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Overview

Esperal 250mg Tablet

Manufacturer :  Torrent Pharmaceuticals Ltd
Medicine Composition :  Disulfiram
Prescription vs OTC : Prescription by Doctor required

About Esperal 250mg Tablet

Esperal 250mg Tablet is an alcohol-abuse deterrent. It’s used to treat alcoholism along with counseling therapies. It prevents the unpleasant side effects that come with alcohol consumption by blocking the breakdown of alcohol.

On using this medication you may experience side effects such as headache, bad taste in mouth, drowsiness, darkening of urine, seizures, weakness, fatigue, reduced appetite, mental or mood problems, swelling and skin rash. If you face any of allergic reactions or any adverse reaction contact your health care provider right away.

Before using this medication notify your doctor if: you are allergic to any of the ingredients contained within Esperal 250mg Tablet, you are alcoholic, you have severe heart problems/ brain damage/ lung diseases, you have any other allergies, you have diabetes/ seizures/ underactive thyroid/ depression, you are taking any prescription or non-prescription drugs, you are pregnant or are planning to become pregnant or are nursing a baby.

The dosage should be prescribed by the doctor based on your overall medical history and current condition. The usual dose in adults for treating alcohol dependence is 500 mg, taken orally once daily for 1-2 weeks. The maintained dose is 250 mg taken once daily.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    What are the uses of Esperal 250mg Tablet

    • Alcoholism

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    What are the side effects of Esperal 250mg Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    Key highlights of Esperal 250mg Tablet

    • Is It safe with alcohol?

      Alconol 500mg tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).

    • Are there any pregnancy warnings?

      Alconol 500mg tablet may be unsafe to use during pregnancy.
      Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

    • Are there any breast-feeding warnings?

      Unknown. Human and animal studies are not available. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      Caution is advised when driving or operating machinery.

    • Does this affect kidney function?

      There is no data available. Please consult doctor before consuming the drug.

    • Does this affect liver function?

      There is no data available. Please consult doctor before consuming the drug.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    What are the substitutes for Esperal 250mg Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Esperal 250mg Tablet , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of Disulfiram, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    How does this medication work?

    This medication acts as an alcohol-abuse inhibitor. It interferes with the way your body metabolizes alcohol. The alcohol is metabolized by aldehyde dehydrogenase enzyme and get break down into acetaldehyde compounds. It also hinders the proper functioning of the enzyme. As a result, acetaldehyde is not converted to acetic acid and gets accumulated in the bloodstream instead.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

      What are the interactions of Esperal 250mg Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

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        Epsolin 50Mg/2Ml Injection

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        Mezolam 7.5Mg Injection

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        Medzol 1Mg Injection

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      References

      • Disulfiram-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/disulfiram

      • Disulfiram-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 7 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00822

      • DISULFIRAM tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=DISULFIRAM

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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