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Dr. Geetha

Gynaecologist, Chennai

Dr. Geetha Gynaecologist, Chennai
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Our team includes experienced and caring professionals who share the belief that our care should be comprehensive and courteous - responding fully to your individual needs and preferences....more
Our team includes experienced and caring professionals who share the belief that our care should be comprehensive and courteous - responding fully to your individual needs and preferences.
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Dr. Geetha is one of the best Gynaecologists in Thiruvanmiyur, Chennai. You can consult Dr. Geetha at Starlight Hospitals Pvt Ltd. in Thiruvanmiyur, Chennai. Book an appointment online with Dr. Geetha on Lybrate.com.

Lybrate.com has an excellent community of Gynaecologists in India. You will find Gynaecologists with more than 28 years of experience on Lybrate.com. You can find Gynaecologists online in Chennai and from across India. View the profile of medical specialists and their reviews from other patients to make an informed decision.

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Starlight Hospitals Pvt Ltd.

Old No. 3, New No. 11, North Mada Street, Thiruvanmiyur. Landmark: Near Bus Terminal, ChennaiChennai Get Directions
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Breast reconstruction after breast cancer treatment

MCh - Plastic and Reconstructive Surgery, MS - General Surgery, MBBS
Cosmetic/Plastic Surgeon, Hyderabad
Breast reconstruction after breast cancer treatment

Breast cancer is devastating for any woman more so if she is in the prime age.

The usual process suspicion followed by an examination, investigation, confirmation and then treatment depending on the stage of the disease and follow-up.

On confirmation of breast cancer, either the lady undergoes partial mastectomy, nipple sparing mastectomy, total mastectomy or radical mastectomy. This is followed up by Chemotherapy, radiation therapy or both for a period of time which is thought to be the end of treatment.

This leaves the patient traumatized with the loss of an important part of her body with the ill effects of radiation which also leads to severe burning sensation and pain in the area of radiation.

Breast Reconstruction plays an important role in completing the treatment and making the woman a woman again physically and psychologically.

There are various methods of reconstruction by way of transferring tissue from different parts of the body in stages and at the same time resizing the opposite breast to achieve symmetry.

Fat transfer technique is an advanced method of treatment which not only helps rebuild the lost structure but also improves the blood circulation to the affected part, reverses the ill effects of radiation and it also improves the surgical scar while not adding to more scars in the body. This is accompanied with improving body contour from where the excess unwanted body fat is removed which is transferred to the creation of the new breast.

Top 5 Lifestyle Changes To Improve Your Cholesterol!

M.Sc. in Dietetics and Food Service Management , Post Graduate Diploma In Computer Application, P.G.Diploma in Clinical Nutrition & Dietetics , B.Sc.Clinical Nutrition & Dietetics
Dietitian/Nutritionist, Mumbai
Top 5 Lifestyle Changes To Improve Your Cholesterol!

1. Eat heart-healthy foods

Even if you have years of unhealthy eating under your belt, making a few changes in your diet can reduce cholesterol and improve your heart health.

Choose healthier fats. Saturated fats, found primarily in red meat and dairy products, raise your total cholesterol and low-density lipoprotein (ldl) cholesterol, the" bad" cholesterol. As a rule, you should get less than 7 percent of your daily calories from saturated fat. Choose leaner cuts of meat, low-fat dairy and monounsaturated fats — found in olive and canola oils — for healthier options.
Eliminate trans fats. Trans fats affect cholesterol levels by increasing the" bad" cholesterol and lowering the" good" cholesterol. This bad combination increases the risk of heart attacks. Trans fats can be found in fried foods and many commercial products, such as cookies, crackers and snack cakes. But don't rely on packages that are labeled" trans fat-free" in the united states, if a food contains less than 0.5 grams of trans fat in a serving, it can be labeled" trans fat-free"

Even small amounts of trans fat can add up if you eat foods that contain small amounts of trans fat. Read the ingredient list, and avoid foods with partially hydrogenated oils.

