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स्तन वसा, संयोजी ऊतक, और लोब में विभाजित ग्रंथि ऊतक से बना होता है। स्तन कैंसर तब शुरू होता है जब स्तन में कोशिकाएं नियंत्रण से बाहर निकलने लगती हैं। नलिकाएं का एक नेटवर्क लोब से निपल तक फैलता है। एक स्तन आमतौर पर दूसरे से छोटा होता है। महीने में अलग-अलग समय पर आपके स्तन अलग-अलग महसूस कर सकते हैं स्तनों के लिए आपकी अवधि के ठीक पहले लंपट महसूस करना आम बात है। आपके स्तन महीने में अलग-अलग समय पर अलग-अलग महसूस हो सकते हैं। स्तनों का आपकी अवधि के ठीक पहले लंपट महसूस होना आम बात है।
स्तन कैंसर सामान्यतः कोशिकाओं जो स्तन के नलिकाएं होती हैं, में शुरू होता है। स्तन कैंसर तब शुरू होता है जब स्तन में कोशिकाएं नियंत्रण से बाहर बढ़ने लगती हैं। कोशिकाओं का यह उत्परिवर्तन एक ट्यूमर को जन्म देता है, जिसे एक गांठ के रूप में महसूस किया जा सकता है। अगर अनुपचारित छोड़ दिया जाता है, तो घातक कोशिका अंततः शरीर के अन्य भागों में फैल सकती हैं, एक प्रक्रिया जिसे मेटास्टैसिस कहा जाता है।
स्तन कैंसर के लक्षण
स्तन में एक गांठ आमतौर पर स्तन कैंसर से जुड़ा है, लेकिन अधिकतर समय, स्तन में गांठ कैंसर नहीं होता। किशोरावस्था में हार्मोनल परिवर्तन से लेकर क्षतिग्रस्त वसा ऊतक तक, महिलाओं में शुरुआती 20 से लेकर शुरुआती 50 की उम्र तक सभी स्तन गांठों में से 90 प्रतिशत से ज्यादा गैर-कर्कश (सौम्य) हैं।
स्तम्भों में लंप्स स्तन संक्रमण, फाइब्रोकाइसटिक स्तन रोग (ढेलेदार स्तन), फाइब्रोएडीनोमा (गैर-कन्सेसर ट्यूमर), वसा-परिगलन (क्षतिग्रस्त ऊतक) जैसे कई अन्य कारणों के कारण हो सकते हैं।
यद्यपि अधिकांश स्तन गांठ कम गंभीर स्थितियों के कारण होते हैं, नए, पीड़ारहित गांठें फिर भी स्तन कैंसर का सबसे आम लक्षण हैं। एक महिला अपने स्तन में बदलाव देख सकती है, और मामूली असामान्य दर्द जो दूर जाता प्रतीत नहीं होता। इन परिवर्तनों के लिए देखें:
1. स्तन या निपल का अलग महसूस होना:
- निपल कोमलता, या स्तन या अंडरआर्म क्षेत्र में या उसके पास एक गांठ या मोटा होना।
- त्वचा की बनावट में परिवर्तन या स्तन की त्वचा में छिद्रों का इज़ाफ़ा
- स्तन में एक गांठ
2. दिखने में बदलाव:
- स्तन के माप या आकार में कोई भी अस्पष्टीकृत परिवर्तन
- स्तन पर कहीं भी गढ़ा
- स्तन की अस्पष्ट सूजन (खासकर अगर यह केवल एक तरफ है)
- स्तन का अस्पष्ट संकुचन (खासकर अगर यह केवल एक तरफ है)
- निप्पल जो थोड़ा सा आवक हो जाता है, या उलटा हो गया है
3. निपल निर्वहन:
किसी भी प्रकार के निप्पल निर्वहन, विशेष रूप से साफ़ निर्वहन या खूनी निर्वहन स्तन कैंसर का संकेत हो सकता है। एक दूधिया निर्वहन जब महिला स्तनपान नहीं कर रही है, हालांकि स्तन कैंसर से जुड़ा नहीं है, लेकिन एक डॉक्टर द्वारा जांच कराया जाना चाहिए।
इन लक्षणों में से एक या अधिक होने का मतलब यह नहीं है कि आपको स्तन कैंसर है। यदि आप इन संकेत और लक्षणों में से किसी का अनुभव करते हैं, तो एक पूर्ण मूल्यांकन के लिए अपने चिकित्सक को देखें।
Cancer that originates in the bones of a human body is referred to as bone cancer. Any bone could come under the threat of this disease, but generally the longer bones of your body, so to say the bones of your limbs, are at a greater risk.
