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Trofentyl 50Mcg Injection

Manufacturer: Troikaa Pharmaceuticals Ltd
Medicine composition: Fentanyl
Prescription vs.OTC: Prescription by Doctor required

Trofentyl 50Mcg Injection is a synthetic opioid medication. It is used in combination with anesthesia to prevent post-surgery pain or other medical procedures that may prove to be painful.

On using Trofentyl 50Mcg Injection you may experience side effects such as nausea, vomiting, respiratory issues, fever and diaphoresis. If the allergic reactions persist or become worse over time contact your health care provider right away.

Do not use Trofentyl 50Mcg Injection if you are allergic to any of the ingredients contained in it, if you are already taking any other prescription or non-prescription drugs, if you have just had a surgery, you have liver/kidney/lung/ mental/mood problems, you have breathing problems, you are allergic to any foods, substances or medicines, you are pregnant, or are planning to become pregnant or breastfeeding a baby, you have alcohol withdrawal syndrome, have low blood pressure, are overweight at present.

The dosage for Trofentyl 50Mcg Injection should ideally be prescribed by your doctor. The usual dose in adults is about 100 mcg for the tablet and spray which needs to be taken sublingually. The dose for the transmucosal lozenge is about 200 mcg.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Internal Medicine Specialist before using this medicine.

In addition to its intended effect, Trofentyl 50Mcg Injection may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Is It safe with alcohol?
No interaction found
Are there any pregnancy warnings?
Durogesic 50mcg patch may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Are there any breast-feeding warnings?
Unknown. Human and animal studies are not available. Please consult your doctor.
Is it safe to drive while on this medicine?
Caution is advised when driving or operating machinery.
Does this affect kidney function?
Caution should be used in patients with renal impairment.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Below is the list of medicines, which have the same composition, strength and form as Trofentyl 50Mcg Injection , and hence can be used as its substitute.
Neon Laboratories Ltd
Are there any missed dose instructions?
If you miss a dose of Fentanyl, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Trofentyl 50Mcg Injection is depressant drug that is used for anesthetic and analgesia purposes. It belongs to a class of drugs known as opioid that makes it useful in chronic pain management. It works by binding itself to mu-receptor in the central nervous system that results in low intracellular cAMP and reduction in the release of neurotransmitters
What are you using Trofentyl 50Mcg Injection for?
How much was the improvement?
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

Hey. Since last year I've been suffering from short memory. I've been taking tablets (omega3 and Himalaya mentat) but what is the reason for me having short memory? It is affecting me because I am a student and sometimes I do not have the money to continuously buy tablets! I don't mind buying them but can I at least know the reasons why this is happening?

MBBS, MD - Psychiatry, MBA (Healthcare)
Psychiatrist, Davanagere
Hey. Since last year I've been suffering from short memory. I've been taking tablets (omega3 and Himalaya mentat) but...
Age related memory loss As everyone gets older it becomes more difficult to remember things, especially if one is getting over 60 years of age. This is because like other parts of the body, the brain also changes with age. How? Here’s how. Parts of the brain that handle cognitive functions, learning, memory, and planning shrink with age. Neurons (nerve cells) in the brain stop communicating efficiently. This is of course a gradual process. Arteries narrow with age and new blood vessels stop forming, so less blood reaches the brain thus slowing down its activity. Plaques may form that block communication between the neurons. Inflammation in the brain increases. Damage by free radicals increase as the brain ages. However, recent studies have indicated that the aging brain actually improves in certain areas such as vocabulary and other verbal forms. Another interesting finding is that the brain continues to develop new neurons even late in life. So essential communications can still be maintained through these neurons. Mild cognitive impairment Other common causes of memory loss include – Depression: Some people with depression may have slowed down thinking and mental abilities. Other symptoms could be – Low mood most of the time, irritability Insomnia Poor appetite Difficulty with affection Loss of interest in life, poor motivation, sadness, guilt Tiredness Medication: Certain medication too could cause memory loss or forgetfulness. This condition however improves once the medication is stopped. Anti-anxiety drugs – Alprazolam, diazepam, temazepam, chlordiazepoxide, etc. Cholesterol lowering drugs (Statins) – Atorvastatin, lovastatin, fluvastatin, etc. Antiseizure drugs – Acetazolamide, carbamazepine, ezogabine, gabapentin, etc. Antidepressants – Amitriptyline, clomipramine, doxepin, imipramine, etc. Painkillers – Fentanyl, hydrocodone, morphine, oxycodone, etc. Hypertension drugs – Beta blockers such as atenolol, carvedilol, metoprolol, propranolol, etc. Sleeping aids – Eszopiclone, zaleplon, etc. Dopamine agonists to treat Parkinson’s disease, certain pituitary tumors, and sometimes restless legs syndrome. Antihistamines – Brompheniramine, carbinoxamine, chlorpheniramine, clemastine, etc. Incontinence drugs – Oxybutynin (Oxytrol), darifenacin, etc. Medical conditions: Certain medical conditions can directly affect the way brain functions. Some of these conditions are – Stress and anxiety Underactive thyroid, in which the thyroid gland does not produce sufficient hormones Subarachnoid haemorrhage, that is, bleeding in the brain Vitamin B1 or thiamine deficiency Transient global amnesia in which there is a sudden episode of memory loss that cannot be recalled afterwards Brain tumour Alcohol misuse Dementia and the various types of dementia Dementia is perhaps the most severe of the memory problems that affects your daily life. It usually occurs in people who are over 65 years of age. Dementia is actually not a disease but a syndrome that consists of loss of functions involving memory, thinking speed and reasoning. Symptoms of dementia include – Forgetting recent events Difficulty remembering names and places Asking questions repetitively Becoming confused in unfamiliar environments Difficulty planning and organizing Difficulty in verbal skills Changes in personality and mood Depression Dementia can be caused by all the above mentioned causes plus 60 different illness, but the primary and most common cause is the Alzheimer’s disease which account for 50 to 60 percent of dementia cases. I hope this helps.
2 people found this helpful