Eat foods rich in omega-3 fatty acids. Omega-3 fatty acids don't affect ldl cholesterol. They have other heart benefits, such as helping to increase high-density lipoprotein (hdl, or" good") cholesterol, reducing your triglycerides, a type of fat in your blood, and reducing blood pressure. Some types of fish — such as salmon, mackerel and herring — are rich in omega-3 fatty acids. Other good sources of omega-3 fatty acids include walnuts, almonds and ground flaxseeds.

Increase soluble fiber. There are two types of fiber — soluble and insoluble. Both have heart-health benefits, but soluble fiber also helps lower your ldl levels. You can add soluble fiber to your diet by eating oats and oat bran, fruits, beans, lentils, and vegetables.
Add whey protein. Whey protein is one of two proteins in dairy products — the other is casein. Whey protein may account for many of the health benefits attributed to dairy. Studies have shown that whey protein given as a supplement lowers both ldl and total cholesterol.

You can find whey protein powders in health food stores and some grocery stores. Follow the package directions for how to use them.

2. Exercise on most days of the week and increase your physical activity

Exercise can improve cholesterol. Moderate physical activity can help raise high-density lipoprotein (hdl) cholesterol, the" good" cholesterol. 

Adding physical activity, even in 10-minute intervals several times a day, can help you begin to lose weight. Just be sure that you can keep up the changes you decide to make. Consider:

  • Taking a brisk daily walk during your lunch hour
  • Riding your bike to work
  • Swimming laps
  • Playing a favorite sport
  • To stay motivated, find an exercise buddy or join an exercise group. And remember, any activity is helpful. Even taking the stairs instead of the elevator or doing a few situps while watching television can make a difference.

3. Quit smoking

If you smoke, stop. Quitting might improve your hdl cholesterol level. And the benefits don't end there.

Within 20 minutes of quitting, your blood pressure and heart rate decrease. Within one year, your risk of heart disease is half that of a smoker. Within 15 years, your risk of heart disease is similar to someone who never smoked.

4. Lose weight

Carrying even a few extra pounds contributes to high cholesterol. Losing as little as 5 to 10 percent of your weight can improve cholesterol levels.

Start by evaluating your eating habits and daily routine. If you eat when you're bored or frustrated, take a walk instead. If you pick up fast food for lunch every day, pack something healthier from home. For snacks, munch on carrot sticks or air-popped popcorn instead of potato chips. Don't eat mindlessly.

And look for ways to incorporate more activity into your daily routine, such as using the stairs instead of taking the elevator or parking farther from your office.

5. Drink alcohol only in moderation

Moderate use of alcohol has been linked with higher levels of hdl cholesterol — but the benefits aren't strong enough to recommend alcohol for anyone who doesn't already drink. If you drink alcohol, do so in moderation. For healthy adults, that means up to one drink a day for women of all ages and men older than age 65, and up to two drinks a day for men age 65 and younger.

Too much alcohol can lead to serious health problems, including high blood pressure, heart failure and stroke.

14 people found this helpful

I am 25 years old married woman. It has been 1 months since my marriage. Still I have not got my periods. I checked for pregnancy using home test kit for 3 times. The result is negative. Can you pls suggest or help me to identify approximately what the problem can be?

MD - Obstetrtics & Gynaecology
Gynaecologist, Mumbai
I am 25 years old married woman. It has been 1 months since my marriage. Still I have not got my periods. I checked f...
Menses can be missed either because of hormonal changes or even stress or even if you have put on some weight in recent times then also menses can be missed. All these problems are temporary and menses will come on its own. You can wait for another 30 days before you can take tablet deviry to get menses. In the meantime, keep repeating urine pregnancy test every week till you get your menses.
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Suppose I cum last night and went to toilet nxt morning several time. At evening my little precum touches on my partners vagina then will she get pregnant.