A few factors that might push you an inch closer to bone cancer are:
- Genes could jinx your health: A few typical genetic syndromes could increase a person's chances of contracting bone cancer. These syndromes could have been active in any person belonging to your lineage. One such syndrome is Li-Fraumeni.
- Treatment for one kind of cancer can make you prone to some other kind: Radiation affects your bones adversely. A patient of breast cancer might be undergoing radiation therapy that further increases his or her risk of contracting bone cancer in future.
- Paget's disease can have unfavorable implications: Paget's disease is a disease that affects elderly people. This condition, if left untreated, can turn into bone cancer at a later stage.
Several symptoms of bone cancer can be found below:
- Sudden loss of weight: If you lose a considerable amount of weight in a few weeks time without having made any effort at all, you should probably be worried about the health of your bones. Bone cancer can result in sudden and unintentional weight loss.
- Unexpected bone fracture or breakage: Cancer of the bones is known to gnaw at the strength of your bones. Weakened and diseased bones can break or get fractured very easily. An unexpected fracture should not be overlooked so as to prevent chances of anything more harmful.
- Long spans of unyielding exhaustion: Constant fatigue and sleepiness might be hinting at a more serious underlying problem. The bones in your body hold you together; cancerous bone cells can make you feel exhausted without much exertion as your bones lose their inherent potency.
- Persistent pain in the bones: Excruciating cramps or pangs of stinging pain in a person's bones either continuously or at odd hours, could be indicative of bone cancer. Such instances require the advice and guidance of an experienced oncologist.
- Bone swelling: The area affected by bone cancer can grow big and tender or the bone itself can swell up.
In case you have a concern or query you can always consult an expert & get answers to your questions!
Breast Cancer is cancer that develops in the cells of the breasts. In the United States, breast cancer happens to be the second most common cancer diagnosed in women. General signs and symptoms of breast cancer include, a lump in the breast, noticeable change in breast shape, liquid oozing out from the nipple, there might be a newly inverted nipple or a red patch of skin. Before going into the treatment and most importantly see how can this be prevented from affecting women, we will look closely into the causes, which lead to breast cancer.
Prevention of breast cancer
Doctors do not guarantee that breast cancer can be prevented. Still, women can be cautious and through reviewing the risk factors, that lead to development of cancerous cells or increase the chances of them getting affected, can go a long way in minimizing the risk.
Some of the preventive measures are:
- Keeping a good body weight is a must. Being overweight increases the risk of breast cancer.
- Risk of breast cancer can be reduced through medicines like tamoxifen and raloxifene. Both these medicines block the effects of estrogen on breast tissue.
- Aromase inhibitors, as medications, can be used to prevent the production of small amounts of estrogen, which are usually produced in women during post menopause period.
- Group of patients, who have a very high risk of breast cancer, removal of breasts through surgery is an options which doctors consider to prevent this from happening.
- Having healthy diet is a must. Taking more of fruits, vegetables, whole grains, legumes, nuts is desirable if you want to keep yourself away from this dreaded disease.
The brain is not a stagnant realm fed with a granted quota of intelligence and memory at birth. It is always in a state of flux. Exercising your brain in various ways accelerates its ability to perform better. It is in your hands to have a sharper take on situations and occurrences. Playing games that require brainstorming, solving quizzes, crosswords or playing chess makes you feel rejuvenated and tired at the same time; the reason being activated brain cells. A healthy brain will affect your life decisions positively and you probably will think rightly before you leap.
Tips to exercise those brain cells:
- Meditate and calm your mind: Ten minutes of meditation each day can help you get over anxiety. When your mind is at peace you think out pros and cons with enhanced insight. This composure reflects in each of your actions. Meditation demands your brain to be quiet when it is accustomed to work; you therefore have greater control over it.
- Music can improve your brain abilities: Music is the best antidote for a sloppy brain. Music excites the neurons healing a bruised memory. It gifts you with clarity of thought. Apart from listening to music one must try to play a musical instrument. Teaching yourself things puts your mind through a strict regimen of constructive activities.
