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Dear Dr. I am a 50 year male. I have nerve compression problem of spine for the last 10 years. I visited Dr. At Panchkula for ozone therapy. The Dr. Injected four injections in my four discs. Now I feel nerve compression with little less intensity than before but I still cannot walk freely. Moreover, I feel heaviness in my back where injections have been given. What should I do for removing nerve compression so that I may be able to walk freely without pain.
Parkinson's disease is a disorder of the brain that leads to tremors and difficulty with walking, movement and coordination. It most often develops in people age 50 or older and is one of the most common nervous system disorders of the elderly, according to the National Institutes of Health. There is no known cure.
The major 12-year study in Taiwan found that while diabetes increases the risk of Parkinson's 2.2 fold, including metformin in the therapy negates that risk.
“An exciting aspect of the finding is that metformin seems to be working to protect the brain against neurodegeneration which contributes to Parkinsonism. This means it may also be considered a relevant therapy for the prevention of dementia as well,” said Mark Wahlqvist, professor at the National Health Research Institutes in Taiwan and lead author of the study.
Metformin is the first-line medication for patients with type 2 diabetes. This affordable and commonly prescribed oral drug lowers blood glucose levels by decreasing the amount of glucose produced by the liver and enhancing insulin action. It's a type of biguanide drug used since the 1950s with a relatively safe record.
Researchers also found that use of sulfonylurea drugs, a common treatment for diabetes, further increases the risk by about 57 percent.
Sylfonylureas are a category of oral medications that stimulate the beta cells of the pancreas to release more insulin, according to the American Diabetes Association. Sylfonylurea drugs have been in use since the 1950s and include glipizide, glyburide, glimepiride and chlorpropamide.
Researchers theorize that metformin may re-set the regulation of energy metabolism in the brain cells. They suspect that exercise and diet may have the same energy regulating effect.
The study does not examine the mechanism behind metformin's protective effect on the brain. Researchers say that additional research is needed in this area.
Past research has shown that metformin reduces cardiovascular mortality and several cancers, including those of the large bowel, liver and pancreas.
Sir I often forget things like, where do I kept my phone an like those thing. Initially it was like I rarely use to forgot, but now it's like a usual thing for me now. I am very worried about my memory power. So I want to know what are the real causes of memory loss and further I am student of engineering, and I can't remember the topics that I had studied 2 or 3 days ago? Also I wanna know how to increase memory power an what food should I eat to increase my memory?
My voice is always not cleared and rough and I also cannot speak loudly, what I can do It's daily problem. Thanks.
I am having problem of over thinking, due to that I am suffering, stress in day today life. How can I overcome that and enjoy my present moment.
I smoke cannabis (ganja) for first time on 24 September. Till now I am affecting by it.In previous two days suddenly I had in a dream. When will I get relief from it & how?
Alternating between being happy and sad as you go through life's ups and downs is normal, but if you're sad most of the time, it could be a sign of being depressed. Depression takes the joy out of all your activities, and can make merely getting through a day feel overwhelming. The first step to overcoming this problem is to understand its symptoms and causes. Not everyone experiences depression the same way, but here are a few questions that can help tell you if you are depressed or not.
Do you feel helpless?
It is common for depressed people to feel helpless and that everything around them is out of their control. As a result, the person may either stop participating in activities all together or try to control things they can't. Both situations are cyclic and lead to further depression.
Have you lost interest in daily activities?
The feeling of helplessness is one of the main reasons depressed people lose interest in activities. Another reason is that activities that were once enjoyed now do not seem interesting enough. In most cases, this leads to the person isolating himself and withdrawing from all his family and friends.
Do you often feel angry or irritated?
Depression is almost always accompanied by irritability and anger. Small annoyances that would usually be overlooked quickly, take on an inappropriate significance. This can lead to poor impulse control, substance abuse and anxiety disorder. In most cases, anger and depression are related by the person trying to take accountability for things that are out of his control and hence feeling helpless.
