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Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. These abnormal cells do not carry out the functions of normal lung cells and do not develop into healthy lung tissue. As they grow, the abnormal cells can form tumors and interfere with the functioning of the lung, which provides oxygen to the body via the blood.
Lung cancer is the most common cause of death due to cancer in both men and women throughout the world. According to the U.S. National Cancer Institute, approximately one out of every 14 men and women in the U.S. is diagnosed with cancer of the lung at some point in their lifetime. Lung cancer is predominantly a disease of the elderly; almost 70% of people diagnosed with lung cancer are over 65 years of age, while less than 3% of lung cancers occur in people under 45 years of age.
What Causes Lung Cancer?
The development of lung cancer is strongly associated with cigarette smoking, approximately 90% of lung cancers are attributable to use of tobacco. Pipe and cigar smoking can also cause lung cancer, but the risk is not as high as with cigarette smoking. Tobacco smoke contains more than 4,000 chemical compounds, many of which are cancer causing (carcinogens). Passive smoking, i.e. the inhalation of tobacco smoke by non-smokers who live or work with smokers, is also an established risk factor for the development of lung cancer.
Genetic susceptibility (i.e. family history) may play a role in the development of lung cancer. Other causes of lung cancer include air pollution (from vehicles, industry, and power generation) and inhalation of asbestos fibres (usually in the workplace).
Lung Cancer Symptoms:
Early symptoms and signs of lung cancer:
There may be no symptoms at the onset of the disease. When present, common symptoms of lung cancer may include:
- Coughing: This includes a persistent cough that doesn't go away or changes to a chronic smoker's cough, such as more coughing or pain.
- Coughing up blood: Coughing up blood or rust-colored sputum (spit or phlegm) should always be discussed with your doctor.
- Breathing Difficulties: Shortness of breath, wheezing or noisy breathing (called stridor) may all be signs of lung cancer.
- Loss of Appetite: Many cancers cause changes in appetite, which may lead to unintended weight loss.
- Fatigue: It is common to feel weak or excessively tired.
- Recurring infections: Recurring infections, like bronchitis or pneumonia, may be one of the signs of lung cancer.
Signs of advanced stages of lung cancer: Advanced stages of lung cancer are often characterized by the spread of cancer to distant sites in the body. This may affect the bones, liver or brain. As other parts of the body are affected, new lung cancer symptoms may develop, including:
- Bone pain
- Swelling of the face, arms or neck
- Headaches, dizziness or limbs that become weak or numb
- Lumps in the neck or collar-bone region
Treatment: Treatment for cancer involves a combination of surgery to remove cancer cells, chemotherapy and radiation therapy to kill cancer cells. Lung cancer is incurable unless complete surgical removal of the tumour cells can be achieved. Surgery is the most effective treatment for lung cancer, but only a few percentage of lung cancers are suitable for surgery i.e. Stage I and II NSCLC and cancer that has not spread beyond the lung.
Radiation therapy may be used for both NSCLC and SCLC and is a good option for people who are not suitable for surgery or who refuse surgery. Chemotherapy is used for both NSCLC and SCLC. Chemotherapy drugs may be given alone or in combination with surgery or radiation therapy. Chemotherapy is the treatment of first choice for SCLC since it has usually spread extensively in the body by the time it has been diagnosed.
Also used in the treatment of lung cancer are targeted therapies. These are drugs (gefitinib and erlotinib) or antibodies (cetuximab, bevacizumab) that block the growth and spread of cancer by interfering with specific molecules involved in tumor growth and progression. They are used in some patients with NSCLC that does not respond to standard chemotherapy.
Sir, What is the meaning of at L4-L5, L5-S1 Level? There is Diffuse disc bulge, causing bilateral moderate neural foramina narrowing Abutting Exiting nerve Roots, and also tell me about is this any serious or anything.
The uterus is a muscular structure held in place inside your pelvis with the help of muscles, ligaments, and tissues. These muscles weaken in women due to pregnancy, childbirth or delivery complications and can lead to severe complications. One such complication is a uterine prolapse. Uterine prolapse occurs when the uterus sags or slips from its normal position into the vaginal canal.
The causes of uterine prolapse are varied and include:
- Delivering a large baby
- Difficulty in labor and delivery
- Reduction in estrogen levels post menopause
- Traumatic childbirth
- Loss or weakening of the pelvic muscle
- Conditions which lead to increased pressure in the abdominal area such as a chronic cough, straining, pelvic tumors or accumulation of fluid in the abdomen
- Loss of external support due to major surgery in pelvic area
Uterine prolapse can be complete or incomplete depending on how far the uterus sags into the vagina. Women who have minor uterine prolapse may not have any visible symptoms. However, if the condition worsens, it manifests itself in visible signs.
