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IVF Cycle - Why It Is Canceled?

Dr.Deepti Nitin Gupta 87% (34ratings)
MBBS, Diploma in Obstetrics & Gynaecology, DNB (Obstetrics and Gynecology), Fellowship in Reproductive Medicine
IVF Specialist, Bhopal
IVF Cycle - Why It Is Canceled?

In vitro fertilisation (IVF) is a precarious treatment, which is filled with hope and despair in equal measures. While you cannot wait to have a baby through IVF and you are terribly excited when the IVF cycle starts with some success, you still need to be prepared to face disappointment at any stage in the cycle.

There are certain reasons why an IVF cycle can be cancelled. Some of the reasons include:

  1. Ovarian cysts: As an important part of pre-treatment in IVF, a screening is done to check for ovarian cysts. If you do have a cyst in your ovary, the date for the commencement of IVF will be pushed back. Medicines will be prescribed to reduce the cysts in such a case.
  2. Poor stimulation responses: Usually, more than three follicles in the ovaries are needed to produce eggs. Fertility drugs are given to stimulate the growth of the follicles. But sometimes, there is a poor response to the drugs and the needed number of follicles might not grow. In this case, either the IVF cycle is cancelled or a different medication is used.
  3. Hyperstimulation: On one hand, there is poor or under active response to fertility drugs and then there is hyperstimulation; which is an overactive response to the drugs. This leads to excessive growth of follicles, which causes ovarian hyperstimulation syndrome (OHS). The cycle is cancelled as OHS might cause serious problems in the womb.
  4. Decline in estradiol levels: The ovaries produce a type of estrogen called estradiol. When egg follicles grow, estradiol is secreted, which triggers the rest of the cycle. If the levels of estradiol drop, follicular development is hindered. In this case, the IVF cycle will be cancelled.
  5. Poor egg retrieval: Usually, an ultrasound is done to check the amount of mature eggs before the retrieval. Sometimes, fewer eggs are collected than what was expected. If egg retrieval is poor, the cycle will not move any further.
  6. Poor fertilization: Poor sperm or egg equality might hamper the process of fertilization, which will thus impact the development of the embryo. If the embryo does not form at all, the cycle will obviously be cancelled.
  7. Illness: If you or your partner has a high fever or fall ill anytime during the process, the IVF cycle may be abandoned.
3264 people found this helpful

Reasons Why IVF Cycle Is Cancelled

Dr.Rita Bakshi 91% (2903ratings)
MBBS, DGO, MD, Fellowship in Gynae Oncology
IVF Specialist, Delhi
Reasons Why IVF Cycle Is Cancelled

In vitro fertilisation (IVF) is a precarious treatment, which is filled with hope and despair in equal measures. While you cannot wait to have a baby through IVF and you are terribly excited when the IVF cycle starts with some success, you still need to be prepared to face disappointment at any stage in the cycle.

There are certain reasons why an IVF cycle can be cancelled. Some of the reasons include:

  1. Ovarian cysts: As an important part of pre-treatment in IVF, a screening is done to check for ovarian cysts. If you do have a cyst in your ovary, the date for the commencement of IVF will be pushed back. Medicines will be prescribed to reduce the cysts in such a case.
  2. Poor stimulation responses: Usually, more than three follicles in the ovaries are needed to produce eggs. Fertility drugs are given to stimulate the growth of the follicles. But sometimes, there is poor response to the drugs and the needed number of follicles might not grow. In this case, either the IVF cycle is cancelled or different medication is used.
  3. Hyperstimulation: On one hand, there is poor or under active response to fertility drugs and then there is hyperstimulation; which is an overactive response to the drugs. This leads to excessive growth of follicles, which causes ovarian hyperstimulation syndrome (OHS). The cycle is cancelled as OHS might cause serious problems in the womb.
  4. Decline in estradiol levels: The ovaries produce a type of estrogen called estradiol. When egg follicles grow, estradiol is secreted, which triggers the rest of the cycle. If the levels of estradiol drop, follicular development is hindered. In this case, the IVF cycle will be cancelled.
  5. Poor egg retrieval: Usually, an ultrasound is done to check the amount of mature eggs before the retrieval. Sometimes, fewer eggs are collected than what were expected. If egg retrieval is poor, the cycle will not move any further.
  6. Poor fertilization: Poor sperm or egg equality might hamper the process of fertilization, which will thus impact the development of the embryo. If the embryo does not form at all, the cycle will obviously be cancelled.
  7. Illness: If you or your partner has high fever or fall ill anytime during the process, the IVF cycle may be abandoned.