MD - Obstetrtics & Gynaecology
Gynaecologist, Mumbai
Suppose I cum last night and went to toilet nxt morning several time. At evening my little precum touches on my partn...
If the precum is deposited inside the vagina she can get pregnant. As you will not be sure of this so please give her ipill asap.
2 people found this helpful
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Pregnancy

General Physician, Kolkata
Pregnancy
Avoid drinking too much of water in the first trimester of pregnancy.
Have plenty of fruits containing iron like pomegranate.

I had unprotected sex with my girlfriend 2 days after her periods was over, as she told me that 10 days after period are safe to have unprotected sex. Is that true?

MBBS, MS - Obstetrics and Gynaecology
Gynaecologist, Nagpur
I had unprotected sex with my girlfriend 2 days after her periods was over, as she told me that 10 days after period ...
Dear lybrate-user, if she has regular cycles of 28 days and periods last for 4 days or so then till 8th day of 1st day of periods it is safe period. But remember that for once its ok but this method has failure rate of upto 20% and not a strong contraceptive
2 people found this helpful
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I am currently pregnant and getting cold very frequently. Is having citrozen suggestible during pregnancy? And how frequently can I have these tablets as I am getting cold at least once a week? Thanks in advance for your reply.

BHMS
Homeopath, Nagpur
I am currently pregnant and getting cold very frequently. Is having citrozen suggestible during pregnancy? And how fr...
Unless you have fever or any other sign of infection, you should avoid any medicine unless prescribed by your obstetrician. You have not written about the length of pregnancy, because in 1st trimester you must not take any medicine except by prescription. In later trimesters some medicines can be given guardedly. Cold is not something to be worried for. Cetrizine is an antihistamine drug and is not indicated during pregnancy unless benefits outweigh risks.
2 people found this helpful
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I was having intercourse with my girlfriend with condom but after sperm, I took off my condom and put back my penis into her then suddenly took off it but didn't intercourse without condom, my penis head was having little sperm. will she get pregnant?

DNB (Obstetrics and Gynecology), PGDHHM, MBBS
Gynaecologist, Delhi
I was having intercourse with my girlfriend with condom but after sperm, I took off my condom and put back my penis i...
There can be possibility of sperm entering vagina and she may get pregnant. It is advised to ecp immediately after such contact.
2 people found this helpful
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Periodontal Disease - 7 Ways You Can Manage and Prevent them

MDS , BDS
Dentist, Delhi
Periodontal Disease - 7 Ways You Can Manage and Prevent them

The gums are also called the periodontium which means perio for around and dontium for tooth as the gums are literally present "around the tooth."  There is a softer mucosal portion that runs along the tooth in a curved manner and a stronger fibrous portion that connects the tooth to the jaw bone.  Together, they provide the structural support for the tooth to be held in place. In addition they also have an aesthetic value with the healthy pink color.

The mouth has the largest number of bacteria in the body, which act on the food debris that is present on the tooth and the gums. This causes infection in both the gums and the tooth. 

Types: Periodontal disease can be localized or general.

  1. Localized disease happens when a tooth is not accessible for thorough cleaning.  The inside surface of lower incisors and outer surfaces of the upper last molars are common areas of localized periodontal disease. 
  2. Generalized periodontal disease can be due to conditions like pregnancy, puberty, diabetes problem where gums around all the teeth are affected.

Symptoms: In both the cases, the following symptoms ensue: 

  1. The gums are of a healthy pink color and if they turn darker hue of pink
  2. Swollen and/or painful gums
  3. Spontaneous bleeding: This may be localized or generalized 
  4. Chronic bad breath: Due to food accumulation in the infected gums
  5. If it continues to form an abscess, pressure on the gums can produce pus
  6. Bad taste in the mouth (arising from pus in the gums)
  7. Gingival recession, producing an effect of having longer tooth 
  8. Dentin is exposed leading sensitivity to hot or cold foods
  9. Loosening of the tooth
  10. Painful chewing, as it puts pressure on the inflamed periodontium
  11. Dentist will identify what are called pockets, which is an indication of severity - the deeper the pockets, the severe the disease.

