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Overview

Imusporin 100Mg Oral Solution

Imusporin 100Mg Oral Solution

Manufacturer: Cipla Ltd
Medicine composition: Cyclosporine
Prescription vs.OTC: Prescription by Doctor required

Imusporin 100Mg Oral Solution is an immunosuppressant. This medication is used in the prevention of transplanted organ rejection from the body. This medication is used in combination with adrenal corticosteroids. Imusporin 100Mg Oral Solution can also be used in patients with already a history of chronic rejection.

On using this medication you may experience side effects such as diarrhoea, drowsiness, vomiting, stomach pain, headache, dizziness, skin rash, hives, difficulty in breathing, chest pain, swelling of facial parts, rapid or irregular heartbeat, pain during urination, seizures, ringing in the ears, mental/mood disorders, kidney/liver disorders and changes with vision. If the reactions persist or become worse over time contact your health care professional right away.

Don?t use this medication if; you are allergic to any ingredient contained within Imusporin 100Mg Oral Solution, you are receiving radiation or ultraviolet therapy. Before using this medication tell your doctor if; you are allergic to any food/medicine/substance, you are taking any medications, you have seizures/cancer/ high blood pressure/weak immune system, you have kidney/nerve/brain disorders, you are pregnant or are breastfeeding a baby.

The dosage for this medication should be prescribed by the doctor based on your condition. The usual dose in adults is 2-4 mg given via IV infusion once daily.

organ transplantation
, nephrotic syndrome, uveitis and
In addition to its intended effect, Imusporin 100Mg Oral Solution may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Headache
Increased hair growth
Increased blood pressure
Renal dysfunction
Loss of appetite
Tremor.
Is It safe with alcohol?
Interaction with alcohol is unknown. Please consult your doctor.
Are there any pregnancy warnings?
Iminoral 100mg capsule may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Are there any breast-feeding warnings?
Unknown. Human and animal studies are not available. Please consult your doctor.
Is it safe to drive while on this medicine?
There is no data available. Please consult doctor before consuming the drug.
Does this affect kidney function?
Caution should be used in patients with impaired renal function.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Below is the list of medicines, which have the same composition, strength and form as Imusporin 100Mg Oral Solution, and hence can be used as its substitute.
RPG Life Sciences Ltd
Are there any missed dose instructions?
If you miss a dose of Cyclosporine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Medicine
GENTICYN 80MG INJECTION
OLSERTAIN 40MG TABLET
Zathrin Redimix Suspension
Pratham 200Mg/5Ml Rediuse Suspension

Popular Questions & Answers

I am a women of age 31 years. And im suffering from aplastic anemia. Cam I suggest any solution?

MD, DM - Clinical Haematology
Hematologist, Ludhiana
I am a women of age 31 years. And im suffering from aplastic anemia. Cam I suggest any solution?
Hello lybrate-user Yes there are solutions for aplastic anaemia. The most appropriate one depending on your disease severity will be to consider exploring options for a bone marrow transplant. Other therapies include use of dugs like ATG and cyclosporine. This requires expertise. You will benefit from following up with a hematologist to initiate these. Best.

I did KFT two times. And results showing high creatinine both the times. Normal creatinine range 0.7-1.4 and I have 1.63. So tell me what should I do now.

MBBS
General Physician, Jalgaon
I did KFT two times. And results showing high creatinine both the times. Normal creatinine range 0.7-1.4 and I have 1...
Please Avoid oily spicy and fast food, non veg food, processed food, outside food, rice Take plenty of water daily Take salads and fruits more Take Gokharu kadha 20 ml twice a day for 3 months Punarnavasav 20 ml twice a day for 3 months Check sr creatinine and blood urea 4 wks Send me report on Lybrate.

I am suffering for eye dry ness from 4 years can you please help me to get rid of it. Can you please cure me.

MBBS, DOMS, MS - Ophthalmology, , Fellowship in phacoemusification
Ophthalmologist, Patna
I am suffering for eye dry ness from 4 years can you please help me to get rid of it. Can you please cure me.
Dryness is not a disease which you can cure by putting lubricating eye drops for few days, while working on smartphone , computer & watching TV for long time without giving importance to the health of eyes. Number of blinking drastically goes down from around 24 per minute to around 8 per minute while working on computer etc causing severe dryness, blurring of vision, headache & increased blinking to compensate dryness .One who works on smartphone etc will have to change &will have to learn how to work on computer for long time without giving any trouble to eyes .One should look away from computer after every 10 minute & should take rest for 10 minutes after every two hours .Every body knows that to become man from monkey took millions of years according to Darwin theory & how you expect that our eyes will adjust to computer in 20 yrs,nature takes its own time, computer development is just 20 yrs history, so you will have to take the help of lubricating eye drops to neutralise the effect of computer etc,you may use nano eye drops 4-5 times daily + gancigel at bed time + cap I Dew mega one cap once daily x 3 months.

My serum creatinine is 1.8.my diabetes is now fasting 100 and pp 170. Bp is now 150/90. I take telma am 1-0-1 and for diabetes maclazid 80 2-2-2.kindly suggest the measures to reduce serum creatinine.

