Dr. Susmita Mukherjee

Medical science constantly challenges the boundaries by finding not only the cures to the most dangerous diseases, but finds a way to prevent them even before they occur. With years of research, practice and data available for analysis, scientists are using advanced technology in combination with years of research to create a predicting mechanism for often fatal diseases like cancer.

Breast cancer screening has always been done with mammography. The fact is that this method is only 75% accurate, laden with false positives and misses a whole set of women totally- and that too when cancer has already developed. Part of the problem comes from the dense breast tissue which one in three women have. This tissue masks the lumps, which makes it difficult for mammograms to accurately screen cancer.

Some breakthrough scientific methods are changing this by drawing on years of research to predict this deadly disease, years before it can manifest itself.

A genetic test to predict cancer 10-11 years ahead of time

This test was performed to see how environmental factors could influence cancer, along with habits like smoking, abusing alcohol or hormones, genetic changes that occur and are put a large percentage of the women at a high risk of developing this disease.

A simple blood test is used for the genetic analysis of hereditary cancer. Researchers found a biological marker, methylation of the ATM gene, which has a very high ability to predict the risk of developing cancer, several years before diagnosis. 'Methylation' concluded that when one biological indicator is exposed to carcinogenic substances, or other abusive substances like tobacco and alcohol, it may trigger the development of cancer.  On the flip side, this test will take time to reach the commercial market and even then cannot give an exact timeline as to when someone may develop the disease.

A simple blood test to predict breast cancer 5 years before it develops

This is the kind of medical miracle the world is looking for. Last year in April, researches in Denmark identified a simple blood test that can predict breast cancer five years before it actually develops with an accuracy of a whopping 80%.

It works by "measuring all of the compounds in the blood to build a 'metabolic profile' of an individual, in order to detect changes in the way chemicals are processed, during a pre-cancerous stage," says Laura Donnelly, health editor at The Telegraph, which covered this development. Danish researchers observed 57,000 participants over 20 years, gathering blood samples along the way, specifically comparing a set of 800 women who remained healthy or developed breast cancer within 7 years of their first blood sample. The researchers found they were able to predict, with 80 percent accuracy, which patients would be affected by the disease, just by looking at the metabolic profiles they built from the participants' blood samples. The results have been published in Metabolomics.

 

What is premenstrual syndrome (PMS)? In layman's language, it is that time of the month you don't really want to unnecessarily bother a woman or you might have to face the brunt of an emotional outburst. In medical terms, it is a combination of emotional, physical, psychological changes that occur in a woman after ovulation and culminates with the ending of her menstrual flow. The most common mood-related symptoms are irritability, depression, crying, oversensitivity, and mood swings. The most common physical symptoms are fatigue, bloating, breast tenderness, acne, and appetite changes with food cravings. In severe cases, anger, irritability, anxiety and tension leads to loss of the functioning ability of a woman. If you've been there or are suffering, you are not alone. There are scores of women around the world who experience these symptoms.

Here are ways to minimize and get rid of PMS.

1.        Control PMS with diet changes: Certain food types in general are not a healthy choice but can cause more harm than good during PMS. Depending on what factor affects you the most, cut down on these types of food.
a.        Salt: Excess salt can lead to bloating.
b.        Caffeine: Can lead to anxiety, sleeplessness and irritability
c.        Alcohol: The concoction for depression
d.        Sugar: Can cause mood swings
As always, eating more fruits veggies and grains at the right time can keep you healthy and prepared for those dreaded days.

2. Exercise: Exercise is a mood lifter. It gets you into shape, adds to your stamina and slowly but steadily boosts your confidence to become slimmer, stronger, and fitter. The trick is to pick up on an exercise you love. Hit the road and run free with your thoughts or turn on the music and dance with aerobics.

3.        Stock up on the vitamins: Hormonal imbalances are the primary cause behind PMS. Though it is not proven, stocking up on some essential vitamins like calcium, potassium and minerals can give you more strength to fight the symptoms.
4. Herbal remedies: They've been around for hundreds of years and you are likely to have an aunt or grandma swear by one of these cures. From ginger to primrose oil, these cures can balance your hormonal activity in a natural way. You will need to experiment to see what really suits your need.

5. Take a break: No matter what physical or emotional manifestation you suffer, it can double up because of stress and lack of sleep. Knowing your 'off' days, its best you find a way to take some time off for yourself at a spa or try meditation and deep breathing. Do what you love to do to keep your mind calm and clear. Listen to music, take a walk with your dog or simply read a good book.