Management and Prevention: Gum disease is very easy to identify and can be completely cured.

  1. Regular brushing and flossing can help maintain regular oral hygiene 
  2. With each brushing session, plain finger massage of the gums improves blood circulation and their overall health
  3. Regular use of mouth rinse is a good way to improve gum health
  4. Regular visits to the dentist can help keep a check on the health of the teeth and the gums - early identification of disease and early treatment
  5. Once it has set in, deep scaling followed by root planing may be required to thoroughly clear out the infection
  6. More surgical options like gingival grafts, flap surgery, bone grafting in case of severe bone loss may be required. 
  7. Management of conditions like diabetes

The best way to avoid periodontal disease is to know its symptoms, follow oral hygiene practices, and consult a dentist regularly.

3403 people found this helpful

I am 39 weeks pregnant. From today I am having contractions with backache in every 3-5 mins and in the evening started bleeding. But baby did not dropped yet. What to do? Now how much I am near to the true active labour? Expected delivery time?

MD - Obstetrtics & Gynaecology
Gynaecologist, Mumbai
I am 39 weeks pregnant. From today I am having contractions with backache in every 3-5 mins and in the evening starte...
Pains every 3-5 min is a part of active labor and you already have blood discharge menans you r in labor. You have to report to the hospital asap for the delivery.
1 person found this helpful
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STDs will spread through lip-lock kissing or it will spread through saliva? Some of my friends told me that it will spread, and some told it will not spread.

MD - Homeopathy, Masters Degree of Homoeopathy
Homeopath, Mumbai
std can spread through exchange of body fluids so therotically it can spread but practically chances are less
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I am 25 year old. I was taking homeopathy medicines for pcod problem in the last two years. My periods got regularised and my acne too got cured yet my hair thinning is still there from front .it has got very thin. I dnt have any thyroid problem too. I eat healthy diet and exercise too. What is the reason? Please suggest for my hair problem.

Bachelor of Ayurveda, Medicine and Surgery (BAMS)
Ayurveda, Fazilka
I am 25 year old. I was taking homeopathy medicines for pcod problem in the last two years. My periods got regularise...
Take balanced diet green vegetables fruits milk cheese avoid oily fried and fast foods Teak kishmish 32 no. Khajoor 2 no. Anjeer 2 no. Soak in one glass water at night and take in morning empty stomach for four weeks safe ayurvedic treatment available consult me through Lybrate.
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I am 9 month pregnant, in my sonography report-" two umbilical cord loop is seen around foetal neck. Please suggest possibilities- easily normal delivery or operation.

DNB (Obstetrics and Gynecology), PGDHHM, MBBS
Gynaecologist, Delhi
I am 9 month pregnant, in my sonography report-" two umbilical cord loop is seen around foetal neck. Please suggest p...
Normal delivery is possible only if fetal heart rate remains normal and there is progress and decent during labor pains. C-section can be done in case of emergency or by choice.
1 person found this helpful
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What should I have to do to get rid of itching (whole body parts) in my last month of pregnancy?

MBBS
General Physician,
What should I have to do to get rid of itching (whole body parts) in my last month of pregnancy?
it is natural to have itching in last month some moisturizers and few medicines will solve your problem
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I am 20 year old girl suffering from pcod for the past 2 year I have taken treatment but there is no effect either ayurvedic treatment is better result?