MBBS
General Physician, Cuttack
My serum creatinine is 1.8.my diabetes is now fasting 100 and pp 170. Bp is now 150/90. I take telma am 1-0-1 and for...
A) Drink Herbal/green tea (2 glass daily), drink 6-8 glasses of water (not excess), b) Restrict salt intake, Reduce protein intake like meat/fish/chicken/egg, diary product (cheese/milk/yogurt/butter), white bread, white flour, sweet/tea/coffee/ beer/wine. C) Avoid strenuous physical activity/Exercise (Go for light exercise like Yoga, Walking instead of strenuous exercise like running/playing basket ball/foot ball), d) sleep well (7-8) hours daily e) Avoid nephro toxic drugs like Ibuprufen/Ace inhibitor, cyclosporine, f) Control Diabetes/Hypertension, g) Do thyroid function test to rule out hypothyroidism, h) Avoid potassium containing food like orange, banana, potato, brocoli, spinach, bean, peas dry fruits. I) Take low potassium containing fruits like apple, blue berry, corn, cucumber, J) Avoid excess salt/salty food, excess protein like Red meat/ Diary product. K) Avoid phosphorous rich food like cheese/fish/pumpkin/soybeans. L) Take cabbage, cauli flower, carrot cucumber, omega 3 rich food, raw onion, garlic, turnip, raddish, m) Consult physician for medicine if the creatine level is still high??
1 person found this helpful

Sir. Viral conjunctivitis ke Karan mujhe dhundhla dikhai padta hai. Mai tear drop ka use kr rha huuuu. Kya ye completly thik ho skta hai. Plzzz help with us.

Fellowship in Comprehensive Ophthalmology, DOMS
Ophthalmologist, Sangrur
Sir. Viral conjunctivitis ke Karan mujhe dhundhla dikhai padta hai. Mai tear drop ka use kr rha huuuu. Kya ye complet...
hello it is conjunctivitis Prevention a. maintain eye hygiene b. use two handkerchief (one for each eye) c. keep hands clean Treatment a. antibiotic eyedrop b. lubricating eyedrop c. antibiotic ointment at night kindly consult local opthalmologist and get yourself examined if there is corneal involvement then you may need cyclosporine eyedrop

Popular Health Tips

Excess Facial Hair? You May Have A Hormone Imbalance!

MBBS, MRCGP ( UK), Diploma in Diabetes (UK), DFSRH (UK), DRCOG (UK), CCT (UK)
Endocrinologist, Hyderabad
Excess Facial Hair? You May Have A Hormone Imbalance!

Majority of women like to look into the mirror and find not an extra strand of hair on her face, be it the upper lip or near the ears. While it is not uncommon for women to have hair on these and other areas, most women resort to multiple ways to get rid of this. The pattern of this unnecessary hair growth is very similar to the pattern seen in males normally.

This condition of excessive hair growth is known as hirsutism and can be caused by multiple causes, as listed below.

  1. Genetic or racial: While the European women have a more clean face that is free of hair, the Mediterranean and Indian women are highly likely to have more facial hair growth. There is also a strong family history relation, and it is hereditary.
  2. Androgens (testosterone): This is a male hormone, essential for the development of male sexual characters. Though it is present in very minute amounts in all women, in some, there could be higher than these minimal levels, leading to minor masculine characters, facial hair being one of them.
  3. Hormonal imbalances: There are multiple hormonal issues which can manifest as increased facial hair growth. The two most common ones include polycystic ovarian syndrome (PCOS) and adrenal conditions including tumours, Cushing's syndrome, and hyperplasia. In all these cases, there is increased amount of androgens, leading to excessive facial hair.
  4. Medication side effect: Some medications like testosterone, cyclosporine, anabolic steroids, and Minoxidil also lead to increased amounts of facial hair in women. Some other medications used to treat migraines, seizures, schizophrenia, and hypertension can also cause hirsutism. This is indirectly due to increased levels of male hormones in the system, producing these effects.
  5. Birth control pills: These also affect the hormone levels and lead to increased facial hair.
  6. Obesity: Most women with facial hair are also on the heavier side, and most people have a reduction in hair once weight is managed.

Treatment: The underlying cause should be treated for controlling hair growth. If there is an inducing medication, an alternative should be looked at. While hormone levels can be altered, in most cases, not much can be done. These need to be dealt with using one of the following methods - depilatory creams, waxing, plucking, shaving, laser reduction, electrolysis, and weight loss.

When reading through the above, it is obvious that a lot of causes for hirsutism point towards hormones. This helps to identify hormonal disorders in their earlier stages, which are managed with lesser complications. The next time you feel there is more hair on your chin or cheeks, get your hormone levels checked.

In case you have a concern or query you can always consult an expert & get answers to your questions!

3712 people found this helpful

All That You Wanted To Know About Liver Transplantation!

MBBS, DNB ( General Surgery)
Liver Transplant Surgeon, Pune
All That You Wanted To Know About Liver Transplantation!

