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PCOS is an abbreviation for Polycystic Ovarian Syndrome. It is a problem that is caused in women when their hormones are out of balance. It affects menstrual periods and can even hinder conception when aggravated to an advanced stage. Many women having PCOS develop small cysts on their ovaries. These cysts might not be harmful, but they lead to hormonal imbalances.
Common symptoms include:
- Gain of weight or Weight loss problems
- Excess hair on body and face
- Irregularities in periods
- Fertility problems
It is possible for most women with PCOS who fail to attain pregnancy easily to use other treatments to get pregnant. Using In vitro fertilization (IVF) is one such mode of treatment. The procedure is helpful if done within the age of forty. You should undergo IVF only in a high quality clinic under the supervision of an experienced doctor.
There is a considerable amount of risk of having a higher order multiple pregnancy due to treatment of PCOS infertility using injectable gonadotrophins. Recent developments have allowed the patients to maintain high rates of pregnancy while simultaneously controlling the risk of multiple pregnancy. A variant of the standard IVF treatment known as Blastocyst embryo transfer is useful in the control of multiple birth rates. Generally, success rates for IVF treatment in cases where infertility is caused due to PCOS is quite high.
IVF Protocols for PCOS
There are two simulation protocols that are commonly used with PCOS:
- Ganirelix with Lupron trigger protocol: Used to avoid ovarian hyperstimulation syndrome.
- PCOS down-regulation protocol
This protocol combines:
- Oral Contraceptive Pills
A calendar is followed for the down regulation protocol for PCOS. Before starting with Lupron, a dosage ( 500 mg, 3 times a day) of metformin is followed daily. After this, oral contraceptive pills are prescribed for around 21 days. Lupron coincides with the last 3 pills of birth control.
Lupron is a subcutaneous injection of a medicine that is taken once daily. Simulation of the ovaries is initiated after 6 or 7 days without using pills. It is very important with polycystic ovary that the dose of FSH hormone is properly controlled and that the ovarian response is cautiously monitored. Over response to the treatment can cause ovarian hyperstimulation syndrome. This should be avoided.