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Overview

Chloramphenicol 250 MG Capsule

Manufacturer: Torque Pharmaceuticals Pvt Ltd
Medicine composition: Furosemide
Prescription vs.OTC: Prescription by Doctor required

Chloramphenicol 250 MG Capsule is known to be a loop diuretic, also known as a water pill. The drug when taken reduces the amount of salt that the body absorbs. The excess salt is then excreted by the body through the urine. The drug is primarily used to control fluid retention in the body of patients suffering from liver disease, kidney problems and congestive heart failure. Thus, the drug helps in the creation of more urine which gets rid of excess fluid and salt produced in the body.

You can take this medicine orally with a meal or without. Try not to take the drug around your bedtime so as to prevent the urge to urinate throughout the night. The dosage prescribed, usually depends on your age, your health and your body’s response to the drug. In case of children the dosage is also determined according to their weight. You doctor will first start you off with a low dose to see how your body accepts the drug. If you do not develop any side effects he may increase the dosage.

Side effects are a common occurrence when you take any medication. While some side effects are quite common and disappear as your body adjusts to the drug, others are more severe and can create complications. Chloramphenicol 250 MG Capsule can cause some minor side effects like dizziness, problems with vision, headache and faint feeling. If you do experience dizziness, ensure that you move slowly to avoid any accidents.

Chloramphenicol 250 MG Capsule can result in severe dehydration as it creates the need to urinate frequently. Therefore, if you do experience symptoms like weakness, confusion, drowsiness, crams in the muscles, nausea or feel excessively thirst contact your doctor and seek medical helps immediately.

Very rarely do patients suffer from an allergic reaction to Chloramphenicol 250 MG Capsule. But if it does occur consult your doctor and get treatment done.

Chloramphenicol 250 MG Capsule is used in the treatment of hypertension which is a condition with an increase in the blood pressure caused by fluid overload due to genetic and environmental factors.
Congestive Heart Failure
Chloramphenicol 250 MG Capsule is used in the treatment of congestive heart failure characterized by the decrease in the blood flow to the body parts.
Edema
Chloramphenicol 250 MG Capsule is used to remove water that accumulated in the hands, feet, and ankles associated due to cirrhosis of the liver, and renal disease
Not recommended in patients with known allergy to Chloramphenicol 250 MG Capsule or other diuretics.
Anuria
This medicine is not recommended in patients with condition Anuria (a condition wherein the kidney is unable to produce urine).
In addition to its intended effect, Chloramphenicol 250 MG Capsule may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Low potassium and magnesium Major Common
Decreased calcium level Major Common
Hearing impairment Major Rare
Headache Major Rare
Weakness Minor Less Common
Increased sensitivity of the skin to sunlight Minor Less Common
Muscle spasm Minor Rare
Skin rash Minor Rare
Low potassium and magnesium Major Common
Decreased calcium level Major Common
Hearing impairment Major Rare
Headache Major Rare
Weakness Minor Less Common
Increased sensitivity of the skin to sunlight Minor Less Common
Muscle spasm Minor Rare
Skin rash Minor Rare
Duration of effect
The effect of this medicine lasts for an average duration of 6 to 8 hours after an oral dose and 2 hours after an intravenous dose.
Onset of action
The effect of this medicine can be observed in 30 to 60 minutes after an oral dose, 30 minutes after an intramuscular dose and 5 min after an intravenous dose.
Pregnancy warnings
This medicine is not recommended for pregnant women.
Is it habit forming?
No habit forming tendency has been reported.
Breast-feeding warnings
This medicine is not recommended for women who are breastfeeding.
Below is the list of medicines, which have the same composition, strength and form as Chloramphenicol 250 MG Capsule, and hence can be used as its substitute.
Missed Dose instructions
The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.
Overdose instructions
Seek emergency medical treatment or contact the doctor in case of overdose.
Missed Dose instructions
The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.
Overdose instructions
Seek emergency medical treatment or contact the doctor in case of overdose.
India
United States
Japan
India
United States
Japan
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Disease
Diabetes Moderate
Taking this medicine may increase the blood glucose levels. Close monitoring of blood glucose levels is necessary. Inform the doctor about your medical condition. Suitable dose adjustments should be made based on the clinical condition.
Interaction with Alcohol
Alcohol Moderate
Consumption of alcohol is not recommended while you are taking this medicine. It may increase the risk of dizziness and fainting. Avoid performing activities that need mental alertness like operating machinery or driving a vehicle.
Interaction with Lab Test
Lab
Information not available.
Interaction with Food
Food
Information not available.
Interaction with Medicine
Nonsteroidal anti-inflammatory drugs Moderate
Use of Chloramphenicol 250 MG Capsule with nonsteroidal anti-inflammatory drugs like diclofenac, aceclofenac may increase the risk of kidney injury. Drink adequate amount of water to prevent dehydration. Close monitoring of blood pressure and kidney function are necessary. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.
Aminoglycoside antibiotics Major
Chloramphenicol 250 MG Capsule is not recommended with aminoglycoside antibiotics like amikacin, gentamycin, streptomycin due to the increase in the risk of kidney injury and hearing problems. Inform the doctor if you experience any symptoms of hearing loss, dizziness, sudden weight gain. An alternate medicine should be considered based on the clinical condition.
Antidepressants Moderate
Escitalopram may lower the blood sodium levels if coadministered with diuretics like Chloramphenicol 250 MG Capsule. Inform the doctor if you may have symptoms like dizziness, lightheadedness after taking these medicines. Consider regular monitoring of blood pressure and sodium level.
What are you using Chloramphenicol 250 MG Capsule for?
Other
Edema
Hypertension
How much was the improvement?
Average
Excellent
How long did it take before seeing improvement?
More than 2 days
Within 2 hours
How frequently did you take this medicine?
Not taking on daily level
How did you take this medicine?
With Food
What were the side effects of this medicine?
Headache
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