The liver has many functions, including building proteins and other substances for the body to use, removal of waste products and toxins from the blood drug metabolism and energy storage. Liver disease causes these crucial functions to fail and when the failure is too severe to respond to medication liver transplantation may be an option.

Apollo Hospitals is among the few recognized transplantation centers in the country and has one of the largest transplantation registries. As liver transplantation is a major surgical procedure, the patients and family have quite a lot of concern areas. This broucher provides brief answer to frequently asked questions.

The information contain herein is of general nature and should not be construed as specific medical advice. Please consult your doctor for more details.

GLOSSARY

  1. Ascites: A build up of fluid in the abdomen.
  2. Autoimmune: A condition that results when the bile ducts inside and outside the liver don’t have normal openings. Bile becomes trapped in the liver causing jaundice and cirrhosis. If this condition is present from birth then without surgery it may cause death.
  3. Biopsy: Removing a small piece of tissue to view under a microscope.
  4. Cirrhosis: A chronic liver condition cause by scar tissue and damage to cells. Cirrhosis makes it hard for the liver to remove poisons (toxins) like alcohol and drugs from the blood. These toxins build up in the blood and may affect the brain.
  5. Cyclosporine: An immunosuppressant used after transplantation to prevent rejection.
  6. Immunosuppressant: Medicines that stop your immune system from attacking bacteria viruses and transplanted organs.
  7. Jaundice: A symptoms of many disorders. Jaundice causes the skin and white of eyes to turn yellow.
  8. Mycophenolate mofetill: An immunosuppressant used after transplantation to prevent rejection.
  9. Sirolimus: An immunosuppressant used after transplantation to prevent rejection.
  10. Steroids: A group of immunosuppressant used after transplantation to prevent rejection.
  11. Tacrolimus: An immunosuppressant used after transplantation to prevent rejection.

What are the donor organ options that are used for transplantation in children?

  • Reduced size liver graft: a piece of a liver is taken from a beain-dead person(cadaver donor)
  • Living donor transplant: A piece of a liver from adult living donor and is used as a transplant for a child. Over the past 10 year, nearly 1000 of these transplants have been done throughout the world. They have been just as successful as transplants of whole organs. There are some risks of adult donation for transplant to a child. These risks seem to be much smaller than the risks of a living donor transplant to an adult.

Are there technical problems in doing a transplant on a child?

Yes. It is a little more difficult because the blood vessels are very small. Also, the care after surgery must be done in ICUs that can handle such small children.

Do children get the same ani-rejection drugs as adults?

In general, children get the same type of drugs that adults get. However, children may have different side effects. Therefore, only doctors who specialize in this field should handle the follow-up of children after transplants.

What makes a transplant successful?

First, you must have good medical care. Then, families and patients should make every effort to keep in touch with their medical terms. Children who get liver transplants will need to take drugs on schedule, see their doctor often and may need more procedures. All this will help to make transplants successful and will help to give long and healthy lives to the children. So make sure you stay in touch with your transplant team and follow their advice. Ask for counseling when you have any problems.

What does my liver do?

  • It helps digest your food
  • It clears some wastes from your blood
  • It makes proteins that help your blood to clot
  • It helps control the way your body, uses food and works with the body’s defense system
  • It helps use and store vitamins
  • It breaks down many drugs

What are the signs of liver problems?

Some signs of liver problems are:

  • Feeling weak and sick in your stomach and losing appetite
  • Muscle wasting(becoming skin and bones)
  • Fluid build-up in the abdomen(ascites)
  • Yellow skin and eyes(Jaundice)
  • Forgetfulness, confusion or coma(encephalopathy)
  • Swollen hands/ legs
  • Itching
  • Bruising, bleeding easily and nose bleeds
  • Blood in vomitus, bloody/ black bowel movements

What is liver transplantation?

Liver transplantation is surgery to remove a diseased liver and replace it with a healthy one. This kind of surgery has been done for four decades. Across the world thousands of people have had liver transplants and now lead normal lives.

Being tired and losing your appetite can be signs of liver problems. Liver transplants can help adults and children.

PEDIATRIC LIVER TRANSPLANTAION

Liver transplantation is now one of the best treatments for fatal liver diseases in children. New drugs and ways of doing surgery have greatly improved patient survival rates. In the liver transplants for children, there are two main issues.

  1. What caused the liver failure in the first place?
  2. What is the severity of disease process and how soon does the child need a liver transplant.

Why do children need liver transplant?

  • Billiary artesia: This is a disease in which a child is born with no bile ducts. It is the most common reason for liver transplants in children
  • Problems in digesting and using food: ‘Inborn errors of metabolism’ including the following conditions:
  • Alpha-I-antitrypsin deficiency tyrosinemia and wilson’s disease.
  • Lipid storage(Gaucher’s disease, Niemann-pick disease, Wolman’s disease, cholesterol ester storage disease)
  • Carbohydrate storage diseases(galactoserria and glycogen storage diseases)
  • Liver Cancers: Some liver cancers are found only in children
  • Sudden liver failure: This is a sudden liver failure that can cause death. It can have many causes. Mostly it comes from too much paracetamol or other drugs. In this kind of liver failure, a liver transplant can cure the problem if done early.