Mere menses cycle miss huye to maine urine test kiya to usme 1line dark pink thi our 2 line usse fent pink thi. Our 6 day jada huye hai. Aur aj achank muje 1 bund white bliding hua. To isse koi problem ho sakati hai kya. Our mujhe ulti bhi ho rahi hai 2 days se.

Homeopath, Gurgaon
Mere menses cycle miss huye to maine urine test kiya to usme 1line dark pink thi our 2 line usse fent pink thi. Our 6...
Get your preg test done again in a lab for confirmation of preg. If it is positive then take precautions accordingly. Slight white discharge is ok but if it increases then consult a gynae doctor.

Hi. I have a problem. I have too much headache when I went for out in sun. please suggest me some medicine to get rid from it. Sometime I fent down due it.

Homeopath, Faridabad
Hi. I have a problem. I have too much headache when I went for out in sun. please suggest me some medicine to get rid...
Hello, take natrum mur 200 ch, 5 drops, single dose. Glonoine 30 ch, 3 drops twice daily. Bc no. 12, 6 tabs twice daily. Revert me after 7 days.

Hello sir I am 14 year old. I have a lot of problems related to my health as extra slim body, weight loss, and some time my body begins to twist and fent too. Please suggest me home remedies.

DHMS (Hons.)
Homeopath, Patna
Hello sir
I am 14 year old. I have a lot of problems related to my health as extra slim body, weight loss, and some t...
Hello, U are under wt by26 kg. * Take butter with toast/ bread in the breakfast. * take, banana with warm milk in the moring. * Your lunch should be rich with ghee. * take, apple, carrots, mango,papaya,soybeen, rajma, pulses, almond,walnut, cheese, milk. * Take, plenty of water to eliminate toxins. * go for meditation for 30 mnts. ** Homoeo-medicine** @ Ashawagandha Q-10 drops,thrice with little water. @ Five phos 6x-4 tabs, thrice a day. @Alfalfa Q-10 drops,thrice a day with little water . Report your progress,fortnightly. Take, care and b healthy.
1 person found this helpful

Popular Health Tips

Can Opioids Discourage an Erect Penis?

MD - General Medicine
Sexologist, Delhi
Can Opioids Discourage an Erect Penis?

Opioids have been in the news in recent months, largely due to an increasing concern about abuse of these drugs and the health crisis that is forming as a result of that abuse. There are many reasons to be concerned about improper use of opioids, and penis health might be one of those reasons. Some research suggests that use of opioids may cause issues with getting or maintaining an erect penis.