HI, I would like to know that what purpose chloramphenicol 250 is used? Please suggest me.

BHMS, Diploma in Dermatology
Homeopath, Hyderabad
HI, I would like to know that what purpose chloramphenicol 250 is used? Please suggest me.
This medicine is used to treat infections caused by gram negative strains of bacteria which are severe and untreatable by other available medicines. Some of these infections are Bacterial meningitis, rickettsia, and others caused by susceptible organisms. Nov.
2 people found this helpful

What is the symptoms of typhoid fever. Chloramphenicol is best medicine for this or not?

C.S.C, D.C.H, M.B.B.S
General Physician, Alappuzha
Persons with typhoid fever usually have a sustained fever as high as 103° to 104° F (39° to 40° C). They may also feel weak, or have stomach pains, headache, or loss of appetite. In some cases, patients have a rash of flat, rose-colored spots. The only way to know for sure if an illness is typhoid fever is to have samples of stool or blood tested for the presence of Salmonella Typhi.

My mother who is 75 years old, has been found to have K.pneumonia in her throat swab which is sensitive to chloramphenicol. She does not have fever, but has unproductive cough and difficulty in swallowing when taking bigger pieces of food. Advise whether chloramphenicol can be given in a home setting.

International Academy of Classical Homeopathy, BHMS
Homeopath, Pune
My mother who is 75 years old, has been found to have K.pneumonia in her throat swab which is sensitive to chloramphe...
As homoeopath I would advise bioch asthm no 3 tabs 2tom day for19 days Kali.carb 12c 3tims a day for wk merc sol 12c 3tims day for 5 days spongia 6c 3tims a day for wk kalibich 200 one dose Ipecac 3c one dose day for 12 days inform me progress
1 person found this helpful

Popular Health Tips

Pinta - Know More About It!

Pinta - Know More About It!

Pinta is a skin disease caused by a bacterial infection. It is usually acquired during childhood and contracted through the skin to skin contact with an infected person. The disease is endemic to Mexico, Central America and South America. About One million of cases with Pinta were reported in Central and South America in the year 1950. The disease sets in within an incubation period of two to three weeks. It affects mostly the exposed areas of the skin including the arms, legs and face. The word ‘Pinta’ is a Spanish word which means ‘painted’. Pinta is classified under a treponemal disease because it is contagious and is caused by treponemes, a genus of spiral-shaped bacteria. Recent reports suggest the occurrence of disease in the Philippines and some areas of the pacific region.

The bacterium enters the skin through a cut, scratch or a lesion and causes a red scaly bump called the primary lesion. Other lesions may start to form surrounding the primary lesion usually in exposed surface of arms and legs. Local lymph nodes also become enlarged. Within three to nine months, these thick flat lesions called pintados spread all over the body. Sometimes the disease spreads to eyes causing eyelid deformities. The last stage of the disease is characterised by pigment changes in the skin including a combination of hyperpigmentation and depigmentation causing permanent discoloration. However, many patients get treated successfully before they reach the last stage.

