Acid Reflux and Oesophagitis Heartburn
Acid Reflux and heartburn are a very common problem faced by many of us. And so I decided to discuss in a very simplified way.
Let us understand the oesophagus and stomach first
When we eat, food passes down the gullet (oesophagus) into the stomach. Cells in the lining of the stomach make acid and other chemicals which help to digest food. Stomach cells also make mucus which protects them from damage from the acid. The cells lining the oesophagus are different and have little protection from acid.
There is a circular band of muscle (a sphincter) at the junction between the oesophagus and stomach. This relaxes to allow food down but then normally tightens up and stops food and acid leaking up (refluxing) into the oesophagus. In effect, the sphincter acts like a valve.
What are Acid reflux and oesophagitis?
Acid reflux means that some acid leaks up (refluxes) into the gullet (oesophagus).
Oesophagitis means inflammation of the lining of the oesophagus. Most cases of oesophagitis are due to reflux of stomach acid which irritates the inside lining of the oesophagus.
The lining of the oesophagus can cope with a certain amount of acid. However, it is more sensitive to acid in some people. Therefore, some people develop symptoms with only a small amount of reflux. However, some people have a lot of reflux without developing oesophagitis or symptoms.
What is Gastro-oesophageal reflux disease (GORD)
This is a general term which describes the range of situations - acid reflux, with or without oesophagitis and symptoms.
What are the symptoms of acid reflux and oesophagitis?
Heartburn: this is the main symptom. This is a burning feeling which rises from the upper tummy (abdomen) or lower chest up towards the neck. (It is confusing, as it has nothing to do with the heart!)
Other common symptoms: these include pain in the upper abdomen and chest, feeling sick, an acid taste in the mouth, bloating, belching, indigestion and a burning pain when we swallow hot drinks. Like heartburn, these symptoms tend to come and go and tend to be worse after a meal.
Some other uncommon symptoms: these may occur and if they do, can make the diagnosis difficult, as these symptoms can mimic other conditions. For example A persistent cough, particularly at night, sometimes occurs. This is due to the refluxed acid irritating the windpipe (trachea). Asthma symptoms of cough and wheeze can sometimes be due to acid leaking up (reflux).
Other mouth and throat symptoms sometimes occur, such as gum problems, bad breath, sore throat, hoarseness and a feeling of a lump in the throat.
Severe chest pain develops in some cases (and may be mistaken for a heart attack).
What causes acid reflux and whom does it affect?
The circular band of muscle (sphincter) at the bottom of the gullet (oesophagus) normally prevents acid leaking up (refux). Problems occur if the sphincter does not work very well. This is common but in most cases it is not known why it does not work so well. In some cases, the pressure in the stomach rises higher than the sphincter can withstand - for example, during pregnancy, after a large meal, or when bending forward.
What are the causes of Heartburn and what are the Treatment options
Most people have heartburn at some time, perhaps after a large meal. However, about 1 adult in 3 has some heartburn every few days, and nearly 1 adult in 10 has heartburn at least once a day. In many cases it is mild and soon passes. However, it is quite common for symptoms to be frequent or severe enough to affect the quality of life. Regular heartburn is more common in smokers, pregnant women, heavy drinkers, those who are overweight and those aged between 35 and 64 years.
What tests can be done to arrive at the diagnosis?
Tests are not usually necessary if you have typical symptoms. Many people experiencing acid leaking up (refluxing) into the gullet (oesophagus) are diagnosed with 'presumed acid reflux'. In this situation, they have typical symptoms and the symptoms are eased by treatment. Tests may be advised if symptoms are severe, or do not improve with treatment, or are not typical of GORD.
Gastroscopy (endoscopy) is the common test. A thin, flexible telescope is passed down the oesophagus into the stomach. This allows a doctor to look inside. With inflammation of the lining of the oesophagus (oesophagitis), the lower part of the oesophagus looks red and inflamed. However, if it looks normal it does not rule out acid reflux. Some people are very sensitive to small amounts of acid and can have symptoms with little or no inflammation to see. Two terms that are often used after an endoscopy are:
Oesophagitis. This term is used when the oesophagus can be seen to be inflamed.
Endoscopy-negative reflux disease. This term is used when someone has typical symptoms of reflux but endoscopy is normal.A test to check the acidity inside the oesophagus may be done if the diagnosis is not clear. Other tests such as heart tracings, chest X-ray, etc, may be done to rule out other conditions if the symptoms are not typical.
What can be done to relieve with symptoms?
