Doctor in Origon Hospital
Caesarean Section Procedure
Treatment Of Female Sexual Problems
Termination Of Pregnancy Procedure
Treatment Of Pregnancy Problems
Well Woman Healthcheck
Treatment Of Female Sexual Problems
Treatment Of Medical Diseases In Pregnancy
Treatment Of Menstrual Problems
Intra-Uterine Insemination (IUI) Treatment
Medical Termination Of Pregnancy (Mtp) Procedure
Gynecology Laparoscopy Procedures
Pap Smear Procedure
Urinary Incontinence (Ui) Treatment
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The concept of egg quality of a woman is derived from the belief that the embryo implantation probability is powerfully related to the age and ovarian reserve of the woman. Thus, it is regarded that the quality of the egg is almost synonymous with the chances of embryo implantation. Its quality cannot be assessed merely by looking at the egg or measuring its ability to receive the fertilization by sperm or simply observing the initial embryo division.
There are a few important factors that contribute to the success or failure of the embryo implantation and some of them are:
- Diminished ovarian reserve: A woman with an increased FSH level on the third day of the menses is regarded as having diminished reserve of the ovary. This implies that her ovary is not competent in sending feedback signals to the pituitary gland and the body responds by producing an increased amount of FSH for stimulating the ovary. For more than 10 years, it has been found that in over thousands of fertility treatment cycles, women with an increased FSH level have a lower egg quality.
- The advanced age of maternity: Even though the FSH level is normal, the age of the mother who provides the eggs plays an important role to determine the quality of the egg. Quite like women with increased FSH levels, eggs obtained from women aged more than 40 years can have some problems at a later stage of fertilization. Normal FSH levels are not considered a reassuring factor, owing to the lower implantation rate in females aged over 45 years.
- Diminished quality of egg: With an increase in age, the capacity of the mitochondria in producing energy slowly decreases. The egg is linked to the circulation before ovulation, and it is linked again after the embryo implantation. But during the one week time ranging from ovulation to implantation, the egg and the resulting embryo are contained in the zona pellucida and function on the basis of mitochondrial energy supply. The older age of the woman doesn’t cause any problem at the initial stage of ovulation. Its fertilization and embryonic development are also normal. But soon, it runs out of energy and stops dividing before reaching the stage of implantation.
Therefore, it is important to have the eggs tested to find out any sort of chromosomal abnormality. In case the mother is deficient of producing high-quality eggs, the best option is to have donor eggs.
Mitochondrial replacement (MRT, sometimes called mitochondrial donation) is a special form of in vitro fertilization in which the future baby's mitochondrial DNA comes from a third party. This technique is used in cases when mothers carry genes for mitochondrial diseases. The two most common techniques in the mitochondrial donation are pronuclear transfer and maternal spindle transfer.
Cells are the tiniest part of an organism including the human body but has various parts within, which have specific functions. The mitochondria, for instance, are the batteries of the cells and produce energy for all functions, including cellular movement and adequate cellular function.
The egg, being a single cell, also is highly dependent on the mitochondria for its optimal function. For an egg to be healthy, it should have optimal energy, and that comes only when the mitochondria is functioning at its best. This determines the overall quality of the egg too. Poor eggs, it is well established, is one of the major cause of infertility, as it cannot implant itself and sustain the entire term of pregnancy.
Studies have confirmed that eggs have more mitochondria than normal cells, as their energy requirements are higher.
The ovaries have cells called precursor cells, which eventually can become eggs and get fertilized. Studies have shown that when mitochondria from these precursor cells are infused into the fertilized egg, the overall quality of the egg improves and therefore improves chances of fertilization.
The mitochondrial transfer is the new technique which is being developed and has resulted in a baby but involves third-party IVF and hence is in an ethical debate.
Polycystic ovarian disease or PCOD is a disease of the ovary that is characterized by the larger size of the ovary, fluid-filled sacs in the ovary, multiple cysts etc. In this condition, the ovary is covered by a white, tough, and thick outer covering. PCOD can have many implications including hormonal imbalance, menstruation cycle related disorders, insulin production and its usage etc. Ayurveda explains PCOD as a Kapha disorder and aims at clearing the obstruction of Vata dosha of the pelvis, normalize the menstrual cycle and balance metabolism.
Ayurvedic approach in treating PCOD-
Ayurveda looks at a holistic approach of treatment wherein the mind and the body are treated as one. The first step towards treating PCOS disorder is to reduce body weight along with lifestyle modification. The next step aims at countering the condition of PCOD with Panchakarma - a century-old treatment mechanism of Ayurveda. Some of the Panchakarma methods used in treating PCOD include Vamana, Vasthi, Virechana, Nasya etc. Before applying the Panchakarma therapy, oral administration of medicated oil is necessary.
The flow of Panchakarma therapy for PCOD-
Administration of medicated oil: The oral medicated oil has fat burning capabilities. The medication is prepared using herbal decoction and suitable herbs. The oil clears the fat blockers created due to fat throughout the body.
- Vamana: Suitable herbal medication is prescribed to induce oral vomiting. It ensures that the toxin from inside the body comes out before the medication takes its effect on the source.
- Virechana: This is one of the cleansing methods that is prescribed in Panchakarma therapy. A patient is given herbal purgatives in the form of medicated oil to clear blockages of the Vata Dosha.
- Vasthi: This is the form of Panchakarma therapy that is meant for cleaning the alimentary canal. It has a calming effect on the Vata aggravation. This is the mode of medication where medicated herbal oil is injected through the anus. This procedure in Ayurveda is known as Anuvasana Vasthi. This is followed by another round of oil medication that has a mixture of herbal decoction, medicated oil, herbal paste, rock salt etc. This procedure is known as Nirooha Vasthi.
- Uthara Vasthi: This procedure is very different from normal Vasthi in terms of its administration, ingredients, and quantity. This medication is applied to the uterus through the vagina. This is one of the best therapy when it comes to treating polycystic ovarian syndrome.
- Nasya: Once all the above medication is administered, Nasya is applied to both the nostrils. This is the last stage of Panchakarma medication and is extremely important to treat the underlying condition. This is given in a specific dosage for a certain duration. The fact that it directly involves the pituitary gland, makes this medication even more useful.