- Take out time to learn a new language: We are paralyzed the minute our brain gives up. Due to several external and internal reasons each one of us is likely to suffer from cognitive disorders on being subjected to extreme pressure or shock. Trying to learn a new language motivate your brain cells to have a wider vocabulary, which further restricts your chances of brain damage.
- Mental mathematics could better your intelligence: Calculators, computers and phones are ridding us of our ability to compute individual data. Computation and consolidation of data helps your mind to work faster with precision. So, you now know those lessons on mental mathematics in childhood were actually the key to a well rounded brain.
- Think of something novel: The more the number of neurons the merrier is your brain. Take pains to direct your mind on a novel track. Thinking beyond what is given and expected helps your brain grow new neurons. It builds up your creativity letting you discover more of your capabilities. Consult an expert & get answers to your questions!
I am a male aged 52 yrs. I have slip disc problem because of which my left hand becomes senseless as soon as I do some work with it. This problem is there for past 8- 10 yrs. I also have severe back pain from time to time. Please suggest remedy, if any.
It is perfectly normal for women to experience the periodic monthly bleeding cycle. However, if a woman experiences uterine bleeding which is abnormal and dysfunctional, it could be a symptom of infection. Other causes of abnormal uterine bleeding include hormonal imbalance, infection in cervix and cancer of the uterus. Many women can also experience abnormal uterine bleeding during first trimester of pregnancy.
The following are considered to be abnormal or dysfunctional uterine bleeding:
- A menstrual cycles occurs between 21 to 35 days, anything shorter or longer than this is abnormal
- No period for 3–6 months (amenorrhea) is abnormal
- Spotting or bleeding between periods
- Spotting or bleeding after intercourse
- Bleeding that is heavier or lasts longer than usual
- Spotting or bleeding after menopause
What can cause such a situation?
Some of the common causes leading to abnormal bleeding are as follows:
- Ectopic pregnancy
- Cervical or uterine infections
- Hormonal imbalances
- Problems with blood clotting
- Polycystic ovarian
- Endometrial hyperplasia
- Cancer of the reproductive tract
How to Diagnose it?
Most women tend to ignore abnormal bleeding, taking it as something to do with age or hormones. A detailed physical examination and history is done to understand menstrual cycle patterns and family history. In addition, the following would be used.
- Ultrasound: The pelvic organs are examined through sound waves to locate the problem area
- Hysteroscopy: Through a thin device that is inserted into the vagina, the doctor takes a look at the inside of the organs and identify the cause for the bleeding
- Endometrial biopsy: The uterine lining tissue is removed and examined under microscope to look for tissue changes that could be causing the bleeding
How Best to Treat It?
This would depend on the reason for the abnormal bleeding. However, in most cases, combinations of the following are useful in treatment.
- Hormone replacement can be done depending on the age and gynecological history, the type and the dose of the hormone would be decided upon. These could be in the form of tablets, vaginal creams, injections, or through an intrauterine device
- Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen are useful in reducing bleeding and controlling cramps during excessive menstrual bleeding.
- Antibiotics may be useful if there is infection of the pelvic organs.
- Polyps, cysts, cancers, and other growths can be removed via hysteroscopy and sent for biopsy to confirm they are not cancerous.
- Endometrial ablation where the endometrial tissue is treated with heat can be used to control bleeding permanently.
- Hysterectomy would be done if other forms of treatment have failed. This could depend on their gynecologic history and other considerations as she cannot get pregnant after this.
Do not ignore if you see a change in the pattern of your uterine bleeding. It definitely calls for medical attention and if identified early, can be managed in much simpler ways. If you wish to discuss any specific problem, you can consult a gynaecologist.
Hi Sir, I want to go to gym. I have suffered from slip disk a year ago at my back. Can I lift weights?
The uterus is set up inside the pelvis with different muscles, tissue, and tendons. Due to pregnancy, labour or complicated delivery, in a few ladies, these muscles tend to weaken. Additionally, as a woman ages and with a loss of the hormone oestrogen, her uterus can drop into the vaginal canal, bringing about the condition known as a uterine prolapse.
The following conditions can bring about a prolapsed uterus:
- Pregnancy with complicated or even ordinary delivery through the vagina.
- Weakness in the pelvic muscles with the increase in age.
- Weakening and loss of tissue after menopause and loss of normal oestrogen.