Consult an Expert & get answers to your questions!

3838 people found this helpful

Menopause - Spot the Early Signs!

Dr.Meenu Goyal 90% (638ratings)
DGO, MBBS
Gynaecologist, Delhi
Menopause - Spot the Early Signs!

Menopause is the time in a woman’s life at which she cannot procreate anymore. Side effects of pre-menopause, menopause and post menopause, shift incredibly from woman to woman. Nonetheless, normal side effects of menopause incorporate:

  1. Hot flashes
  2. Changes in eating habits
  3. Weakness
  4. Stress
  5. Tiredness
  6. Vaginal dryness and itching

The majority of the side effects connected with menopause really occur during the pre-menopause stage. A few women experience menopause with no complications or disagreeable symptoms. However, others find menopausal side effects crippling and they usually happen during pre-menopause and go on for quite a long time. The symptoms that women experience are basically identified with decreased levels of the female sex hormones estrogen and progesterone. Side effects change generally due to the many impacts that these hormones have on the female body.

Your period may not be as regularly as it used to be. You may bleed heavier or lighter than usual, and at times experience spotting. Additionally, your period might be shorter or longer in time length. In case that you do miss your period, try to rule out pregnancy. In case you are not pregnant, a missed period could show the beginning of menopause. In case you start spotting after not having your period for twelve continuous months, try to converse with your specialist to discount any genuine conditions, for example, cancer.

Symptoms of untimely menopause are frequently the same as those seen by women experiencing common menopause and may include:

  1. Unpredictable or missed periods
  2. Periods that are heavier or lighter than normal
  3. Hot flashes (a sudden warmth that spreads over the abdominal area)
  4. These symptoms are an indication that the ovaries are delivering less estrogen.
  5. Vaginal dryness (the vagina may likewise get to be distinctly more dry and less adaptable)
  6. Bladder fractiousness and increased of loss of bladder control (incontinence)
  7. Emotional changes (crabbiness, mood swings, mellow stress)
  8. Dry skin, eyes, or mouth
  9. Restlessness
  10. Diminished sex drive

Keeping in mind the symptoms recorded above, in case that you are less than forty years old and experience any of the accompanying conditions, you need to see your specialist to figure out if you are experiencing untimely menopause:

  1. You have experienced chemotherapy or radiation
  2. You or a relative has an immune system issue, for example, hypothyroidism, Graves' infection, or lupus
  3. You have unsuccessfully attempted to wind up distinctly pregnant for over a year
  4. Your mom or sister experienced untimely menopause

To analyze untimely menopause, your specialist will in all likelihood carry out a physical exam and extract blood to diagnose different conditions, for example, pregnancy and thyroid illness. He or she may likewise arrange a test to quantify your estradiol levels. Low levels of estradiol, a type of estrogen, can demonstrate that your ovaries are beginning to fall flat. At the point when estradiol levels are beneath thirty, it might show that you have early menopause. If you wish to discuss any specific problem, you can consult a gynaecologist.

5429 people found this helpful

Bleeding In IVF - Risks And Management!

MD - Obstetrtics & Gynaecology, MBBS, FNB Reproductive Medicine, MRCOG
IVF Specialist, Mumbai
Bleeding In IVF - Risks And Management!

Bleeding in IVF

IVF in layman term means test tube baby with the highest results of all assisted reproductive treatments so far.
Bleeding can happen in 30 to 40% of patients during IVF at different stages - after egg pick up, during the luteal phase and during pregnancy

Definitely bleeding generally taken with dread but it can be a good sign also and can be harmless

1. Bleeding after OPU is due to the needle prick
2. During luteal support can be due to vaginal progesterone increasing sensitivity of cervix
3. Due to blood thinners
4. Can be a sign of a vaginal infection
5. Trauma due to sex
6. Local factors like polyps formed new due to elevated estradiol levels
7. Implantation sign especially when around day 10

So don't panic. Reach your doctor to get appropriate management solutions.

