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Overview

Martifur 100 MG Tablet

Manufacturer :  Walter Bushnell
Medicine Composition :  Nitrofurantoin
Prescription vs OTC : Prescription by Doctor not required

About Martifur 100 MG Tablet

Martifur 100 MG Tablet is administered to cure UTIs caused by a few typical kinds of bacteria. Lung inflammation is one of the major but very rare side effects of Martifur 100 MG Tablet and usually occurs if the usage persists for more than half a year.

Damage to the liver is also another serious but infrequent adverse reaction of Martifur 100 MG Tablet. If the therapy is a long term one, then certain tests will be administered to check whether all is good with liver functioning or not. Signs of liver damage include persistent itching, yellowing of the eye’s whites or the skin, vomiting, dark colored urine, nausea and reduced appetite.

Martifur 100 MG Tablet can also result in damage to the nerves. Nerve damage is characterized by pain and numbness of the feet and the hands. Another adverse effect of Martifur 100 MG Tablet is damage to the red blood cells. This condition is known as hemolysis, indicators of which include weakness, fatigue, tiredness and paling of the skin. This generally subsides once the usage is discontinued.

There are certain medications, administration of which is strictly advised against while using Martifur 100 MG Tablet. These include antacids that contain certain ingredients such as magnesium trisilicate, sulfinpyrazone and probenecid.

Pregnant women who are in their term of pregnancy (38 to 42 weeks) should talk to their doctor before using this drug. Also, Martifur 100 MG Tablet is usually advised against at the time of labor and delivery. This drug can be passed onto a mother’s breast milk and thus prove harmful for the baby that is being breastfed.

In case of the elderly, their kidney functioning isn’t usually at their best. Hence, any medicine, once inside their system, tends to stay there for a longer time, thus increasing the risks of various side effects.

    What are the uses of Martifur 100 MG Tablet

    What are the contraindications of Martifur 100 MG Tablet ?

    What are the side effects of Martifur 100 MG Tablet ?

    Key highlights of Martifur 100 MG Tablet

    • How long is the duration of effect?

      The effect of this medication lasts for an average duration of 1 to 3 hours.

    • What is the onset of action?

      This medication is well observed orally. Food may increase the bioavailability of the medicine.

    • Are there any pregnancy warnings?

      Pregnant women must consult doctor before using this medication.

    • Is it habit forming?

      No habit forming tendencies were reported

    • Are there any breast-feeding warnings?

      This medicine is known to excreted through breast milk. This medicine is not contraindicated in children less than 3 months and glucose-6-phosphate dehydrogenase (G-6-PD) deficient infants.

    • Is It safe with alcohol?

      Avoid consuming alcohol while taking this medicine.

    • Is it safe to drive while on this medicine?

      This medicine might cause side effects that affect the alertness of the patient. Thus driving must be avoided.

    • Does this affect kidney function?

      This medicine might be avoided in patients with Clcr <50 mL/minute. Also avoid use in hemo and peritoneal dialysis and continuous arteriovenous or venovenous hemofiltration (CAVH/CAVHD).

    • Does this affect liver function?

      This medicine is probably safe to be used in patient with liver disease. Adjustment of dose might not be needed. Kindly consult for further details.

    What are the substitutes for Martifur 100 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Martifur 100 MG Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose, take the missed dose as soon as you remember.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    How does this medication work?

    The medication belongs to the class urinary anti-infectives. It works by inhibiting the cell wall synthesis by forming reactive intermediates by bacterial flavoproteins. These intermediates will alter the bacterial ribosomal proteins, DNA synthesis, RNA synthesis and cell wall synthesis.

      What are the interactions of Martifur 100 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Consumption of alcohol must be avoided as alcohol may interact with this medicine and cause serious side effects.
      • Interaction with Lab Test

        Causes false-positive urine glucose with Clinitest®.
      • Interaction with Medicine

        • Decreased effect: Antacids, especially magnesium salts, decrease absorption of nitrofurantoin; nitrofurantoin may antagonize effects of norfloxacin.
        • Increased toxicity: Probenecid (decreases renal excretion of nitrofurantoin); anticholinergic drugs increase absorption of nitrofurantoin.
      • Interaction with Disease

        • Use with caution in patients with G-6-PD deficiency, patients with anemia, vitamin B deficiency, diabetes mellitus or electrolyte abnormalities.
        • Therapeutic concentrations of nitrofurantoin are not attained in urine of patients with Clcr <40 mL/minute (elderly).
        • Use with caution if prolonged therapy is anticipated due to possible pulmonary toxicity.
        • Acute, subacute, or chronic (usually after 6 months of therapy) pulmonary reactions have been observed in patients treated with nitrofurantoin.
        • If these occur, discontinue therapy; monitor closely for:
          1. Malaise,
          2. Dyspnea,
          3. Cough,
          4. Fever,
          5. Radiologic evidence of diffuse interstitial pneumonitis or fibrosis.

      FAQs about Martifur 100 MG Tablet

      • Ques : What is Martifur 100 mg tablet?

        Ans : Martifur tablet is a bactericidal antibiotic and contains Nitrofurantoin as an active ingredient.

      • Ques : What are the uses of Martifur 100 mg tablet?

        Ans : Martifur 100 MG Tablet is used for the treatment of urinary tract infection.

      • Ques : What are the Side Effects of martifur 100 mg tablet?

        Ans : Possible side-effects that may occur are weakness, allergic reaction, depression, and bone pain or stiffness.

      • Ques : What are the instructions for storage and disposal Martifur 100 mg tablet?

        Ans : Martifur 100 MG should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

      • Ques : What are the contraindications to Martifur 100 MG Tablet?

        Ans : It should not be used if you have the following conditions such as Hypersensitivity, Impaired renal function, Oliguria or anuria, Pregnancy and neonates.

      • Ques : Is Martifur 100 MG Tablet safe to use when pregnant?

        Ans : This medication is not recommended for use in pregnant women unless absolutely necessary.

      • Ques : Will Martifur 100 MG Tablet be more effective if taken in more than the recommended dose?

        Ans : No, taking higher than the recommended dose can lead to increased chances of side effects.

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Content Details
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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