What is involved in the donor-evaluation process?

Donors undergo a thorough check-up that includes:

  1. Blood tests: Determine donor’s blood type, to see that it matches that of the person in need of the transplant. Blood tests are done to test the donor’s liver, kidney, and thyroid. Other trests are done to check for viruses such as hepatitis and HIV(the virus that causes AIDS)
  2. Physical Examination: If donor and recipient blood types are a close match the donor will get physical examination.
  3. Ultrasound: An ultrasound is done for the liver, other organs and the blood vessels
  4. Other Tests: Such as MRI, and CT Scans, help to give a complete view of the donor’s organs
  5. Tests of the lungs and heart may also be done. It takes 2 to 4 days for a donor to go through these tests. In an emergency situation, it can be done in as little as 48 hours

For how long does the donor remain hospitalized?

Donors stay in the hospital for up to 7 days after surgery. They may spend their first night after surgery in the ICU. The nest day they often go to the general surgical floor where the nurses have experience in caring for liver donors. Donors are encouraged to get out of bed and walk as soon as they are able.

How long before the liver donor is fully recovered?

For the most part, it takes about 4 weeks to recover from surgery. In the month after leaving hospital donors return to the hospital regularly to be checked. Donors often get back to work within 3 to 6 weeks. The medical staff will let you know when it is safe to return to normal life.

What are the donor’s health care costs?

The health insurance of the person who gets the transplant covers the donor’s health care costs. This includes the costs of the check up, doctor’s fess, hospital costs, and follow-up visits after surgery.

What are the reasons for needing a liver transplant?

In adults, the most common reason for liver transplantation is Liver cirrhosis. Cirrhosis is caused by many different types of liver injuries that destroy healthy liver cells and replace them with scar tissue. Cirrhosis can be caused by viruses such as hepatitis B and C, alcohol, autoimmune liver disease, build-up of fat in the liver and hereditary liver diseases. Sometimes the cause of liver cirrhosis is not known.

In children, the most common reason for liver transplantation is a billiary atresia. Bile ducts, which are tubes that carry bile out of the liver, are missing or damaged in this disease and obstructed bile causes cirrhosis. Bile helps digest food.

Other reason for needing liver transplantation is certain liver cancers, benign liver tumors, and hereditary diseases.

Sudden or rapidly developing liver failure may sometimes affect children and adults. The common causes of certain viral illness and reaction to some medicines like excess does of pain killers and even certain herbal/ traditional medicines. A liver transplant can save a life if undertaken at the right time.

How will I know whether I need a liver transplant?

Based on your sickness and liver disease status, your doctor may recommend you to the liver transplant unit for further evaluation. You will meet the liver transplant team. The team is usually led by a liver transplant surgeon and includes liver specialists (hepatologists), nurses, and other health care professionals. The transplant team will arrange blood tests, x rays, and other tests to help make the decision about whether you need a transplant and whether a transplant can be carried out safely.

Other aspects of your health like the condition of your heart, lungs, kidneys, immune system, and mental health will also be checked to be sure you’re strong enough for surgery.

Can anyone with liver problems get transplant?

You cannot have transplant if you have

  • Cancer in another part of your body
  • Serious heart, lung or nerve disease
  • Active alcohol or illegal drug abuse
  • An active severe infection
  • Inability to follow your doctor’s instructions

How did living-donor liver transplantation begin and how common is it?

Living donor transplants were first done in children because of the long waiting period for cadaver organs and increasing death rate on the list. It was done in children in the 1980s and is now being done in adults for the last 8 years. In India because of relative lack of cadaveric organs, the majority of transplants are done using living donor organs.

Who can become a donor?

People who want to be liver donor are carefully checked to ensure that they can safely give a part of their liver and that their liver is healthy. The first concern is the safety of the donor as well as being sure that the graft will work for the person in need. The risks to the donor are real. Discuss this with your doctor. In general liver donors must:

  • Be good in health
  • Have a blood type that is a close match to the blood of the person in nedd.
  • Not have a selfish motive for donating

There should be no pressure of any kind on a person to donate part of his liver nor should there be any money given or received.

LIVING DONOR TRANSPLANTATION

What is a living donor liver transplant?

A living-donor transplant is when someone who is alive gives a part of his or her liver to a person who needs a transplant. Family members such as parents, sisters, brothers, adult children or someone close, such as a spouse, may offer to give part of his or her healthy liver. This can be done because a healthy liver can grow new tissues. After the transplant, the liver parts of both the donor and person in need will grow and form complete organs.

What are the benefits of living donor liver transplantation?

The best reason for living donor transplant is that it shortens the waiting time for a liver. The timing of the surgery can be planned. The chance for as successful transplant is increased. Today, thousands of patients await liver transplantation but only handful cadaveric organs become available every year. A living-donor transplant gives those in need an early transplant before their liver failure gets worse and their livers are in danger.