Clinical Diagnosis of the infection is usually done through a blood sample showing bacterial infection or through diagnosing the scrapings of the lesion. The patient is subjected to an antibiotic treatment of drugs like penicillin, tetracycline, azithromycin and chloramphenicol. If prescribed dose of antibiotics is followed regularly, the cure is possible, however, skin damage caused due to lesions remain irreversible.

The disease is prevalent in rural and poverty-stricken areas and thus holds a strong connect with the socio-economic life of people. The living conditions, adequate water supply, domestic, personal and community hygiene, a proper waste disposal system and mosquito prevention and control play an important role in the prevention of the disease.

Prevention and control programs for Pinta must focus on awareness generation among high-risk groups. Though community hygiene is covered under many state health programs, for many communities, personal hygiene and the safe domestic environment remains far from satisfactory. Thus, first and foremost intervention must include building knowledge about maintaining proper hygiene and inculcating good habits for health and disease prevention. Since the disease is generally acquired in childhood, educating the parents about the early signs and symptoms of infection can also go a long way in ensuring that timely medical help is provided.

4250 people found this helpful

Conjunctivitis - How You Can Deal With It?

MBBS, MS - Ophthalmology
Ophthalmologist, Delhi
Conjunctivitis - How You Can Deal With It?

One of the most contagious infections to affect children and adults is conjunctivitis. Conjunctivitis, also known as pink eye is an inflammation of the conjunctiva. This makes the blood vessels of the eye more visible and turns the white part of the eye pinkish. This condition can be caused by a number of factors such as exposure to bacteria or viruses, allergens and irritants. Treatment for conjunctivitis depends on the cause of the condition.

The first step towards treating this disease is to correctly diagnose it. Some of the symptoms that can be noticed are:

  1. Redness in the white of the eye
  2. Itchiness and burning in the eye
  3. Discharge from the eye
  4. Crusting of the eyelids
  5. Increased sensitivity to light

If you notice any of these symptoms persisting for over a few days, consult a doctor immediately. There are two aspects to dealing with conjunctivitis; preventing the infection from spreading and reducing the infection. Here are a few tips to help stop the infection from spreading.

  1. Stop wearing contact lenses. While the infection persists, wear spectacles instead. Once your eyes have healed, dispose of the old contacts lenses and solution and get yourself a new pair.
  2. Wash your hands often. This is especially important if you have touched your eyes and will prevent the infection from spreading.
  3. Avoid sharing contact lenses, eye makeup and other forms of makeup along with makeup brushes.
  4. Avoid rubbing your eyes. Often conjunctivitis can affect only one eye at a time. Keeping yourself from rubbing or touching the infected eye will keep the infection from spreading to the other eye.
  5. Remove the discharge from around your eye every few hours with a clean cotton swab. Throw the swab away after it has been used once and wash your hands with soap and water before touching anything else.
  6. Avoid using swimming pools and hot tubs.
  7. Wash towels. Pillow cases, sheets and other things that come in regular contact with your eyes every few days with hot water to disinfect them.

In most cases of infective conjunctivitis, antibiotics are not needed. Instead lubricant eye drops are prescribed that are available over the counter. This can help ease soreness and stickiness in the eye. When using lubricant eye drops, do not let the dropper touch the infected eye and do not use the same eye drops for both eyes. Untreated conjunctivitis can be treated with antibiotics such as chloramphenicol and fusidic acid. These antibiotics can have a few side effects such as blurred vision and hence you must avoid driving and operating heavy machinery after using them. If you wish to discuss about any specific problem, you can consult an Ophthalmologist.

4434 people found this helpful

All You Want To Know About Pinta

Diploma In Dermatologist, Venereologist and Laparoscopy, MBBS
Dermatologist, Rewari
All You Want To Know About Pinta

Pinta is a skin disease caused by a bacterial infection. It is usually acquired during childhood and contracted through the skin to skin contact with an infected person. The disease is endemic to Mexico, Central America and South America. About One million of cases with Pinta were reported in Central and South America in the year 1950. The disease sets in within an incubation period of two to three weeks. It affects mostly the exposed areas of the skin including the arms, legs and face. The word ‘Pinta’ is a Spanish word which means ‘painted’. Pinta is classified under a treponemal disease because it is contagious and is caused by treponemes, a genus of spiral-shaped bacteria. Recent reports suggest the occurrence of disease in the Philippines and some areas of the pacific region.