Is there a change in your sleep pattern?
Your sleep quality is very closely related to the way you feel. Depressed people often suffer either from insomnia or oversleeping. Depressed people can have trouble going to sleep as well as staying asleep. This can cause drowsiness and lethargy during the day. Sleep apnea is also linked with depression. As you can imagine, if this is left untreated, it will only worsen your depression.
Do you feel tired?
When the body does not get adequate sleep, you begin the day feeling tired. Thus depressed people often feel fatigued and complain of a number of muscle and joint pains. This is because the body has not had enough time to regenerate cells during the night. This is usually complemented by complains of persistent headaches and stomach aches, both of which are emotionally connected to the way you feel.
The nature of depression is such that it lowers a person's self esteem to the point of interfering with his ability to seek help. Hence if you have a positive response to the above questions, it is time to address your problem before it worsens. If you wish to discuss about any specific problem, you can consult a Psychiatrist.
Dear sir, Hame bhulne ki bahut galat habit h , hm kuchh v read karte h to 1 hours ke baad kuchh v yaad nahi rehta hai isliye please btaye ki memory power ko kaise increase kiya ja sakta h .aur mujh me ek sirf galat habit h ki hm 5 se 6 din me ek baar (muth )hast mathun karte hai please btaye .
How long does it takes to recover from anorexia nervosa? I really want help, and I do not want to look pale or yellowish. Can anyone please tell about the correct diet chart and weight according to my age, i.e. 21 yrs. And how much time it take to recover, and suggestions for the recovery.
While it is well known that smoking causes lung cancer, heavy smokers with diabetes are also at increased risk of death from causes other than lung cancer, according to a study being presented next week at the annual meeting of the radiological society of north america (rsna).
Diabetes is a chronic illness in which there are high levels of glucose in the blood. More than 29 million people in the u. S. Have diabetes, up from the previous estimate of 26 million in 2010, according to a report released by the centers for disease control and prevention. One in four people with diabetes doesn't know he or she has it. Having diabetes can also put people at risk for numerous other health complications.
To determine the extent to which diabetes is associated with deaths from lung cancer, other cancers, and other causes among heavy smokers, researchers examined the risk for all-cause mortality among people with and without diabetes within the national lung screening trial (nlst), a massive, multicenter trial that compared low-dose helical ct with chest x-ray for early detection of lung cancer in current and former heavy smokers.
" in our study, we found a statistically significant link between diabetes and all-cause deaths, non-lung cancer deaths and lung cancer deaths in women" said kavita garg, m. D, professor of radiology from the university of colorado -- denver.
For the study, Dr. Garg and colleagues looked at data from 53, 454 participants in the nlst and identified 5, 174 participants who reported having diabetes at screening.
They conducted an analysis of the relative risk for overall mortality, lung cancer mortality, and non-lung cancer mortality associated with diabetes, adjusting for age, gender, body mass index (bmi), and pack-years of smoking. Over the course of the study, there were 3, 936 total deaths, including 1, 021 from lung cancer and 826 from cancers not of the lung.
Participants with diabetes tended to be older, reported more pack-years of smoking, and had a higher bmi than those without diabetes. There were 650 deaths (12.6 percent of patients) among participants with diabetes and 3, 286 deaths (6.8 percent of patients) among participants without diabetes.
" we found that diabetes doubles the risk for all-cause mortality and non-lung cancer mortality among heavy smokers" Dr. Garg said" we also found that women with diabetes have an increased risk of lung-cancer mortality, but did not find the same effect in men"
The researchers continue to analyze data in an effort to better understand the underlying cause. In the meantime, Dr. Garg emphasizes the importance of taking control of diabetes and undergoing lung cancer screening if you're a smoker.
" patients have to take care of their diabetes to maximize the benefit of ct screening for lung cancer" she said" it truly makes a magnitude of difference in mortality risk"