How long does it take to get a new liver?

If the transplant team recommends that you need a transplant, you will be counseled regarding your options of living donor liver transplant or cadaver liver transplant.

If you have a living donor in your family your waiting time could be as short as one week. The living donors and donated livers are tested before transplant surgery. The testing makes sure the liver is healthy, matches your blood type and is the right size so that it has the best chance of working in your body.

In case you do not have a living donor, your name will be placed on a waiting list with your consent. Your blood type, body size and how sick you are, plays a role in deciding your place on the list. Currently, the sickest people are at the top of the list, so you may have to wait your turn.

While you wait for a new liver you and your doctor should talk about what you can do to stron for the surgery. You will also start learning about taking care of a new liver.

Where do the livers for transplantation come from?

Whole livers come from people who are brain dead (heart beat still present). These people are on breathing machines in various hospital ICUs. This type of donor is called “cadaveric donor”. Alternatively, a healthy person in the family can donate a part of his or her liver for the patient with liver failure. This kind of donor is called a ‘living donor’. More information on living donor liver transplantation is included in the latter part of this booklet.

Financial resources/ Health Insurance

You should check to be sure that you will be able to cover the cost of liver transplantation and prescription medicines. You will need certain medicines after the surgery and some for the rest of your life. Check with your employer, health insurance policy or aid organizations if they can support you in part or full.

What happens in the hospital?

When a liver is available, you will be prepared for the surgery. If your new liver is from a living donor, both of you and the donor will be in surgery at the same time. If your new liver is from a person who has recently died, your surgery will start when the new liver arrives at the hospital.

Can I go back to my daily activities?

Yes. After a successful liver transplant, most people can go back to their normal daily activities. Getting your strength back will take some time, depending on how sick you were before the transplant.

You will need to check with your doctor on how long your recovery period will be

  • After recovery, most people are able to go back to work
  • Most people can go back to eating as they eat before. Some medicines may cause you to gain weight others may cause diabetes or rise in your cholesterol. Meal planning and a balance low fat diet can help you remain healthy.
  • Most people can engage in physical activity after a successful liver transplant
  • Most people returned to normal sex life after liver transplantation. It is important for a woman to avoid becoming pregnant in the first year after transplantation.

You should talk to your transplant team about sex and reproduction after transplantation.

If you have any questions, you may check with your doctor before starting any activity.

Eating a healthy diet and taking the medications are part of taking care of your new liver.

What are the other problems that can damage the liver transplant?

Return of the problem that made the transplant necessary in the first place in less than 10% of patients with liver transplants. Also hepatitis C virus may damage a transplant if the patient was infected before the operation took place.

Rarely occurring problems include:

  • Blockage of the blood vessels going into or out of the liver
  • Damage to the tubes that carry bile in to the intestine

What if the transplant doesn’t work?

About 90% transplanted livers are still working after 1 year and about 85% livers are working at 5 years after transplant. If the new liver does not work or if your body rejects it, your doctor and the transplant team will decide whether another transplant is necessary.

How do I take care of my liver after I leave the hospital?

After you leave the transplant center at the hospital, you will see your doctor often to be sure your new liver is working well. You will have regular blood tests to check that your new liver is not being damaged by rejection, infections or problems with blood vessels and bile ducts. You will need to avoid sick people and report any illness to your doctor. You will need to eat a healthy diet, exercise and not drink alcohol. You should only use medicines, including ones you can buy without a prescription, after counseling your doctor. It is important to do what your doctor says to take care of your new liver.

During Surgery

The surgery can take from 6 to 14 hours. While the surgeon removes your diseased liver, other doctors will prepare the new liver.

The surgeon will disconnect your diseased liver from your bile ducts and blood vessels before removing it. The blood that flows into your liver will be blocked or sent through a machine to return to the rest of your body. The surgeon will put the healthy liver in place and reconnect it to your bile ducts and blood vessels. Your blood will then flow into your new liver.

After Surgery

You will stay in the hospital for an average 2 to 3 weeks to be sure your new liver is working. You will take medicines to prevent rejection of your new liver and to prevent infections. Your doctor will check for bleeding, infections and rejection. During this time you will start to learn how to take care of yourself and use your medicines to protect your new liver after you go home.

In the hospital, you will start eating again. You will start with clear liquids, then switch to solid food as your new liver starts to work.

What are the likely complications following a liver transplant?

Minor wound infection and discharge of liquefied fat is seen in about 10% of people. This will settle with little or no intervention. Major wound infection needing another surgery is extremely rare.

By now you are aware that liver transplantation involves making a lot of connections. There is an extremely small chance that these connections can become too tight or too loose. We have a very highly trained team of doctors who are able to treat them with minimally invasive techniques without resorting to another surgery.

Hepatic Artery Thrombosis (HAT) / Clotting of the hepatic artery is a rare complication seen in less than 4% of the patients and portal vein thrombosis is even rarer and is seen in less than 1% of the patients. When identified, the clot will have to be removed and it will involve another surgery. In spite of all this, if we are not successful, re-transplantation will be necessary.

