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I am suffering with hepatic parenchyma. My CEA level is 18 and CA 19.9 is 2.what is the cause of high CEA level. What is the next test to be done. I use liquor and cigarettes.
As per a study conducted by the Copenhagen University Hospital, it was revealed that consuming paracetamol during pregnancy can be detrimental for your baby, as it can weaken the development of the reproductive system of female offspring. The research was published in Endocrine Connections journal.
Although, paracetamol is an over-the-counter treatment for pain relief that is commonly taken by pregnant women worldwide. The study was conducted on three individual rodents and the results indicated that the rodents, who were given paracetamol during pregnancy at doses equivalent to those that of a pregnant woman may take for pain relief, produced female offspring with fewer eggs.
Further, Dr. Kristensen said, "Although this may not be a severe impairment to fertility, it is still of real concern since data from three different labs all independently found that paracetamol may disrupt female reproductive development in this way, which indicates further investigation is needed to establish how this affects human fertility."
Cancer cells use Unfolded Protein Response (UPR) to slow protein synthesis when needed, in order to, suppress body’s circadian clock, which enables them to survive in conditions that would kill normal cells, states a research conducted by the Medical University of South Carolina (MUSC) in the US.
Circadian clock of the body is the 24-hour physiological process cycle and is important in determining the sleeping and feeding patterns of human beings.
“What a tumor cell is doing is taking a pathway that is already in the cell and using it to its advantage,” said J Alan Diehl, senior researcher on the paper published in the journal Nature Cell Biology.
According to a recent study conducted, researchers found that a healthy lifestyle can help fight dementia. As physical activity will help in stimulating the blood circulation in areas that are at risk.
Alice Hollamby, study’s lead author stated, "We understand that living with dementia poses many challenges to individuals and their families and the idea of improving their physical fitness may seem like an unachievable target."
And, Dr. Eddy J Davelaar, study co-author, mentioned, "We all know we should embrace a healthy lifestyle to strengthen our physical and mental wellbeing. However, this is not to say that when one develops dementia, all hope is lost."
Also, as per previously conducted studies, it was found that physical fitness may help prevent dementia, the current study further showed that it can ward off further memory loss in patients suffering from it.
As per a recent study, women who suffer from sleep disorders are more at risk of infertility as compared to others. However, previously conducted studies linked sleep apnea specifically with infertility.
Further, the study states that the risk of infertility is likely to increase with habits such as stress, drinking, smoking, unhealthy habits, STDs and obesity. This new study offers evidence to show that women with sleep difficulties need to pay focus on healthy habits in order to ensure proper sleep if they are trying to conceive.
As per a recent research, an addictive party drug Ketamine, when administered in low-dose can actually help in reducing suicidal thoughts in depressed people within hours.
According to Michael Grunebaum from the Columbia University Medical Center in the US., “there is a critical window in which depressed patients who are suicidal need rapid relief to prevent self-harm.”
Grunebaum further mentioned, “currently available antidepressants can be effective in reducing suicidal thoughts in patients with depression, but they can take weeks to have an effect.”
The study was conducted on 80 people having clinically significant suicidal tendencies, who were assigned to receive an infusion of low-dose Ketamine. It was observed that within 24 hours, those who received an infusion of low-dose of Ketamine showed a significant reduction in suicidal thoughts. The complete study was published in American Journal of Psychiatry.
Pregnant women face double the risk of miscarriage when exposed to non-ionizing radiation emitted from the laptop, smartphone and even bluetooth devices, as per a recent study. The study was conducted on 913 pregnant women over the age of 18 years and were made to wear a small magnetic-field monitoring device for 24 hours.
The increased risk of miscarriage associated with high magnetic fields was consistently observed regardless of the sources of high magnetic fields. After controlling for multiple other factors, women who were exposed to higher magnetic fields, showed 2.72 times the risk of miscarriage than those with lower magnetic fields exposure. The study was published in the journal Scientific Reports.
Diabetes can increase the incidence of kidney dysfunction is quite well known, but as per a recent study conducted kidney disease can also increase the risk of diabetes. Researchers from the Washington University in the US deduced that a likely culprit of the two-way relationship between kidney disease and diabetes is urea.
The findings, published in the journal Kidney International, are significant because urea levels can be lowered through medication and diet, for example, by eating less protein. These findings are of great help as they give a better understanding of the kidney disease, elevated levels of urea and the increased risk of diabetes in the body.
It may be tempting to let your kids stay up late playing games on their smartphones, but using digital devices before bed may contribute to sleep and nutrition problems in children, according to Penn State College of Medicine researchers.
After surveying parents about their kids' technology and sleep habits, researchers found that using technology before bed was associated with less sleep, poorer sleep quality, more fatigue in the morning and -- in the children that watched TV or used their cell phones before bed -- higher body mass indexes (BMI).
Caitlyn Fuller, medical student, said the results -- published in the journal Global Pediatric Health -- may suggest a vicious cycle of technology use, poor sleep and rising BMIs.
"We saw technology before bed being associated with less sleep and higher BMIs," Fuller said. "We also saw this technology use being associated with more fatigue in the morning, which circling back, is another risk factor for higher BMIs. So we're seeing a loop pattern forming."
Previous research has found associations between more technology use and less sleep, more inattention, and higher BMIs in adolescents. But even though research shows that 40 percent of children have cell phones by fifth grade, the researchers said not as much was known about the effects of technology on a younger population.
Fuller said that because sleep is so critical to a child's development, she was interested in learning more about the connection between screen time right before bed and how well those children slept, as well as how it affected other aspects of their health.
The researchers asked the parents of 234 children between the ages of 8 and 17 years about their kids' sleep and technology habits. The parents provided information about their children's' technology habits, sleep patterns, nutrition and activity. The researchers also asked the parents to further specify whether their children were using cell phones, computers, video games or television during their technology time.
After analyzing the data, the researchers found several adverse effects associated with using different technologies right before bed.
"We found an association between higher BMIs and an increase in technology use, and also that children who reported more technology use at bedtime were associated with less sleep at night," Fuller said. "These children were also more likely to be tired in the morning, which is also a risk factor for higher BMIs."
Children who reported watching TV or playing video games before bed got an average of 30 minutes less sleep than those who did not, while kids who used their phone or a computer before bed averaged an hour less of sleep than those who did not.
There was also an association between using all four types of technology before bed and increased cell phone use at night, such as waking up to text someone, with watching TV resulting in the highest odds.
Fuller said the results support new recommendations from the American Academy of Pediatrics (AAP) about screen time for children. The AAP recommends that parents create boundaries around technology use, such as requiring their kids to put away their devices during meal times and keeping phones out of bedrooms at night.
Dr. Marsha Novick, associate professor of pediatrics and family and community medicine, said that while more research is needed to determine whether multiple devices at bedtime results in worse sleep than just one device, the study can help pediatricians talk to parents about the use of technology.
"Although there are many benefits to using technology, pediatricians may want to counsel parents about limiting technology for their kids, particularly at bedtime, to promote healthy childhood development and mental health," Novick said.
In order to provide tailored treatment choices to a maximum number of patients, researchers from Stanford University in the US have defined five new categories of mental illness that will cut across the current broad diagnoses of anxiety and depression.
The five categories are general anxiety, tension, anhedonia, melancholia and anxious arousal. These categories are primarily defined by their specific symptoms and areas of brain activation.
This step was taken, in order to provide guided treatment to millions of patients who suffer from these problems worldwide. In India, as per WHO the number of people who suffer from depression and anxiety is 5 and 3 Crore respectively.