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Overview

Isoniazid

Prescription vs OTC : Prescription by Doctor required

About Isoniazid

Isoniazid is an antibacterial drug which kills tuberculosis causing organisms. It is therefore used for the treatment and prevention of tuberculosis. It is supposed to be used with other medicines till it increase its effectiveness.

Avoid using this medicine if you are allergic to it, if you have any liver disorders or if you have had hepatitis from any medicine. Tell your doctor if you have diabetes, a history of alcohol or other substance abuse, kidney problems, nerve problems, unsanitary injectable drug habits, HIV, a history of liver problems or if you are older than 35 years old, you have recently given birth, or you have previously taken isoniazid.

Common side effects include increased blood levels of liver enzymes and numbness in the hands and feet. Serious side effects may include liver inflammation. Ask your doctor if use during pregnancy is safe for the baby. Its use during breastfeeding is likely to be okay.

Isoniazid is administered into the body by mouth or by intramuscular or intravenous injections by a healthcare professional. This medicine should be taken 1 or 2 hours before meals. The dosage is based on your medical condition, age and how you respond to the first dose of the medicine.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the uses of Isoniazid

    • Tuberculosis

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the side effects of Isoniazid ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    Key highlights of Isoniazid

    • Is It safe with alcohol?

      Isoniazid 300mg tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).

    • Are there any pregnancy warnings?

      Isoniazid 300mg tablet may be unsafe to use during pregnancy.
      Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

    • Are there any breast-feeding warnings?

      Isoniazid 300mg tablet is probably safe to use during breastfeeding. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      Caution is advised when driving or operating machinery.

    • Does this affect kidney function?

      There is no interaction between renal impairment and consuming this drug. So dose alteration is not needed.

    • Does this affect liver function?

      There is no data available. Please consult doctor before consuming the drug.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of Isoniazid, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    Medicines containing Isoniazid

    Below is the list of medicines, which contains Isoniazid as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    How does this medication work?

    The active constituent of this medication is an inactive compound which is known as a prodrug. It needs to be activated by the catalase of bacteria. Once the active constituent (Isoniazid) gets activated it brings about inhibition of the synthesis of mycolic acids.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

      What are the interactions of Isoniazid ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Medicine

        Mezolam 7.5Mg Injection

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        Medzol 1Mg Injection

        null

        null

        null

        Anxil 25Mg Tablet

        null

      References

      • Isoniazid-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 9 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/isoniazid

      • Isoniazid-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 9 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00951

      • ISONIAZID tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 9 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=ISONIAZID

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Content Details
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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