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Dr. M.D. Sharma

Nephrologist, Delhi

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Dr. M.D. Sharma Nephrologist, Delhi
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I believe in health care that is based on a personal commitment to meet patient needs with compassion and care....more
I believe in health care that is based on a personal commitment to meet patient needs with compassion and care.
More about Dr. M.D. Sharma
Dr. M.D. Sharma is an experienced Nephrologist in Karkardooma, Delhi. You can meet Dr. M.D. Sharma personally at Deepak Memorial Hospital in Karkardooma, Delhi. Save your time and book an appointment online with Dr. M.D. Sharma on has an excellent community of Nephrologists in India. You will find Nephrologists with more than 33 years of experience on You can find Nephrologists online in Delhi and from across India. View the profile of medical specialists and their reviews from other patients to make an informed decision.


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Nephrotic Syndrome: Causes and Treatment

MBBS, MD - Medicine, DM - Nephrology
Nephrologist, Delhi
Nephrotic Syndrome: Causes and Treatment

Glomerulonephritis is a disease that is caused due to inflammation of the small filters that are present within the kidneys or glomeruli. Glomeruli eliminate the excess waste, electrolytes and fluids from the blood, discharged through urine. A glomerular disease can be either acute or chronic. If the condition arises without a combination of any other disease, it is termed as primary glomerulonephritis. Secondary glomerulonephritis is characterized by diabetes or lupus (an auto-immune disorder) being at the root of the disease. Prolonged or severe inflammation can take a toll on the kidneys.


Nephrotic syndrome can be primary, being a disease specific to the kidneys, or it can be secondary, being a renal manifestation of a systemic general illness. In all cases, injury to glomeruli is an essential feature. Kidney diseases that affect tubules and interstitium, such as interstitial nephritis, will not cause nephrotic syndrome.

Primary causes of nephrotic syndrome include the following, in approximate order of frequency:

  1. Minimal­-change nephropathy

  2. Focal glomerulosclerosis

  3. Membranous nephropathy

  4. Hereditary nephropathies

Secondary causes include the following, again in order of approximate frequency:

  1. Diabetes mellitus

  2. Lupus erythematosus

  3. Viral infections (e.g., hepatitis B, hepatitis C, human immunodeficiency virus [HIV] )

  4. Amyloidosis and paraproteinemias

  5. Preeclampsia

  6. Allo-antibodies from enzyme replacement therapy

Nephrotic-­range proteinuria may occur in other kidney diseases, such as IgA nephropathy. In that common glomerular disease, one-third of patients may have nephrotic-­range proteinuria.

Nephrotic syndrome may occur in persons with sickle cell disease and evolve to renal failure. From a therapeutic perspective, nephrotic syndrome may be classified as steroid sensitive, steroid resistant, steroid dependent, or frequently relapsing.


  1. Whether one is suffering from acute or chronic nephrotic glomerular , with symptoms moderate or severe, the treatment lies in treating high blood pressure and other underlying conditions of the disease.

  2. Water pills help control sweating, thus increasing the fluid flushed from the kidneys.

  3. Statins reduce cholesterol level.

  4. Blood thinners such as anticoagulants lower the risk of blood clots.

  5. Corticosteroids regulate the immune system and ease the inflammation that results from kidney disorders.

  6. Incorporating certain lifestyle changes such as opting for lean proteins, cutting on the intake of fat in the diet and consuming lesser amounts of salt can treat inflammation and swelling.

  7. For kidney failure, dialysis can come to the aid in eliminating excess fluids and regulating hypertension. If you wish to discuss about any specific problem, you can consult a Nephrologist.

3192 people found this helpful

I was suffering from high sugar may be for a long time near to 440 diagnosed as diabetic type 2 latter and urine sugar +++ which I have controlled now since for last 2 month after diagnosis. During that period I have some infection in my private parts. please tell me what I do now, it also feels I have foam in my urine.

General Physician, Mumbai
I was suffering from high sugar may be for a long time near to 440 diagnosed as diabetic type 2 latter and urine suga...
In a known case of diabetic we need to control sugar levels with medication, aerobic exercise and following a diabetic diet and we have to examine the private part for pinpointing the cause of infection either fungal or bacterial and take treatment accordingly.
1 person found this helpful
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I am having frequent urination. Uncontrolled urination. urge of urination. Sensation in urethra with mild pain. Taking Alpha-Blocker.

Homeopath, Sindhudurg
I am having frequent urination. Uncontrolled urination. urge of urination. Sensation in urethra with mild pain. Takin...
Homoeopathic treatment - Sabal serrulata Q 15 drops - 3 times Thuja 1m - just one ?dose 4 pills and inform after 15 days for further treatment
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How To Get Rid Of Kidney Stones?

