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Dr. Mamta Thomas

Dentist, Bangalore

Dr. Mamta Thomas Dentist, Bangalore
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I'm dedicated to providing optimal health care in a relaxed environment where I treat every patients as if they were my own family....more
I'm dedicated to providing optimal health care in a relaxed environment where I treat every patients as if they were my own family.
More about Dr. Mamta Thomas
Dr. Mamta Thomas is a renowned Dentist in Outer Ring Road, Bangalore. You can visit her at Smilez 4u Dental Clinic in Outer Ring Road, Bangalore. Book an appointment online with Dr. Mamta Thomas and consult privately on Lybrate.com.

Lybrate.com has a number of highly qualified Dentists in India. You will find Dentists with more than 42 years of experience on Lybrate.com. You can find Dentists online in Bangalore and from across India. View the profile of medical specialists and their reviews from other patients to make an informed decision.

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#93/4, 2nd Cross, Outer Ring Road, Marathalli. Landmark: Near Marathahalli BridgeBangalore Get Directions
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Dengue Vaxia

M.B.B.S,C.C.A,D.C.A,AASECT,FPA,AAD,M.I.M.S
General Physician,
Dengue Vaxia

Dengvaxia - first vaccine against dengue

Dengvaxia is a vaccine used to help protect adult or children against dengue disease caused by dengue virus serotypes 1, 2, 3 and 4. Dengvaxia is given to adults, adolescents and children 9 through 45 years of age living in endemic areas.

Read more:

Dengue symptoms and what to do if you think you have denguedengue fever - remedies using papaya leaf juice

Full prescribing info - dengvaxia

Contents

Dengue tetravalent vaccine (live, attenuated).

Indications / uses

Dengvaxia is a vaccine used to help protect adult or children against dengue disease caused by dengue virus serotypes 1, 2, 3 and 4. Dengvaxia is given to adults, adolescents and children 9 through 45 years of age living in endemic areas.

Dosage / direction for use

The patient will receive 3 injections of 0.5 ml each at 6-month intervals.

The first injection will occur at the chosen or scheduled date; the second injection, 6 months after the first injection; and the third injection, 6 months after the second injection. Dengvaxia should be used according to the local vaccination schedule.

If the patient forgot an injection of dengvaxia: if the patient missed a scheduled injection, the physician will decide when to give the missed injection.

It is important that the patient follows the instructions of the physician, pharmacist or nurse regarding return visits for the follow-up injection. If the patient forgets or is not able to go back to the physician, pharmacist or nurse at the scheduled time, ask the physician, pharmacist or nurse for advice.

Administration: dengvaxia is given by the physician or nurse as an injection underneath the skin (subcutaneous route) in the upper arm.

Contraindications

Do not use dengvaxia if the patient is allergic (hypertensive) to the active substances or any of the other ingredients of dengvaxia listed in description (see description); has developed an allergic reaction after prior administration of dengvaxia. Signs of an allergic reaction may include an itchy rash, shortness of breath and swelling of the face and tongue; is suffering from a disease with mild to high fever or acute disease. In this case, the physician will postpone the administration of dengvaxia until the patient has recovered; has a weakened immune system, for example due to a genetic defect, hiv infection or therapies that affect the immune system (for example, high-dose corticosteroids or chemotherapy); is pregnant; is breastfeeding.

Use in pregnancy lactation: dengvaxia must not be given to pregnant or breastfeeding women.

If the patient is of child-bearing stage, the patient should take the necessary precautions to avoid pregnancy for 1 month following administration of dengvaxia; is pregnant or breastfeeding, the patient thinks may be pregnant or is planning to have a baby, ask the physician, pharmacist or nurse for advice before receiving dengvaxia.

Special precautions

Inform the physician, pharmacist or nurse before receiving dengvaxia if the patient is taking an immunosuppressive treatment (prednisone or equivalent to 20 mg or 2 mg/kg for 2 weeks or more). The physician will postpone administration of dengvaxia until 4 weeks after the treatment is discontinued; has experienced any health problems after prior administration of any vaccines. The physician will carefully consider the risks and benefits of vaccination.

As with all vaccines, dengvaxia may not protect 100% of persons who have been vaccinated. Vaccination with dengvaxia is not a substitute for protection against mosquito bites. The patient should take appropriate precautions to prevent mosquito bites, including the use of repellents, adequate clothing, and mosquito nets.

Fainting, sometimes accompanied by falling, can occur (mostly in adolescents) following, or even before, any injection with a needle. Therefore inform the physician, pharmacist or nurse if the patient fainted with a prior injection.

Adults above 45 years of age: adults above 45 years of age should not receive the vaccine.

Driving and using machines: no data are available on the effects of dengvaxia on the ability to drive or use machines.

