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My mother 46 was diagnosed with small cell cervix 3B an year back, she went through combination of chemo and radiation. After the PET we came to know it worked wonders and the disease was no more. But not 2 months after the disease recurred. She has received her 2nd line (pacitaxel and irontecan) and 3rd line (vinorelbine and gemcitabine) which were ineffective. Now doctors say that there is nothing they can do about it. If you have found some results with any medicines or chemo or ayurveda please share your experience. She is loosing her health on daily basis as the disease is progressing. I also came to know in some rare case Avastin came to some results in small cell please share. Or even if you can tell about the supportive treatment which makes her a bit stronger Thank you.
Doctor, meri puri body par bhot jyada hair h monkey ki trah, me uper porshan k liye laser therapy lena chahta hu, kya yah sahi rhega half body k liye, aur mujhe bataiye is therapy k bad hair follicles se bhot jyada pasina to nhi aane lagega na. Ya fir follicle working ruk Jane ki vajah se koi r side effects to nhi honge jaise ki pasina na ana ya fir cancer (skin or follicle) kuch years k bad. please mujhe ache se suggest kre. Thank you.
I am 21 year old. I had found some lumps which is small in my left breast. I consult a doctor. He said it is fibroid. It happen 3 years back. I have done sonomammogram. It is about 4 months that I have found difficulty with this. I can feel the lump. It's not pain. But the bone near my neck pain and there is discharge when I press my breast area. When I consult the doctor again he said there is lump on the other breast too. Now there some pain on hand. Sometime there is small pain on vaginal area. The skin of breast is changed and it looks like as that of old womens. Some patches have seen. My under area of breast is dark colour now. The armpit also pain. Feeling tired than before. My doctor told to do mammogram. I fear whether I am having any breast cancer. I have mouth ulcers most of the time.
I'm of 67 years old, suffering from difficulties due to enlarged prostate glands for the last 2 years. A super special doctor has diagnosed the case after several tests and prescribed to consume WELTAM 0.4 tabs daily once. Still going thr'u with the same problems I had before meeting the doctor. please advice.
I had mild pain in my jaws, pain in one ear and soar throat for a fortnight. Now it is getting reduced. I smokes two to three cigarettes a day and afraid of oral cancer. Do I have to wait for few more days or to consult a doctor immediately.
The rising incidences of cancer have made it important for us to be vigilant about our health. It has been proven medically that if cancer is detected at an early stage -stage I & II , then the chances of cure and treatment along with full recovery are very high. For early cancer detection & for people at greater risk of cancer, PHC-Preventive Health Care plays a major role. Preventive Health Check is particularly important for the people who have a family history of cancer.
Almost all cancers are caused by damage or mutation in their genes, which, may be acquired from environmental exposure, dietary factors, hormones or through normal aging. In 90% of cases, these genes are not passed from parents to children. These are known as sporadic mutations and the cancers that they cause are called as sporadic cancers. But 5-10% of cancers are caused by gene mutations which are inherited from one or both parents & passed on to the children .These are hereditary or germline mutations & these cancers are known as hereditary or familial cancers.
People /children, who carry gene mutations have a higher risk of developing cancer at an earlier age or at some point in their life time.
Some of the common such cancers, which run in families, are:
- Breast cancer
- Ovarian cancer
- Colo-rectal cancer (cancer of large intestine )
- Prostate cancer
Breast, ovary & colo-rectal carcinoma have well established gene mutation studies.Mutation of BRCA 1 & BRCA2 Genes is responsible for 85% of hereditary breast cancers.
Estimated life time risk for developing breast cancer in woman with BRCA1 & BRCA2 mutation is 56-87% & risk for developing-bilateral /contralatral breast cancer is about 20-40%. These statistics make a preventive health check for women with breast cancer history in their family a necessity. Mutation in these genes confers about 20-40% increased life time risk for developing ovarian cancer. Hence the presence of gene mutation for breast cancer can trigger ovarian cancer.
However as stated above, other environmental and lifestyle factors can also cause breast cancer other than genetic BRCA1 & BRCA 2 gene mutations.
- Increasing age
- Early menarche
- Late menopause
- First birth after the age of 30
- Atypical lobular hyperplasia or Atypical ductal hyperplasia
- Prior breast biopsies
- Long term postmenopausal estiogen replacement
- Early exposure to ionizing radiation
Other Familial Cancers:
Familial cancer syndromes associated with colo-rectal cancers are familial adenomatous polyposis (FAP).It is an autosomal dominant inherited syndrome with more than 90% penetrance, manifested by hundreds of polyps developed by late adolescence .The risk of developing invasive cancer is almost 100% .So such patients should start getting colonoscopy at an earlier age- say by 20yr of age & should undergo Total Collectomy on development of significant polyps .
Other familial cancer syndromes are hereditary non -Polyposis Colo Rectal Cancer (HNPCC), Gardner's Syndrome, Turcot's Syndrome, Peutz-Jeghers Syndrome, Juvenile Polyposis.
Cancer Assessment & Conclusion:
For breast cancer risk assessment, we have the GAIL model & IBIS model, which take into consideration ,all the risk factors, apart from BRCA1 & BRCA 2 gene mutation. These models calculate the over all life time risk of development of breast cancer for any lady. For this, you have to consult a specialist experienced in area of hereditary cancers, cancer risk assessment, genetic counseling & testing.
To conclude, all people with cancers in their family should undergo genetic testing & counseling, to detect high risk individuals should take adequate measures & treatment.