- Conditions leading to increased weight in the abdomen, for example, constant coughing (with bronchitis and asthma), straining along with constipation, pelvic tumours (uncommon), or clogging of liquid in the abdomen.
- Being overweight puts extra strain on pelvic muscles.
- Previous surgery in the pelvic region leading to loss of outer support
However, this condition can be treated effectively:
- Self care at Home: You can strengthen your pelvic muscles by performing Kegel workouts. You do these by contracting your pelvic muscles, as though attempting to stop the stream of urine. This exercise makes the pelvic muscle strong and gives some support. Have your specialist train you on the best possible approaches to exercise your muscles.
- Medications: Oestrogen (a hormone) cream or suppository ovules or rings embedded into the vagina help in strength and endurance building of the tissues in the vagina. However, oestrogen is just for use in some of the postmenopausal ladies.
- Surgery: Based on your age and whether you wish to conceive a child naturally, surgery can repair the uterus or remove it. The uterus as in many cases can be expelled with a hysterectomy. During the surgery, the specialist can repair the hanging or saggy vaginal dividers, urethra, bladder, or rectum. The surgery might be performed by an open abdomen procedure, through the vagina, or through little cuts in the abdomen or vagina with particular instruments.
- Other Therapy: In case that you do not need surgery or have a poor possibility for surgery, you may choose to wear a steady gadget, called a pessary. It is worn in the vaginal tract to strengthen the falling uterus. It can be utilised briefly or can be long-lasting. They come in different shapes and sizes and should be fitted according to the person. In case that the prolapse is extreme, a pessary may not work. Prolapse surgery is always preferred by vaginal route. Likewise, pessaries can disturb the insides of the vagina and may bring about a noxious release.
It can be prevented in the following manner:
- Decrease your weight.
- Try to avoid constipation by consuming a high-fiber diet.
- Do Kegel exercises to strengthen the pelvic muscles.
- Stay away from heavy lifting or straining.
In case you have a concern or query you can always consult an expert & get answers to your questions!
Breast cancer begins when cells in the breast(s) start to grow out of control. It is understood as being the most common cancer, seen predominantly in females, globally. It is reasonably treatable and often curable.
1. Type: Adenocarcinomas constitute more than 95% of breast cancers with infiltrating ductal carcinoma (IDC) being the most common form of invasive breast cancer.
Frequently occurring breast cancers present as one of the following types mainly
1. Ductal Carcinoma In Situ (DCIS): Is the most common type of non-invasive breast cancer and is confined to the milk ducts of the breast. There is no invasion in the basement membrane. Pure DCIS metastasizes rarely. Non comedo cribrioform carcinoma is the most common DCIS found which, when compared to the comedo type, is mostly non-aggressive.
2. Infiltrating Ductal Carcinoma (IDC): Represents majority (about 3/4th) of the breast cancers, and is known to metastasize commonly to bones, lungs and liver.
3. Lobular Carcinoma In Situ (LCIS): Develops in multiple lobules of the breast (bilaterally). LCIS is less commonly seen, compared to DCIS.
4. Infiltrating Lobular Carcinoma (ILC): Represent about a tenth of all breast cancers and tends to metastasize to other regions of the body.
Less commonly occurring breast cancers such as
5. Inflammatory Breast Cancer: Is relatively uncommon and are caused probably owing to viral infections. The breast is warm, red and swollen.
6. Paget’s disease of the nipple: Is a rare form of breast cancer. It begins in the milk ducts and spreads to the nipple and areola.
7. Medullary Carcinoma
8. Mutinous Carcinoma
9. Tubular Carcinoma
10. Phylloides tumor etc all.
2. Gender: Affects the female populace predominantly. However, a small percentage of breast cancer is attributable to the male populace as well.
3. Etiology: No definite cause is known. However, diet, lifestyle, environment, hormonal/ reproductive factors, personal or family history of breast cancer especially in first degree relatives and also any benign breast disease history etc all are known to increase the risk of breast cancers. Specifically, excessive fatty diet, obesity, type 2 diabetes mellitus, benign breast disease, heredity/ inheritance of mutated breast cancer genes 1 (BRCA1) and 2 (BRCA2), smoking, alcohol intake, infertility, estrogen therapy/ hormone replacement therapy (long term) in post menopausal women, delayed age at first pregnancy, nulliparity (not having child), early menstruation, delayed onset of menopause, lactating mothers not breast feeding, exposure to ionizing radiation, sedentary lifestyle, depression, exposure to MMTV virus etc all can potentially increase the risk for breast cancer.
