Atenex 25 MG Tablet
Atenex 25 MG Tablet is primarily prescribed for the treatment of hypertension, alone or in combination with other agents; management of angina pectoris, postmyocardial infarction patients.
Atenex 25 MG Tablet is known to be a beta blocker, that is, the drug slows down the effect of some chemical that occur naturally in the body. The drug lowers blood pressure as well as heart rate causing less strain on the muscle. It is generally prescribed to those patients suffering from hypertension (high blood pressure) and angina (chest pain).
The medicine should be taken as per the dosage on the prescription. Over dosage of the drug can lead to complications. Depending on the affects the drug has on a patient, the doctor may make variations to the dosage. Doctors generally advise that this drug should not be discontinued suddenly as it can further worsen the side effects of the drug.
Take exactly as directed. Do not increase, decrease, or adjust dosage without consulting prescriber. Take pulse daily, prior to medication and follow prescriber's instruction about holding medication. Do not take with antacids.
Do not use alcohol or OTC medications (eg, cold remedies) without consulting prescriber. If diabetic, monitor serum sugars closely (may alter glucose tolerance or mask signs of hypoglycemia).May cause fatigue, dizziness, or postural hypotension; use caution when changing position from lying or sitting to standing, when driving, or when climbing stairs until response to medication is known. May cause alteration in sexual performance (reversible).
Report unresolved swelling of extremities, difficulty breathing or new cough, unresolved fatigue, unusual weight gain, unresolved constipation, or unusual muscle weakness.
This drug is used to treat the following:
How long is the duration of effect?This medicine is excreted in urine and feces. The effect lasts for a duration of 12 to 24 hours.
What is the onset of action?The peak effect of this medicine can be observed in 2 to 4 hours.
Are there any pregnancy warnings?Women who are pregnant must consult doctor before using this drug.
Is it habit forming?No habit forming tendencies were reported.
Are there any breast-feeding warnings?This medicine is not recommended for breastfeeding women. Use only if clearly needed under the doctor's supervision. Monitoring of blood pressure and blood glucose levels is necessary.
Does this affect kidney function?Dosing interval for oral atenolol in renal impairment:
- Clcr 15-35 mL/minute: Administer 50 mg/day maximum.
- Clcr <15 mL/minute: Administer 50 mg every other day maximum.
- Hemodialysis: Moderately dialyzable (20% to 50%) via hemodialysis; administer dose postdialysis or administer 25-50 mg supplemental dose.
- Peritoneal dialysis: Elimination is not enhanced; supplemental dose is not necessary.
Does this affect liver function?Caution must be taken in patients with liver disease. Adjustment of dose might be needed. Kindly consult your doctor before taking it.
Is It safe with alcohol?Caution must be taken drinking while taking Atenex 25 MG Tablet to avoid consequences.
Is it safe to drive while on this medicine?This medicine might affect the consciousness of the patient, and cause side effects like blurred vision or dizziness. Patient must avoid driving if experience any of these side effects.
Below is the list of medicines, which have the same composition, strength and form as Atenex 25 MG Tablet , and hence can be used as its substitute.
Are there any missed dose instructions?If you miss a dose of this drug, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Are there any overdose instructions?Seek emergency medical treatment or contact the doctor in case of an overdose.
This drug blocks beta receptors sites in the heart, blood vessels, and lungs. It results in inhibition of epinephrine resulting in relaxed blood vessels, thus the pressure is lowered and blood flow to the heart is improved.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Alcohol
Interaction with Lab Test
Interaction with Medicine
- Alpha-blockers (prazosin, terazosin): Concurrent use of beta-blockers may increase risk of orthostasis.
- Ampicillin, in single doses of 1 gram, decrease atenolol's pharmacologic actions.
- Antacids (magnesium-aluminum, calcium antacids or salts) may reduce the bioavailability of atenolol.
- Clonidine: Hypertensive crisis after or during withdrawal of either agent.
- Drugs which slow AV conduction (digoxin): Effects may be additive with beta-blockers.
- Glucagon: Atenolol may blunt the hyperglycemic action of glucagon.
- Insulin and oral hypoglycemics: Atenolol masks the tachycardia that usually accompanies hypoglycemia.
- NSAIDs (ibuprofen, indomethacin, naproxen, piroxicam) may reduce the antihypertensive effects of beta-blockers.
- Salicylates may reduce the antihypertensive effects of beta-blockers.
- Sulfonylureas: Beta-blockers may alter response to hypoglycemic agents.
- Verapamil or diltiazem may have synergistic or additive pharmacological effects when taken concurrently with beta-blockers.
Interaction with Food
Interaction with Disease
- Administer cautiously in compensated heart failure and monitor for a worsening of the condition (efficacy of atenolol in heart failure has not been established).
- Avoid abrupt discontinuation in patients with a history of CAD; slowly wean while monitoring for signs and symptoms of ischemia.
- Use caution with concurrent use of beta-blockers and either verapamil or diltiazem; bradycardia or heart block can occur. Avoid concurrent I.V. use of both agents.
- Beta-blockers should be avoided in patients with bronchospastic disease and peripheral vascular disease (may aggravate arterial insufficiency). Atenolol, with B1 selectivity, has been used cautiously in bronchospastic disease with close monitoring.
- Use cautiously in diabetics - may mask hypoglycemic symptoms. May mask signs of thyrotoxicosis.
- May cause fetal harm when administered in pregnancy. Use cautiously in the renally impaired (dosage adjustment required). Use care with anesthetic agents which decrease myocardial function.
- Caution in myasthenia gravis.
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