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Klorum 250 MG Capsule

Manufacturer: Zydus Cadila
Medicine composition: Furosemide
Prescription vs.OTC: Prescription by Doctor required
Last Updated: October 27, 2020

Klorum 250 MG Capsule is primarily used for the management of oedema associated with congestive heart failure and hepatic or renal disease; alone or in combination with antihypertensives in treatment of hypertension.

Klorum 250 MG Capsule is known to be a loop diuretic, also known as a water pill. The drug when taken reduces the amount of salt that the body absorbs. The excess salt is then excreted by the body through the urine.

The drug is used to control fluid retention in the body of patients suffering from liver disease, kidney problems and congestive heart failure. Thus, the drug helps in the creation of more urine which gets rid of excess fluid and salt produced in the body.

You can take this medicine orally with a meal or without. Try not to take the drug around your bedtime so as to prevent the urge to urinate throughout the night. The dosage prescribed, usually depends on your age, your health and your body’s response to the drug.

In case of children the dosage is also determined according to their weight. You doctor will first start you off with a low dose to see how your body accepts the drug. If you do not develop any side effects he may increase the dosage.

Side effects are a common occurrence when you take any medication. While some side effects are quite common and disappear as your body adjusts to the drug, others are more severe and can create complications. Klorum 250 MG Capsule can cause some minor side effects like dizziness, problems with vision, headache and faint feeling. If you do experience dizziness, ensure that you move slowly to avoid any accidents.

Klorum 250 MG Capsule can result in severe dehydration as it creates the need to urinate frequently. Very rarely do patients suffer from an allergic reaction to Klorum 250 MG Capsule. But if it does occur consult your doctor and get the treatment done.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Urologist before using this medicine.

The primary use of this medication is as follows:

  • Hypertension

  • Congestive Heart Failure (Chf)

  • Edema (Swelling)

Side effects that might occur after the consumption of this medicine include:

  • How long is the duration of effect?

    The effect of this medicine lasts for an average duration of 6 to 8 hours after an oral dose and 2 hours after an intravenous dose.
  • What is the onset of action?

    The effect of this medicine can be observed in 30 to 60 minutes after an oral dose, 30 minutes after an intramuscular dose and 5 min after an intravenous dose.
  • Are there any pregnancy warnings?

    This medicine is not recommended for pregnant women.
  • Is it habit forming?

    No habit forming tendency has been reported.
  • Are there any breast-feeding warnings?

    This medicine is not recommended for women who are breastfeeding.
  • Does this affect kidney function?

    Caution must be taken in patient with renal disease. Adjustment of dose is needed. Kindly consult your doctor before taking it.
  • Does this affect liver function?

    Caution must be taken in patient with liver disease. Adjustment of dose is needed. Kindly consult your doctor before taking it.

Below is the list of medicines, which have the same composition, strength and form as Klorum 250 MG Capsule , and hence can be used as its substitute.

  • Missed Dose instructions

    The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.
  • Overdose instructions

    Seek emergency medical treatment or contact the doctor in case of overdose.
  • Missed Dose instructions

    The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.
  • Overdose instructions

    Seek emergency medical treatment or contact the doctor in case of overdose.
  • India

  • United States

  • Japan

  • India

  • United States

  • Japan

This medication works by blocking the sodium-potassium-chloride cotransporter (NKCC2) in the ascending limb of the loop of Henle. This, in turn, prevents sodium, potassium and chloride from being absorbed which increases urine output.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Alcohol

    Alcohol

    Consumption of alcohol is not recommended while you are taking this medicine. It may increase the risk of dizziness and fainting. Avoid performing activities that need mental alertness like operating machinery or driving a vehicle.
  • Interaction with Lab Test