Diploma in Obstetrics & Gynaecology, MBBS, MD - Community Medicine
Gynaecologist, Lucknow
Hello, pcos is a lifestyle disease resulting in hormonal imbalance. Your weight is on higher side. You should modify your lifestyle and diet. Reduce your weight about 10%. Drink plenty of water and liquids and do exercise daily.
3 people found this helpful
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Vajikarana Therapy for Sexual Disorders in Ayurveda

Bachelor of Ayurveda, Medicine and Surgery (BAMS)
Ayurveda, Ambala
Vajikarana Therapy for Sexual Disorders in Ayurveda

Sexuality has fascinated people in all walks of life from antiquity to the present. Healthy sexual functioning plays a fundamental role in maintaining harmony and happiness in married life. It is the most essential to fill the procreational, recreational and relational aspects of life.

It provides a means to express love, which is the basis for all kinds of creative activities. The absence of which hinders the marital relationship that leaves the frustration, at some point ends in divorce and causes inefficiency in performing routine duties.

Infertility is defined as failure to achieve a pregnancy after a year of unprotected regular intercourse with the same partner. Infertility also affects men and women. Living a healthy lifestyle is important for fertility. Lifestyle factors can affect a man’s fertility, and many of these factors are things that a man can control. Leading a healthy lifestyle improves not only the possibilities of conceiving but also improves overall health.

Ayurveda, the science of life, prevention and longevity, is the oldest and most complete holistic medical system available in the world. Its basic principles can be found in the Hindu scriptures called the Vedas, the ancient Indian books of wisdom written more than 5,000 years ago.

Ayurveda uses the principles inherent in nature to help preserve the health of a person by keeping the body, mind and spirit of the person in perfect balance with nature.

Ayurveda has developed a special branch to deal with the problems of infertility known as Vajikarana, which means: make us potent as a vaji “horse”. The name derives from the fact that horses have always been a symbol of virility in ancient cultures.

Ayurveda states that reproductive health depends on the health of shukra and atharv dhatu, or reproductive tissue, in both men and women respectively. In women tissue atharv produces the ovum as part of the monthly cycle, and men produce semen.

The quality of the breeding juices is directly related to the quality of the other tissues. The physical body consists of seven tissues (dhatu): plasma, blood, muscles, fat, bones, nerves and finally the reproductive tissue. The food we eat is metabolized in the digestive system and transformed – through agni, or fire – into nutrients for our body. These nutrients are what will make up the first tissue, plasma.

From there, the other tissues are being form one by one using as part of the subsequent tissue as the base material. The height of this process is reached when part of the reproductive tissue is transformed into an eighth tissue, subtle in nature, known as ojas (an essence that gives us immunity, brilliance, strength, splendor and vitality)

Infertility can often be associated with deficiency in the correct production of body tissues, poor quality of agni, as well as the presence of toxins due to inadequate diet and lifestyle.

There are two types of foods and herbs that help improve shukra dhatu, and thus help improve fertility. Some are called bringhana, and these foods strengthen the seven dhatus. The second type is called vrishya and these foods and herbs are for the shukra dhatu in particular. Bringhana foods are fresh organic fruits and vegetables, whole grains, milk proteins, soaked almonds and walnuts, natural sweets, juicy fruits like mangos and dried fruits like figs. Vrishya foods are asparagus, broccoli, happy cow’s milk and spices like cumin seeds and coriander, shatavari, kapikachu and kalamusli.

Types of vajikarana

Ayurveda considers all substances that enhance the sexual activity as vajikarana dravyas and may include herbs, ornaments, gold, silver, pearls, precious stones etc. Vajikarana dravyas include the following:

Semen enhancing like milk, ghee, gokshura, shatavari, yashtimadhu etc. Semen purifying like kushtha, sugar cane, bayberry etc. Promoting fertilization capacity in semen like brahmi, shatavari, katuka, guduchi etc. Libido increasing like akarakarabha, saffron, clove, garlic, pippali etc. Premature ejaculation preventing like nutmeg, ashwagandha, chandan, jatamansi etc.

