Xenadom 250 Mg/10 Mg Tablet

Xenadom 250 Mg/10 Mg Tablet is a combination medication, primarily prescribed for the treatment and prevention of migraine attack. This medication is comprized of two drugs, Naproxen and Domperidone, which belongs to the class of a non-steroidal anti-inflammatory drugs and dopamine antagonists, respectively.

On using this medicine some side effects like stomach upset, nausea, vomiting, heartburn, drowsiness, headache may occur. Serious side effects may include easy bruising or bleeding, painful swallowing, ringing in the ears, signs of kidney problems, mood changes, unusual tiredness, swelling of the ankles, feet and hands, unexplained stiff neck, unexplained weight gain and vision changes.

To ensure this medicine is safe for you tell your doctor if you have asthma, blood disorders, nasal polyps, liver disease, heart disease, stroke, high blood pressure or throat, stomach or intestinal problems.

Take this medicine by mouth as instructed by your doctor, usually 2 or 3 times in a day. Remember to not lie down for a minimum of 10 minutes after taking it. To prevent stomach upset, take this drug with milk, food or an antacid.

To reduce your risk of side effects, start the medication at the lowest effective dose for a short period of time. Take a higher dosage if needed, after consulting with a doctor.

• Migraine

• Prevention Of Migraine Attacks

• Tumor Of Pituitary Gland

• Heart Diseases

• Allergy

• Dry Mouth

• Headache

• Flu-Like Symptoms

• Indigestion

• Is It safe with alcohol?

  Use of this medication with alcohol is known to cause excessive drowsiness and calmness.

• Are there any pregnancy warnings?

  It should be avoided by pregnant women unless suggested by the doctor. The effect of this medicine on fetus is not clearly established and hence, doctor consultation is recommended before consumption.

• Are there any breast-feeding warnings?

  This medication should not be used during breastfeeding. Please consult your doctor.

• Is it safe to drive while on this medicine?

  Do not drive, operate machinery.

• Does this affect kidney function?

  Caution should be used in patients with severe renal impairment.

• Does this affect liver function?

  There is no interaction between liver impairment and consuming this drug. So dose alteration is not needed.

Below is the list of medicines, which have the same composition, strength and form as Xenadom 250 Mg/10 Mg Tablet , and hence can be used as its substitute.

• Minado Tablet

  Tas Med India Pvt Ltd

• Macprox Dp 250 Tablet

  Macleods Pharmaceuticals Pvt Ltd

• Napra D 250mg Tablet

  Intas Pharmaceuticals Ltd

• Comig 250 Tablet

  Seagull Labs (I) Pvt Ltd

• Pacinac NP 250mg/10mg Tablet

  Gentech Healthcare Pvt Ltd

• Naprodom 250Mg Tablet

  Crescent Therapeutics Ltd

• Are there any missed dose instructions?

  Missed dose should be taken as soon as possible. It is recommended to skip your missed dose, if it is the time for your next scheduled dose.

• Are there any overdose instructions?

  Consult your doctor in case of overdose.

This medication is a combination of Naproxen and Domperidone. This medicine is prescribed for the treatment of migraine attacks. As both the drugs belong to two different classes, namely, NSAIDs (Non-Steroidal Anti Inflammatory Drug) and Dopamine antagonist, respectively, thus it works via dual mechanism.

Firstly it inhibits prostaglandin synthesis by non selectively impeding the COX -1 and COX -2 enzymes. This helps in alleviating inflammation, as prostaglandin is a regulator for inflammation in muscles. Secondly, it gets attached to the dopaminergic receptors without causing any release of the chemical dopamine. This, in turn, eases gastric emptying and abate small bowel transit time.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Medicine

  Medicine

  This medication interacts with cisapride, erythromycin, ketoconazole, ramipril, tramadol, warfarin and ketorolac.

• Interaction with Disease

  Disease

  This medication should be avoided by those who suffer from kidney disease, heart disease, liver disease and asthma.

• Ques : What is Xenadom 250 Mg/10 Mg Tablet?

  Ans : Xenadom tablet is a medication which has Naproxen and Domperidone as active ingredients present in it. This medicine performs its action by obstructing the release of cyclooxygenase (chemical messengers) in the brain.

• Ques : What are the uses of Xenadom 250 Mg/10 Mg Tablet?

  Ans : Xenadom 250 mg 10 mg is used used to treat migraine and prevention of migraine attacks.

• Ques : What are the Side Effects of Xenadom 250 Mg/10 Mg Tablet?

  Ans : Flu, indigestion, mouth dryness, constipation, nausea, and liver dysfunction are possible side effects.

• Ques : What are the instructions for storage and disposal Xenadom 250 Mg/10 Mg Tablet?

  Ans : Xenadom should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Naproxen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 1 February 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/naproxen

• Naproxen- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 1 February 2020]. Available from:

  https://www.drugbank.ca/drugs/DB00788

• Domperidone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 1 February 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/domperidone

• Domperidone- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 1 February 2020]. Available from:

  https://www.drugbank.ca/drugs/DB01184