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Sanezil 5 MG Tablet

Manufacturer: Sigmund Promedica
Medicine composition: Donepezil
Prescription vs.OTC: Prescription by Doctor required

Sanezil 5 MG Tablet, a cholinesterase inhibitor, is used to treat a brain disorder that affects the ability to remember, communicate, think clearly, and perform daily activities and may cause changes in mood and personality in people who have Alzheimer's disease. It improves mental function by increasing the amount of certain chemicals in the brain. However, it does not cure Alzheimer’s disease completely. Possible side effects of this medicine include loss of appetite, difficulty sleeping, gastrointestinal upset, vomiting, diarrhoea or muscle cramping.

Certain conditions may require you to be extra careful while taking this medicine. Inform your doctor if you have these conditions :

  • Pregnant, planning to become pregnant, or are breast-feeding
  • Are taking any other prescribed or over the counter medicines.
  • Are allergic to medicines, foods, or other substances.
  • A history of certain heart problems, stomach or bowel problems, liver or kidney problems, lung or breathing problems, muscle problems, low thyroid hormone levels, or urinary blockage.
  • Brain lesions or tumours, a recent head injury, or a history of seizures
  • Have Parkinson disease or metabolism problems

Sanezil 5 MG Tablet comes as a tablet and an orally disintegrating tablet to take by mouth. It is usually taken once a day with or without food, in the evening just before bedtime. Your doctor may prescribe to you a low dose initially to decrease the risk of side effects and gradually increase your dose after 4 to 6 weeks. Your doctor may increase your dose again 3 or more months later. Use this medication regularly in order to get the most benefit from it.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Neurologist before using this medicine.

Sanezil 5 MG Tablet is used in the treatment of Alzheimer's disease which is a progressive brain disorder characterized by memory loss and difficulty in thinking.
Not recommended in patients with known allergy to Sanezil 5 MG Tablet.
In addition to its intended effect, Sanezil 5 MG Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Diarrhea Moderate Common
Loss of appetite Moderate Common
Nausea and Vomiting Moderate Common
Trouble sleeping Moderate Common
Muscle cramps Moderate Common
Dizziness Moderate Less Common
Frequent urination Moderate Less Common
Headache Moderate Less Common
Weight loss Moderate Less Common
Unusual bleeding Moderate Less Common
Join pain Moderate Less Common
How long is the duration of effect?
The effect of this medicine lasts for an average duration of 7 to 8 days.
What is the onset of action?
The time taken to reach peak concentration is 3 to 4 hours.
Are there any pregnancy warnings?
This medicine is not recommended for pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
Is it habit forming?
No habit forming tendency has been reported
Are there any breast-feeding warnings?
It is not known whether this medicine is excreted in breast milk. It is not recommended in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
Below is the list of medicines, which have the same composition, strength and form as Sanezil 5 MG Tablet , and hence can be used as its substitute.
Intas Pharmaceuticals Ltd
Glenmark Pharmaceuticals Ltd
Alkem Laboratories Ltd
Ranbaxy Laboratories Ltd
Missed Dose instructions
Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Overdose instructions
Seek emergency medical treatment or contact the doctor in case of an overdose.
United States
Sanezil 5 MG Tablet is cholinesterase inhibitors. It works by increasing the cholinergic function by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Disease
Bradycardia Major
This medicine is not recommended in patients with existing heart disease. An alternate medicine should be considered based on the clinical condition.
Lung disease Major
This medicine is not recommended in patients with lung disorders like asthma or COPD. Inform the doctor if you have any symptoms of breathing difficulty. An alternate medicine should be considered based on the clinical condition
Interaction with Alcohol
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Lab Test
Information not available.
Interaction with Food
Information not available.
Interaction with Medicine
Carvedilol Moderate
These medicines may lower the heart rate and blood pressure if taken together. Inform the doctor if you are receiving antihypertensives like carvedilol, metoprolol, and nifedipine. Any symptoms of dizziness, irregular heartbeat should be informed to the doctor. Dose adjustment or an alternate medicine should be considered based on the clinical condition.
Oxcarbazepine Moderate
Inform the doctor if you are receiving oxcarbazepine, carbamazepine as these medicines will decrease the effect of Sanezil 5 MG Tablet. Any symptoms of worsening of the condition should be reported to the doctor. Dose adjustments are to be made based on the clinical condition.
Tramadol Major
These medicines may increase the risk of seizures if taken together. The risk is more in the elderly population with the history of head injury or seizures. Any symptoms of seizures should be informed to the doctor. The dose of either of the medicines should be adjusted based on the clinical condition.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