What is rejection?

Rejection occurs when your body’s natural defenses, called the immune system, damage the new liver. Your immune system keeps you healthy by fighting against things that don’t belong in your body, such as bacteria and viruses. After a transplant, it is common for your immune system to fight against the liver and try to destroy it.

How is rejection prevented?

To keep your body from rejecting the new liver, you will have to take medicines. These drugs such as tacrolimus, cyclosporine, steroids, sirolimus and mycophenolate mofetil are called immunosuppressant. Immunosuppressants weaken your immune system’s ability to reject your new liver.

Do immunosuppressants have any side effects?

Yes. You can get infections more easily because these drugs weaken your immune system. You will need to stay away from people who are sick. These drugs may also increase your blood pressure, cause your cholesterol to rise, cause diabetes, weaken your bones and may damage your kidneys in the long run. Steroid drugs may also cause changes in how you look by causing weight gain. Your doctor and the transplant team will monitor these effects and treat you for any complications that may occur.

What are the signs of rejection?

Doctors will check your blood for liver enzymes at the first sign of rejection. Often rejection does not make you feel ill. Sometimes rejections can cause- pain, fever, jaundice, and changes in liver function tests.

Often a liver biopsy is needed to diagnose rejection. For a biopsy, the doctor takes a small piece of the liver to examine under a microscope. Blood tests will show if the new liver is being rejected.

Why liver is an important organ of the body?

The liver is one of the largest organs in your body. It helps digest the food you eat and convert it into energy. It also helps fight infections and cleans your blood, thus making it a very vital organ.

How lifestyle can affect the health of liver?

Due to our changing life style patterns, alcohol is consumed either as a status symbol or to cope up with stress. Alcohol puts a lot of stress on the liver, such continuous state of stress usually results in liver damage.

What are the different common diseases related to liver?

Cirrhosis, Viral hepatitis (Most common form across the world are Hepatitis A, B & C), fatty liver disease and alcoholic liver disorders are the common disease of liver.

What is a liver transplant and why is it done?

Simply put ‘Liver Transplantation’ is surgery to remove a diseased or injured liver and replace it with a healthy one from another person, also called as a donor.In adults, the most common reason for needing a liver transplant is ‘Cirrhosis’. This is caused by various different types of diseases which destroy the healthy liver cells and replace them with scar tissues.

What are the types of liver transplants?

There are two types of liver transplants – Living Donor and Deceased Donor Transplants. In case of the 'living donor' Liver Transplant, a portion of Liver from the living donor is removed and transplanted in the recipient patient. In both recipient and donor, the liver regenerates to necessary size in about 6 to 8 weeks. Only near relatives can donate. In deceased donor liver transplants, the donor is a brain dead person.

How much time is needed for patient to recover after liver transplant?

Recovery time ranges from 1 to 2 weeks. Proper care, follow-up and life-long medications are required for the new Liver to function properly.

Can liver grow back to normal after the transplant?

Yes. Liver is the only organ which can regenerate in case of living donor liver transplant, a portion of liver from the living donor is removed and transplanted in recipient patient. In both recipient and donor, liver regenerates to necessary size in 6-8 weeks. Only near relatives can donate liver in this case.

What does Sahyadri Hospital has in offering for Liver care?

Sahyadri Hospitals has an A-Z Liver Wellness Clinic dedicated for management of all types of diseases related to Liver, Pancreas, Bile ducts & Gall bladder. It Offers state-of-the-art facilities for Liver, Kidney & Pancreas Transplant with 24/7 availability of dedicated multi-disciplinary ‘Liver Team’, including Hepatologist, Critical Care Physicians and Liver Transplant Surgeons, a well-equipped Intensive care unit with dedicated nurses, physiotherapist and nutritionist.

What are the major risks in donating?

As with any major surgery, there will be pain from the incision, which will get better with time. Other risks to the donor include bleeding, infection, and temporary bile leaks. Fatalities in transplantation have been reported from certain transplant centers in the world but it is rare. Most have full recoveries and are healthy. Discuss regarding risk to the donors with your transplant surgeon.

What happens during donor surgery?

The incision is the shape of mirror image of ‘L’. The gallbladder is always removed. The donor’s liver is split into two parts. One part is removed for the transplantation. The surgeon then closes the wound with sutures and staples. There are later removed at a follow-up visit to the surgeon’s office. The liver begins to heal and grow new tissue. It takes about 8-21 weeks for the liver to grow back to its normal size.

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Natural Treatment For Gout

M.Sc. in Dietetics and Food Service Management , Post Graduate Diploma In Computer Application, P.G.Diploma in Clinical Nutrition & Dietetics , B.Sc.Clinical Nutrition & Dietetics
Dietitian/Nutritionist, Mumbai
Natural Treatment For Gout

1. Try essential oils for relief

Essential oils for relief:-

There are many ways to use an essential oil. The simplest way to use an essential oil for the treatment of gout is with a carrier oil.

