Contiflo D Combipack

Contiflo D Combipack, is an alpha blocker that helps to relax the enlarged muscles of an affected prostrate and bladder. It helps to ease out the symptoms of benign prostatic hyperplasia (BPH) which includes difficulty in urination, increased need to urinate at odd times, and a weak stream.

Being a medicine for men, Contiflo D Combipack is not for use for women and children. It is important that you brief the doctor about all other medication you’re currently on, as it may lead to adverse reactions with similar medicines such as prazosin, silodosin, etc. Side effects include a drop in blood pressure that may lead to dizziness or fainting.

Contiflo D Combipack is not to be taken if you are allergic to it. Let your doctor know if you have:

• Liver
• Kidney disease
• Low blood pressure
• History of prostrate cancer.

Contiflo D Combipack is taken orally, with the dosage depending on your medical condition and response to the treatment. It is important that you take the capsule at the same time every day, thirty minutes after your meal, daily. Taking it regularly would help to increase its effectiveness.

Primary use of this medicine are as follows:

• Benign Prostatic Hyperplasia

• Hypersensitivity

Common side effects of this medicine may cause include:

• Headache

• Dizziness

• Abnormal Ejaculation

• Rhinitis

• Chest Pain

• Weakness

• Insomnia

• Decreased Libido

• Diarrhoea

• Nausea

• Stomach Discomfort

• Bitter Taste

• Back Pain

• Pharyngitis

• Cough

• Sinusitis

• Infections

• Syncope

• Vertigo

• Is It safe with alcohol?

  Taking Contiflo D Combipack with alcohol may lower your blood pressure. This can cause dizziness or feeling like you might pass out, especially when getting up from a sitting or lying position.

• Are there any pregnancy warnings?

  Contiflo D Combipack is highly unsafe to use during pregnancy.
  Human and animal studies have shown significant adverse effects on the foetus. Please consult your doctor.

• Are there any breast-feeding warnings?

  Unknown. Human and animal studies are not available. Please consult your doctor.

• Is it safe to drive while on this medicine?

  It may cause dizziness. Exercise caution if you have to drive or operate a machinery.

• Does this affect kidney function?

  No dose adjustment is needed for patients with the mild to moderate renal disease. Not advisable in patients with the severe renal disease.

• Does this affect liver function?

  No dose adjustment is needed for patients with the mild to moderate liver disease. Not advisable in patients with the severe liver disease.

• Are there any missed dose instructions?

  The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of overdose.

This medication behaves as an antagonist to alpha-1A as well as alpha-1B-adrenoceptors within the prostatic urethra, bladder neck, prostate and prostatic capsule. Alpha1-adrenoceptors subtypes such as alpha-1A, alpha-1B and alpha-1D.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

• Interaction with Medicine

  • Alpha-adrenergic blockers should not be used in combination with other alpha-adrenergic blocking agents.
  • Warfarin: Use caution with concomitant administration of warfarin and Contiflo D Combipack.
  • Cimetidine resulted in a significant decrease (26%) in the clearance of Contiflo D Combipack which resulted in a moderate increase in Contiflo D Combipack AUC (44%); therefore, use with caution when used in combination with cimetidine (especially doses >0.4 mg).
  • No dosage adjustments necessary if administered with atenolol, enalapril, or Procardia XL®.

• Interaction with Disease

  Not intended for use as an antihypertensive drug. May cause orthostasis, syncope or dizziness. Patients should avoid situations where injury may occur as a result of syncope. Rule out prostatic carcinoma before beginning therapy with tamsulosin. Anticipate a similar effect if therapy is interrupted for a few days, if dosage is rapidly increased, or if another antihypertensive drug is introduced.