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Overview

Palonosetron

Prescription vs OTC : Prescription by Doctor required

About Palonosetron

Palonosetron is a 5-HT3 antagonist. It is given post-cancer surgery to prevent feelings of vomiting and nausea caused by chemotherapy. It functions by prohibiting the action of serotonin in parts of the brain and the nervous system.

On using Palonosetron you may experience side effects such as headache, problems with bowel movement, chills, decreased urge to urinate, acidity, drowsiness, drying of the mouth, cough, bloating, bloody or black stools, eye irritation, feelings of discomfort, joint pain, muscle pain, skin rash, eye soreness, fatigue and rapid weight loss. Should the reactions persist or should any adverse reactions show consult your doctor.

Before using this medication tell your doctor if: you are allergic to any ingredient contained within Palonosetron, you have any other allergies, you have a history of heart disorders, you are taking apomorphine or any other medication, you are pregnant or are breastfeeding a baby.

The dosage for Palonosetron is determined by the doctor based on your condition and medical history. However, the usual dose in adults is about 0.5 mg taken orally (capsule) an hour before chemotherapy or 0.25 mg by IV infusion given as a single dose half an hour before chemotherapy.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the uses of Palonosetron

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the side effects of Palonosetron ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Key highlights of Palonosetron

    • Is It safe with alcohol?

      Interaction with alcohol is unknown. Please consult your doctor.

    • Are there any pregnancy warnings?

      Chepatron 0.25mg injection is probably safe to use during pregnancy.
      Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.

    • Are there any breast-feeding warnings?

      Chepatron 0.25mg injection is probably safe to use during breastfeeding. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      Caution is advised when driving or operating machinery.

    • Does this affect kidney function?

      There is no interaction between renal impairment and consuming this drug. So dose alteration is not needed.

    • Does this affect liver function?

      There is no data available. Please consult doctor before consuming the drug.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of Palonosetron, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Medicines containing Palonosetron

    Below is the list of medicines, which contains Palonosetron as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    How does this medication work?

    This medication belongs to the class of an antiemetic. It works by antagonizing the 5HT3 receptor, a subtype of serotonin receptors found in the body to inhibit serotonin activity.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

      What are the interactions of Palonosetron ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Medicine

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        Benadryl Dr Dry Cough Active Relief Syrup

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        Hytram 100Mg Injection

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        null

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      References

      • Palonosetron-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 14 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/palonosetron

      • Palonosetron-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 14 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00377

      • PALONOSETRON injection,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 14 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=PALONOSETRON

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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