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I have three fully impacted wisdom teeth. But they are not infected. From last 6 months I have jaw, throat, ear, tongue & tooth pains. Meanwhile I suffered from throat infection which was due to Enterobacter clocae. I have also reactive lymphnodes in neck. Can impacted wisdom teeth cause all such symptoms?
There is a blister/ulcer on the side of newly coming wisdom tooth. I don't take any tobacco products and I am also a non alcoholic. Could it be cancer because my father was also having cancer. Please help me.
After diagnose from breast cancer what are the major n minor steps/tips/diet/exercise for a healthy life? All treatment was done at TMH mumbai. I am 26 years old.
My skin often gets red with a small swollen area and around it d skin gets red. Is it skin infection or is related to blood cancer?
What will be the process of treatment for a patient who has just overcome from the first stage of cancer?
I have detected carcino sarcoma of fallopian tube in march 2014 and it was second stage and no metastases. Undergone surgery TAH+BSO+Omentectmy and received 4 cycles of chemotherapy. Have done MRI. It shows normal and no metastases and no need of radiation. Now I have been doing followup checkup for last 4 months. USG is showing normal. Now I don't have any problems. Is there any chance to recurrence this disease? What are the necessary precautions should be taken? Any significants to do PET scan?
Sir my son has diagnosis osteosarcoma a bone cancer ,and I want to know about the role of biopsy in treatment of osteosarcoma.
Hi doctor my mom went for breast surgery in Pondy. Before surgery he went 3 chemo to reduce tumor size. Then we came back to home town Tuticorin .Now the cell spread to liver. So present situation she cannot take food very weak can’t take chemo and oral tablet. Can you help me in this case for second opinion My Sister take care my mom. I am in Singapore Please help for opinion thanks.
Sildenafil (Viagra), whose function is to inhibit a substance called Phosphodiestarase-5 or PDE5 - was initially used only for the treatment of angina pectoris (a cardiovascular problem) and pulmonary hypertension. Incidentally, it was discovered that it could help the issue of erectile dysfunction too, and thus became hugely popular in the late 1990s. The little blue pill, as it was called, ruled more than 50% of the sexual dysfunction market for more than 15 years. However, as its popularity and usage increased, so did the scientific information about this drug, and now there is an increased speculation that it could be contributing to skin cancer, specifically melanoma. This is considered as one of the most dangerous forms of skin cancer and so the safety of Viagra sildenafil came into question.
Research has shown that users of Viagra sildenafil are at a higher risk for developing melanoma. There are reports stating that about 45 million men are at an increased risk of developing melanoma due to associated Viagra sildenafil use. The risk of developing melanoma was found to increase in men using ED drugs by 21%. Though there is no conclusive proof as yet that sildenafil is the cause, research is increasingly pointing out its role in melanoma. For example, PDE5 inhibitors (sildenafil, tadalafil, vardenafil) are known to promote melanin synthesis, which may exacerbate melanoma development.
The analysis of biochemical pathways of this correlation suggests that Viagra sildenafil triggers a special biochemical action involving the growth-stimulating cGMP (cyclic guanosine monophosphate (an intracellular signaling molecule) which in turn promotes the growth of malignant melanoma. In normal cases, the enzyme phosphodiesterase type 5 (PDE5) regulates the cGMP preventing any adverse cellular activity. Sildenafil inhibits the production of this enzyme, and potentiates a specific cGMP-related biochemical mechanism (called cGMP-cGKI pathway) , and thereby contributes to malignant melanoma. This has been proven to happen in mice and is yet to be proven in humans.
However, there are also reports which suggest that this does not happen due to Viagra sildenafil per se, but due to greater exposure to sun, which even otherwise increases the chances of skin cancer in general, and melanoma in particular. The countering theories also say that the population in which skin cancer was detected, comprised mostly of high income individuals who spent a significant amount of time holidaying on beaches and are not connected to the extensive use of Viagra per se.
Therefore, though there is a correlation that has been established, there is no definite proof that Viagra sildenafil causes skin cancer. It is however, advisable to use ED drugs after medical consultation. If a patient has a genetic predisposition to develop melanoma, it is advisable to seek medical advice before the use of ED drugs. Occasional use should not be harmful. Also, when going out in the sun, limiting exposure to direct sun and UV protection should be managed too.