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Dr. A K Sinha

MS - Ophthalmology

Ophthalmologist, Dhanbad

25 Years Experience
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Dr. A K Sinha MS - Ophthalmology Ophthalmologist, Dhanbad
25 Years Experience
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I'm dedicated to providing optimal health care in a relaxed environment where I treat every patients as if they were my own family....more
I'm dedicated to providing optimal health care in a relaxed environment where I treat every patients as if they were my own family.
More about Dr. A K Sinha
Eye Care (10-1 am) Eye Centre (6.30-8.00 pm)

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MS - Ophthalmology - Banaras Hindu University - 1993
Languages spoken
English
Hindi

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Kutchery Rd, HirapurDhanbad Get Directions
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I have red eyes from four days and burning sensation in the eyes too and burning sensation too?

DHMS (Diploma in Homeopathic Medicine and Surgery)
Homeopath, Ludhiana
I have red eyes from four days and burning sensation in the eyes too and burning sensation too?
Homoeopathic medicine EUPHRASIA 30 ( Dr Reckeweg) drink 2 drops direct on tongue every 2-3 hrly till symptoms lats EUPHRASIA EYE DROPS ( SBL ) pour 2 drops in both eyes 3 times daily
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Dengue Vaxia

M.B.B.S,C.C.A,D.C.A,AASECT,FPA,AAD,M.I.M.S
General Physician, Gorakhpur
Dengue Vaxia

Dengvaxia - first vaccine against dengue

Dengvaxia is a vaccine used to help protect adult or children against dengue disease caused by dengue virus serotypes 1, 2, 3 and 4. Dengvaxia is given to adults, adolescents and children 9 through 45 years of age living in endemic areas.

Read more:

Dengue symptoms and what to do if you think you have denguedengue fever - remedies using papaya leaf juice

Full prescribing info - dengvaxia

Contents

Dengue tetravalent vaccine (live, attenuated).

Indications / uses

Dengvaxia is a vaccine used to help protect adult or children against dengue disease caused by dengue virus serotypes 1, 2, 3 and 4. Dengvaxia is given to adults, adolescents and children 9 through 45 years of age living in endemic areas.

Dosage / direction for use

The patient will receive 3 injections of 0.5 ml each at 6-month intervals.

The first injection will occur at the chosen or scheduled date; the second injection, 6 months after the first injection; and the third injection, 6 months after the second injection. Dengvaxia should be used according to the local vaccination schedule.

If the patient forgot an injection of dengvaxia: if the patient missed a scheduled injection, the physician will decide when to give the missed injection.

It is important that the patient follows the instructions of the physician, pharmacist or nurse regarding return visits for the follow-up injection. If the patient forgets or is not able to go back to the physician, pharmacist or nurse at the scheduled time, ask the physician, pharmacist or nurse for advice.

Administration: dengvaxia is given by the physician or nurse as an injection underneath the skin (subcutaneous route) in the upper arm.

Contraindications

Do not use dengvaxia if the patient is allergic (hypertensive) to the active substances or any of the other ingredients of dengvaxia listed in description (see description); has developed an allergic reaction after prior administration of dengvaxia. Signs of an allergic reaction may include an itchy rash, shortness of breath and swelling of the face and tongue; is suffering from a disease with mild to high fever or acute disease. In this case, the physician will postpone the administration of dengvaxia until the patient has recovered; has a weakened immune system, for example due to a genetic defect, hiv infection or therapies that affect the immune system (for example, high-dose corticosteroids or chemotherapy); is pregnant; is breastfeeding.

Use in pregnancy lactation: dengvaxia must not be given to pregnant or breastfeeding women.

If the patient is of child-bearing stage, the patient should take the necessary precautions to avoid pregnancy for 1 month following administration of dengvaxia; is pregnant or breastfeeding, the patient thinks may be pregnant or is planning to have a baby, ask the physician, pharmacist or nurse for advice before receiving dengvaxia.

Special precautions

Inform the physician, pharmacist or nurse before receiving dengvaxia if the patient is taking an immunosuppressive treatment (prednisone or equivalent to 20 mg or 2 mg/kg for 2 weeks or more). The physician will postpone administration of dengvaxia until 4 weeks after the treatment is discontinued; has experienced any health problems after prior administration of any vaccines. The physician will carefully consider the risks and benefits of vaccination.

As with all vaccines, dengvaxia may not protect 100% of persons who have been vaccinated. Vaccination with dengvaxia is not a substitute for protection against mosquito bites. The patient should take appropriate precautions to prevent mosquito bites, including the use of repellents, adequate clothing, and mosquito nets.

