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Last Updated: January 27, 2022

Niacinamide is a vitamin B supplement. It is used for preventing low levels of niacin in the body. Insufficient Niacinamide in the body is known as pellagra. Deficiency of niacin in the body can lead to many serious conditions and diseases like dementia, swelling of tongue, peeling red skin, diarrhea etc.

The vitamin supplement is consumed orally, though Niacinamide salt is also present in creams for treating acne. anti-ageing products, hair shampoos and colouring treatments for hair. Niacinamide present in these products helps fight against conditions like wrinkles, psoriasis, dark spots, hyper-pigmentation, fine lines etc. It also helps prevent dry skin and improves circulation.

Niacinamide is considered safe and has minimal side effects. Some side effects include nausea, vomiting, diarrhea etc. Seek medical attention in case you notice any unusual effects such as excessive bleeding, persistent vomiting, any issue with the kidney or dark stool etc.

Consult your doctor before using Niacinamide in case you are pregnant or are planning to become pregnant, are breastfeeding, you are taking any other prescribed or non-prescribed drugs, have any allergies or are suffering from glaucoma, diabetes, low blood pressure or liver disease.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Dietitian/Nutritionist before using this medicine.

The medication is primarily used for the following conditions:

  • Nutritional Deficiencies

Here are some of the possible side effects of this drug:

  • Nausea

  • Portal Vein Fibrosis

  • Blockade Of Portal Blood Vessels

  • Dry Hair

  • Headache

  • Heartburn

  • Hepatobiliary Disorder

  • Liver Toxicity

  • Sore Throat

  • Stiffness Of Face

  • Disorientation

  • Fatigue

  • Is It safe with alcohol?

    Interaction with alcohol is unknown. Please consult your doctor.
  • Are there any pregnancy warnings?

    Niacinamide may be unsafe to use during pregnancy.
    Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
  • Are there any breast-feeding warnings?

    Unknown. Human and animal studies are not available. Please consult your doctor.
  • Is it safe to drive while on this medicine?

    Caution is advised when driving or operating machinery.
  • Does this affect kidney function?

    Caution must be taken in patients with kidney disease. Adjustment of dose is needed. Please consult doctor before consuming the drug.
  • Does this affect liver function?

    Caution must be taken in patients with liver disease. Avoid large pharmacological amounts in patients with a history of liver disease. Monitor liver function tests with high doses. Please consult doctor before consuming the drug.
  • Are there any missed dose instructions?

    If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
  • Are there any overdose instructions?

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Below is the list of medicines, which contains Niacinamide as ingredient

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Used by the body as a source of niacin; is a component of two coenzymes which is necessary for tissue respiration, lipid metabolism, and glycogenolysis; inhibits the synthesis of very low density lipoproteins; does not have hypolipidemia or vasodilating effects.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Lab Test

    False elevations of urinary catecholamines in some fluorometric determinations.
  • Interaction with Medicine

    • Oral hypoglycemics: Effect may be decreased by niacin.
    • Sulfinpyrazone and probenecid; niacin may inhibit uricosuric effects.
    • Aspirin decreases adverse effect of flushing.
    • Lovastatin (and possibly other HMG CoA reductase inhibitors): Increased risk of toxicity (myopathy).
    • Adrenergic blocking agents additive vasodilating effect and postural hypotension.
  • Interaction with Disease

    Use caution in heavy ethanol users, unstable angina or CAD (risk of arrhythmias at high doses), diabetes (interfere with glucose control), renal disease, hepatic disease, active gallbladder disease (can exacerbate), gout, or allergies.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MBBS, Master in Healthcare Administration, Diploma in Occupational Health
General Physician
Table of Content
About Niacinamide
What are the uses of Niacinamide
What are the contraindications of Niacinamide ?
What are the side effects of Niacinamide ?
Key highlights of Niacinamide
What are the dosage instructions?
Medicines containing Niacinamide
How does this medication work?
What are the interactions of Niacinamide ?