This is for My father of Age 75 ,weight 43 kg and height 177 cm. He is under treatment for dementia related issues as described below. We are consulting with Neurologist and he was taking the tablet Donep of 10 mg for the last one year. Now he added one more medicine since there is no improvement and stills showing more angry and aggressive behavior. The medicine name is QUETIAPINE 25 mg. One tablet night after food When am browsing in internet it is not approved to older people with dementia related issues. It may cause serious issues. Is that correct? Or shall we continue with the medicine? New prescriptions cilacar 10 morning one Telma h 40 morning one Donamem 10 night one quetiapine 25 night one Atorfit cv 10 night one 1) He is having serious memory issue 2) He is not getting words while talking 3) He is able to read, write, Identify all the friends but always angry with everyone most of the time 4) some day he is very silent and normal 5) Most of the time he is getting he want to go from home, no answer where he want go, but someday he used to go to some of his friends home. Some days to temples. May be frequently 6) Some days he will bath/ brush two or three times. If we are reminding this he will get angry and will try to go out of home As per Neurologist it is because of one silent brain attack and dementia He is a retired Mathematics teacher, and this symptoms started some 4 year back. Now some days he is very violent because of the above reason Waiting for your feedback.

Psychiatrist, Bangalore
Der Dileep, Sorry to hear your father, Maths teacher, has dementia. The behavioral problems are not tolerated by the family members. If you start attending the family members' group, you will understand why your father gets angry and leaves home. If the family understands his present level of memory and accepts it as such, behaviour of your father will change. If you people point out accusingly or treat him as though he does it purposely, it will worsen. Donepezil is helpful in reducing behavioural problems. None of the antipsychotics are approved in dementia because it can cause falls and medical problems become worse. You have to decide which is worse and use Quetiapine whenever necessary.

My 83 years old mother has been diagnosed of Alzheimer's disease and with the first dose of allopathic medicine - DONEP- she ended up being admitted in the hospital in emergency for extreme weakness and nausea. Now she refuses to take that medicine. About a month back I started giving her homeopathic - BARYTA CARB 200 thrice a day 5 balls but do not see any improvement in her. I have heard that Ayurveda has good treatment for alzheimer, request you to please advise. When the memory test was done by the psychiatrist, my mother scored 20/30. She has no other health problems.

Psychiatrist, Bangalore
My 83 years old mother has been diagnosed of Alzheimer's disease and with the first dose of allopathic medicine - DON...
Your mother was diagnosed as Alzheimer's. Since her score is 20/30 (probably on MMSE), it must be mild dementia. It is unfortunate that she is unable to tolerate Donep (Donepezil). i hope it is a 5 mg tablet to start with. Since she does not have any other health problem, her life expectancy must be - many more years. Alzheimer's is a progressive disorder. Slowly she will become more and more forgetful and may have behavioural problems too. Donepezil will arrest the disorder from progressing further, though it may not improve her memory which she already lost. It will help if your mother has any behavioural problems also. If you think of all these benefits, you may try Donep with an anti vomiting drug. However please keep your mother's preserved memory active and encourage her in few memory games.
1 person found this helpful

I recently read that researchers believe certain foods might cure Alzheimer’s disease. Is this true? If so, which foods do this and how much would you have to consume to get the benefits?

Psychiatrist, Bangalore
I recently read that researchers believe certain foods might cure Alzheimer’s disease. Is this true? If so, which foo...
Dear lybrate-user, for curing alzheimer's so far nothing has come clinically. Of course we would like to research all the possible ones. Research findings to become clinically relevant needs more time and more replication of findings in different population. For preventing probably all healthy food habit may be helpful. May not be alzheimer's alone, generally any dementia, especially vascular ones.

My father suffering from parkinson from last 8 years. Now he is very week. 80%. Memory loss. Please reply. Suggest me some good medicine.

Psychiatrist, Nagpur
He might be having dementia as well with parkinson disease, tab donepezil might help, consult a psychiatrist nearby for help
1 person found this helpful

Table of Content

About Sanezil 5 MG Tablet
When is Sanezil 5 MG Tablet prescribed?
What are the contraindications of Sanezil 5 MG Tablet ?
What are the side effects of Sanezil 5 MG Tablet ?
Key highlights of Sanezil 5 MG Tablet
What are the substitutes for Sanezil 5 MG Tablet ?
What are the dosage instructions?
Where is the Sanezil 5 MG Tablet approved?
How does medicine works?
What are the interactions for Sanezil 5 MG Tablet ?