Benefits of vajikarana therapy:

Increases the time span of erections. Cure erectile dysfunction. Prevents premature ejaculation. Stimulates man for sexual acts to satisfy females without getting tire. Transforms lean and impotent men into powerful and vigorous. Facilitates in procreation of healthy off springs. Increases sexual energy and strength like a horse. Increases will power, intellect and memory in addition to promoting a healthy body.

1 person found this helpful

While having sexual contact. While we do not use condom. The sperm while enter the body it will make pregnancy. So here is my question. Any medicine is their to kill sperm 100% with out using condoms.

MBBS
General Physician, Faridabad
While having sexual contact. While we do not use condom. The sperm while enter the body it will make pregnancy. So he...
Spermicides come in several different forms: cream, gel, foam, film, and suppositories. Most spermicides contain nonoxynol-9, a chemical that kills sperm. Spermicides can be used alone but are more effective when used with another method of birth control, such as a condom or diaphragm.
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Hi Sir as I said about my wife age 32 year weight 75 kg is suffering from irregular period problem with scanty bleeding continues to four five days is also suffering from migraine problem. Can u please suggest me medical advice with period of treatment. Thank you sir

DHMS (Diploma in Homeopathic Medicine and Surgery)
Homeopath, Ludhiana
I will advise you to go for homoeopathic treatment for the problem. The treatment can vary from 3-5 monthss depending on the response.
1 person found this helpful
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While having sex my wife's periods started, and we did not knew that, please tell me if there's any chance of infection as we didn't used any precaution at that time as she's absolutely healthy.

Fellowship in Comprehensive Ophthalmology, DOMS
Ophthalmologist, Sangrur
Hello There is risk of transmission of HIV if partner is infected with HIV There is risk of bacterial infections also It is recommended to use condoms during sexual intercourse during periods Please don't worry...But be aware for next time
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First Vaccine Again Dengue

M.B.B.S,C.C.A,D.C.A,AASECT,FPA,AAD,M.I.M.S
General Physician, Gorakhpur
First Vaccine Again Dengue

Dengvaxia - First vaccine against dengue:

Dengvaxia is a vaccine used to help protect adult or children against dengue disease caused by dengue virus serotypes 1, 2, 3 and 4. Dengvaxia is given to adults, adolescents and children 9 through 45 years of age living in endemic areas.

 

Read more:-

Dengue symptoms and what to do if you think you have denguedengue fever - remedies using papaya leaf juice

 

Full prescribing info - dengvaxia

Contents

Dengue tetravalent vaccine (live, attenuated).

Indications / uses

Dengvaxia is a vaccine used to help protect adult or children against dengue disease caused by dengue virus serotypes 1, 2, 3 and 4. Dengvaxia is given to adults, adolescents and children 9 through 45 years of age living in endemic areas.

Dosage / direction for use

The patient will receive 3 injections of 0.5 ml each at 6-month intervals.

The first injection will occur at the chosen or scheduled date; the second injection, 6 months after the first injection; and the third injection, 6 months after the second injection. Dengvaxia should be used according to the local vaccination schedule.

If the patient forgot an injection of dengvaxia: if the patient missed a scheduled injection, the physician will decide when to give the missed injection.

It is important that the patient follows the instructions of the physician, pharmacist or nurse regarding return visits for the follow-up injection. If the patient forgets or is not able to go back to the physician, pharmacist or nurse at the scheduled time, ask the physician, pharmacist or nurse for advice.

Administration: dengvaxia is given by the physician or nurse as an injection underneath the skin (subcutaneous route) in the upper arm.

Contraindications

Do not use dengvaxia if the patient is allergic (hypertensive) to the active substances or any of the other ingredients of dengvaxia listed in description (see description); has developed an allergic reaction after prior administration of dengvaxia. Signs of an allergic reaction may include an itchy rash, shortness of breath and swelling of the face and tongue; is suffering from a disease with mild to high fever or acute disease. In this case, the physician will postpone the administration of dengvaxia until the patient has recovered; has a weakened immune system, for example due to a genetic defect, hiv infection or therapies that affect the immune system (for example, high-dose corticosteroids or chemotherapy); is pregnant; is breastfeeding.

