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Bolstran 150mg Injection

Manufacturer: Cipla Ltd
Medicine composition: Omalizumab
Prescription vs.OTC: Prescription by Doctor required

Bolstran 150mg Injection aids in the treatment of asthma and chronic idiopathic urticaria (CIU). It may be prescribed to asthma patients of 6 years and above. It helps in the treatment of moderate to even severe asthma. Although, it will not help to treat other types of allergies and acute bronchospasm. The drug is meant to treat CIU in adults as well as children above the age of 12 years.

To treat asthma, about 75 mg to 375 mg of the drug may be administered in the form of an injection every couple of weeks. In case of adults the dosage may vary as per the weight of the patient.

To treat CIU, about 150 mg to 300 mg of the drug may be administered in the form of an injection every 4 weeks. Treatment with the drug may be continued unless sufficient improvement is witnessed in the patient.

Like all other medicines, the intake of Bolstran 150mg Injection also leads to some side effects such as dizziness, fatigue, pain in the arms and legs, fractures and dermatitis. If you do experience any of these problems, get in touch with your doctor and seek relevant treatment.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Pulmonologist before using this medicine.

In addition to its intended effect, Bolstran 150mg Injection may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Is It safe with alcohol?

There is no data available. Please consult doctor before consuming the drug.

Are there any pregnancy warnings?

There is no data available. Please consult doctor before consuming the drug.

Are there any breast-feeding warnings?

There is no data available. Please consult doctor before consuming the drug.

Is it safe to drive while on this medicine?

There is no data available. Please consult doctor before consuming the drug.

Does this affect kidney function?

There is no data available. Please consult doctor before consuming the drug.

Does this affect liver function?

There is no data available. Please consult doctor before consuming the drug.
Below is the list of medicines, which have the same composition, strength and form as Bolstran 150mg Injection , and hence can be used as its substitute.
Novartis India Ltd
Bolstran 150mg Injection It is an anti-asthma drug that prevents the binding of IgE to the IgE receptor (high affinity) on the surface of mast cells and basophils. As a result the intensity of production of the mediators of allergic response is reduced.
What are you using Bolstran 150mg Injection for?
asthma and chronic idiopathic urticaria
How much was the improvement?
How long did it take before seeing improvement?
More than 2 days
Within 2 hours
How frequently did you take this medicine?
Not taking on daily level
How did you take this medicine?
With Food
With or without food
What were the side effects of this medicine?
Abdominal Pain
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

Sir mein chronic urticaria ki patient omalizumab injection par depend hoo but koi improve ment nahi high ige level level kuch food allergy aur dust ,dust mite etc allergy hai complexion bhi bahoot dull hogaya hai doctor boli allergy hi karan hai air face. Neck ,hand sab par bade black patches hogaya hai iska karan bhi doctor allergy ko bole hai. Mujhko ek ayurveda, homeopathy,allopathy doctor sab dekh chuke hai but no improvement. Please koi best prescription de kaise khayu kitna din tak please sir detail mein reply de.

Homeopath, Noida
For complexion you can do this. But for urticaria you need to take proper treatment. You can apply aloe vera juice/gel from its leaf (fresh), not from ready made gels available in market. Remove skin of an aloe vera leaf. Take /scoop out gel. Apply this gel to your skin. Wash with plain water after an hour. Or keep it overnight. Use some sunblock with spf (at least 50) every time you go out in sun. Apply it 30 mins before going out use umbrella when going in sun. U need proper constitutional med to get permanent relief. Ask for consultation so that I can help you better.