MBBS, M.S. (General Surgery), MBA (Healthcare), M.Ch - Urology/Genito-Urinary Surgery
Urologist, Gurgaon
How To Get Rid Of Kidney Stones?

A kidney stone may not be as big as the stones in your garden, but can be quite a pain. Kidney stones are actually mineral crystals that are usually a combination of calcium and phosphates. The size of a kidney stone ranges from the size of a sugar crystal to a ping pong ball. While some kidney stones pass out of the body along with urine, others can block the ureter and become painful. 

In addition to being painful, a kidney stone can cause permanent damage to your kidneys. Since large kidney stones are usually painful, they rarely go undiagnosed. However, if a kidney stone is left untreated, it could cause the kidney to atrophy and lower the functionality of the kidney. Kidney stones that are related to an infection can also lead to chronic urinary tract infections and damage the kidney through scarring and inflammation. This could eventually lead to kidney failure.
Not all kidney stones need to be treated with surgery. If the kidney stone is very small, your doctor may prescribe plenty of water and medication to treat the pain. With plenty of water, you should be able to pass the stone in your urine. Ideally, you should take plenty of rest until the stone is passed. 

Larger kidney stones may need you to be hospitalized for treatment. These are:

  • Extracorporeal shock wave lithotripsy (ESWL): To begin this of treatment, a painkiller is administered. Ultrasonic waves are used to determine the location of the kidney stone. Shock waves are then passed through the kidney stone to break it into smaller pieces, which can then pass out of the body through urine.
  • Ureteroscopy: This is also called retrograde intrarenal surgery and is performed when the kidney stone is stuck in the ureter. A ureteroscope is passed through the urethra and bladder into the ureter. Laser energy may then be used to break the stone into smaller pieces to unblock the ureter. 
  • Percutaneous nephrolithotomy (PCNL): This surgery is performed under general anesthesia.  It involves a small incision being made in the back and a nephroscope passed into the kidney through it. Laser or pneumatic energy is then used to break up the stone into smaller pieces and pull them out. 
  • Open surgery: Open surgery is performed only in the case of an abnormally large stone or abnormal anatomy of the person. An incision is made in the back that allows the doctor to access the kidney and manually remove the stone. In case you have a concern or query you can always consult an expert & get answers to your questions!
2038 people found this helpful

How can be brought to normal Creatinine 2.6 .is diabetic .is taking glimy 2.has hypertension. Taking aztor 10. Urine albumin is 2.

MBBS, CCEBDM, Diploma in Diabetology, Diploma in Clinical Nutrition & Dietetics, Cetificate Course In Thyroid Disorders Management (CCMTD)
Endocrinologist, Hubli-Dharwad
How can be brought to normal Creatinine 2.6 .is diabetic .is taking glimy 2.has hypertension. Taking aztor 10. Urine ...
Hello, Thanks for the query. When a person has long standing diabetes, it does affect kidney function, even when it is very well controlled. But if the blood glucose levels are not in proper check then damage to kidney is much earlier and more. Since you have not mentioned any thing about blood glucose levels and HbA1c%, it is difficult to know. Further if the patient also has hypertension, then unless that is well controlled (120 to 130 /70 to 80 mm Hg), there can be more stress on kidney. To reduce creatinine, first and foremost is to achieve a strict blood glucose control with FBG :<100 mg, PP :160 to 170 mg & HbA1c% <7. Plus if patient is not on either ACE inhibitor or ARB, then it should be started. Secondly protein intake should be restricted to about 0.6 g / kg body weight per day. Plus should do less vigorous physical activity and drink enough liquids. Thanks.
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I've observed wen I control my pee for longer time it loses pressure while peeing.Is it a negative sign.Pls help.

Fellowship of the Royal College of Surgeons (FRCS), MS - Urology, MBBS
Urologist, Ahmedabad
Dear , It is normal that when you retain urine for a long time urinary bladder gets over distended and when it stretches beyond a critical level bladder muscle losses power to contract normally and contracts feebly so forces is less. It is not a negative sign but you should not be doing so.If bladder gets overdistended the you may develop retention of urine. Dr. Kiran Mehta.
1 person found this helpful
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What Can Possibly Cause Blood In Urine?

MBBS, MS - General Surgery, M.Ch - Urology
Urologist, Bangalore
What Can Possibly Cause Blood In Urine?