Know About Delayed Puberty

Dr.Arun Kumar Singh 92% (453ratings)
MD - General Medicine, DM - Endocrinology, MBBS
Endocrinologist, Delhi
Know About Delayed Puberty

Puberty results from activation of gonads (testes in boys/ ovaries in girls) by pituitary hormones LH and FSH. Activated gonads produce sexual hormones (testosterone in boys and estrogen in girls ) which are responsible for gender specific physical changes at puberty along with behaviour changes. Testosterone in boys is responsible for hair growth over pubic area and face with maturation of genital organs, breaking of voice, development of muscular and skeletal system. Similarly, estrogen in girls is responsible for breast development, maturation of genital organs with feminisation of body. Bone maturation with rapid height gain is seen at puberty both in boys and girls. Various systemic and hormonal disorders can result in either late or early puberty. 

LATE PUBERTY - 

Most of the boys show signs of puberty latest by age of 14 years and most girls start showing signs of puberty latest by age of 13 years. The earliest sign of puberty in boys is enlargement of testes and in girls is height spurt/breast development. When boys older than 14 years and girls older than 13 years don't have any signs of puberty it is called delayed puberty. 

CAUSES OF DELAYED PUBERTY - 

  1. Constitutional delay is most common cause of delayed puberty. The constitutional delay means child is not having any illness and he is going to develop puberty spontaneously at later age. But diagnosis of this condition can be made only after physical examination and investigations so that other causes of delayed puberty are ruled out. 
  2. Functional hypogonadotropic Hypopogonadism - Delayed but spontaneous puberty develops. This condition can be seen in systemic illnesses like chronic infections, poor nutritional status etc. 
  3. Hypogonadotropic Hypogonadism - Disorders of pituitary gland result in low LH and FSH so that testes/ovaries are not stimulated and sex hormone is not produced. This can be caused by various genetic disorders, brain tumours, head injury, brain radiation etc. 
  4. Hypergonadotropic Hypogonadism - In this scenario, LH and FSH levels are normal but gonadal are not able to produce sex hormones resulting in delayed puberty. 

CONSEQUENCES OF DELAYED PUBERTY - 
The absence of age specific pubertal changes cause anxiety and distress in children and their parents. These children may develop low self-esteem and are teased by their peers. Along with the poor development of physical signs of puberty, fertility is also affected in hypogonadism. And most importantly, delayed puberty can be the symptom of serious underlying illness like intracranial tumours etc. These children deserve medical attention to get best results. 

INVESTIGATIONS - 
Serum testosterone/estradiol with LH and FSH is done to find out where is defect i.e. whether at the level of pituitary gland or at the level of testes/ovaries. Further investigations depend on levels LH, FSH, estradiol/testosterone. Other useful investigations include prolactin, T4, TSH, ray hand for bone age, ultrasound pelvis, MRI pituitary gland etc. 

TREATMENT - 
After diagnosis is established, Testosterone/estrogen replacement should be started to boys older than 14 year and girls older than 13 years respectively. Hormone replacement is very effective and usually safe. In adulthood those with hypogonadotropic hypogonadism can be treated with LH and FSH to produce sperms/ eggs so that they can achieve fertility. If you wish to discuss about any specific problem, you can ask a free question.

2953 people found this helpful

Stress - How To Overcome It?

Dr.Priti Khatu 88% (40ratings)
MSc in Applied Psychology, MSc Health Psychology, PGCTC, PGC (Family Therapy)
Psychologist, Mumbai
Stress - How To Overcome It?

An idle mind is a devil’s workshop. When there is too much time on your hands with nothing to do, you end up thinking about things which are not going well, leading to depression. Come to think of it, if there is nothing that you can do to improve it, there is no point in wasting time over it. On the other hand, if there is something to improve the situation, just go ahead and do it, so everybody involved is happy. However, if there are too many other factors which are beyond control, then you need to see how to change your outlook towards it.

One such effective way is to keep yourself busy and distract yourself from it. The following are some simple measures, which can be very effective in dealing with stress.

  1. Sleep it off: One of the main reasons for depression is the physical exhaustion and lack of good rest. So, it is good once in a while to just sleep it off and give your body the much-deserved rest. This gives the brain a chance to begin to heal and feel better.
  2. Clean up the house: The home or the space you enter into indirectly indicates your state of mind. A clean home and workspace mean that much less clutter in the brain. Clean out the closet, give away your old stuff, and in the process, you would end up feeling good about having helped somebody. You will also realize how much excess stuff you have collected over the years. Stacked up in the attic and cartons, these were meant for use on “some fine day”, which never seemed to arrive.
  3. Exercise: Force yourself to exercise. While initially, it would be an ordeal, gradually you will enjoy it. Exercise also releases chemicals in the brain, which make you feel good about yourself. In addition, the physical benefits will start to show up, leaving you feeling elated and in a chirpier mood.
  4. Travel: When you go solo traveling, the amount of time you spend with yourself just increases. The changed surroundings will help you understand yourself better and come to terms with things that can be under your control. You learn to let go of things and come to terms with life. If time and money are limitations, go out and explore places in your own surrounding city or town. You will realize how little you know the city or town you live in.
  5. Hobbies: Whether it is learning to play the guitar or speak Spanish, pick something that you have always wanted to do over the years and work at it. You will see the depression vanish in no time.
3601 people found this helpful

