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Overview

Macfuran 100 MG Capsule

Manufacturer :  Macleods Pharmaceuticals Pvt.Ltd
Medicine Composition :  Nitrofurantoin
Prescription vs OTC : Prescription by Doctor required

About Macfuran 100 MG Capsule

Macfuran 100 MG Capsule is administered to cure UTIs caused by a few typical kinds of bacteria. Lung inflammation is one of the major but very rare side effects of Macfuran 100 MG Capsule and usually occurs if the usage persists for more than half a year.

Damage to the liver is also another serious but infrequent adverse reaction of Macfuran 100 MG Capsule. If the therapy is a long term one, then certain tests will be administered to check whether all is good with liver functioning or not. Signs of liver damage include persistent itching, yellowing of the eye’s whites or the skin, vomiting, dark colored urine, nausea and reduced appetite.

Macfuran 100 MG Capsule can also result in damage to the nerves. Nerve damage is characterized by pain and numbness of the feet and the hands. Another adverse effect of Macfuran 100 MG Capsule is damage to the red blood cells. This condition is known as hemolysis, indicators of which include weakness, fatigue, tiredness and paling of the skin. This generally subsides once the usage is discontinued.

There are certain medications, administration of which is strictly advised against while using Macfuran 100 MG Capsule. These include antacids that contain certain ingredients such as magnesium trisilicate, sulfinpyrazone and probenecid.

Pregnant women who are in their term of pregnancy (38 to 42 weeks) should talk to their doctor before using this drug. Also, Macfuran 100 MG Capsule is usually advised against at the time of labor and delivery. This drug can be passed onto a mother’s breast milk and thus prove harmful for the baby that is being breastfed.

In case of the elderly, their kidney functioning isn’t usually at their best. Hence, any medicine, once inside their system, tends to stay there for a longer time, thus increasing the risks of various side effects.

Take per recommended schedule, at regular intervals around-the-clock. Complete full course of therapy; do not skip doses. Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake).

Diabetics should consult prescriber if using Clinitest® for glucose testing. Nitrofurantoin may discolor urine dark yellow or brown (normal). Use caution when driving or engaging in tasks that require alertness until response to drug is known.

Report chest pains or palpitations; pain on urination or blood in urine; skin rash; muscle weakness, pain, or tremors; excessive fatigue or weakness; other persistent adverse effects; or if condition does not improve.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    What are the uses of Macfuran 100 MG Capsule

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    What are the contraindications of Macfuran 100 MG Capsule ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    What are the side effects of Macfuran 100 MG Capsule ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    Key highlights of Macfuran 100 MG Capsule

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 1 to 3 hours.

    • What is the onset of action?

      This medicine is well observed orally. Food may increase the bioavailability of the medicine.

    • Are there any pregnancy warnings?

      This medicine is recommended for pregnant women. It is contraindicated in pregnant patients at term (38 to 42 weeks' gestation), during labor and delivery.

    • Is it habit forming?

      No habit forming tendencies were reported

    • Are there any breast-feeding warnings?

      This medicine is known to excreted through breast milk. This medicine is not contraindicated in children less than 3 months and glucose-6-phosphate dehydrogenase (G-6-PD) deficient infants.

    • Is It safe with alcohol?

      Avoid consuming alcohol while taking this medicine.

    • Is it safe to drive while on this medicine?

      This medicine might cause side effects that affect the alertness of the patient. Thus driving must be avoided.

    • Does this affect kidney function?

      This medicine might be avoided in patients with Clcr <50 mL/minute. Also avoid use in hemo and peritoneal dialysis and continuous arteriovenous or venovenous hemofiltration (CAVH/CAVHD).

    • Does this affect liver function?

      This medicine is probably safe to be used in patient with liver disease. Adjustment of dose might not be needed. Kindly consult for further details.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    What are the substitutes for Macfuran 100 MG Capsule ?

    Below is the list of medicines, which have the same composition, strength and form as Macfuran 100 MG Capsule , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      If you miss a dose of Macfuran 100 MG Capsule, take the missed dose as soon as you remember. If it's almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    Where is the Macfuran 100 MG Capsule approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    How does this medication work?

    The active constituent of this medication belongs to the class urinary anti-infectives. It works by inhibiting the cell wall synthesis by forming reactive intermediates by bacterial flavoproteins. These intermediates will alter the bacterial ribosomal proteins, DNA synthesis, RNA synthesis and cell wall synthesis.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

      What are the interactions of Macfuran 100 MG Capsule ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Consumption of alcohol must be avoided as alcohol may interact with this medicine and cause serious side effects.
      • Interaction with Lab Test

        Causes false-positive urine glucose with Clinitest®.
      • Interaction with Medicine

        • Decreased effect: Antacids, especially magnesium salts, decrease absorption of nitrofurantoin; nitrofurantoin may antagonize effects of norfloxacin.
        • Increased toxicity: Probenecid (decreases renal excretion of nitrofurantoin); anticholinergic drugs increase absorption of nitrofurantoin.
      • Interaction with Food

        Information not available.
      • Interaction with Disease

        • Use with caution in patients with G-6-PD deficiency, patients with anemia, vitamin B deficiency, diabetes mellitus or electrolyte abnormalities.
        • Therapeutic concentrations of nitrofurantoin are not attained in urine of patients with Clcr <40 mL/minute (elderly).
        • Use with caution if prolonged therapy is anticipated due to possible pulmonary toxicity.
        • Acute, subacute, or chronic (usually after 6 months of therapy) pulmonary reactions have been observed in patients treated with nitrofurantoin.
        • If these occur, discontinue therapy; monitor closely for:
          1. Malaise,
          2. Dyspnea,
          3. Cough,
          4. Fever,
          5. Radiologic evidence of diffuse interstitial pneumonitis or fibrosis.

      FAQs about Macfuran 100 MG Capsule

      • Ques : What is Macfuran 100 MG Capsule?

        Ans : Macfuran 100 MG Capsule is administered to cure UTIs caused by a few typical kinds of bacteria. Lung inflammation is one of the major but very rare side effects of Macfuran 100 MG Capsule and usually occurs if the usage persists for more than half a year.

      • Ques : What are the uses of Macfuran 100 MG Capsule?

        Ans : Macfuran 100 MG Capsule used for the treatment of Urinary Tract Infection.

      • Ques : What are the side effect of this Macfuran 100 MG Capsule?

        Ans : Possible side effects of this tablet are as follows:

        • Chest Pain
        • Chills
        • Fever
        • Fatigue
        • Drowsiness

      • Ques : How long do I need to use Macfuran 100 MG Capsule before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Macfuran 100 MG Capsule?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      • Ques : Should I use Macfuran 100 MG Capsule empty stomach, before food or after food?

        Ans : This medication should be taken after food in a prescribed dosage.

      • Ques : What are the instructions for the storage and disposal of Macfuran 100 MG Capsule?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      • Ques : How is this Macfuran 100 MG Capsule administered?

        Ans : This medication is administered orally.

      References

      • Nitrofurantoin-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/nitrofurantoin

      • Nitrofurantoin-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 7 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00698

      • NITROFURANTOIN tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=NITROFURANTOIN

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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