The bacterium enters the skin through a cut, scratch or a lesion and causes a red scaly bump called the primary lesion. Other lesions may start to form surrounding the primary lesion usually in exposed surface of arms and legs. Local lymph nodes also become enlarged. Within three to nine months, these thick flat lesions called pintados spread all over the body. Sometimes the disease spreads to eyes causing eyelid deformities. The last stage of the disease is characterised by pigment changes in the skin including a combination of hyperpigmentation and depigmentation causing permanent discoloration. However, many patients get treated successfully before they reach the last stage.

Clinical Diagnosis of the infection is usually done through a blood sample showing bacterial infection or through diagnosing the scrapings of the lesion. The patient is subjected to an antibiotic treatment of drugs like penicillin, tetracycline, azithromycin and chloramphenicol. If prescribed dose of antibiotics is followed regularly, the cure is possible, however, skin damage caused due to lesions remain irreversible.

The disease is prevalent in rural and poverty-stricken areas and thus holds a strong connect with the socio-economic life of people. The living conditions, adequate water supply, domestic, personal and community hygiene, a proper waste disposal system and mosquito prevention and control play an important role in the prevention of the disease.

Prevention and control programs for Pinta must focus on awareness generation among high-risk groups. Though community hygiene is covered under many state health programs, for many communities, personal hygiene and the safe domestic environment remains far from satisfactory. Thus, first and foremost intervention must include building knowledge about maintaining proper hygiene and inculcating good habits for health and disease prevention. Since the disease is generally acquired in childhood, educating the parents about the early signs and symptoms of infection can also go a long way in ensuring that timely medical help is provided. If you wish to discuss about any specific problem, you can consult a doctor and ask a free question.

2591 people found this helpful

All About Typhoid Fever!

MBBS
General Physician, Chittorgarh

What is typhoid fever?
Typhoid fever or enteric fever is a digestive tract infection in which there is fever, headache, and abdominal pain or discomfort. It is very common in developing countries like india.

What are the causes and risk factors?
Typhoid fever is caused by a bacterium called salmonella typhi which is transmitted through contaminated water or food (feco-oral or urine-oral route).

Risk factors include:

  • Travelling to areas where typhoid fever is a common disease.
  • Being in a profession where contamination with bacteria is likely. Like those working in laboratories.
  • Coming in close contact with a person suffering from typhoid.
  • Drinking/ eating contaminated water or food.

How will you know if you have typhoid fever?
Signs and symptoms develop gradually over the period of 10-14 days after exposure to the bacteria.
Signs and symptoms include an irregular fever that can go up to 104.9 ˚f (40.5 ˚c), headache, pain in abdomen, tiredness, muscle pain, loss of appetite, nausea, constipation or diarrhoea, skin rash.

How is typhoid fever diagnosed?
Your doctor will do a physical examination and carry out some tests.
Physical findings in early stages include abdominal tenderness, enlarged spleen and liver, enlarged lymph nodes, and development of a rash (also known as rose spots because of their appearance).

Investigations include:

  • Blood tests: typhidot test igm and igg antibodies, blood culture to test for salmonella typhi.
  • Stool and urine analysis
  • Bone marrow culture: it is the most sensitive test, but it is rarely required except in patients who have already received antibiotics and not getting any better.
  • Widal antigen test: this test can be done, but there is a longer waiting phase of about 10 days till results can be seen, it is time-consuming and could give false positive results.

What is the treatment for typhoid fever?

What are the complications of typhoid fever?
If not treated and sometimes even after treatment, there can be serious complications due to typhoid like pneumonia, meningitis (inflammation of meninges of brain), infection in bones (osteomyelitis), intestinal perforation and intestinal haemorrhage.

A doctor needs to be consulted if a person starts developing the symptoms few days after travelling to a place where typhoid is prevalent.

How can typhoid fever be prevented?

  • Typhoid fever can be prevented by improving sanitation facilities and drinking clean drinking water.
  • Always wash your hands with soap and warm water after using restrooms, before eating or cooking food.
  • Maintaining optimum personal hygiene is the key to preventing this disease.
  • Travellers should not drink untreated water; avoid adding ice to their drinks and should not eat ice creams or milk products or street foods that are a rich source of the infection.
  • Vaccines are available that give partial protection. Vaccines usually are reserved for those who may be exposed to the disease or are travelling to areas where typhoid fever is common.
15 people found this helpful

Michael Jackson Vitiligo - Know All About It!

MD - Homeopathy, BHMS
Homeopath, Ghaziabad
Michael Jackson Vitiligo - Know All About It!

I have successfully treated highest number of Leucoderma and Vitiligo patients in India since past 32 years. Homoeopathy along with holistic modes has been a miraculous aid in giving the results. In this article, I bring to you the topic of a famous personality and his confrontation with Vitiligo. 

