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Sufital 250Mg Tablet

Manufacturer: Talent Healthcare
Medicine composition: Disulfiram
Prescription vs.OTC: Prescription by Doctor required

Sufital 250Mg Tablet is an alcohol-abuse deterrent. It’s used to treat alcoholism along with counseling therapies. It prevents the unpleasant side effects that come with alcohol consumption by blocking the breakdown of alcohol.

On using this medication you may experience side effects such as headache, bad taste in mouth, drowsiness, darkening of urine, seizures, weakness, fatigue, reduced appetite, mental or mood problems, swelling and skin rash. If you face any of allergic reactions or any adverse reaction contact your health care provider right away.

Before using this medication notify your doctor if: you are allergic to any of the ingredients contained within Sufital 250Mg Tablet, you are alcoholic, you have severe heart problems/ brain damage/ lung diseases, you have any other allergies, you have diabetes/ seizures/ underactive thyroid/ depression, you are taking any prescription or non-prescription drugs, you are pregnant or are planning to become pregnant or are nursing a baby.

The dosage should be prescribed by the doctor based on your overall medical history and current condition. The usual dose in adults for treating alcohol dependence is 500 mg, taken orally once daily for 1-2 weeks. The maintained dose is 250 mg taken once daily.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Psychiatrist before using this medicine.


In addition to its intended effect, Sufital 250Mg Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.



Metallic taste


Gastrointestinal disturbance


Is It safe with alcohol?

Alconol 500mg tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).

Are there any pregnancy warnings?

Alconol 500mg tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Are there any breast-feeding warnings?

Unknown. Human and animal studies are not available. Please consult your doctor.

Is it safe to drive while on this medicine?

Caution is advised when driving or operating machinery.

Does this affect kidney function?

There is no data available. Please consult doctor before consuming the drug.

Does this affect liver function?

There is no data available. Please consult doctor before consuming the drug.

Are there any missed dose instructions?

If you miss a dose of Disulfiram, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Sufital 250Mg Tablet acts as an alcohol-abuse inhibitor. It interferes with the way your body metabolizes alcohol. The body breaks down alcohol into acetaldehyde compounds, which are further broken down by aldehyde dehydrogenase enzyme. Sufital 250Mg Tablet prevents the enzyme from functioning properly. As a result, acetaldehyde is not converted to acetic acid, and gets accumulated in the bloodstream instead.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

Interaction with Medicine

Epsolin 50Mg/2Ml Injection

Mezolam 7.5Mg Injection

Medzol 1Mg Injection

What are you using Sufital 250Mg Tablet for?
How much was the improvement?
How long did it take before seeing improvement?
More than 2 days
Within 2 hours
Within 6 hours
Within 2 days
Within a day
How frequently did you take this medicine?
Once a day
Not taking on daily level
Four times A Day
Thrice a day
How did you take this medicine?
With or without food
With Food
Empty stomach
What were the side effects of this medicine?
Gastrointestinal disturbance
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

Sometimes I get the side effect of disulfiram tab. Such as vomiting, tiredness etc. What should I do after this?

MD - General Medicine
General Physician, Delhi
Sometimes I get the side effect of disulfiram tab. Such as vomiting, tiredness etc. What should I do after this?
If you are having disulfiram and drinking after that, you will suffer from vomiting and tiredness. If you aren't drinking, you might need some other medications for the symptoms.

Dear sir/mam. I am using disulfiram 250 for alcohol treatment. Can I use prodep 20 with disulfiram to reduce anxiety and depression?

MD - Psychiatry
Psychiatrist, Chennai
Dear sir/mam.
I am using disulfiram 250 for alcohol treatment.
Can I use prodep 20 with disulfiram to reduce anxiety ...
There are no interactions between the two, you can use them. But consult a psychiatrist before taking prodep as the antidepressants are tailored to the symptoms. All the best.
2 people found this helpful

I am suffering from gastritis since long days. I am alcoholic. Taking disulfiram but I am drinking alcohol too.

MS - General Surgery, MBBS
General Surgeon, Delhi
I am suffering from gastritis since long days. I am alcoholic. Taking disulfiram but I am drinking alcohol too.
Avoid outside spicy and fried food. Walk about 3-5 kms daily. There should be gap of 2hrs after dinner and sleep. Small and frequent meals is of help. Keep your blood sugar controlled. Raise your bed about 4" from headend side. Get your gastroendoscopy done. Tab nexpro-l 1 tab empty stomach.

I am using disulfiram 500 tablet for deaddiction from alcohol as prescribed by psychiatrist is it helpful & safe.

MD - Psychiatry
Psychiatrist, Chennai
I am using disulfiram 500 tablet for deaddiction from alcohol as prescribed by psychiatrist is it helpful & safe.
It s helpful, it s an anti deterrent agent. Avoid exposure to anything and everything which has alcohol, u can develop severe reaction

It's for my husband 46 years. He has Addiction of alcohol. Any medicine for de addiction. disulfiram will good for him?

