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I think that I have cancer but hesitate to tell my parents I have a very small swelling on left side of neck near jaw And I have rough skin cell on my back which get removed by hand but emerge again Also I feel tiredness and have very light hair fall.
The rising incidences of cancer have made it important for us to be vigilant about our health. It has been proven medically that if cancer is detected at an early stage -stage I & II , then the chances of cure and treatment along with full recovery are very high. For early cancer detection & for people at greater risk of cancer, PHC-Preventive Health Care plays a major role. Preventive Health Check is particularly important for the people who have a family history of cancer.
Almost all cancers are caused by damage or mutation in their genes, which, may be acquired from environmental exposure, dietary factors, hormones or through normal aging. In 90% of cases, these genes are not passed from parents to children. These are known as sporadic mutations and the cancers that they cause are called as sporadic cancers. But 5-10% of cancers are caused by gene mutations which are inherited from one or both parents & passed on to the children .These are hereditary or germline mutations & these cancers are known as hereditary or familial cancers.
People /children, who carry gene mutations have a higher risk of developing cancer at an earlier age or at some point in their life time.
Some of the common such cancers, which run in families, are:
- Breast cancer
- Ovarian cancer
- Colo-rectal cancer (cancer of large intestine )
- Prostate cancer
Breast, ovary & colo-rectal carcinoma have well established gene mutation studies.Mutation of BRCA 1 & BRCA2 Genes is responsible for 85% of hereditary breast cancers.
Estimated life time risk for developing breast cancer in woman with BRCA1 & BRCA2 mutation is 56-87% & risk for developing-bilateral /contralatral breast cancer is about 20-40%. These statistics make a preventive health check for women with breast cancer history in their family a necessity. Mutation in these genes confers about 20-40% increased life time risk for developing ovarian cancer. Hence the presence of gene mutation for breast cancer can trigger ovarian cancer.
However as stated above, other environmental and lifestyle factors can also cause breast cancer other than genetic BRCA1 & BRCA 2 gene mutations.
- Increasing age
- Early menarche
- Late menopause
- First birth after the age of 30
- Atypical lobular hyperplasia or Atypical ductal hyperplasia
- Prior breast biopsies
- Long term postmenopausal estiogen replacement
- Early exposure to ionizing radiation
Other Familial Cancers:
Familial cancer syndromes associated with colo-rectal cancers are familial adenomatous polyposis (FAP).It is an autosomal dominant inherited syndrome with more than 90% penetrance, manifested by hundreds of polyps developed by late adolescence .The risk of developing invasive cancer is almost 100% .So such patients should start getting colonoscopy at an earlier age- say by 20yr of age & should undergo Total Collectomy on development of significant polyps .
Other familial cancer syndromes are hereditary non -Polyposis Colo Rectal Cancer (HNPCC), Gardner's Syndrome, Turcot's Syndrome, Peutz-Jeghers Syndrome, Juvenile Polyposis.
Cancer Assessment & Conclusion:
For breast cancer risk assessment, we have the GAIL model & IBIS model, which take into consideration ,all the risk factors, apart from BRCA1 & BRCA 2 gene mutation. These models calculate the over all life time risk of development of breast cancer for any lady. For this, you have to consult a specialist experienced in area of hereditary cancers, cancer risk assessment, genetic counseling & testing.
To conclude, all people with cancers in their family should undergo genetic testing & counseling, to detect high risk individuals should take adequate measures & treatment.
Hpv vaccine cost for 3 doses. Time limit between the doses. Is it only prevention for cervical cancer?
I have fibroadenoma in my breast can I have the treatment for this please suggest also suggest me the foods. Thanks in advance.
Please. Ask me cancer symptom's. And also define me its precautions. And please also tell me cancer types.
I'm 27 year old. Married no children I been suffering with fibroadenoma 7 years now I see dimpling 3 inches below my under arm it can be seen only when my arm is in air. Some pain also ultra sonography is clear it show 2 fibroadenoma side by side. Dimpling area is clear in ultra sonogram my gp don't see dimpling or puckering. What should I do?
There has been a lot of speculation about bread so should we continue eating bread or not because in the news they are telling that it causes dangerous diseases like cancer please help?
My wife if taking unwanted 21 days from 3 months and she is having breast pain. The pain starts from 10th day once she starts taking pill and continues till 21st day. Then she will not have any pain. Is there anything to worry? Will this pain stops or should I take ipill bcp?
Diets high in saturated fat increase the risk of prostate cancer. As per a report from University of Texas M. D. Anderson Cancer Center in Houston published in the International Journal of Cancer:
Men who consume high saturated animal fat diet are two times more likely to experience disease progression after prostate cancer surgery than men with lower saturated fat intake.
There is also shorter "disease–free" survival time among obese men who eat high saturated fat diet compared with non–obese men consuming diets low in saturated fat.
Men with a high saturated fat intake had the shortest survival time free of prostate cancer (19 months)
Non–obese men with low fat intake survived the longest time free of the disease (46 months).
Non–obese men with high intake and obese men with low intake had "disease–free" survival of 29 and 42 months, respectively.
Take home messages
High saturated fat diet has been linked to cancer of the prostate
Reducing saturated fat in the diet after prostate cancer surgery can help reduce cancer progression.
Cancer prostate has the same risk factors as that of heart blockages and both are linked to high saturated fat intake.
With an increase in number of heart patients, a corresponding increase in prostate cancer patients is also seen in the society.