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Metrogyl 400 MG Tablet

Manufacturer: Jb Chemicals
Medicine composition: Metronidazole
Prescription vs.OTC: Prescription by Doctor not required
Last Updated: September 21, 2019

Developed by JB Chemicals, Metrogyl comprises of Metronidazole which is antibacterial and antifungal. It is used in the treatment of bacterial as well as fungal infection. Its course of action is entering into an organism and forming a free radical.

The alteration in the molecule which promotes influx of the molecule creates a concentration gradient which will ultimately interfere with the DNA synthesis of the molecule and inhibit the growth of the organism.

Metrogyl is used as a sole medicine or in a combination with other medicines for the treatment of inflammatory diseases, dracunculiasis, giardiasis, endocarditis, amebiasis, and trichomoniasis.

It is used only for certain bacterial and parasitic infections of the respiratory tract, vagina, skin, and joints.

It is also used to ward off any infections that occur before or after the operations of the intestines and helps in decreasing the onset of infections contracted after surgical procedures in patients which are experiencing elective disorders of the anus, colon, and rectum.

Below are the conditions for which this medicine is used:

  • Amebiasis

  • Bacterial Vaginosis

Some of the side effects that may be observed in patients are:

  • How long is the duration of effect?

    The effect of Metrogyl which is used for treating bacterial infections last for an average of 24 hours after consumption.

  • What is the onset of action?

    Within 1-2 hours after consumption, the peak effects of the medicine are observed.

  • Are there any pregnancy warnings?

    Pregnant women should not use this medication before using this drug.
  • Is it habit forming?

    Metrogyl doesn’t have any habit forming tendencies.

  • Are there any breast-feeding warnings?

    Metrogyl must not be used by breastfeeding women until it has been deemed as absolutely necessary.

  • Is It safe with alcohol?

    Consult your doctor before consuming alcohol.
  • Is it safe to drive while on this medicine?

    Metrogyl can cause drowsiness in the patient, which can be very dangerous while driving. The patient must refrain from performing any activity that requires alertness in the patient.

  • Does this affect kidney function?

    For patients suffering from any kidney abnormalities, the consumption of Metrogyl can cause kidney disorders such as kidney failure. Consulting the doctor before consumption is a prudent idea.

  • Does this affect liver function?

    Patients that have a history of liver damage and Crohn’s disease can be severely affected as it may cause stomach and intestinal cancers.

Below is the list of medicines, which have the same composition, strength and form as Metrogyl 400 MG Tablet , and hence can be used as its substitute.

  • Are there any missed dose instructions?

    If you miss a dose of this drug, take the missed dose as soon as you remember. Do not double your dose to make up for the missed dose.
  • Are there any overdose instructions?

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Metronidazole belongs to the class anthelmintics. It enters into the organism and forms the free radical. A concentration gradient is created in the organism due to alteration in the molecule and promotes the influx of the molecule. Thus, the free radical and the altered molecule will interfere with the DNA synthesis and stops the growth of the organism.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Disease


    Metrogyl interacts strongly with disulfiram which is used for the treatment of alcoholism. If the two are taken in combination, the patient may suffer from mental problems. Busulfan is used in the treatment of cancer which can cause adverse effects due to high levels of accumulation in the body.

  • Interaction with Alcohol


    The interaction of Metrogyl with alcohol can cause the reaction of disulfiram in patients during nitroimidazole therapy. The inhibition of aldehyde dehydrogenase (ALDH) is caused. It is highly recommended to not consume alcohol while being treated with Metrogyl.

  • Interaction with Food


    Metrogyl is not known to have any reactions with food.

  • Interaction with Medicine


    Metrogyl reacts severely with medicines that contain Warfarin compounds. It has moderate reactions with Ethinyl Estradiol, Atorvastatin, and Disulfiram compounds.

Ques: What is Metrogyl 400 mg Tablet?

Ans: Metrogyl belongs to the antiprotozoal class of drugs. It helps in treating infections in the stomach, genital areas. It is not recommended to take alcohol with this medicine. Take this medicine only if it is necessary to reduce the development of resistance.

Ques: What is Metrogyl 400 mg Tablet used for?

Ans: Metrogyl is used to treat fungal and bacterial infections.

Ques: What are the side effects of Metrogyl 400 mg Tablet?

Ans: Metrogyl can cause a few side effects which include Agitation, Fever and chills, Skin rash, Vaginal irritation and Loss of appetite etc.

Ques: Can Metrogyl 400 mg Tablet be taken empty stomach?

Ans: Most of the patients are suggested to take this medicine along with food. Whereas it is not crucial to take it with food and in some cases, patients have taken it empty stomach.

Ques: Is metrogyl 400 mg tablet used for bacterial infections?

Ans: Yes, metrogyl is used for bacterial infections.

Ques: how long do i have to take metrogyl 400 mg tablet?

Ans: Usually, Metrogyl should be taken for 7 days. However, dosage of this medication depends on Patient to patient.

Ques: Can Metrogyl be taken empty stomach?

Ans: It is advised to take Metrogyl after consuming meals to have better digestion of medication.

Ques: Can the use of Metrogyl cause metallic taste?

Ans: Yes. Metrogyl 400 mg tablet can lead to metallic taste.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
General Physician
Table of Content
About Metrogyl 400 MG Tablet
What are the uses of Metrogyl 400 MG Tablet
What are the contraindications of Metrogyl 400 MG Tablet ?
What are the side effects of Metrogyl 400 MG Tablet ?
Key highlights of Metrogyl 400 MG Tablet
What are the substitutes for Metrogyl 400 MG Tablet ?
What are the dosage instructions?
How does this medication work?
What are the interactions of Metrogyl 400 MG Tablet ?
FAQs about Metrogyl 400 MG Tablet