    Lab

    Information not available.
  • Interaction with Medicine

    • ACE inhibitors: Hypotensive effects and/or renal effects are potentiated by hypovolemia.
    • Antidiabetic agents: Glucose tolerance may be decreased.
    • Antihypertensive agents: Hypotensive effects may be enhanced.
    • Cephaloridine or cephalexin: Nephrotoxicity may occur.
    • Cholestyramine or colestipol may reduce bioavailability of furosemide.
    • Clofibrate: Protein binding may be altered in hypoalbuminemic patients receiving furosemide, potentially increasing toxicity.
    • Digoxin: Furosemide-induced hypokalemia may predispose to digoxin toxicity. Monitor potassium.
    • Indomethacin (and other NSAIDs) may reduce natriuretic and hypotensive effects of furosemide.
    • Lithium: Renal clearance may be reduced. Isolated reports of lithium toxicity have occurred; monitor lithium levels.
    • Metformin may decrease furosemide concentrations.
    • Metformin blood levels may be increased by furosemide.
    • NSAIDs: Risk of renal impairment may increase when used in conjunction with furosemide.
    • Ototoxic drugs (aminoglycosides, cis-platinum): Concomitant use of furosemide may increase risk of ototoxicity, especially in patients with renal dysfunction.
    • Peripheral adrenergic-blocking drugs or ganglionic blockers: Effects may be increased.
    • Phenobarbital or phenytoin may reduce diuretic response to furosemide.
    • Salicylates (high-dose) with furosemide may predispose patients to salicylate toxicity due to reduced renal excretion or alter renal function.
    • Sparfloxacin, gatifloxacin, and moxifloxacin: Risk of hypokalemia and cardiotoxicity may be increased Avoid use.
    • Succinylcholine: Action may be potentiated by furosemide.
    • Sucralfate may limit absorption of furosemide, effects may be significantly decreased; separate oral administration by 2 hours.
    • Thiazides: Synergistic diuretic effects occur.
    • Tubocurarine: The skeletal muscle-relaxing effect may be attenuated by furosemide.
  • Interaction with Food

    Food

    Information not available.
  • Interaction with Disease

    • Adjust dose to avoid dehydration.
    • In cirrhosis, avoid electrolyte and acid/base imbalances that might lead to hepatic encephalopathy.
    • Ototoxicity is associated with rapid I.V. administration, renal impairment, excessive doses, and concurrent use of other ototoxins.
    • Hypersensitivity reactions can rarely occur.
    • Monitor fluid status and renal function in an attempt to prevent oliguria, azotemia, and reversible increases in BUN and creatinine. Close medical supervision of aggressive diuresis required.
    • Monitor closely for electrolyte imbalances particularly hypokalemia. Watch for and correct electrolyte disturbances.

Ques: What is Klorum 250 MG Capsule?

Ans: Klorum 250 MG Capsule is known to be a loop diuretic, also known as a water pill. The drug when taken reduces the amount of salt that the body absorbs. The excess salt is then excreted by the body through the urine.

Ques: Is there any difference between Klorum 250 MG Capsule and Torasemide?

Ans: Klorum 250 MG Capsule and Torasemide are both loop diuretics and they both are used for treatment of high blood pressure and also edema which is caused by underlying liver, lung or kidney disease. The difference between the two is that Klorum 250 MG Capsule is used in treating high calcium levels in blood whereas Torasemide does not treat that.

Ques: Should you drink a lot of water when taking Klorum 250 MG Capsule?

Ans: An adequate amount of water intake is advised while taking Klorum 250 MG Capsule. The reason behind this is that it eliminates the extra fluid and electrolytes from the body by excessive urine production.

Ques: Can Klorum 250 MG Capsule cause weight gain?

Ans: No, in fact the opposite can happen and you can lose weight as your body gets rid of excessive fluid by the consumption of it.

Ques: What are the side effects of overdose of Klorum 250 MG Capsule?

Ans: If this medicine is consumed in overdose, then you might have to suffer some side effects. The side effects include irregular heartbeat, dizziness, headache, and temporary unconsciousness.

Ques: For what period of time should I take Klorum 250 MG Capsule?

Ans: The medicine should be taken until you feel fine. The dosage instructions must be taken by the concerned doctor.

Ques: What other lifestyle changes should I make while taking Klorum 250 MG Capsule?

Ans: Exercising regularly, Consumption of healthy food and prohibition of smoking and drinking are some basic lifestyle changes that should be adopted. Otherwise, you should consult your doctor.

Ques: Should I stop the consumption of Klorum 250 MG Capsule if my BP is in control?

Ans: Sudden discontinuation of medication could result in rise in blood pressure and the chances of stroke or heart attack could also increase. Doctor should be consulted for dosage advice.

Ques: What if I have missed a dose of Klorum 250 MG Capsule?

Ans: The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

Ques: Is it necessary to take Klorum 250 MG Capsule with the food?

Ans: You can take it with or without the food.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Table of Content
About Klorum 250 MG Capsule
What are the uses of Klorum 250 MG Capsule
What are the contraindications of Klorum 250 MG Capsule ?
What are the side effects of Klorum 250 MG Capsule ?
Key highlights of Klorum 250 MG Capsule
What are the substitutes for Klorum 250 MG Capsule ?
What are the dosage instructions?
Where is the Klorum 250 MG Capsule approved?
How does this medication work?
What are the interactions of Klorum 250 MG Capsule ?
FAQs about Klorum 250 MG Capsule