Psychiatrist, Bangalore
It's for my husband 46 years. He has Addiction of alcohol. Any medicine for de addiction. disulfiram will good for him?
Dear lybrate-user, Many psychiatrists are trained in addiction medicines. It is better that you consult one of them. First 1-2 weeks, focus will be on assessment or body health, motivational level, admission to hospital and treatment of withdrawal symptoms. Then for next 9-12 months, he will be given anti-craving medicines and focus will be on prevention of lapses and relapses. For Disulfiram, you need to take him into confidence and take his consent. Alcohol disulfiram interaction can be severe that needs instant treatment. It causes aversion to alcohol and he will be scared to drink alcohol. This needs to be done under the continued guidance by psychiatrist. It will be good for him if his motivational level is high.
4 people found this helpful

Popular Health Tips

Ways On How To Fight Back Addiction!

MD - General Medicine
Sexologist, Delhi
Ways On How To Fight Back Addiction!

Addiction is a brain ailment that is characterized by irrational engagement in satisfying stimuli despite of argumentative circumstances. Addiction is an ailment where the brain's Reward system malfunctions and only responds to persistently greater level of addictive stimulus like morphine, cocaine, etc.

There are many varieties of addiction like alcoholism, gambling, sexual intercourse, etc. These force a person to isolate himself from the entire society and indulge in his or her addictions. If they are not supplied with the drugs they may react violently and may even die.

Drug treatment is a type of treatment which is intended to aid the abused users stop the uncontrollable usage of drugs and protect them from the adverse effects of it. This treatment has a variety of forms and takes a lot of time as the drug abuse is a chronic disorder and cannot be treated in a short term. Below mentioned are some of the ways by which you can fight back addiction effectively.

• For individuals who are addicted to drugs such as opium and nicotine (Tobacco) are treated with drugs such as methadone, naltrexone for opium addicted individuals and with varenicline and bupropion for tobacco addicted people.

• For individuals who are greatly addicted to alcohol Disulfiram and acamprosate are the best medications that are available.

• Many individuals are addicted to the prescribed drugs and their treatment is the same as that of drug abuse that affects the brain. Like the medicine buprenorphine, can be used to treat both heroin obsession and addiction to medications for opium pain treatment.

Behavioral treatments may help people to take part in drug abuse therapies and teach ways to cope up with drugs and help them to against relapse if it occurs.

• Group therapies are the latest form of treatment that is advised to the addicted individuals. Group therapies provide the individual social support and help in enforcing behavioral incidents that will help the lead a non-drug-using lifestyle.

• Lastly individuals who are greatly addicted to alcohol or drug abuse or any kind of addictions suffer from depression and also face social, legal and family problems.


5 people found this helpful

Ways to Deal With Alcoholism

MBBS, MD - Psychiatry
Sexologist, Surat
Ways to Deal With Alcoholism

Alcoholism is a severe problem, which can make a person's life miserable and also make the society detest him. The aim of treatment for alcoholism is abstinence or staying away from alcohol use. The treatment of alcoholism can only begin when an alcoholic accepts the problem and realizes that he must get rid of the habit for his own good and the good of his loved ones.

There are three main stages in the treatment of alcoholism:

  1. Detoxification: Detoxification is the first step required after a person stops using alcohol. The detox phase may include seizures, hallucinations and delirium tremens. The patient must be kept under proper observation.
  2. Rehabilitation: This step includes proper counseling and medications to provide the person with skills and motivation to remain sober. This can be done by making him an inpatient or outpatient, depending on the condition of the patient.
  3. Maintaining sobriety: This is the most important step where a person's self-will is tested. He needs to stay away from alcohol after getting out of rehabilitation for which he requires support. Meetings conducted by the Alcoholic Anonymous should be attended regularly by a recovering alcoholic.

For people in the early stage of alcoholism, discontinuing alcohol may cause several withdrawal symptoms such as poor sleep and anxiety. For long term alcoholics, severe withdrawal symptoms are experienced, which include shaking of the body, spasms, hallucinations and panic.

Several medicines may be required in the recovery period of an alcoholic.
Anti-anxiety medicines such as benzodiazepines are used for treating withdrawal symptoms like poor sleep. The medicines are usually used in the detoxification period. After this phase, they are discontinued.
For maintaining sobriety and to abstain from alcohol, several medicines are given to recovering alcoholics. A drug known as disulfiram is used after the completion of the detox period. This medicine reacts with alcohol metabolism and causes a person to vomit, become confused, have blurry vision and experience difficulties in breathing after consuming alcohol.

A medicine called naltrexone may be used for reducing alcohol craving. It can be prescribed even when a person drinks. It is given in the form of an injection. Antidepressants are also given to patients to reduce anxiety and depression.

Other ways to deal with alcoholism:
Several other instructions must be strictly followed by a recovering alcoholic to avoid relapse. They are as follows:

  1. People and places related to drinking should be avoided, and a person should make new nonalcoholic friends.
  2. Support groups and AA meeting must be attended regularly for motivation.
  3. Dependence on alcohol should be eliminated by starting different activities and getting involved in things.

Alcoholism is a severe problem, which may lead to death in case of extremities. Alcoholism can ruin a person's life, and proper measures must be taken to eliminate alcoholism.

13 people found this helpful
Table of Content
About Sufital 250Mg Tablet
When is Sufital 250Mg Tablet prescribed?
What are the side effects of Sufital 250Mg Tablet ?
Key highlights of Sufital 250Mg Tablet
What are the dosage instructions?
How does medicine works?
What are the interactions for Sufital 250Mg Tablet ?