Blood in urine, medically known as Hematuria is not usually a cause of concern, but it can translate into an adverse condition if left unevaluated. The kidneys and other structures in the urinary tracts such as urethra (tube connecting the bladder to the outer part of the body); bladder (that stores the urine) and ureters (tube joining the bladder to the kidney) are the sources of blood flow to the urine. Hematuria can be accompanied by symptoms such as discharge of tea-colored, brownish-red or pink colored urine due to the presence of red blood cells, traces of which can only be detected under the microscope.

Underlying causes behind this disorder might be

  1. Urinary tract infection is where the bacteria enter the body through the urethra and begin to proliferate in the bladder.
  2. Kidney infections (pyelonephritis) is when bacteria infiltrate into the kidneys from the bloodstream or travel up from the uterus to the kidneys.
  3. A kidney or a bladder stone is marked by the minerals in the concentrated urine precipitating out and molding into crystals that deposit on the bladder or kidney walls.
  4. Enlarged prostate is a condition in which the prostate gland, that is situated just below the bladder surrounding the upper part of the urethra, starts growing as males head towards their middle age.
  5. Kidney disease such as glomerulonephritis causes swelling of the kidneys, thus disrupting the filtering system.
  6. Bladder, kidney and prostate cancer are also possible causes.
  7. Hereditary disorders such as sickle cell anemia (a hereditary disease of the red blood cells in the hemoglobin) can also pose as a cause behind this disorder.
  8. Kidney injury as a result of heavy blows, accidents or injuries sustained while playing a spot can also contribute to this condition.
  9. Medications such as penicillin or the anti-cancer drug ‘cyclophosphamide’
  10. Strenuous physical exercises like intense workout or running may also result in Hematuria.

There is no fixed cure for Hematuria; instead the doctor would work on treating the repressed conditions behind the symptoms, such as prescribing antibiotics to heal the urinary tract infection or a medicine to shrink and normalize the enlarged prostate or administer a shock wave therapy to destroy the kidney or bladder stones

In case you have a concern or query you can always consult an expert & get answers to your questions!

3326 people found this helpful

I'm suffering from kidney stone left kidney stone is 3.8 mm and right kidney stone is 4.8 mm so how can it b helpful to me should I take medicine or any exercise or should I go for operation.

DHMS (Diploma in Homeopathic Medicine and Surgery)
Homeopath, Delhi
I'm suffering from kidney stone left kidney stone is 3.8 mm and right kidney stone is 4.8 mm so how can it b helpful ...
kidney stones can be cured with medicines which are combination of herbal and homeo. There will no such need to undergo surgery or operations. I will suggest you to avoid surgery there is no need of it. You need to take medicines that can help in removing them naturally such as our medicines combination of herbal and homeo that will help in removing stones. Kidney gets diseased due to an unhealthy diet and lifestyle. A kidney stone is a hard mass developed from crystals that separate from the urine within the urinary tract. Normally, urine contains chemicals that prevent or inhibit the crystals from forming.If the crystals remain tiny enough, they will travel through the urinary tract and pass out of the body in the urine without being noticed. You can connect with me and I will provide you with treatment by which you will be getting cured with kidney stones naturally. The medicines are combination of herbal and homeopathic only.
1 person found this helpful
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1. Initially I get erection (that too not satisfactory) but I loose it as I get ready for intercourse, after that I find it hard to get an erection and maintain it. Sometimes when I get full erection I loose it gradually as soon as I perform intercourse 2. I get to climax within 0-10 seconds Due to this I am not able to enjoy my married life, I am married since 3 years Other problems - I have acute sinusitis, digestion problem and anxiety / depression related issues, and frequent urination problem. Out of this currently I am undergoing unani treatment for sinus and frequent urination.

BAMS, MD Ayurveda
Sexologist, Navi Mumbai
1. Initially I get erection (that too not satisfactory) but I loose it as I get ready for intercourse, after that I f...
One of the simplest home remedies Saffron is a mild aphrodisiac 1. Soak 10 almonds in water overnight 2. Peel off the skin and crush them the next morning 3. Take 1 cup hot cow's milk 4. Add the crushed almonds 5. Add a pinch of ginger powder 6. Add a pinch of cardamom powder 7. Add a pinch of saffron 8. Mix well 9. Drink this every morning Causes: • Anxiety • Incorrect diet • Unhealthy lifestyle This remedy will be helpful.
2 people found this helpful

I am 28 years old male. I have been suffering from excess urine call and some time unable to discharge but felt intense to discharge since 2005. I have been treated by Dr. who was the urologist of medical college lucknow but not taking any positive response.

M.B.B.S., D.M.C.H.
General Physician, Alwar
When you are not able to pass urine, sit down in ukru position, relax your perineum like while passing stools, try to pass urine without exerting pressure. You can take analgesic with tizanidine twice daily. Avoid constipation. Go for walk both times daily.
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