Fainting, sometimes accompanied by falling, can occur (mostly in adolescents) following, or even before, any injection with a needle. Therefore inform the physician, pharmacist or nurse if the patient fainted with a prior injection.

Adults above 45 years of age: adults above 45 years of age should not receive the vaccine.

Driving and using machines: no data are available on the effects of dengvaxia on the ability to drive or use machines.

Use in children: children less than 9 years of age should not receive the vaccine.

Side effects

Like all medicines, dengvaxia can cause side effects, although not all patients get them.

Serious allergic reactions: if any of these symptoms occur after leaving the place where the patient received an injection, consult a physician immediately: difficulty in breathing, blueness of the tongue or lips, a rash, swelling of the face or throat, low blood pressure causing dizziness or collapse.

When these signs and symptoms occur they usually develop quickly after the injection is given and while the patient is still in clinic or physician's surgery.

Serious allergic reactions are very rare (may affect up to 1 in 10, 000 people), after receiving any vaccine.

Other side effects: the following side effects were reported during clinical studies in children, adolescents and adults (from 9 to and including 60 years of age). Most of the reported side effects occurred within 3 days after the injection of the vaccine: very common (may affect more than 1 user in 10): headache, muscle pain (myalgia), generally feeling unwell (malaise), feeling of weakness (asthenia), injection site pain, fever.

Common (may affect up to 1 user in 10): injection site reactions: redness (erythema), bruising (hematoma), swelling, and itching (pruritus).

Uncommon (may affect up to 1 user in 100): infections of the upper respiratory tract, dizziness, sore throat (oropharyngeal pain), cough, runny nose (rhinorrhea), nausea, skin eruption (rash), neck pain, hardening of skin at the injection site (injection site induration).

Additional side effects in adults (from 18 to and including 60 years of age): uncommon (may affect up to 1 user in 100): swollen glands (lymphadenopathy), migraine, joint pain (arthralgia), flu-like symptoms (influenza-like illness).

Additional side effects in children and adolescents (from 9 to and including 17 years of age: uncommon (may affect up to 1 user in 100): itchy rash (urticaria).

Reporting of side effects or any suspected adverse event: if the patient experiences any side effects after vaccination, advised to seek immediate medical attention.

By reporting side effects, it can help provide more information on the safety of the vaccine.

Click to view adr monitoring form

Interactions

Using other medicines and dengvaxia: dengvaxia may not have an optimal effect if it used at the same time as medicines that suppress the immune system such as corticosteroids or chemotherapy.

Inform the physician, pharmacist or nurse if the patient is taking or has recently taken any other vaccines or any other medicines, including medicines obtained without a prescription.

Caution for usage

Before administering any biological, the person responsible for administration must take all precautions to prevent allergic or other reactions. As with all injectable vaccines, appropriate medical treatment and supervision must always be readily available in the event of an anaphylactic reaction following the administration of dengvaxia.

Epinephrine (1: 1000) and other appropriate agents used to control immediate allergic reactions must be available to treat unexpected events such as anaphylaxis.

Dengvaxia must not be mixed with other medicinal products in the same syringe.

Dengvaxia must not be administered by intravascular injection under any circumstances.

Syncope (fainting) can occur following, or even before, any vaccination as a psychogenic response to injection with a needle. Procedures should be in place to prevent injury from falling and to manage syncopal reactions.

Separate syringes and needles, separate injection sites and preferably separate limbs must be used if any other vaccine (s) or medicinal product (s) is/are concomitantly administered.

Dengvaxia is reconstituted by transferring all the solvent (0.4% sodium chloride solution) provided in the blue-labeled pre-filled syringe into the vial of freeze dried powder with a yellowish green flip off cap. The pre-filled syringe is fitted with a sterile needle for this transfer. The vial is then gently swirled. After complete dissolution, a 0.5 ml dose of reconstituted suspension is withdrawn into the same syringe. For injection, the syringe should be fitted with the new sterile needle.

The suspension should be visually inspected prior to administration. After reconstitution, dengvaxia is clear, colorless liquid with the possible presence of white to translucent particles (of endogenous nature).

After reconstitution with the solvent provided, dengvaxia must be used immediately.

Any unused dengvaxia or waste material should be disposed of, preferably by heat inactivation or incineration, in accordance with local regulations.

Do not throw away any medicines via wastewater or household waste. Ask a pharmacist on how to throw away medicines that no longer use. These measures will help to protect the environment.