  • Select the oil of your choice and a bottle of carrier oil (olive oil and coconut oil are both oils that you may have in your kitchen that is good carrier oils).
  • In a small bowl, mix a tablespoon of the carrier oil and 4-6 drops of the essential oil. Blend well.
  • Apply topically to affected joint and massage into skin.
  • Repeat 2-3 times per day.

2. Supplements and other natural treatment for gout:-

There are a variety of supplements that can be taken that have reported benefits for the natural treatment of gout.

  • Vitamin c may reduce uric acid. Some experts recommend taking sodium ascorbate as it is less acidic than ascorbic acid; the typical recommended dosage is 500-1000mg twice daily, but you should discuss this with your physician.
  • Apple cider vinegar reportedly makes the body more alkaline. Apple cider vinegar for gout may help with gout symptoms. The recommended daily dose is 1-2 tablespoons in 8 ounces of water. This can be sipped throughout the day.
  • Baking soda is another reported natural treatment for gout and is supposedly a pain reliever. To try this treatment, mix ½ teaspoon of baking soda in 8 ounces of water and drink in one sitting. This can be repeated several times throughout the day, with the maximum daily dosage being four teaspoons of baking soda in one day, and should be decreased as pain improves.
  • Bromelain is a compound that is found in pineapple; it can also be purchased as a supplement. It is thought to be a highly effective compound in treating gout and may even have anti-cancer benefits.
  • Castor oil can be used topically to relieve pain. Soak an old cloth with castor oil and apply to the affected joint. Wrap the fabric and joint with plastic wrap and an ace bandage. If you do not have any issues with neuropathy, apply heat to the joint as well. Leave on overnight.
  • Epsom salts baths can be relaxing and also relieve pain. Place 1-2 cups of epsom salts in a warm bath and soak for 20 minutes. You can also use a footbath if you desire just to soak your feet; place 1/3 cup of epsom salts in the footbath with warm water.  

3. Using food as a natural treatment for gout:-

Changing your diet is one of the ways you can treat gout effectively. There are some types of foods which offer an anti-inflammatory defense and others which lower uric acid levels.

1. Coffee – whether it is regular or decaf – appears to lower uric acid levels.

2. Cherries – both cherries and cherry extract – reduce uric acid levels in the blood, as well as decrease the number of gout flare-ups.

3. Blueberries and blackberries – these berries are loaded with a type of antioxidant which helps to protect the arterial walls damaged by gout. You can reduce inflammation by adding blackberries and blueberries into your diet.

4. Folic acid – this b vitamin is commonly given with b6 or b12 to reduce homocysteine levels, an amino acid that causes high uric acid levels.

5. Herbs – si miao san is a remedy that contains four different herbs to treat gout and support kidney function. Other herbs which may include birch leaf, juniper berry.

 Importance of prenatal nutrition

Important nutrition tips for gout:-

Some foods containing purines are fine to eat as long as you are thoroughly hydrated. In addition to hydration, there are other dietary and lifestyle factors to monitor in order to stay pain free.

  • Lay off soda – sugary drinks like non-diet sodas are some of the most common perpetrators for gout pain. Fructose, the highly concentrated sugar in soda, has been attributed as the cause of gout inflammation. Quit drinking soda altogether or switch to diet soda. Patients with gout had no incidences of diet soda causing gout pain.
  • Avoid crash dieting – trying to lose weight quick (crash dieting) causes not only your blood sugar levels to rise and fall drastically, but your uric acid levels as well. People who crash diet are often dehydrated as a result, which has been proven to exacerbate gout pain.

Gout pain relief options:-

1. Drink lots of water – several studies have linked a high water intake to lower incidences of gout pain. The amount of water each individual should drink daily depends on their current medical conditions.

2. Eat low fat dairy products – in recent studies, individuals who consumed a serving or more of low fat milk each day were observed to have less uric acid in their blood. Low fat dairy has been shown to help the body excrete uric acid due to its high protein and low purine content.

3. Avoid certain medications – cyclosporine is a drug that is used to treat chronic eye infections by increasing tear production. Unfortunately, one of its side effects is the production of excess uric acid in the blood, leading to gout.

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Psoriasis - Types, Symptoms, and Treatment

Dermatologist,Cosmetologist,Venerologist &Sexologist
Dermatologist, Visakhapatnam
Psoriasis - Types, Symptoms, and Treatment

Psoriasis is a common autoimmune disorder of the skin that results in the formation of thickened and elevated plaques of cells that remain covered by scales (loose, whitish-silver scales). In psoriasis, the skin cells multiply at an alarming rate resulting in the scaling of the skin. Though non-contagious, psoriasis can be itchy and often painful. Psoriasis mainly affects the scalp, elbow, and knees. In some, the condition may also affect the palms, feet (soles of the feet), and the torso.

As per a survey, psoriasis is known to affect approximately 2.2% of the total adult population. Psoriasis can also affect children (children under the age group of 5-8 years are mostly affected by this inflammatory skin disorder).