4. Features: Signs & symptoms, of breast cancer, manifest majorly in the following ways
Lump/ nodule in the breast that gets attached to the skin of the breast over time. The lump / nodule could be hard and painless with irregular edges or it could also be soft, rounded, tender and painful.
Enlarged lymph nodes in the axilla which are palpable.
Swelling of whole or a part of a breast. This is even if there is no distinct lump felt.
Retraction or thickening of the nipple(s).
Pain in the breast or nipple.
Discharge from nipple other than breast milk.
Irritation/ scaliness of skin over the breast.
Redness of nipples
Rarely, red, swollen and tender breast.
5. Screening: Is generally recommended for asymptomatic populations goal of which, as usual, is to be able to detect & diagnose breast cancer at an early stage which is potentially curable. It is mostly radiologic with mammography/ USG being instrumental in raising suspicions for further diagnostics (i.e. biopsy) that help detect breast cancer, if any, early.
6. Diagnosis: A self-examination/ clinical exam of the breast(s)/ axilla that reveals a palpable mass prompts the following diagnostics. Abnormal blood test results may be indicative of malignancy, but a follow up imaging/ biopsy is always the gold standard for accurate diagnosis.
- Blood: ER/ PR/ HER2/neu, uPA, PAI-1, CA15-3, CA27.29 etc all tumor markers are helpful.
- Imaging: Mammography/ USG Scan usually, as relevant. Again, CT Scan of abdomen & pelvis and chest, PET CT scan, bone scan etc all help detect metastasis, if any, for cancers in stage III & above.
- Biopsy: either excisional, incisional, fine needle aspiration (FNA) or core biopsy technique, as contextually appropriate, is frequently employed and a histopathological examination (HPE) thereof clinches the diagnosis and the nature of the disease.
7. Treatment: Conventional treatment includes surgery, radiotherapy, hormone therapy/ chemotherapy as deems appropriate. Simultaneously, an adjunctive or integrative naturopathic treatment with suitable complementary & alternative medicines (CAM) too can help improve clinical outcomes and facilitate recovery as would be feasible contextually.
8. Prognosis: Preventive measures, earlier diagnosis and right early treatment is key for an effective therapeutic management & better prognosis. Like most other cancers, the chances of cure for an early stage breast cancer are more. The cure/ recovery chances are influenced by the type, grade, stage of cancer, recurrence and the patient’s general health & vitality etc all. Above-mentioned apart, age, menopause status, lymph node status, ER/ PR/ HER-2/ neu status, size & extent of breast cancer etc all also influence the treatment outlook in breast cancer. The five year survival rate is strongly correlated with the stage of breast cancer.
9. Prevention: Rightly said, prevention is always a better choice. Although genetic risks are difficult to modify, still an increased focus on protective factors and avoidance of the risk factors can be of help. An adherence to a Mediterranean diet, maintaining an ideal body weight and an active lifestyle with due emphasis on regular exercising (for at least 30 minutes daily), de-stressing and relaxation is highly recommended for reducing the risks of breast cancer. A healthy eating plate comprises essentially a low fat diet, fibre rich foods including whole grain cereals, green leafy vegetables cooked using healthy vegetable oils, fresh fruits of all colours as seasonally available and healthy proteins/ fats including fresh fish, poultry, beans, nuts etc all. It is advisable to limit milk/ dairy, preferably of low fat content, to 1 to 2 servings max daily. Although alcohol is optional and is not for everyone, the consumption of the same, if any, has to be strictly in moderation, and is best avoided. Smoking is to be avoided as well. Again, red meat, butter, refined grains, sweets, sugary drinks including carbonated beverages and other high calorie foods etc all, if any, are to be taken sparingly or are best avoided too. Limiting dosage/ duration of hormone therapy, if any, especially to counteract post menopausal symptoms and also avoiding exposure to radiation and environmental pollution can help reduce the risks of breast cancer. Apart from the above-mentioned, for high risk cases, a prophylactic oophorectomy, prophylactic radical mastectomy, long term hormone therapy etc all can help reduce the chances/ risks of developing breast cancer significantly. Breastfeeding is known to confer protection against breast cancer risk too.