Use in children: children less than 9 years of age should not receive the vaccine.

Side effects

Like all medicines, dengvaxia can cause side effects, although not all patients get them.

Serious allergic reactions: if any of these symptoms occur after leaving the place where the patient received an injection, consult a physician immediately: difficulty in breathing, blueness of the tongue or lips, a rash, swelling of the face or throat, low blood pressure causing dizziness or collapse.

When these signs and symptoms occur they usually develop quickly after the injection is given and while the patient is still in clinic or physician's surgery.

Serious allergic reactions are very rare (may affect up to 1 in 10, 000 people), after receiving any vaccine.

Other side effects: the following side effects were reported during clinical studies in children, adolescents and adults (from 9 to and including 60 years of age). Most of the reported side effects occurred within 3 days after the injection of the vaccine: very common (may affect more than 1 user in 10): headache, muscle pain (myalgia), generally feeling unwell (malaise), feeling of weakness (asthenia), injection site pain, fever.

Common (may affect up to 1 user in 10): injection site reactions: redness (erythema), bruising (hematoma), swelling, and itching (pruritus).

Uncommon (may affect up to 1 user in 100): infections of the upper respiratory tract, dizziness, sore throat (oropharyngeal pain), cough, runny nose (rhinorrhea), nausea, skin eruption (rash), neck pain, hardening of skin at the injection site (injection site induration).

Additional side effects in adults (from 18 to and including 60 years of age): uncommon (may affect up to 1 user in 100): swollen glands (lymphadenopathy), migraine, joint pain (arthralgia), flu-like symptoms (influenza-like illness).

Additional side effects in children and adolescents (from 9 to and including 17 years of age: uncommon (may affect up to 1 user in 100): itchy rash (urticaria).

Reporting of side effects or any suspected adverse event: if the patient experiences any side effects after vaccination, advised to seek immediate medical attention.

By reporting side effects, it can help provide more information on the safety of the vaccine.

Click to view adr monitoring form

Interactions

Using other medicines and dengvaxia: dengvaxia may not have an optimal effect if it used at the same time as medicines that suppress the immune system such as corticosteroids or chemotherapy.

Inform the physician, pharmacist or nurse if the patient is taking or has recently taken any other vaccines or any other medicines, including medicines obtained without a prescription.

Caution for usage

Before administering any biological, the person responsible for administration must take all precautions to prevent allergic or other reactions. As with all injectable vaccines, appropriate medical treatment and supervision must always be readily available in the event of an anaphylactic reaction following the administration of dengvaxia.

Epinephrine (1: 1000) and other appropriate agents used to control immediate allergic reactions must be available to treat unexpected events such as anaphylaxis.

Dengvaxia must not be mixed with other medicinal products in the same syringe.

Dengvaxia must not be administered by intravascular injection under any circumstances.

Syncope (fainting) can occur following, or even before, any vaccination as a psychogenic response to injection with a needle. Procedures should be in place to prevent injury from falling and to manage syncopal reactions.

Separate syringes and needles, separate injection sites and preferably separate limbs must be used if any other vaccine (s) or medicinal product (s) is/are concomitantly administered.

Dengvaxia is reconstituted by transferring all the solvent (0.4% sodium chloride solution) provided in the blue-labeled pre-filled syringe into the vial of freeze dried powder with a yellowish green flip off cap. The pre-filled syringe is fitted with a sterile needle for this transfer. The vial is then gently swirled. After complete dissolution, a 0.5 ml dose of reconstituted suspension is withdrawn into the same syringe. For injection, the syringe should be fitted with the new sterile needle.

The suspension should be visually inspected prior to administration. After reconstitution, dengvaxia is clear, colorless liquid with the possible presence of white to translucent particles (of endogenous nature).

After reconstitution with the solvent provided, dengvaxia must be used immediately.

Any unused dengvaxia or waste material should be disposed of, preferably by heat inactivation or incineration, in accordance with local regulations.

Do not throw away any medicines via wastewater or household waste. Ask a pharmacist on how to throw away medicines that no longer use. These measures will help to protect the environment.

Storage

Store in a refrigerator. Do not freeze. Keep the vaccine in the outer carton in order to protect it from light.

Description

After reconstitution, one dose (0.5 ml) contains 4.5-6.0 log10 ccid50* of each serotype of the cyd dengue virus** (1, 2, 3 and 4).

* ccid50: 50% cell culture infectious dose.

** produced in serum-free vero cells by recombinant dna technology.

The powder is a white, homogenous, freeze-dried powder with possible retraction at the base, and may form a ring-shaped cake.

The solvent (0.4% sodium chloride solution) is a clear, colorless liquid.