Symptoms of moderate or severe prolapse are:
1. A feeling of fullness or pressure in your pelvis when you sit
2. Seeing the uterus or cervix coming out of the vagina
3. Vaginal bleeding or increased discharge
4. Painful sexual intercourse
5. Recurrent bladder infections
6. Continuing back pain with difficulty in walking, urinating and moving your bowels
Without proper attention, the condition can cause impairments in the bowel, and can also affect bladder and sexual function. If you wish to discuss about any specific problem, you can consult a Gynaecologist.
I have back pain L4. L5 problem fast in 5 years. I want to reduce pain with out operation is possible. Please Inform
Detecting a lump on your breasts can be stressful for any women. Breast cancer is a common type of cancer and is said to affect primarily affect women though 1% of breast cancer cases affect men. Breast cancer can be categorized into different types based on their capability to affect surrounding tissues.
The most common amongst these are:
- Ductal carcinoma in situ
- Invasive ductal carcinoma
- Invasive lobular carcinoma
Breast cancer is caused by mutations of a person’s DNA cells. This could be inherited from one’s parents or acquired by an unhealthy lifestyle. These DNA mutations cause cells in the breast tissue to multiply rapidly and turn cancerous. The risk factors for breast cancer can be categorized as modifiable and non-modifiable.
Modifiable risk factors:
- Excessive alcohol consumption
- Use of combined hormone therapy after menopause
- Lack of exercise
Non-modifiable risk factors:
- Family Medical History
- Personal Medical History
- Atypical hyperplasia
- Early start of menstruation cycle
- Presence of dense breast tissue
- Inherited genetic mutations
As with any other type of cancer, the earlier it is diagnosed, the easier it is to treat. In its early stages, breast cancer is not painful and has negligible symptoms. In most cases, it is detected only by finding a lump on the breast or through a mammography. This lump may also be present in the armpit or above the collar bone. Some of the other symptoms of breast cancer include:
- Nipple inversion
- Discharge from the nipples
- Changes in the colour and texture of skin covering the breast
Breast cancer has five stages beginning from 0 and going up to 4. This is based on the size of the tumour, involvement of lymph nodes and whether or not metastasis has occurred.
- Stage 0: At this stage, the tumour does not affect the lymph nodes and has not metastasized. Thus at this stage, it is noninvasive.
- Stage I: In this case the tumour is smaller than 2 cm in diameter and has not spread to any of the surrounding tissues.
- Stage II: In this stage, the cancerous tumours are still fairly small in size but also affect the surrounding lymph nodes.
- Stage III: These tumours are larger than 5 cm in diameter and involve the lymph nodes to a greater extent.
- Stage IV: This is also known as metastatic breast cancer. In this stage, the cancer cells metastasize to other parts of the body.
Surgery is the most preferred form of treatment for breast cancer. This may be combined with radiation, chemotherapy, targeted therapy or hormone therapy depending on the stage and type of cancer, the patient's overall health, age and personal preferences. In case you have a concern or query you can always consult an expert & get answers to your questions!
I have a slip disc problem month ago. Now the pain has gone ,but there some stretch in my leg and I also feel less strength like I have before the episode .so now I planning to go for a gym for aerobic exercise and cycling because I feel to loss my wait. Therefore please answer that I can go for gym, swimming,or cycling or not?
Breast cancer is a type of cancer which occurs due to the development of cancerous cells in a person's breasts. Women are usually affected by breast cancer and breast cancer is one of the most common forms of cancer after skin cancer. Usually fatal if not diagnosed in its early stage, breast cancer is a very serious medical ailment. Read on more to find all about the different symptoms, causes, preventive measures and treatment of breast cancer.
Breast cancer has a few distinct characteristics and if you have a few or all the following symptoms you could be more likely to suffer from breast cancer.
a) The formation of a lump in your breast which is different from the surrounding tissue and usually more thickened.
b) The discharge of bloody fluid material from the nipples.
c) Sudden change of the size, shape and appearance of the breast.
d) Certain distinct changes to the skin over the breast for example an indentation in the skin similar to that of a dimple.
e) Appearance of an extra nipple which is inverted.
f) If the darkened area around the nipples known as the areola is flaking or peeling off.
Studies and researches remain inconclusive on what causes breast cancer. Breast cancer occurs due to abnormal division of the cells located in the breast which over time accumulate and form lumps. They
might spread to other parts of the body. Breast cancer is caused mainly due to a complex interaction of personal genetics, environment and lifestyle choices. Breast cancer can also be caused due to genetics as about 5% to 10% of cases are due to gene mutations which pass onto generations.