I have problem of hives. Can I get relief from this. If possible then please help me. I am very thankful to you. I went to many doctor .but I found nothing regarding my problem,

M.D. Consultant Pathologist, CCEBDM Diabetes, PGDS Sexology USA, CCMTD Thyroid, ACDMC Heart Disease, CCMH Hypertension, ECG
Sexologist, Sri Ganganagar
I have problem of hives. Can I get relief from this. If possible then please help me. I am very thankful to you. I we...
When antihistamines don't provide relief, oral corticosteroids may be prescribed. A biologic drug, omalizumab (Xolair), is also approved to treat chronic hives in those at least 12 years of age. For severe hive or angioedema outbreaks, an injection of epinephrine (adrenaline) or a cortisone medication may be needed.
2 people found this helpful

Sir I am being suffering from allergy since last 20 days , I had taken consultation and doctor only prescribed me the medicines like atrax 25 mg and elina. But I am not getting cured properly. Mostly this itching and iritation ocvurs in the midnight. Please suggest. Thanks and regards

FCCP (USA), MD - Pulmonary Medicine
Pulmonologist, Indore
You can get allergic testing done at a good centre. There after if found allergic to one or two substances then can get relief by immunotherapy. Another option is get total IgE done. If the level is high you will benefit by anti IgE called Omalizumab. This has been recently approved in USA for allergic urticaria.

Hi doctor I am suffering from urticaria from last 6 years. Is any side effect of this disease for future. And how I get rid from this. Is this natural. Or life time problem?

General Physician, Hisar
Hi doctor I am suffering from urticaria from last 6 years. Is any side effect of this disease for future. And how I g...
Hi lybrate-user, Urticaria is a common form of skin allergic reaction and it is unfortunate that we can not find the certain major cause of it so that's why we call it idiopathic. Now coming on to its treatment options- 1 Primary prevention would be to complete avoid aggravating factors like some dietary habits, alcohol, heat, mental stress and friction area. 2 Antihistamines like cetrizine Leukotriene receptor antagonists 3 Steroids like prednisolone 4Sulfasalazine and a host of immunosuppressives like methotrexate, cyclosporine, omalizumab etc. 5. Avoid Aspirin and any NSAID or you can say painkillers as they may be harmful.

Popular Health Tips

World Asthma Day - Spreading Awareness Is Important!

M.D - Respiratory Medicine
Pulmonologist, Hyderabad
World Asthma Day - Spreading Awareness Is Important!

Most people know all about Asthma, how dangerous it is and most importantly, with the rising levels of pollution and irritants how people are getting affected by it all over the world. Just like famous events, incidents and festivals have their special date in the calendar, May 1 apart from being the International Labour Day, holds another significant stance worldwide. As it is celebrated as the World Asthma Day. This day marks the initiation of the Asthma awareness campaign worldwide.

Understanding Asthma in brief

Asthma is a long-term respiratory condition, in which the airways of the human system may unexpectedly and suddenly narrow, often in response to an allergen, cold air, exercise or emotional stress. Common symptoms include wheezing, shortness of breath, chest tightness, and coughing.

Why is Asthma Day important?

World Asthma Day is celebrated every year on the first Tuesday of May. This year it falls on 1st May. The day is celebrated to spread awareness about Asthma and how people all over the world can spread it amongst their families. Therefore to commemorate the event and educate the students in school and parents at home, World Asthma day was commenced. The aim of this campaign is to make people understand the types of Asthma that can affect them and immediate safety tips so as to ensure that the severity of the disease can be curtailed. 

Things to keep in mind about Asthma

All over the world, there are several people who do not opt for Asthma treatment and that proves to be a fatal mistake later on in life. Chronic Asthma disease can be easily prevented by a simple treatment in the initial stages. People who suffer from Asthma often face chronic attacks if they forget to carry their inhaler and different kinds of allergies are also very fatal for asthma people.

Things that can trigger Asthma in people

  1. Dust 
  2. Pollens
  3. Gastroesophageal Reflux
  4. Pet Dander
  5. Certain foods 
  6. Exposure to chemicals 
  7. Excessive physical activity 
  8. Stress 
  9. 39-50% Of Sinusitis patients have Asthma also 
  10. Extremely cold conditions

Signs someone is suffering from Asthma 

  1. Persistent coughing
  2. Difficulty in breathing
  3. Wheezing 
  4. Tightness in chest

Diagnosis and severity are established by a simple air blowing test known as Spirometry.

  • Chest X-ray and Sinus X-ray Help 
  • Serum IgE a blood test tells about type and severity

Severe cases may require special blood test known as Arterial Blood Gases to look at blood oxygen and carbon dioxide.