Storage

Store in a refrigerator. Do not freeze. Keep the vaccine in the outer carton in order to protect it from light.

Description

After reconstitution, one dose (0.5 ml) contains 4.5-6.0 log10 ccid50* of each serotype of the cyd dengue virus** (1, 2, 3 and 4).

* ccid50: 50% cell culture infectious dose.

** produced in serum-free vero cells by recombinant dna technology.

The powder is a white, homogenous, freeze-dried powder with possible retraction at the base, and may form a ring-shaped cake.

The solvent (0.4% sodium chloride solution) is a clear, colorless liquid.

After reconstitution with the solvent provided, dengvaxia is a clear, colorless liquid with the possible presence of white to translucent particles.

Excipients/inactive ingredients: essential amino acids including l-phenylalanine, non-essential amino acids, l-arginine hydrochloride, sucrose, d-trehalose dihydrate, d-sorbitol, trometamol, urea, sodium chloride, water for injections.

Mechanism of action

Dengvaxia contains dengue virus serotypes 1, 2, 3 and 4 that have been weakened. Dengvaxia works by stimulating the body's natural defenses (immune system), which produces its own protection (antibodies) against the viruses that cause dengue disease.

Dengue is a viral infection transmitted to humans through the bite of an infected aedes mosquito. Dengue is not transmitted directly from person-to-person. Nevertheless the virus which replicates in an infected individual can be transmitted to other humans through mosquito bites for 4-5 days (maximum 12 days) after the first symptoms appear.

Dengue disease results in a wide range of symptoms including fever, headache, pain behind the eyes, muscle and joint pain, nausea, vomiting, swollen glands or skin rash. Symptoms usually last for 2-7 days. Dengue disease can also be asymptomatic.

However, occasionally dengue can be severe and potentially lead to hospitalization and in rare cases to death. Severe dengue is characterized by high fever and any of the following symptoms: severe abdominal pain, persistent vomiting, rapid breathing, severe bleeding, bleeding in stomach, bleeding gums, fatigue, restlessness, coma, seizure and organ failure.

Source:- http://www.mims.com/philippines/drug/info/dengvaxia

More information about dengvaxia - first vaccine against dengue

Sanofi awaits govt approval to launch dengue vaccine in india

Sanofi pasteur - dengue vaccine frequently asked questions

14 people found this helpful

Eye Health - 5 Myths Busted!

MBBS, DOMS, MS - Ophthalmology, , Fellowship in phacoemusification
Ophthalmologist, Patna
Eye Health - 5 Myths Busted!

Your eyes are an important part of your health. There are many things you can do to keep them healthy and make sure you are seeing your best. However, there are a number of myths regarding what you should do and what you shouldn't do when it comes to maintaining good eye health.

Here are 5 of those myths busted:

Myth #1: reading in dim light and sitting too close to the tv hurts your eyes

Fact: sitting too close to the tv, you may feel eye strain or get a headache from reading in the dark, but it will not weaken your eyes. It fatigues your eyes but does not harm your eye health in any way.

Myth #2: eating carrots will improve your vision

Fact: carrots are rich in vitamin a, a nutrient essential for good vision. But eating carrots will only provide a small amount of vitamin a. To get the optimum amount, you need to include other sources of vitamin a in your diet as well, some of which are milk, cheese, egg yolk and liver. Spinach is best for eye health. It has lutein and zeaxanthin, both of which can help prevent cataracts.

Myth #3: if you wear glasses or contacts for a continuous period, your eyes will weaken

Fact: your eyes will not grow weaker by using corrective lenses. The prescription may change over time due to aging or absence of disease but it has nothing to do with your current prescription. Some children have correctable eye problems that do require glasses to improve the condition.

Myth #4: when you get something in your eye, rub it out

Fact: this is not true for everything that gets in your eyes. If any particle falls in your eyes dust it off. But if it is sand and small debris that gets in your eye, don't touch it. Use an eye wash for flushing it out. If an object gets stuck in your eye, don't remove it or rub your eye constantly. Visit a doctor at the earliest because some serious injuries may seem minor at first.

Myth #5: dark sunglasses can protect your eyes from the sun

Fact: the color of sunglass does not ensure eye protection. Look for sunglasses that block both uva and UVB rays. Exposure to the UV-rays of sunlight can have cumulative effects on your eyes. It increases your risk for cataracts, solar retinitis, and age-related vision loss. Even if your contacts have UV protection, wear sunglasses that block 100% of uva and UVB rays for full protection. If you wish to discuss about any specific problem, you can consult an ophthalmologist.