3. Risk factors
There are certain factors which increase the probability of contracting breast cancer. Increasing age, personal and family history of breast cancer, obesity, radiation exposure, pregnancy at an older age, post-menopausal hormone therapy are some of the factors that increase the chances of breast cancer.
Several forms of surgical methods exist to treat breast cancer. Depending on the condition and spread of the disease a suitable surgery is performed. These include mastectomy, lumpectomy, axillary lymph node dissection and removal of both breasts. Other forms of treatment include chemotherapy or the use of high doses of drugs to destroy cancerous cells. Radiation therapy where X-rays are used to destroy the cancer cells is also effective.
In case you have a concern or query you can always consult an expert & get answers to your questions!
Bone cancer is a cancerous tumour in the bone, destroying the normal bone tissues. Tumours on bone tissues are not always cancerous or malignant, they are mostly benign. Primary bone cancer is when the malignant tumour begins to form in the tissues of the bones, but when these cancerous cells spread to other body parts like breasts, prostate or lungs, it is called metastatic cancer. Primary bone cancer is less common than metastatic cancer.
Bone cancer can be of three different types:
Osteosarcoma: In this case, the malignant tumour arises from the osteoid bone tissue. This occurs mainly in the upper arm and knee areas.
Chondrosarcoma: In this case the cancerous cells form in the cartilaginous tissues, causing a lot of pain. This occurs mostly in the pelvic area.
The Ewing sarcoma generally arises in the bone but it can also form in the soft tissues. Other kinds of soft tissues affecting cancerous cells are known as soft tissue sarcomas.
There aren’t many clear defined causes; however, several factors have been identified by researchers.
Osteosarcoma is seen to occur more frequently in people who have been through a high external radiation therapy dose.
In people who have frequently been treated with anticancer medications, children tend to be most affected.
Heredity may be an adding cause, although the percentage of hereditary transfer of cancer cells is very low.
People with hereditary bone defects or implants have a higher chance of acquiring bone cancer.
The most common and saddening symptom of bone cancer is painful, although not all bone cancers cause pain. Unusual or persistent swelling or pain around a bone maybe a red flag for bone cancer. In case of a situation like this, immediate doctor’s opinion is required.
Usually, diagnosis of a bone cancer can be made using X-rays; for example, a bone scan, a computed tomography scan, a magnetic imaging procedure—positron emission tomography, and an angiogram. Biopsy and blood tests are also helpful in bone cancer diagnosis.
The size, location and stage of cancer, age, and health of the person decide the kind of treatment that should be given to the patient. Various treatment options include chemotherapy, radiation therapy and cryosurgery.
The combined survival rate of all sorts of bone cancers is 70%. This percentage may vary with the type of bone cancer and also its stage.
In case you have a concern or query you can always consult an expert & get answers to your questions!
One of the things that Shannen Doherty and Rita Wilson, the wife of Tom Hanks, have in common, apart from their fame is that both were affected by breast cancer. No matter how normal a person may seem, breast cancer can strike anyone. In fact, it usually strikes one in eight women. So, it makes good sense to know what it can appear as!
Breast cancer makes up a rather big amount of the general cancer cases as 15% of the cancer cases which are reported on a yearly basis are usually breast cancer cases. That being said, there are quite a few things which can be done in order to reduce a person’s risk to breast cancer.
Effective ways to prevent breast cancer-
As with any other types of cancer, breast cancer is a condition characterized by uncontrolled and rapid cell proliferation and division in the breast, resulting in the formation of a malignant tumor. While breast cancer is known to be one of the most common types of cancer affecting women, men are also susceptible to the condition.
An early diagnosis of the condition gives a mercurial boost to the treatment for breast cancer, often ensuring a full recovery. Unfortunately, in most cases, breast cancer gets diagnosed at a later stage. Some of the symptoms commonly associated with breast cancer include:
- A change in the breast shape, size, or even the contour.
- The appearance of a lump in the breast, often pea sized.
- There may be a fluid discharge (can be clear or blood-stained) from the nipples. In addition to this, the skin around the nipples or the breast may undergo some change. It may appear red, inflamed, scaly or even puckered and dimpled.
In addition to the medications and treatment, a person with breast cancer can benefit by practicing the following tips diligently:
- Self-awareness: Nobody can know your body better than yourself. The associated complications of breast cancer can be averted if only people stop overlooking the early signs and symptoms. There are many government sponsored campaigns and programs to create awareness about breast cancer. Once a while, self-examine your breasts. Feel your breasts for any lumps or thickenings. If you notice any abnormalities, waste no time and consult a doctor at the earliest.
