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Serum PSA and Testosterone Levels
Serum PSA levels may useful for diagnosing hypogonadism (low testosterone), Italian researchers say.
In the past, the relationship between PSA levels and testosterone has been difficult to define, as some researchers have found a connection and others have not.
The goals of this study were to better understand this possible relationship for men with sexual dysfunction and to determine whether PSA levels may give information about testosterone levels.
Almost three thousand men participated in the study. All of them were seeking treatment for sexual dysfunction and had PSA levels of less than 4 ng/mL. They ranged in age from 18 to 85 with a mean age of 52.5 ± 12.4 years.
A variety of physical measurements were conducted, including blood pressure, waist circumference, testis volume, total testosterone, HDL cholesterol, and triglycerides. Also, each man was interviewed using the Structured Interview on Erectile Dysfunction (SIEDY), ANDROTEST, a tool that screens for hypogonadism in men with erectile dysfunction, and PsychoANDROTEST, which examines the psychological signs and symptoms of low testosterone.
After adjusting for age, the researchers found that low PSA levels were associated with delayed puberty and lower testis volume, two markers of hypogonadism. Low PSA was also associated with metabolic syndrome, type 2 diabetes, and cardiovascular diseases.
Two other aspects of the research were noted.
First, the authors reported that the “saturation hypothesis” was supported. The connection between PSA levels and testosterone was only present when men’s testosterone levels were lower than average. For men with normal testosterone levels, the relationship was not as clear.
In this study, PSA levels did not rise substantially when total testosterone levels were above 8 nmol/L.
“It might be inferred that [testosterone] therapy in men with values above this point would not be expected to result in a rise in PSA, whereas men with [testosterone] values below this point may very well experience a rise in PSA,” the authors wrote.
Second, age appeared to play a role in the applicability of the findings. Using PSA levels to predict low testosterone was more accurate in younger patients.
“The efficacy of PSA, as a ‘screener’ for hypogonadism is modest and decreases as a function of aging, when PSA levels are affected by other factors, besides androgen activity,” the authors explained.
The study was published online in July in the Journal of Sexual Medicine.
The Journal of Sexual Medicine
Rastrelli, Giulia, MD, et al.
“Serum PSA as a Predictor of Testosterone Deficiency”
(Full-text. First published online: July 16, 2013)
- See more at: http://www.issm.info/news/sex-health-headlines/serum-psa-and-testosterone-levels#sthash.62jmdKR1.dpuf
I haven't been able to sleep since 2 days and I am having a severe headache, tried multiple home remedies, but didn't work, what to do? Please help me!
Hello sir/Mam I am sandeep 28 year, I am suffering from a very low stamina in my body and specially in my private part (penis. It is get early ejaculate M getting married after 6 months So can you please help me in this.
I'm 32 years old of married man, and i'm having a short penis and premature ejaculation. Can you pliz help me to have a longer and bigger penis to fulfill my wife desire.
I am 25 and suffering from stomach ache left side of my stomach, it's make me uneasy and also makes me heavy of my stomach.
My daughter is 13 years of age & her B12 count is 205.4 pg/ml. Her hemoglobin count is 11.1 g/dl. Additionally she suffers from low B. P. 98 on the lower side. Kindly guide.
I am 71 years old male. I tested my PSA level, it shows 6.9, is it normal or should go for medicine.
I am suffering from severe joints pain and knee pain. I used tb treatment before one year. please prescribed some medicine.
It is often believed that eggs tend to heat up your stomach and, hence, should be avoided as much as possible. People believe that eating eggs during the hot summer months can lead to detrimental health effects. One of the reasons attributed to this belief is that eggs contain copious amounts of cholesterol, which can generate tremendous amounts of body heat.
However, contrary to popular belief, eggs do not heat up your system and perfectly safe for consumption during the season of some summer.
Having eggs for breakfast helps you with the following:
1. Cholesterol Factor - To be precise, a single egg provides 212 mg of cholesterol out of the recommended 300 mg. However, cholesterol in your diet does not raise the cholesterol levels in your blood. This happens because the liver produces a high quantity of cholesterol each day, and when you eat more eggs causing your cholesterol levels to rise, the liver starts producing less of it. In fact, a study found that eggs didn't raise cholesterol in 70% of its test subjects.
2. Provides Choline - Choline is a substance, which is required by the body to build cell membranes and to perform a horde of other functions like liver function, brain development, nerve, and muscle function. Lack of choline could lead to disruption of these functions. Whole eggs contain more than 100 mg of this less known nutrient, and therefore, should be a part of your diet.
3. Contains Lutein and Zeaxanthin - One of the gradual symptoms of aging is worsening eyesight. There are many types of nutrients that help in countering this degenerative process. Two such nutrients are lutein and zeaxanthin, which eggs are rich in. These two antioxidants help to build up the retina of the eye. Moreover, they also help in preventing eyesight conditions like cataracts and macular degeneration. Eggs are also rich in Vitamin A, the lack of which is the most common cause of blindness worldwide.
4. Reduces risk of stroke - For many decades, eggs have been unfairly criticized. A popular misbelief was that high cholesterol in eggs made them a cause for cardiac problems. In a review, which accounted for 17 studies and a total of 263,938 participants, no associations were found between eggs and heart diseases. Eggs are also highly filling and help to lose weight to a certain extent.
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Related Tip: Struggling with Weight loss? Try Eggs for Breakfast!