Psoriasis Can of Different Types

  1. Plaque Psoriasis: As the name suggests, this type of psoriasis results in the formation of plaques of cells (thickened and elevated) on the skin surface. One of the most common types of psoriasis, plaque psoriasis affects the scalp, knees, and elbow.
  2. Pustular Psoriasis: Pustular psoriasis mainly affects the hands and the feet of the adults whereby white blisters (pus-filled) appear on the affected area of the skin. The skin also appears red and inflamed.
  3. Guttate Psoriasis: This type of psoriasis usually affects the legs, torso, and arms. Common in children (sometimes young adults), Guttate psoriasis results in the formation of small red spots.
  4. Inverse Psoriasis: In Inverse psoriasis, shiny red (bright red) inflammations or lesions appear on the armpits, groyne, breasts.
  5. Erythrodermic Psoriasis: Though rare, this type of psoriasis is marked by extreme redness of the skin. There is also shedding of the scales (in the form of sheets). The skin more or less appears sun burnt.

Symptoms:
The symptoms associated with psoriasis include

  1. Elevated and inflamed red patches covered by whitish- silver scales (plaques).
  2. The nails appear thick and pitted.
  3. There is a pain in the joints followed by swelling.
  4. At times, the affected skin may crack resulting in bleeding.
  5. Soreness, itching and a burning sensation around the red patches.

In psoriasis of the scalp,

  • There may be the formation of scales (usually mild).
  • In severe cases, there may be crusting (the full scalp) which can spread to the forehead, ears (inside and behind), in the beard or even around the nose.

Treatment:
Though there is no definite treatment for psoriasis of the body and the scalp, the following medications may prove to be helpful

  • Medications like Methotrexate and Cyclosporine (immunosuppressant drugs), Retinoids, and Biologics (injected intravenously) may provide some relief.
  • Patients may also benefit from light therapy, anthralin, topical corticosteroids as well as vitamin D analogs.

Precaution and care
For psoriasis of the scalp

  • Before the treatment, it is important to remove (and soften) the scales. Medicated shampoos that contain salicylic acid can be used to remove the scales.
  • Use of petroleum jelly or medicated oils and ointments (as recommended by the doctor) can be helpful.
  • For better results, you can keep the scalp covered (preferably with a shower cap) after applying the ointment.

For Psoriasis of the Body

  • Avoid the skin from getting dry. You can use a medicated lotion or a moisturizer.
  • Drinking and smoking can worsen the situation. Avoid these vices as much as you can.
  • Avoid using hot water while bathing. To keep your skin moisturised, you can add oil or salt to the water (bathwater).

In case you have a concern or query you can always consult an expert & get answers to your questions!

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Excess Facial Hair In Women - Causes And Treatment

MBBS, MD - Dermatology
Dermatologist, Faridabad
Excess Facial Hair In Women - Causes And Treatment

Excess facial hair growth in a woman results from a condition known as the hirsutism. The growth in hair pattern is exactly similar to that of an adult male. Areas, where abnormal hair growth is visible, are chest, above the lips, etc. These hairs are dark, but fine in nature. They are more commonly known as peach fuzz.

There could be a number of reasons for excess facial hair in a woman:

  1. Genetic reasons: Women from the Indian sub-continent or Mediterranean region are more likely to have facial hair as compared to their American, European and East-Asian counterparts. One of the common reasons for facial hair growth is genetics. It is a trend that runs in the family, it is more likely that a woman will get it. There is not much that can be done in this case except managing the hair growth effectively.
  2. Imbalance of the hormone: Abnormal hormone production can lead to hirsutism. In many cases, there are conditions where female starts producing male hormones leading to abnormal hair growth in the face. One of the most common causes of facial hair growth is polycystic ovarian syndrome (PCOS). This again is a hormonal imbalance leading to facial hair growth. Even adrenal gland related disorders such as cushing's syndrome, Adrenal cancer and congenital adrenal hyperplasia can lead to excess hair.
  3. Medications: Certain medication can lead to excess hair growth in the face. For instance, the certain steroid such as anabolic can lead to excess hair growth. Minoxidil is also known to cause hirsutism if taken in excess of 1 ml per day. Other medication related to testosterone and cyclosporine can lead to excess facial hair in females. It is advised to follow the doctor’s advice before consuming any of these medicines.
  4. Androgens: Although androgen is a male hormone, it is present in minute quantities in women too. Facial hair increase is nothing, but the sudden increased production of androgen in a female. Even birth control pills can lead to an increased production of androgen in the body. In these cases, it is very important to seek medical advice.

Treatment and remedies:
Medical help:
One should get medical help at the earliest if one of these conditions matches their symptoms:

  • The hair growth is sudden and abrupt.
  • One witness male features such as increases muscle, acne and reduced breast size.
  • Certain medication has led to the hair growth.

Home Remedies:

  • Usage of shaving, plucking and depilatory cream
  • Laser hair reduction procedure shows immediate results in stopping and countering any further hair growth.
  • Electrolysis can be tried to permanently damage the follicles.
  • Weight loss is another good solution to excess hair growth. If you wish to discuss about any specific problem, you can consult a dermatologist.
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