The following are commonly advised. However, there has been little research to prove how well these lifestyle changes help to ease reflux:
Smoking. The chemicals from cigarettes relax the circular band of muscle (sphincter) at the bottom of the gullet (oesophagus) and make acid leaking up (refluxing) more likely. Symptoms may ease if you are a smoker and stop smoking.Some foods and drinks may make reflux worse in some people. It is thought that some foods may relax the sphincter and allow more acid to rfleux. It is difcult to be certain how much foods contribute. Let common sense be your guide. If it seems that a food is causing symptoms then try avoiding it for a while to see if symptoms improve. Foods and drinks that have been suspected of making symptoms worse in some people include peppermint, tomatoes, chocolates, hot drinks, coffee and alcoholic drinks. Also, avoiding large-volume meals may help.
There are some medicines which can make symptoms worse. They may irritate the oesophagus or relax the sphincter muscle and make acid reflux more likely. The most common culprits are anti-inflammatory painkillers (such as ibuprofen or aspirin). Others include diazepam, theophylline, calcium-channel blockers (such as nifedipine) and nitrates. But this is not a complete list.
Weight. If you are overweight it puts extra pressure on the stomach and encourages acid reflux. Losing some weight may ease the symptoms.
Posture. Lying down or bending forward a lot during the day encourages reflux. Sitting hunched or wearing tight belts may put extra pressure on the stomach, which may make any reflux worse.
Bedtime. If symptoms recur most nights, the following may help: Go to bed with an empty, dry stomach. To do this, don't eat in the last three hours before bedtime and don't drink in the last two hours before bedtime.
If you are able, try raising the head of the bed by 10-20 cm (for example, putting two normal sized pillows under your head. This helps gravity to keep acid from refluxing into the oesophagus.
What are the treatments for acid reflux and oesophagitis?
Antacids are alkaline liquids or tablets that reduce the amount of acid. A dose usually gives quick relief. There are many brands which you can buy. You can also obtain some on prescription. You can use antacids 'as required' for mild or infrequent bouts of heartburn.
If you have symptoms frequently then see a doctor. An acid-suppressing medicine will usually be advised. Two groups of acid-suppressing medicines are available - proton pump inhibitors (PPIs) and histamine receptor blockers (H2 blockers). They work in different ways but both reduce (suppress) the amount of acid that the stomach makes. PPIs include omeprazole, lansoprazole, pantoprazole, rabeprazole and esomeprazole. H2 blockers include cimetidine, famotidine, nizatidine and ranitidine.
In general, a PPI is used first, as these medicines tend to work better than H2 blockers. A common initial plan is to take a full-dose course of a PPI for a month or so. This often settles symptoms down and allows any inflammation in the gullet (oesophagus) to clear. After this, all that you may need is to go back to antacids 'as required' or to take a short course of an acid-suppressing medicine 'as required.
However, some people need long-term daily acid-suppressing treatment. Without medication, their symptoms return quickly. Long-term treatment with an acid-suppressing medicine is thought to be safe and side-effects are uncommon. The aim is to take a full-dose course for a month or so to settle symptoms. After this, it is common to 'step down' the dose to the lowest dose that prevents symptoms. However, the maximum full dose taken each day is needed by some people.
If you have any question you can write down to me.
Folic acid is an important form of vitamin B which women must take during pregnancy. It is a form of man-made vitamin B known as folate. Folate plays a significant role in producing red blood cells and helps in the development of your baby’s neural tube into the brain and spinal cord, preventing any kind of birth defects in babies. Birth defects of the brain or spinal cord may occur in early stages of pregnancy. Therefore, by the time a woman discovers her pregnancy, it may become too late to prevent the defects.
How much folic acid should be taken?
A woman should start taking folic acid within the first three to four weeks of pregnancy, as birth defects may occur during this time. Women who start taking folic acid a year before getting pregnant produce healthy babies without birth defects.
400 mcg of folic acid is the recommended dose for all women who are of childbearing age and also in the first trimester of pregnancy. Multivitamins with the recommended amount of folate and folic acid supplements are generally prescribed as they help the mother deliver a healthy child. From the fourth to ninth month of pregnancy, the dose must be increased to 600 mcg.
Benefits of Folic Acid
Without sufficient folic acid in your body, the neural tube of your developing baby may not close properly. This may lead to neural tube defects, which include:
Spina bifida, a condition where the spinal cord or vertebrae develop incompletely. A baby with spina bifida may be disabled permanently.
Anencephaly, a condition that features incomplete development of the brain. Babies affected with anencephaly do not live long.
Having a sufficient supply of folic acid prevents these neural defects from developing in your baby.
Taking folic acid before and during pregnancy protects your baby against many other conditions. They include:
Folic acid also reduces the risk of developing pregnancy complications in the mother such as heart diseases, stroke, several cancers and Alzheimer’s disease.
Folic acid is naturally found in dark-green vegetables, which you must consume in abundance. Other sources of folic acid include fortified breakfast cereals, beef liver, lentils, egg noodles and great northern beans.