Many people have heard of opioids, but what are they exactly? The National Institute on Drug Abuse defines opioids as a class of drugs that interact with opioid receptors on nerve cells in the body and brain. This class of drug is infamous because it includes the illegal drug heroin. It also includes a synthetic opioid called fentanyl, which is used to relieve pain but which is also a "street drug" under names like Apache, Jackpot, and China White. There are many other opioid pain relievers, like morphine, codeine, and oxycodone.

Opioids used for pain relief serve a very important medical function: enabling patients enduring extremely painful procedures or conditions to cope with pain. Unfortunately, even some of the prescription opioids have in recent years become abused. Combined with the presence of heroin and the fentanyl derivatives, opioid addiction has expanded dangerously. More than 90 Americans die every day from abuse of opioids in their various forms.

Erect penis problems

  • There exists the possibility that opioid use - even when prescribed and used in an appropriate manner - may have an impact on a man's erect penis function.
  • A recent study from the Journal of Sexual Medicine reviewed ten studies that looked at opioid use and erectile dysfunction in men. The ten studies involved a total of more than 8,000 men (average age of 41.6 years). The studies looked at men who were receiving opioid management, and compared them to controls that received placebos.
  • After analyzing the results from all ten trials, the authors determined that men who use opioids have a 96% greater risk of developing erectile dysfunction. Not only that, but the risk was even greater among younger men. (Men may typically develop some erect penis issues as they age; younger opioid users were much likelier to develop them earlier than the typical population.)
  • Some studies found that opioids lower testosterone levels, which may be a reason why erectile dysfunction may develop. Other theories (yet to be tested in men using opioids) are that depression may play a role, or that opioids could negatively decrease nitric oxide production. Nitric oxide is needed to help penile blood vessels expand and accommodate the greater influx of blood that creates erections.
  • While this study presents some interesting ideas, it points to the need for more studies designed to specifically address erect penis issues and opioids and which can look more closely into possible causes and effects.
  • In the meantime, if a man is prescribed opioids, he may want to report any erectile dysfunction issues he experiences to his doctor and discuss possible options. (And any man who is abusing opioids is strongly encouraged to seek help from a medical professional immediately; such abuse can be fatal.)
  • Opioids and their possible effect on an erect penis are just one factor to consider when protecting penis health. Daily use of a top drawer penis health crème (health professionals recommend Man1 Man Oil, which is clinically proven mild and safe for skin) is an excellent way to help maintain that overall health. Definitely seek out a crème with L-arginine, an amino acid which boosts nitric oxide production, thereby helping penile blood vessels expand as needed. It also helps if the crème contains vitamin D, the "miracle vitamin" that the body needs to help maintain its health, especially during cold winter months.
1 person found this helpful

Chronic Pain - Ways You Can Cope With It!

Pain Management Specialist, Navi Mumbai
Chronic Pain - Ways You Can Cope With It!

There are numerous people worldwide who suffer from chronic pain. The experience can be quite annoying and painful, not only for the affected person but also for their loved ones and family members. Coping with the situation can be quite a challenge. Chronic pain can leave a person physically as well as emotionally exhausted. Thus, proper management is needed to deal with the situation better.

Causes of chronic pain
Chronic pain can be due to numerous reasons such as

  1. Use of wrong footwear (especially high heels in case of women).
  2. Injury due to rigorous and strenuous exercise.
  3. Unhealthy lifestyle habits, poor posture.
  4. Chronic pain can also result from a traumatic injury.
  5. Medical conditions such as Fibromyalgia (a condition characterized by muscular pain, especially in the shoulder and neck region), AIDS, Cancer, Arthritis (Osteoarthritis and Rheumatoid Arthritis), Multiple sclerosis, to name a few, can give rise to chronic pain. Obese people are at a greater risk of suffering from chronic pain.
  6. In some people, incorrect sleeping posture and the wrong choice of sleeping mattress can cause chronic pain.
  7. With age, a person is likely to suffer from chronic pain (age related problems and disorders).

The effectiveness of the treatment depends on the severity as well as the factors responsible for the chronic pain.

  1. Medications such as NSAID (Nonsteroidal Anti-Inflammatory Drugs), Tylenol, provide relief in case the pain is not very severe.
  2. In severe cases, doctors may recommend the use of corticosteroid injection as well as powerful painkillers such as Fentanyl, Lortab or Roxicet.
  3. Certain antidepressants and antianxiety drugs such as Duloxetine and Valium respectively may also be used to improve the condition.
  4. Physiotherapy and Bioelectric therapy (the bioelectric therapy works by blocking the pain messages or signals to the brain, thereby relieving the pain) also bear fruitful results.