Use in pregnancy lactation: Dengvaxia must not be given to pregnant or breastfeeding women.

If the patient is of child-bearing stage, the patient should take the necessary precautions to avoid pregnancy for 1 month following administration of dengvaxia; is pregnant or breastfeeding, the patient thinks may be pregnant or is planning to have a baby, ask the physician, pharmacist or nurse for advice before receiving dengvaxia.

Special precautions

Inform the physician, pharmacist or nurse before receiving dengvaxia if the patient is taking an immunosuppressive treatment (prednisone or equivalent to 20 mg or 2 mg/kg for 2 weeks or more). The physician will postpone administration of dengvaxia until 4 weeks after the treatment is discontinued; has experienced any health problems after prior administration of any vaccines. The physician will carefully consider the risks and benefits of vaccination.

As with all vaccines, dengvaxia may not protect 100% of persons who have been vaccinated. Vaccination with dengvaxia is not a substitute for protection against mosquito bites. The patient should take appropriate precautions to prevent mosquito bites, including the use of repellents, adequate clothing, and mosquito nets.

Fainting, sometimes accompanied by falling, can occur (mostly in adolescents) following, or even before, any injection with a needle. Therefore inform the physician, pharmacist or nurse if the patient fainted with a prior injection.

Adults above 45 years of age: adults above 45 years of age should not receive the vaccine.

Driving and using machines: no data are available on the effects of dengvaxia on the ability to drive or use machines.

Use in children: Children less than 9 years of age should not receive the vaccine.

 

Side effects:

Like all medicines, dengvaxia can cause side effects, although not all patients get them.

Serious allergic reactions: If any of these symptoms occur after leaving the place where the patient received an injection, consult a physician immediately: difficulty in breathing, blueness of the tongue or lips, a rash, swelling of the face or throat, low blood pressure causing dizziness or collapse.

When these signs and symptoms occur they usually develop quickly after the injection is given and while the patient is still in clinic or physician's surgery.

Serious allergic reactions are very rare (may affect up to 1 in 10,000 people), after receiving any vaccine.

Other side effects: The following side effects were reported during clinical studies in children, adolescents and adults (from 9 to and including 60 years of age). Most of the reported side effects occurred within 3 days after the injection of the vaccine: very common (may affect more than 1 user in 10): headache, muscle pain (myalgia), generally feeling unwell (malaise), feeling of weakness (asthenia), injection site pain, fever.

Common (may affect up to 1 user in 10): Injection site reactions: redness (erythema), bruising (hematoma), swelling, and itching (pruritus).

Uncommon (may affect up to 1 user in 100): Infections of the upper respiratory tract, dizziness, sore throat (oropharyngeal pain), cough, runny nose (rhinorrhea), nausea, skin eruption (rash), neck pain, hardening of skin at the injection site (injection site induration).

Additional side effects in adults (from 18 to and including 60 years of age): Uncommon (may affect up to 1 user in 100): swollen glands (lymphadenopathy), migraine, joint pain (arthralgia), flu-like symptoms (influenza-like illness).

Additional side effects in children and adolescents (from 9 to and including 17 years of age: Uncommon (may affect up to 1 user in 100), Itchy rash (urticaria).

Reporting of side effects or any suspected adverse event: If the patient experiences any side effects after vaccination, advised to seek immediate medical attention.

By reporting side effects, it can help provide more information on the safety of the vaccine.

 

Interactions:

Using other medicines and dengvaxia: Dengvaxia may not have an optimal effect if it used at the same time as medicines that suppress the immune system such as corticosteroids or chemotherapy.

Inform the physician, pharmacist or nurse if the patient is taking or has recently taken any other vaccines or any other medicines, including medicines obtained without a prescription.

