tumours found in women. The fibroids are basically some tissues and muscle cells that grow within the uterus, outside the uterus, or along the wall of the uterus. The fibroids are usually benign and asymptomatic and do not require any treatment unless they cause problems. 

Know the causes 

Though the exact cause of fibroid formation is not known, it is believed that the female hormones estrogen and progesterone have a role to play in their formation. Fibroids are formed only when a woman is producing these hormones and they are not seen in women in non-reproductive age i.e. before starting of menses or after stoppage of menses (menopause). If fibroids are persisting even after menopause or especially if increasing in size then it is an alarming sign. Such a fibroid needs to be taken care of immediately. 

What are the symptoms? 

Fibroids often remain quiet for long periods of time. They cause nonspecific symptoms in the pelvis and abdomen including: 

  1. Fullness in the abdomen 
  2. Low back pain 
  3. Irregular menstruation 
  4. Cramping with menstruation 
  5. Painful sex 
  6. Increased urgency to urinate 
  7. Anemia, leading to tiredness and weakness 
  8. Infertility Diagnosing the fibroids 

When these symptoms are recurrent, it is good to confirm the diagnosis. This can happen with a pelvic exam followed by ultrasound scanning to confirm the size and location of the fibroids. A blood test also may be done to confirm anemia, which is common due to heavy periods.

Treatment Options 

Management of fibroids can range from doing nothing to periodic monitoring to surgical removal. 

  1. If pain and heavy bleeding are the only symptoms, then pain killers like ibuprofen should suffice for symptomatic relief. Anemia, if severe, may require iron supplementation. 
  2. Embolization is an option which shrinks the fibroid, at the same time preserving the uterus. The blood flow to the fibroid is cut off, thereby preventing its further growth. It takes about 1 to 3 hours and requires some bed rest after the procedure. There could be some pelvic pain and vaginal bleeding, which will gradually subside. The fibroids may grow back, but the benefits of keeping the uterus are definitely there. This is suitable in case of single fibroid with specific blood supply. 
  3. The next surgical option is myomectomy, where the portion of the uterus which contains the fibroid alone is removed. This is done in women who still wish to get pregnant and in women who would like to retain the uterus. This can also be achieved laparoscopically( key hole surgery). In such cases, fibroids are cut into small pieces and then removed from the body. This procedure should be done by a doctor specialised in advanced gynecological endoscopy as all this cutting should be done in a bag to avoid any spillage of cells inside the abdominal cavity. This procedure is known as Laparoscopic Myomectomy with In-bag Moecellation. 
  4. In women who have crossed their pregnancy phase, hysterectomy or complete removal of the uterus is advised. In these women, the bleeding and pain may not have subsided even after years of treatment with hormones. The growing fibroids could be pressing on the adjacent organs, causing pressure. This is the only definitive treatment and should be done in women have completed their family and don’t desire to be pregnant. 
  5. Myomectomy and hysterectomy may be done laparoscopically or with an open method depending on the overall health, the size and location of the fibroids in the uterus.

In case you have a concern or query you can always consult an expert & get answers to your questions!

3960 people found this helpful

Know More About Bone Cancer!

MBBS, MS - Orthopaedics
Orthopedist, Chennai
Know More About Bone Cancer!

Cancer that originates in the bones of a human body is referred to as bone cancer. Any bone could come under the threat of this disease, but generally the longer bones of your body, so to say the bones of your limbs, are at a greater risk. 

A few factors that might push you an inch closer to bone cancer are:

  1. Genes could jinx your health: A few typical genetic syndromes could increase a person's chances of contracting bone cancer. These syndromes could have been active in any person belonging to your lineage. One such syndrome is Li-Fraumeni.
  2. Treatment for one kind of cancer can make you prone to some other kind: Radiation affects your bones adversely. A patient of breast cancer might be undergoing radiation therapy that further increases his or her risk of contracting bone cancer in future.  
  3. Paget's disease can have unfavorable implications: Paget's disease is a disease that affects elderly people. This condition, if left untreated, can turn into bone cancer at a later stage. 

Several symptoms of bone cancer can be found below:

  1. Sudden loss of weight: If you lose a considerable amount of weight in a few weeks time without having made any effort at all, you should probably be worried about the health of your bones. Bone cancer can result in sudden and unintentional weight loss. 
  2. Unexpected bone fracture or breakage: Cancer of the bones is known to gnaw at the strength of your bones. Weakened and diseased bones can break or get fractured very easily. An unexpected fracture should not be overlooked so as to prevent chances of anything more harmful.
  3. Long spans of unyielding exhaustion: Constant fatigue and sleepiness might be hinting at a more serious underlying problem. The bones in your body hold you together; cancerous bone cells can make you feel exhausted without much exertion as your bones lose their inherent potency.
  4. Persistent pain in the bones: Excruciating cramps or pangs of stinging pain in a person's bones either continuously or at odd hours, could be indicative of bone cancer. Such instances require the advice and guidance of an experienced oncologist.
  5. Bone swelling: The area affected by bone cancer can grow big and tender or the bone itself can swell up.

In case you have a concern or query you can always consult an expert & get answers to your questions!

5498 people found this helpful

I am 63 year old male, having- (1) a sciatica on right side (2) herniation between in lumber, as a result suffering from leg and lower back pain. I want your valued answer of treatment.

Dip. SICOT (Belgium), MNAMS, DNB (Orthopedics), MBBS
Orthopedist, Delhi
Hi thanks for your query and welcome to lybrate. I am Dr. Akshay from fortis hospital, new delhi. For me to answer your question, I need some information from your side: - a detailed neurological examination including assessment of motor, sensory ex and analysis of deep tendon reflexes of lower limbs - dynamic x rays of ls spine - mri ls spine to correlate clinical findings with radiology. Do not hesitate to contact me if you need any further assistance. You can also discuss your case and treatment plans with me in a greater detail in a private consultation.
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