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Hi, My son have blood cancer and doctor suggest bone marrow transplant treatment. His age is 4 years and we already did HLA match. His sister is donor for that process her age is 11 years. The HLA report is Half match (50%).so I want to know in half match BMT is possible. What is risk and how much success ratio in this conditions, and how much it cost ,how much time it will take to recover. Please give me answer as soon as possible. Thank u.
The Tulsi plant or holy Tulsi has been an intrinsic part of Indian history. It runs so deep within the realm of our understanding and profession of Hinduism or of an overly eastern way of life, that you use it as a metaphor for sanctity. Most Hindu households, both rural and urban, worship this plant. The benefits of this herb have had the support of a huge mass of people who would not have settled for anything other than a scientific approval of their faith; the humor in this statement eludes most proving every bit of truth in it. Indeed, this healthy herb has been found to be helpful in more than a couple of ways and has thus, transcended the limits of domestic and cultural identities.
See for yourself how healthy is Tulsi:
- Fight off cancer with Tulsi leaves: Tulsi plant is widely sought after for its anti-carcinogenic properties. It is also known to counter bacteria and other viral infections. One may even use its leaves as an antibiotic. Regular consumption of its leaves on an empty stomach can rid you of recurrent problems like fever or cough and cold.
- Pamper your skin with a touch of health: Tulsi is known to detoxify and cleanse the human body. Most skin disorders arise due to underlying skin infections. These infections are usually the result of toxins. Applying a Tulsi pack or drinking herbal teas can therefore be effective.
- Say goodbye to crushing digestive problems: Tulsi can build up your immunity against common conditions like diarrhea or dysentery. People suffering from slow bowel movement have also gained from this herb. It propels good digestion.
- A big threat to mosquito borne diseases: Treatment of Malaria and dengue incurs thousands. Using Tulsi as a preventive herb can be of significant help. Tulsi is also known to cure hepatitis and tuberculosis.
- Bathe in Tulsi water to remedy rashes: Adding Tulsi leaves to your bathing water successfully deals with germs and bacteria. You can easily tackle itchy skin, rashes, and boils with this simple tip. If you wish to discuss about any specific problem, you can ask a free question.
My friend cousin aunt have neck cancer. Plzz give me good advice so we can safe his cousin aunt life. Plzzzz its a request.
What are the reason behind cancer and why should chemotherapy cause baldness? Is chemo drugs are toxic and cause other side effects too?
I am 25 years old. Previously I got surgery for brest lumps at right. Now I got lumps at left side also and I have a lump at my right hand. I went to a gynic, she examined and said it was not harmful. If you want surgery you can if you do not want just leave them. Previous surgery results was also normal. But now I feel swelling under arms on left side. Please suggest me that it is better to go for a surgery for that?
Is there is any treatment of triple negative breast cancer with immunotherapy or is there is any drug that is FDA approved for use in immunotherapy in the patients having triple negative breast cancer.
The term bone marrow transplant is actually a misnomer in the present context as a vast majority of transplants are now conducted by harvesting stem cells from the blood of the donor.
So the correct and logical term now is peripheral blood stem cell transplant. This is just like a blood donation for the donor and poses no risk at all to the donor. The term blood cancer is generally used for leukemias, these can be of two types - acute and chronic.
For the chronic leukemias, especially chronic myeloid leukemia, stem cell transplant is now generally not required as drugs like imatinib, dasatinib and nilotinib are extremely effective. For chronic lymphocytic leukemia transplant is rarely done these days and is generally reserved for relatively younger patients. Even in the imatinib era transplant is an effective procedure and can cure patients with CML (chronic myeloid leukemia) who do not respond to imatinib and other tyrosine kinase inhibitors.
For acute myeloid leukemias stem cell transplant is recommended for all cases except the low risk cases, after completion of chemotherapy. Risk is defined based on kind of genetic mutations in the leukemic cells for acute lymphoblastic leukemia transplant is generally done at relapse, but certain genetic mutations necessitate an earlier transplant, so does presence of or increase in minimal residual disease, which signifies cancer cells not visible to the human eye under the microscope.
Procedure of stem cell transplant HLA matching is done between patient and siblings. Best match is selected as a donor. Matched sibling is the most commonly used donor in blood cancers. In many cases a match is not available, for such cases matched unrelated donor, cord blood, or a partially matched donor (haploidentical donor) is sometimes selected. Donor is given growth factor injection subcutaneously to bring out the stem cells from the bone marrow to bloodstream, twice daily for 5 days. After that the stem cells are collected and stored. Patient is given high dose chemotherapy to kill cancer cells as well as his normal marrow. After chemotherapy, donor stem cells are injected into the body of patient from a vein. After approximately 11-14 days the donor cells get engrafted in the patient's marrow and start producing normal blood cells. The donor cells also kill the cancer cells and prevent cancer from coming back.
Overall depending on whether the patients cancer is controlled or not before transplant the cure rate after transplant can vary from 60 % for patients who have a good control and less aggressive disease biology, to less then 20 % in patients with uncontrolled disease before transplant. Overall, approximately 40 % patients get cured with a transplant. Upto 40 % patients can develop complications, and half of these may be very severe and life threatening. This figure is more in mismatched transplants. Apart from complications, there is still a risk of relapse and these patients need close monitoring in the first few years after transplant.