3342 people found this helpful

Hi I am having a medium sized lump under my lower eye lid from 3 weeks which is not hurting. I expected it to be gone naturally. But now to the side of the lump I am having a thin inflammation which cannot be noticed but it is paining in that region (which is not the actual lump region). Please suggest anything to reduce pain and inflammation before I consult.

DHMS (Diploma in Homeopathic Medicine and Surgery)
Homeopath, Ludhiana
Hi I am having a medium sized lump under my lower eye lid from 3 weeks which is not hurting. I expected it to be gone...
Homoeopathic medicine SILICEA 6X ( Dr Reckeweg) Chew 4 tab 3-4 hrly. PULSATILLA 30 ( Dr Reckeweg) Drink 2 drops direct on tongue daily night Report after 15 days
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Why my eye no increasing every year now I have 3 no in both eyes pls give knowledge.

FPRS, DNB Ophtalmology
Ophthalmologist, Pune
Why my eye no increasing every year now I have 3 no in both eyes pls give knowledge.
unfortunately there are no natural medications to remove spectacles permanently. you can either try contact lenses or plan for refractive lasik laser surgery
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My left eye is much weaker than my right. I'm using specs since last 4 years. Still I find sometimes uncomfortable to focus at. Left eye power is -2 whereas right is 1.75 with cylindrical power. While sleeping always tears come out from left eye, and sometime it itches also very much. Please suggest what should I do? Any diet change? Anything.

MBBS
General Physician, Jalgaon
My left eye is much weaker than my right.
I'm using specs since last 4 years. Still I find sometimes uncomfortable to...
Please Wake up early do eye exercises daily Do yogasanas and pranayam daily Take Carrots, olendar, awla, green leafy vegetables, papaya regularly Take Cap eye vital 45 1 Put cinereria eye drops by W shwabe Homeopathic medicine 2 drops in both eyes regularly.
2 people found this helpful
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I have red eyes from 2 days and it seems like my eyes are burning what the problem or disease I am suffering.

Fellowship in Comprehensive Ophthalmology, DOMS
Ophthalmologist, Sangrur
I have red eyes from 2 days and it seems like my eyes are burning what the problem or disease I am suffering.
Hello dear there are many causes for redness of eyes mainly allergy, infection, inflammation and dry eyes etc. 1. Redness + itching: allergy 2. Redness + pain+ watering + decreased vision: infection 3. Redness + pain: inflammation 4. Redness+ foreign body sensation: dryness if there is only redness then it is normal as slight exposure to dust, temperature or air or eyes may be red in morning. Stress may also cause redness. I usually do not treat when there is only redness, you can 1. Blink a lot 2. Wash eyes with fresh water 3. Cold compresses 4. Use lubricating eyedrop like flogel these measures will help to keep your eyes healthy but it will not have any effect on redness (treating generalredness alone is not necessary also) having said that you should consult local ophthalmologist for proper examination and treatment.
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Sir I am suffering from weak site of my eyes so please give me a solution and also forgot my hair so please help me.

DHMS (Diploma in Homeopathic Medicine and Surgery)
Homeopath, Ludhiana
Sir I am suffering from weak site of my eyes so please give me a solution and also forgot my hair so please help me.
Being a homoeopath, I will advise you to undergo homoeopathic treatment as homoeopathic medicine along with exercises aand a diet plan are very effective combination for improving eyesight as well a your hair problem. Consult me with exact details of your problem------------------------------
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I'm 25 years old. I am suffering with the problem of EYE floater. AM frustrate from my life pls suggest me some solution. Its too much annoying I see a black dot type 24 hours .pls give me best solution I request you.

Fellowship in Comprehensive Ophthalmology, DOMS
Ophthalmologist, Sangrur
I'm 25 years old. I am suffering with the problem of EYE floater. AM frustrate from my life pls suggest me some solut...
Hello Floaters appear due to condensation of collagen fibrils present in vitreous cavity These are benign and don't need treatment Only way to get rid of them is to avoid them Consult ophthalmologist when floaters increase in number.
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I have red eye for three day and food poisoning and loosnotion and backpain what should I have to do.

FPRS, DNB Ophtalmology
Ophthalmologist, Pune
I have red eye for three day and food poisoning and loosnotion and backpain what should I have to do.
. Dear lybrate user, red eyes could be because of many reasons but commonly it is due to allergy or infection. You need to visit eye specialist to differentiate between the two as the treatment is different. Also get your eyes checked for any glass power.
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