Sheet anchor of therapy is the inhaled medication to dilate airway and to reduce inflammation. The dose being in microgram dose is harmless and delivered to the site of the problem.  New drugs known as Omalizumab and Benralizumab are approved for specific nonresponding patients with severe asthma.

Prevent asthma from being harmful

Asthma is a chronic disease can stay for the rest of someone's life. So on this World Asthma Day make sure that you know how it can be treated and prevent the disease from harming someone you love. Here are some treatment tips.

  1. First get to know more about asthma and become a partner with the doctor to carry out treatment for a long time period.
  2. Be aware of the allergens that may trigger asthma and prevent them from coming in contact with the person.
  3. Make sure to keep the doctor updated regarding the status of a patient's condition and for any sign of potential risk.
  4. If a loved one is suffering then ensure that they lead their life as per the guidelines shared by the doctor, in order to prevent any risky situation. 

So here are the important things that you should be knowing about asthma. And, in case you notice any of the symptoms mentioned above, one should immediately contact their doctor. On this World Asthma Day be aware of the disease and keep the people safe who are suffering from it. Stay Healthy!

In case you have a concern or query you can always consult an expert & get answers to your questions!

3331 people found this helpful

Asthma - All About It!

MD - Acupuncture, Diploma In Accupuncture, Advanced Diploma In Accupuncture
Acupuncturist, Delhi
Asthma - All About It!

The word "asthma" originates from the Greek word, ásthma that means, "panting.” Asthma is a medical condition in which the airways swells and produces extra mucus that can make breathing difficult. Because of the inflammation and the extra mucus, it can trigger shortness of breath and wheeze or coughing.

Documented as early as Ancient Egypt, Asthma can be either a minor nuisance or life-threatening. In asthma, the inside walls of the airways get inflamed so that lesser air can pass through them from and to the lungs making breathing a difficult exercise. This swelling can also make the airways really sensitive and increase a person’s susceptibility to allergic reactions.

Asthma has been on the rise significantly since the 1960s and now according to WHO estimate, around 300 million people suffer from asthma worldwide. In fact Asthma is one of the most common chronic childhood illness.

Symptoms of Asthma-
The symptoms of asthma vary. But what most people with asthma have in common is the extreme airway sensitivity because of triggered airway inflammation. Some people have frequent asthma attacks, some people experience asthma only during certain times, some people have it all the time and some people only experience it infrequently.

Common asthma signs and symptoms include:
-  Wheezing or coughing

-  Shallow breathing

-  Breathlessness

-  Chest pain

-  Throat infection

-  Faster heart rate

-  Trouble in sleeping

-  Difficulty in speaking

Types of Asthma-
Normally people suffering from an asthma attack tend to have a whistling or wheezing sound when exhaling. There are different types of asthma. Some of the most common types of asthma are: 

1. Exercise-induced asthma 
Also called exercise-induced bronchoconstriction, this type of asthma is induced by strenuous exercises and can cause symptoms like coughing, wheezing, shortness or breath and other symptoms. These symptoms may worsen when the air is dry and cold and usually get triggered during or after an exercise.

2. Occupational asthma 
As the name suggests, occupational asthma is triggered by breathing in certain chemical fumes, dust, gases, or other kinds of exposure to allergens at the workplace.

3. Allergy-induced asthma 
Allergy-induced asthma is the most common type of asthma, which is triggered by common airborne allergens like pollen, mold spores, dust mites, or particles of skin.

What Are Causes of Asthma?
Although the causes are not particularly clear and anyone can get asthma at any age, it is more common childhood ailment. The studies are still underway to prove a clear asthma cause but according to the researches this disease is believed to be caused by a blend of genetic and environmental factors. Genomics, which is the study of how a person’s genes interrelate with environmental factors, may be the key to understanding why certain people are more prone to asthma than others.