 

Caution for usage:

Before administering any biological, the person responsible for administration must take all precautions to prevent allergic or other reactions. As with all injectable vaccines, appropriate medical treatment and supervision must always be readily available in the event of an anaphylactic reaction following the administration of dengvaxia.

Epinephrine (1:1000) and other appropriate agents used to control immediate allergic reactions must be available to treat unexpected events such as anaphylaxis.

Dengvaxia must not be mixed with other medicinal products in the same syringe.

Dengvaxia must not be administered by intravascular injection under any circumstances.

Syncope (fainting) can occur following, or even before, any vaccination as a psychogenic response to injection with a needle. Procedures should be in place to prevent injury from falling and to manage syncopal reactions.

Separate syringes and needles, separate injection sites and preferably separate limbs must be used if any other vaccine (s) or medicinal product (s) is/are concomitantly administered.

Dengvaxia is reconstituted by transferring all the solvent (0.4% sodium chloride solution) provided in the blue-labeled pre-filled syringe into the vial of freeze dried powder with a yellowish green flip off cap. The pre-filled syringe is fitted with a sterile needle for this transfer. The vial is then gently swirled. After complete dissolution, a 0.5 ml dose of reconstituted suspension is withdrawn into the same syringe. For injection, the syringe should be fitted with the new sterile needle.

The suspension should be visually inspected prior to administration. After reconstitution, dengvaxia is clear, colorless liquid with the possible presence of white to translucent particles (of endogenous nature).

After reconstitution with the solvent provided, dengvaxia must be used immediately.

Any unused dengvaxia or waste material should be disposed of, preferably by heat inactivation or incineration, in accordance with local regulations.

Do not throw away any medicines via wastewater or household waste. Ask a pharmacist on how to throw away medicines that no longer use. These measures will help to protect the environment.

 

Storage

Store in a refrigerator (2°c-8°c). Do not freeze. Keep the vaccine in the outer carton in order to protect it from light.

 

Description

After reconstitution, one dose (0.5 ml) contains 4.5-6.0 log10 ccid50* of each serotype of the cyd dengue virus** (1, 2, 3 and 4).

* ccid50: 50% cell culture infectious dose.

** produced in serum-free vero cells by recombinant dna technology.

The powder is a white, homogenous, freeze-dried powder with possible retraction at the base, and may form a ring-shaped cake.

The solvent (0.4% sodium chloride solution) is a clear, colorless liquid.

After reconstitution with the solvent provided, dengvaxia is a clear, colorless liquid with the possible presence of white to translucent particles.

Excipients/inactive ingredients: essential amino acids including l-phenylalanine, non-essential amino acids, l-arginine hydrochloride, sucrose, d-trehalose dihydrate, d-sorbitol, trometamol, urea, sodium chloride, water for injections.

 

Mechanism of action:

Dengvaxia contains dengue virus serotypes 1, 2, 3 and 4 that have been weakened. Dengvaxia works by stimulating the body's natural defenses (immune system), which produces its own protection (antibodies) against the viruses that cause dengue disease.

Dengue is a viral infection transmitted to humans through the bite of an infected aedes mosquito. Dengue is not transmitted directly from person-to-person. Nevertheless the virus which replicates in an infected individual can be transmitted to other humans through mosquito bites for 4-5 days (maximum 12 days) after the first symptoms appear.

Dengue disease results in a wide range of symptoms including fever, headache, pain behind the eyes, muscle and joint pain, nausea, vomiting, swollen glands or skin rash. Symptoms usually last for 2-7 days. Dengue disease can also be asymptomatic.

However, occasionally dengue can be severe and potentially lead to hospitalization and in rare cases to death. Severe dengue is characterized by high fever and any of the following symptoms: severe abdominal pain, persistent vomiting, rapid breathing, severe bleeding, bleeding in stomach, bleeding gums, fatigue, restlessness, coma, seizure and organ failure.

Source:- http://www.mims.com/philippines/drug/info/dengvaxia

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