Masturbation & Sex - Can Former Affect Latter?

Dr.A. K Jain 89% (6533ratings)
Bachelor of Ayurveda, Medicine & Surgery (BAMS)
Sexologist, Lucknow
Masturbation & Sex - Can Former Affect Latter?

A study by the Journal of Sexual Medicine revealed that men with more than ordinary masturbation habits may develop sexual problems. These habits are defined by techniques that cannot be replicated by the partner’s hand, mouth or vagina. These men were advised by sex therapists to maintain sexual abstinence and, then, to replace old preferences and practices with new ones. This had a positive effect on their sexual performance. The men reported greater satisfaction during sex with their partners and a decrease in sexual dysfunction.

Excess ejaculation can have the same hindering effect on sexual performance. When a man is addicted to erection and ejaculation in a particular way, his time with his partner can be affected negatively because of performance pressure that she may find herself facing. In such cases, refraining from masturbation is advised to be an easy solution.

Generally, excessive masturbation may also reduce the desire to have sex. In this situation, as well, refrain and control to have been so far identified as a way to improve performance and satisfaction. If that doesn’t help, however, it is likely that emotional issues such as anger, anxiety or stress are the causes.

Yet!!

There is no clearly-proven, direct effect that masturbation seems to have on sexual performance. It may be preferable, though, to save one’s desires for interaction with one’s partner as that increases drive and passion. But, this is also dependent on an individual’s libido. If masturbation leads to no loss of physical interest in the partner, then there is no supposed limit for solo rides!

4920 people found this helpful

Masturbation - How It Is Affecting Your Love Life?

Dr.M A Khokar 87% (65ratings)
MBBS
Sexologist, Bangalore
Masturbation - How It Is Affecting Your Love Life?

Any scientific progress has positive and negative impacts on the human society, and the digital revolution is not an exception. Information has never been made so quick and easy, and information related to sexual life is also available easily on the internet. Young adults are getting exposed to such material regularly. Such material makes them fall into bad or misinformed habits, and one such is masturbation.

Does masturbation offer benefits? Are there any side effects? Read on to get clarity.

Masturbation or self-pleasure might not be considered altogether bad. Several sex therapists argue that masturbation, when done with the right technique and when not done in excess, increases sexual stamina and libido. Not common in women as it is in men, masturbation is known to reduce stress levels in the person.

During orgasm, your body releases oxytocin in high quantities. The chemical oxytocin is known to decrease stress levels in both men and women. Hence, regular masturbation decreases stress in a person and considerably increases the sexual stamina as well. Also, this stress-buster reduces the risk of heart diseases as well.

Possible side effects that occur due to excessive masturbation

Be it through sex with your partner or through masturbation, orgasm offers a host of health benefits. However, when you indulge in it excessively, you may experience certain side effects, a few of which are described below.

  • Feeling guilty:A not-so-serious side effect is the association of guilt to the act. Most men who regularly masturbate can relate to this feeling. You may feel dirty and shameful, as your conscience thinks that the habit is immoral. However, you need not feel so, because, masturbation is neither immoral nor wrong.
  • Getting addicted to the habit:The next side effect is an addiction, and again, this too is not a serious side effect. The release of the stress-relieving chemicals and the possibility of experimenting your body can make you get addicted to the habit. Also, if you are single, there are high chances of you getting addicted to masturbation.

Notable symptoms are skipping your daily routine chores, missing social events, missing work, and reduced social interaction. When you notice one or more of these symptoms, you must either consciously regulate the habit or can seek the help of a sex therapist. Even if you are extremely addicted to the habit, a few sessions with your sex therapist will help you have a control on the habit.

How can it affect your sex life?