In addition to the above treatment and medications, certain changes and modifications in lifestyle habits can also help to cope with the chronic pain better.

  1. People with chronic pain should avoid stress, anxiety, and depression as much as they can. These are nemesis that can aggravate the pain further. Meditation, yoga, breathing exercise, are great stress busters and mood enhancers.
  2. Obesity is one of the underlying factors responsible for chronic pain. Maintain a healthy body weight. Eat healthy and nutritious diet, exercise regularly (even if it is only for 30 minutes). For obese people with chronic pain, rigorous exercise can prove to be harmful. Indulge in light to moderate exercise. Seek an expert help if necessary.
  3. Do not compromise on your sleep. Sound sleep can work wonders for the chronic pain. Follow a healthy sleeping routine.
  4. Refrain from smoking and drinking. These can make the situation worse.
  5. Gentle massages can help relieve the pain to some extent. Again, it is advised to seek an expert guidance.
  6. Alternate medications like Chiropractic and Acupuncture have helped many patients with chronic pain.
  7. Avoid doing very strenuous physical activities.
  8. Join a support group. You will not only feel better but will also be able to deal with the situation better.

In case you have a concern or query you can always consult an expert & get answers to your questions!

4194 people found this helpful

Pain Management During Cancer- An Inherent Part Of The Treatment!

MBBS, MD - Oncology, DNB - Super Speciality, Immuno Oncology
Oncologist, Delhi
Pain Management During Cancer- An Inherent Part Of The Treatment!

With every passing day, there are new advancements in the field of medicine, and cancer care is no exception either. A condition that still frightens the mass has come a long way in terms of cure and management. Cancer is life threatening but when diagnosed in the early stages, can be cured with proper medical intervention.

Many cancer patients experience pain which is caused as a result of the disease or as the result of the treatments for cancer. When the cancer spreads or the malignant tumor increases in size, it puts pressure on the surrounding (bones, tissues, etc.) which intrigues the pain. The cancer treatments like chemotherapy, radiation therapy, and surgery may also cause pain in the patients.

Here is an account on managing pain during cancer.

Treatment for Cancer Pain
Cancer pain can be dull, sharp, or achy. It can be constant or intermittent and can be mild, severe, or moderate. There are several over-the-counter or prescription medicines available in the market which can reduce the pain caused by the growing tissues or the treatments/therapies. A few such pain relievers include aspirin, acetaminophen, and ibuprofen.

Treatment According to Severity
For pain which is mild or moderate, you can opt for Non-opioids which are anti-inflammatory medicines and can be bought without the prescription from the drug counters. If you are having moderate to severe symptoms of pain, then you may be prescribed opioids like hydromorphone, hydrocodone, fentanyl, etc.

For burning and tingling sensation, antidepressants like imipramine or the trazodone, etc., can provide relief. You must not confuse antidepressant with medicines for depression; these are for pain management as well. You can also opt for the antiepileptics drugs which can reduce the burning or tingling sensation of cancer and have it doesn’t refer that you get seizures. If there is swelling, then steroids are the option for you to control the swelling and the pain caused from it.

Ways to Take Medicines for Cancer Pain
Most of the medications that your doctor would prescribe you have to be taken orally if not directed otherwise. The medications are usually in the pills form. If the patient, for any reason, is not able to take the drugs orally, then he/she may have to take them as rectal suppositories and even transdermal patches.

It can also be injected into your body through an intravenous opening in which the needle with the medicine is inserted directly into the veins. There is also a subcutaneous process where the medicine is injected with a small needle just under the first layer of your skin.

Studies report that often cancer pain is under-treated. A common reason is the reluctance of the patients to speak about the pain. Other reasons for not opting for pain medications are the fear of addiction and side-effects.

Cancer pain management is indeed an important part of the cancer treatment, and the goal is to manage the pain at a bearable level. And, the best part is that the goal is often achieved. Consult an Expert & get answers to your questions!

4221 people found this helpful

Table of Content

About Trofentyl 50Mcg Injection
When is Trofentyl 50Mcg Injection prescribed?
What are the side effects of Trofentyl 50Mcg Injection ?
Key highlights of Trofentyl 50Mcg Injection
What are the substitutes for Trofentyl 50Mcg Injection ?
What are the dosage instructions?
How does medicine works?