Asthma Triggers-
Asthma triggers can differ from person to person and the key is to know what irritants trigger your asthma to ensure minimized exposure to it. Some generic asthma signs and symptoms can include:

-  Cold air

-  Exercise and other physical activities

-  Common cold and other respiratory infections

-  Stress

-  Airborne substances like pollen, mold spores, pet dander, cockroach waste, dust mites, etc.

-  Airborne substances, such as pollen, dust mites, mold spores, pet dander

-  Certain chemicals and air pollutants (smoke)

-  Certain preservatives (added to food and beverages)

-  Gastroesophageal reflux disease (GERD)

-  Certain medicines like aspirin, ibuprofen, etc.

Risk factors-
There are several risk factors that can increase your chances of developing asthma including:

-  Genetics. Having a family especially a blood relative suffering from asthma

-  Having other allergic condition (hay fever)

-  Smoking

-  Exposure to secondary smoking

-  Obesity (people who are overweight are at a greater risk of developing asthma)

-  Exposure to increasing amount of smoke or other pollutants

-  Occupational triggers

-  Stress and anxiety

Diagnosis of Asthma-
Even though it is a common childhood disease, it doesn’t mean, as an adult one cannot develop it. If a person is feeling any of the symptoms whether a child or an adult, it is always a good idea to get checked to know for sure if you have asthma. Asthma symptoms can come and go since it is a ‘variable’ disease.

It is also important to not do self-diagnosis, as some symptoms, which may look like asthma triggers, may not be actually asthma-like persistent cough caused by other diseases like certain heart diseases and chronic obstructive pulmonary disease (COPD).

Effective diagnosis of Asthma depends upon its classification. There are four different classifications of Asthma:

Classification of Asthma
-  Mild intermittent – It is a mild case of asthma if the symptoms last only for up to two days a week, symptoms flaring up mainly at night and asthma lasting not more than two nights in a month.

-  Mild persistent – Mild persistent asthma is when the symptoms can occur twice in a week but not more than one episode per day.

-  Moderate persistent – This happens when a person experiences symptoms once a day and in excess of one night a week.

-  Severe persistent - Symptoms can last throughout the day and frequently at night on most days.

Diagnosis of Asthma
1. Physical test

The doctor would want to rule out other possible condition through a physical exam to get to know the signs and symptoms.

Some lung function tests can help in determining how the lung in functioning in a person.

2. Spirometry
One of the most common pulmonary function tests, spirometry measures lung function by checking the amount of air a person can inhale and exhale after deep breaths.

3. Peak flow
The peak expiratory flow is a pulmonary device that can measure the maximum speed one can breathe out. If the readings are low, it may be a sign that the person’s lungs are not working properly and could be a potential sign of asthma.

These tests can be done with a medicine called as bronchodilator (albuterol) to check if the lung functions better with the medication. If the test gets better after the use of bronchodilator, then it is highly likely for a person to suffer from asthma

Additional tests and Diagnosis For Asthma
Other tests that may be required to diagnose asthma include:

1. Methacholine challenge-
Methacholine is considered an asthma trigger and so when it is inhaled it can cause mild constriction of the airways. Most people who have asthma are likely to react to methacholine. Doctor could use this test to determine whether you have asthma.

2. Imaging tests-
Certain imaging tests like x-rays and CT scan can help in identifying certain abnormalities that might be causing breathing issues.

3. Allergy testing-
Most allergy tests can help in identifying allergy to triggers like pollen, dust, etc.

4. Sputum eosinophils-
This test can help in identifying the while blood cells in the mucus to see if asthma is present or not.

5. Nitric oxide test-
For people whose airways are inflamed, they may have higher nitric oxide level than normal which may be able to help in identifying whether the person is suffering from asthma or not.

7. Provocative testing for exercise and cold-induced asthma-
As the name suggests, in this a person is made to perform vigorous physical activities in a controlled environment to check for the triggers.

Treatment of Asthma-
Although there is no known cure available for asthma and it is generally a life-long condition, treatment can control asthma symptoms so a person can lead a normal life. Also when it comes to asthma, there is no one-size fit all treatment methodology. The idea is to understand the triggers that worsen your symptoms, taking steps to avoid them and taking the medication on time to keep asthma in check.