When you use the wrong technique while masturbating, there is a risk of your sex life getting affected. This is quite a serious side effect that needs to be addressed at the earliest. If your grip on the penis while masturbating is too tight, this may decrease sensation in sex life with your partner. You may try changing the technique of masturbation. If that doesn’t seem to work, it is necessary to seek expert help. When your participation in sex life is decreased, it is not only affecting you but also your partner. Decreased satisfaction in sex life, in turn, triggers a series of problems that will affect the relationship.

So, masturbation, when done moderately with the right technique, is beneficial. Else, things go haywire!

5673 people found this helpful

Does Masturbation Improve Performance In Bed?

Sexual Health Clinic
Sexologist, Delhi
Does Masturbation Improve Performance In Bed?

A study by the Journal of Sexual Medicine revealed that men with more than ordinary masturbation habits may develop sexual problems. These habits are defined by techniques that cannot be replicated by the partner’s hand, mouth, or vagina. These men were advised by sex therapists to maintain sexual abstinence and, then, to replace old preferences and practices with new ones. Masturbation had a positive effect on their sexual performance. The men reported greater satisfaction during sex with their partners and a decrease in sexual dysfunction.

Masturbating Can Improve Your Sex Life

Excess ejaculation can have the same hindering effect on sexual performance. When a man is addicted to erection and ejaculation in a particular way, his time with his partner can be affected negatively because of performance pressure that she may find herself facing. In such cases, refraining from masturbation is advised to be an easy solution.

Generally, excessive masturbation may also reduce the desire to have sex. In this situation, as well, refrain and control to have been so far identified as a way to improve performance and satisfaction. If that doesn’t help, however, it is likely that emotional issues such as anger, anxiety, or stress are the causes.

There is no clearly-proven, direct effect that masturbation seems to have on sexual performance. It may be preferable, though, to save one’s desires for interaction with one’s partner as that increases drive and passion. But, this is also dependent on an individual’s libido. If masturbation leads to no loss of physical interest in the partner, then there is no supposed limit for solo rides! In case you have a concern or query you can always consult an expert & get answers to your questions!


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In case you have a concern or query regarding sexual health ask a doctor online, you can consult the best sexologist doctor online, & get the answers to your questions.

 

5374 people found this helpful

Ovarian Function, Age, and Fertility!

Dr.Seema Jain 89% (60ratings)
MBBS, MD - Obstetrtics & Gynaecology, DNB (Obstetrics and Gynecology), Royal College of Obstetricians and Gynaecologists (MRCOG)
IVF Specialist, Pune
Ovarian Function, Age, and Fertility!

The ovaries are an important part of the female reproductive system. In a normal scenario, a woman has two ovaries that lie on either side of the uterus. Their main function is to produce eggs and release them into the fallopian tubes. These eggs then travel to the uterus where they may be fertilized. The ovaries are also responsible for the release of estrogen and progesterone. These hormones help regulate the menstrual cycle.

The functioning of the ovaries is directly related to a woman’s age. When a girl is born her ovaries have approximately 2 million eggs. These are in the form of follicles. By the time she reaches puberty, this number would have reduced to around 400,000. It is believed that a woman releases only around 450 eggs during her entire reproductive period. This is less than 1% of the eggs she was born with. During each menstrual cycle, one of the follicles will mature into an egg and be released. At the same time, some follicles may die. Thus, as a woman ages, the number of eggs available reduces. By her 30th birthday, the rate at which eggs are lost increases. By her 40th birthday, a woman’s eggs will die rapidly. Without a healthy egg being released sperm cells will have nothing to fertilize. Thus, ovarian functioning decreases as a woman grows older. This implies that the risk of infertility also increases as a woman grows older.

Along with a decrease in the number of eggs available the quality of eggs also reduces with age. Thus, though the ovaries may release an egg even when a woman is in her 40s, the chance of these eggs being fertilized is very low. Even if the egg is fertilized, women who conceive a child after the age of 40 have a high risk of miscarriage. There is no direct way to assess the quality of a woman’s eggs but some tests may help indicate the chances of getting pregnant. This includes a Basal FSH to indicate the level of follicle stimulating hormones, tests to determine the amount of Estradiol and tests to determine ovarian reserve. Ultrasounds can also help assess the number of follicles in the ovaries. This test is known as an Antral Follicle Count.

Infertility caused by decreased functioning of the ovaries is usually termed as unexplained infertility. In such cases, IVF is often the most preferred form of treatment.

In case you have a concern or query you can always consult an expert & get answers to your questions!

5140 people found this helpful