To start with, change your diet, take a few supplements and herbs, and start exercising, and you should see the change in the first few cycles itself.

Your ovulation cycle is largely ignored until you decide to have a baby. Suddenly, the ovulation cycle becomes more than just a countdown to your next period. When you're trying to get pregnant, you need to identify when you're ovulating to calculate the time available to you to conceive a child. Ovulation occurs mid cycle, every month for most women. It is usually accompanied by a number of symptoms. Some of these are:

Ovulation pain
Some women may experience an abdominal pain when they ovulate. This can range from a mild sensation to a constant pain. The latter is not normal and may be caused by ovarian cysts or scarring by a previous surgery. 

Higher Basal body temperature
Basal body temperature is the lowest temperature recorded in the body when it is at rest. At the time of ovulation, this temperature normally increases as a result of the release of progesterone. To use this method to determine ovulation, you will need a basal thermometer. Take your temperature every morning as soon as you wake up and record it in a chart to spot temperature changes. Basal body temperature can also be used to determine if recent intercourse has resulted in a pregnancy or not. If the basal temperature remains elevated for 18 days after intercourse, it is safe to say that you are pregnant. 

Cervical mucus
The mucus released by the vagina changes according to the stage of the ovulation cycle. This is caused by the fluctuations of hormone levels. At the time of ovulation, cervical mucus is clear, slippery and highly elastic. This can be compared to a raw egg white in colour and consistency. After ovulation, this mucus will turn stickier and denser. 

Cervical position
Your cervix itself will shift at the time of ovulation. Some women can easily feel this change while it may take a little time for others to identify it. The cervix is usually positioned low and feels hard and closed. However, just before oOther signs of ovulation includevulation, it will usually open up and soften a little as well as pull back. Cervical position also needs to be regularly charted to determine when the position changes. 

Spotting
Spotting mid cycle is not always a sign of an early period. It may also signal ovulation. This is usually a result of the sudden drop in estrogen that precedes ovulation. Since the progesterone levels are not high at this time, the lining of the uterus may leak a little blood. 

Other signs of ovulation include:

*  Breast tenderness
*  Heightened sense of smell, taste etc
*  Increased libido
*  Increased energy levels and
*  Water retention
 

The amount of emotional upheaval that periods, or no periods (for that matter) can cause, is something that every woman is aware of. It's normal to miss your period for different reasons occasionally, but develops to be a concern if this absence persists over a period of time. The condition is then termed as a case of secondary amenorrhea. Although most people are quick to consider pregnancy while dealing with the various reasons for missed periods, there are a number of possibilities which are seldom mulled over but should be considered in order to take the effective precautions and seek proper medical care:

WEIGHT
Body weight is responsible for affecting the hypothalamus and this may, in turn, upset your menstrual cycle. BMI level under 18-19 may result in triggering irregularities since enough estrogen will not be created. This is also why underweight women, who suffer from bulimia or anorexia, tend to miss their periods frequently. 
On the other hand, overweight women may stop ovulating due to increase in the production of estrogen and therefore, have heavy, infrequent periods. Therefore, it is essential that body weight be regulated to avoid any disappointment at 'the time of the month.'

STRESS
Any type of physical or emotional stress is bound to affect your cycle. This is because, the production of stress hormones in the body increases and an elevated level of adrenaline and cortisol may impair the functioning of the reproductive system. Under stressful situations, the body employs its amino acids to assist the neurotransmitters to produce stress hormones over sex hormones. As a consequence, the chances of missing your periods increase.

EXERCISING TOO MUCH
While regular workout is indispensable for battling a sedentary lifestyle, overdoing it might cause your body to produce lesser estrogen and delay your periods. Women, who are into athletics and gymnastics, are more likely to suffer from amenorrhea. In fact, other aspects of over-exercising, like sleeping less, fasting, and infections also contribute to such irregularities.

BREASTFEEDING
Prolactin is the hormone that aids in milk production and may also repress ovulation for a while. Many breastfeeding moms may not get their periods for a month or more as a result. But this doesn't do away with your chances of getting pregnant. A span of three months is expected to pass before the abnormalities are done away with.

FOOD ALLERGIES
Celiac disease or untreated gluten allergy can directly harm hormone production. They are directly related to your gut health and your adrenal glands which is why they can influence the sex hormone creation.