After reconstitution with the solvent provided, dengvaxia is a clear, colorless liquid with the possible presence of white to translucent particles.

Excipients/inactive ingredients: essential amino acids including l-phenylalanine, non-essential amino acids, l-arginine hydrochloride, sucrose, d-trehalose dihydrate, d-sorbitol, trometamol, urea, sodium chloride, water for injections.

Mechanism of action

Dengvaxia contains dengue virus serotypes 1, 2, 3 and 4 that have been weakened. Dengvaxia works by stimulating the body's natural defenses (immune system), which produces its own protection (antibodies) against the viruses that cause dengue disease.

Dengue is a viral infection transmitted to humans through the bite of an infected aedes mosquito. Dengue is not transmitted directly from person-to-person. Nevertheless the virus which replicates in an infected individual can be transmitted to other humans through mosquito bites for 4-5 days (maximum 12 days) after the first symptoms appear.

Dengue disease results in a wide range of symptoms including fever, headache, pain behind the eyes, muscle and joint pain, nausea, vomiting, swollen glands or skin rash. Symptoms usually last for 2-7 days. Dengue disease can also be asymptomatic.

However, occasionally dengue can be severe and potentially lead to hospitalization and in rare cases to death. Severe dengue is characterized by high fever and any of the following symptoms: severe abdominal pain, persistent vomiting, rapid breathing, severe bleeding, bleeding in stomach, bleeding gums, fatigue, restlessness, coma, seizure and organ failure.

Source:- http://www.mims.com/philippines/drug/info/dengvaxia

More information about dengvaxia - first vaccine against dengue

Sanofi awaits govt approval to launch dengue vaccine in india

Sanofi pasteur - dengue vaccine frequently asked questions

13 people found this helpful

How to whiten my teeth?

Advanced Aesthetics, BDS
Dentist,
Hi, there are various method / products available to whiten teeth. The most effective is in-office whitening done by a dental professional. It's usually a one hour procedure in which whitening gel will apply to the teeth and activate by whitening light for 10 to 15 minutes. 2 or 3 such sessions may required.
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I am 24 year old boy and I am suffering from teeth problem half portions of 2 molars are crode of right side lower.

Advanced Aesthetics, BDS
Dentist, Mumbai
Hi , we can't comment without checking your teeth clinically. You can send some x-rays or can come for a check-up (free of cost) to figure the exact cause and solution.
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Madam/sir recently I taking route canal treatment only for two days and after I not it to be continue. It would be happen 15 days ago. Now my teeth are pain so give me which tablet are taking. Please reply.

BDS (GOLD MEDALIST)
Dentist, Jamshedpur
Madam/sir recently I taking route canal treatment only for two days and after I not it to be continue. It would be ha...
You should complete the processes of r. C. T. Otherwise it will get infection in root area and will cause more pain and discomfort. Painkillers are only for temporary relief. You can take tab. Ketorol -dt 2 tabs dissolved in half cup of water. Or tab. Ibuprofen after meal.
2 people found this helpful
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Sir, I am suffering from teeth/gums pain,since two days also I have Diabetic which is under control. Any medicine for early recovery ?

BDS
Dentist, Mumbai
Sir, I suggest you take Augmenting 625mg TId for three days , Flagyl -400 mg TId for three days,Espidase -P TId for three days.If you feel better you can take it for 5 days. Cap Becozinc 1 daily for 15 days too. I suggest sir that you consult with a local dentist.Or we can help. You too. Proper examination and proper diagnosis would make it easier for us to help you.
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I am 18 years old male and my front teeth got broken half, 5 years ago. So what treatment can be done and what it cost. I cannot afford expensive treatment.

BDS
Dentist, Jaipur
I am 18 years old male and my front teeth got broken half, 5 years ago. So what treatment can be done and what it cos...
You should go with rct after that crown placement. Expenses varies on doctor to doctor approx 2500/rs along with crown placement.
3 people found this helpful
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I have been suffering from tooth ache since 3 months near the jaw location many of the doctors confirmed that it was wisdom teeth. The pain was unbearable so please give the suggestion whether I have to remove it completely or use any capsules. thanks you.

MDS - Oral & Maxillofacial Surgery
Dentist, Mohali
I have been suffering from tooth ache since 3 months near the jaw location many of the doctors confirmed that it was ...
If it is the wisdom tooth, better go for extraction. But do tell about your allergies to your dental surgeon before treatment.
7 people found this helpful
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BDS
Dentist, Panchkula
Smiling can reduce your blood pressure. Keep smiling!
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I have got a mouth-sore inside my mouth(near the extreme teeth) resulting acute pain. Used mouth jel namely ORAjel . But no relief. Please advice.