- BRCA1 and BRCA2 human genes: The BRCA1 and BRCA2 genes are important with regards to the breast cancer. These genes are responsible for the production of tumor suppressor proteins, which play a pivotal role in the repair of DNA damage (often resulting from mutations or diseases). A mutation (often genetically triggered or hereditary trait) in BRCA1 and BRCA2 genes can wreak havoc, elevating the instances of breast cancer and many other types of cancer (ovarian cancer, prostate cancer, acute myeloid leukemia, and pancreatic cancer, to name a few). Thus, people who have a family history of breast cancer triggered by a mutation in BRCA1 and BRCA2 genes should get themselves tested as a precautionary measure.
- Obesity is a big No: Maintaining a healthy body weight is the need of the hour. Various research has found a link between obesity and increased risk of breast cancer. According to the American Cancer Society Cancer Prevention Study-II, women who put on extra weight (60 pounds or more) after the age of 18, are at a greater risk of developing breast cancer post-menopause as compared to their healthy counterparts. Thus, it is important to keep the body weight within healthy limits. Take care of your diet. Indulge in physical activities and exercise.
- Avoid excessive alcohol consumption: People, particularly women who consume alcohol in excess (2-6 drinks daily) are at an increased risk of breast cancer. Limit your daily dose of alcohol (1 drink or less per day).
Prevention is Prudent-
Get Fit: The first thing which should be done is that a reasonable level of fitness should be maintained. Many studies have found that if a person is significantly heavier than her recommended weight, she is at a far great risk to develop all sorts of cancer and breast cancer, in particular, than a person who is able to keep her weight in check. The difference in cancer risk rates is about 40%. This is because a greater amount of fat leads to more estrogen being produced, which increases the risk of breast cancer.
Quit Smoking: While most people associate smoking as something which increases the risk of cancer to the lungs and are not aware that it increases the risk of breast cancer, too. So, the best solution is to kick the habit!
Get Off the Pill: Once a woman crosses past her mid-thirties, she should try to avoid relying on birth control pills to reduce the risk of pregnancy. This is because these pills have an effect which increases the risk of breast cancer, which heightens as a woman gets older. As long as the woman cuts out the use of the pill, the risk quickly gets cut, as well.
Get Regular Check Ups: While screening for breast cancer by making use of mammograms does not cut the risk of it, the screening helps detect breast cancer early if it does exist. As a result, a woman has a much better chance of fighting breast cancer. So, a woman who is past the age of forty should try to have a mammogram on an annual basis with the frequency of the same increasing as she gets older. However, it is to be kept in mind that going for a mammogram too often is also not a good idea as the tests themselves pose risks of DNA changes.
Women all around the world are susceptible to breast cancer. While there isn’t a 100% chance of avoiding it, taking care of yourself and leading a fit and active lifestyle can significantly cut down your risk of contracting this condition. Remember, your health is in your hands, so the earlier you start, the better!
In case you have a concern or query you can always consult an expert & get answers to your questions!
The most powerful and amazing organ in our body is the brain. It differs from many other organs of our body not only by its shape, but also by its special type of cell called neurons. When these cells gets affected or dead it can never be reverted or regenerated which is the most exclusive nature found only in brain cells. The cells in other parts of our body has the capacity to regenerate (can be replaced or new one can be grown or produced), but brain cells are exception. Hence any damage to the brain, injury or trauma is really a crucial thing to be considered with utmost care.
Brain surgeries really need skill, proper training, confidence and intelligence to perform this highly complicated and risky surgery.
Brain surgeries are performed to:
- Remove the brain tissues that are grown abnormally
- Aneurysm is clipped to prevent flow of blood cliff off an aneurysm
- Biopsy purpose or to remove the tumour
- Make a nerve free
- Drain the abnormal blood or clot collection or to drain any excessive fluid collection caused by infection.
- To implant artificial electronic device as a treatment for conditions like Parkinson's disease
- Biopsy: A part of brain tissue is removed for the brain or whole tumour is removed.
- Craniotomy: The skull bone is opened to remove tumour, an aneurysm and drain fluid or blood from infection.
- Minimally invasive endonasal endoscopic surgery: Endoscopic devices are inserted through the nose to remove the lesions or tumour.
- Minimally invasive neuroendoscopy: Similar to endonasal surgery but small incision is made.
- Anaesthesia risks like breathing difficulty, allergic reaction to medications, excessive bleeding or clots and infection.
- Risk related to the brain surgeries are seizures, coma, swelling of brain, infection to brain or meanings, surgical wound infection that intrudes to the brain structures, abnormal clot formation and bleeding.
- General risks include muscle weakness, disturbances in memory, speech, vision, coordination, balance and other functions that are controlled by the brain.