1. Inhalers 
Inhalers are medical devices, which are used for supplying medication into the body through the lungs. There are three types of inhalers. These are:

-  Reliever Inhalers: These inhalers are used for the purpose of relieving symptoms at the time of asthma attack. Normally reliever inhalers don’t have many side effects, in some people they may increase heart beat and induce shaking. 

-  Preventive Inhalers: True to their name, this types of inhalers are used to stop the symptoms from developing.

-  Combination Inhalers: If either of these kinds of inhalers doesn’t work for a person, they would need an inhaler that would both relieve the attack and prevent it from happening again.

2. Tablets -
If inhalers don’t work to control the symptoms, one may also use tablets.

Leukotriene receptor antagonists (LTRAs) 
LTRAs are the oral tablets prescribed for asthma and are also available in syrup and powder forms. It can be taken every day without many side effects. However, some people may experience some side effects including headaches and stomach pain.

If LTRAs tablets cannot be prescribed for some reasons or is not working, doctors may also prescribe Theophylline. It should be taken every day.

  • Steroid tablets-

Steroid tablets are given to give relief from an asthma attack. Long-term usage of steroid tablets for is not recommended unless a person is suffering from severe asthma and if inhalers aren’t handy controlling the symptoms. Some possible side effects of using steroid tablets for long-term are mood swings, fragile bones, high blood pressure, etc.


Other treatments for Asthma
Other treatments like surgery or injections may be required in case other treatments don’t work for a person.

For certain people with severe asthma, some injections like omalizumab, mepolizumab, or reslizumab may be able control the symptoms. For some severe asthma patients, injections are prescribed every few weeks in order to control the symptoms. However, these injections should be taken only under the prescription from an asthma specialist, as these injections may are not advisable for every asthma patient.

For some people for whom treatments like inhalers, tablets, and injections don’t work or in certain cases cannot be administered, a surgical procedure called bronchial thermoplasty can be used. In this treatment, a flexible thin tube is passed down the throat into the lungs and heat is used to warm up muscles surrounding the air controlling nerves to stop causing asthma-like symptoms.

However, this process is fairly new and so much research has not been done on its long-term relief.

Complementary therapies 
There are many complementary therapies that can help ease the symptoms, prevent asthma from happening, and help strengthen the lungs and the airway muscles. However, before incorporating any of these therapies in your lifestyle, it is always best to check with your asthma specialist first. These therapies include

Certain breathing exercises including yoga
-  Alternative medicines like homeopathy, chiropractic, and Ayurveda

-  Dietary supplements

-  Acupuncture

-  Certain traditional Chinese medicine

-  Ionizers

Common Myths About Asthma
Myth #1:
 Asthma is a psychological disease

One of the biggest beliefs that many people have is that asthma is psychological and thus they don’t believe in getting medical help. Since asthma affects the airways it is to be noted that is not psychological as it causes the immune system and the lungs to behave erratically when it comes to certain triggers.

Myth #2: Asthma medications lose their effectiveness over time

Asthma meds don’t lose their effectiveness over time and can be used for long-term if the right doses are taken as directed.

Myth #3: People with asthma should avoid physical activity

Although strenuous exercises can sometimes induce asthma, simple exercises can keep a person fit and healthy and help them lead a normal life.

Myth #4: You can outgrow asthma

Some asthma symptoms may improve over time. People also learn how to deal with asthma better as they age since they know what triggers it and what doesn’t. However, there is no outgrowing asthma because it is a lifelong condition.

Myth #5: Asthma Is Easy to Control

Asthma can be easy or difficult to control depends on the kind of asthma a person is suffering from and the triggers. Although even in mild form of asthma, the treatment is required to give the necessary relief to a person to reduce flares and maintain proper lung functions.

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Table of Content
About Bolstran 150mg Injection
When is Bolstran 150mg Injection prescribed?
What are the side effects of Bolstran 150mg Injection ?
Key highlights of Bolstran 150mg Injection
What are the substitutes for Bolstran 150mg Injection ?
How does medicine works?