BDS
Dentist, Mumbai
You are probably having a impacted last molar which is causing bite and resulting into ulcer ,go to the dental surgeon he will do the needful and treat this problem by cuspal grinding and dressing of ulcer with desired medication.
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I am grinding my teeth every day and night. when i'm sleeping any tablet to cure this.?

BDS
Dentist, Mumbai
I am grinding my teeth every day and night. when i'm sleeping any tablet to cure this.?
Your condition is called bruxism. You need night guard. It can be made from any dentist. It is not expensive but will help you a lot. Read more about bruxism or consult me. Will be happy to help you for free.
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How to get white teeth.

Advanced Aesthetics, BDS
Dentist,
How to get white teeth.
Hi, you need to get a professional cleaning done. If that does not help then you may go for teeth whitening. Regards
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I'm having a mouth sore or ulcer what you call since 3-4 daus it is under the lips its painful what should I do.

Certification in Full Mouth Rehabilitation, Post-Graduate Certificate in Oral Implantology (PGCOI), M.Sc - Master of Oral Implantology (MOI), Certified Implantologist, BDS
Dentist, Rajkot
I'm having a mouth sore or ulcer what you call since 3-4 daus it is under the lips its painful what should I do.
Use ulcer healing gel called HEXIGEL ,it will accelerate healing and take folic acid tab.for week ( 2 tab per day).
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MDS
Dentist, Nagpur
Kind of toothbrush to be used by adults:       We recommend a brush with soft bristles which helps in removing the plaque and debris thoroughly from the mouth.
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Hello, I am 22 years old male 5 years before I removed my right side upper teeth. Its slowly damaged my teeth structure now and gums upper portion partially damaged. So what should I do?

BDS
Dentist, Sangli
Hello, I am 22 years old male 5 years before I removed my right side upper teeth. Its slowly damaged my teeth structu...
You need to visit your dentist and get your missing teeth replaced depending on the condition of your remaining teeth.
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Hi Is it myth or truth ki tulsi ki leaf teeth se chew karke khane se teeth karab ho jate hai.

BDS
Dentist, Rewari
Hi Is it myth or truth ki tulsi ki leaf teeth se chew karke khane se teeth karab ho jate hai.
True Tulsi leaves should not be chewed .Soak tulsi leaves in water or tea and take the drink after removing them
1 person found this helpful
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I am a 22 years male I have a tongue ulcer. what do I do for rapid treatment?

MDS, BDS
Dentist,
Take vit b complex twice daily for two weeks and dentogel apply over the ulcer thrice daily or just before having food so that it won't burn and cause pain.
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What I do to make my gum pink ? these black gums spoils my personality. Please suggest me what I do ?

MDS - Oral & Maxillofacial Surgery
Dentist, Chennai
What I do to make my gum pink ? these black gums spoils my personality. Please suggest me what I do ?
Cause of discoloration ? Smoking, coffee, tea, drugs, aging, staining food (wine, blueberry, etc) genetics. Quit habits if any. We need more investigations to decide upon treatment. Advance procedures (for pink gums) can be done with laser. DENTAL TIPS: - Visit a dentist every six months for cleaning and a thorough dental check-up. Limit sugary food to avoid tooth decay. Gargle your mouth thoroughly after every meal. Scrub gently to clean your tongue with a tongue cleaner. Floss all your teeth inter dentally & brush twice daily, morning & night, up & down short vertical strokes, with ultra-soft bristles, indicator brush. Tooth brush to be changed every 2 months.
1 person found this helpful
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I've got bad breath. My mouth dries very often. Is there anything I can do to avoid it and solve myhalitosis. Please help me.

BDS
Dentist, Kolar
Bad breath can b caused fue to various reasons. Due to smoking n using tobacco products, dental prob such as decay teeth, unclean tongue, gum infections, reduced saliva n dry mouth, ill fitting dentues, salivary gland probs. Other diseases n infections which also cause bad breath r sinus infections, respiratory tract infections such as bronchitis n pneumonia, liver n kidney probs, diabetes, acid reflux from stomach etc. Get scalling done by dentist. Use proper brushing techniques. Brush, floss n use mouthwash twice daily. Massage your gums with your finger tips after brushing. Keep your tongue clean. Rinse your mouth well after each meal. Get your decay teeth filled. Visit your dentist for dental checkups every 6 months to detect n prevent dental probs. Drink plenty of fluids n lime juice. Inspite of these measures if bad breath persists, consult a general physician for further evaluation.
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I have mouth pain. Please advise.

CERTIFIED ORAL IMPLANTOLOGIST, NON-RESIDENT J.R. IN DEPTT. OF ORTHODONTICS, BDS
Dentist,
You can take painkiller like lyser-d for pain relief. But exact problem can be diagnosed only if you visit a dentist.
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