  • Michael Jackson songs, the king of pop, thriller, moonwalk getting nostalgic? We all remember Michael Jackson as the king of pop, he stirred up the ear with his over the top songs and breathtaking dance moves! His death shook the world and the music industry at large.
  • He always had been the talk of the town not only for his art but for his appearance.
  • Michael Jackson skin color raised controversies and questions among fans and fellow artists. He was accused of skin bleaching and using various techniques to turn white because he didn’t like his skin color. However he shunned these allegations by admitting to having Vitiligo on Oprah Winfrey’s show.

Vitiligo is an autoimmune skin disorder which causes loss of pigment in the skin. The melanin production capacity of the skin gets dysfunctional. This causes white patches on skin which can spread like it did on Michael Jackson. Due to less awareness of Vitiligo back then everyone believed that Michael Jackson was making up a story to cover the allegations of skin bleaching.

Only 2% of the world’s population suffers from Vitiligo and Jackson had a paternal history of the disease which was dominant in his case.

Vitiligo began on Michael Jackson’s skin soon after Thriller album, it started off as white dots on his hands skin which he covered with Billie Jean Gloves. But, in no time it spread over his full hand and body, he initially tried to cover it with full coverage makeup but it did him no good as patches begin to grow. When the disease went out of control, he opened up about his condition.

Though harmless otherwise these white patches become a cause of embarrassment and low self esteem in highly pigmented individuals like Michael Jackson himself. He was born a black american but in his adulthood his skin turned white. He fell a prey to innumerous allegations and racist comments because of the lack of knowledge among the people. Michael Jackson Vitiligo was confirmed in a biopsy report and was made public thus proving he really did have vitiligo.

Who all can have Vitiligo?

Vitiligo rarely shows familial history but this factor cannot be ruled out. It can affect people of any age group, race or sex. Vitiligo is generally more prominent in countries like India, Egypt and other tropical countries. Many cases have seen its onset after menopause, at 15 years of age, or as early as the age of 5. Vitiligo is non infectious and non-contagious and cannot spread with touch. It has no relationship to leprosy, however there can be differential diagnosis of seeing white patches on skin.

What can cause Vitiligo?

Exact causes of vitiligo have not been established yet but it can be due to gastrointestinal disorder like chronic amoebiasis, chronic dyspepsia and intestinal worms may be additional factors.

Trauma or local irritation from wearing tight blouses and clothes can also produce Vitiligo in individuals predisposed to it. Acute stress may be followed by fast spreading vitiligo. Endocrine disorders or nutritional disorders can also be revolving cause for Vitiligo.Not infrequently it has been seen vitiligo appearing after use of broad-spectrum antibiotics esp chloramphenicol and streptomycin.

How to treat Vitiligo?

In Michael Jackson’s case he matched his unaffected skin color with the vitiligo skin color by going a shade lighter which made him appear completely white. However with the advancement over years it is possible to treat vitiligo.

For stationary and small patches there are temporary options to dye the white patch into the skin color. It is done by doing a patch test and seeing which color is absorbed by the skin.

Whereas for a permanent long time solution it is important to treat this condition constitutionally by promoting the production of melanin internally by medicines.

  • Some local applications and frequent sun exposure on the patches can also help in repigmentation.

  • Avoid eating food from animal sources.

  • It is extremely important to keep your skin and yourself hydrated as Vitiligo paired up with other disorders like diabetes can cause dehydration very soon.

  • Avoid wearing tight clothes and prevent trauma on skin.

  • Do not stress as it can also contribute in producing vitiligo.

  • Apply pure ghee with turmeric on white patches and take sun exposure.

At Valeda, you can avail a holistic treatment to cure Vitiligo permanently by constitutional medicines and total wellness using techniques of acupuncture that will strengthen your immune system and also treat your Vitiligo Skin. If you wish to discuss about any specific problem, you can consult a Homeopath.

4633 people found this helpful

Table of Content

About Chloramphenicol 250 MG Capsule
When is Chloramphenicol 250 MG Capsule prescribed?
What are the contraindications of Chloramphenicol 250 MG Capsule?
What are the side effects of Chloramphenicol 250 MG Capsule?
Key highlights of Chloramphenicol 250 MG Capsule
What are the substitutes for Chloramphenicol 250 MG Capsule?
What are the dosage instructions?
Where is the Chloramphenicol 250 MG Capsule approved?
What are the interactions for Chloramphenicol 250 MG Capsule?