Doran-O Tablet

Doran-O Tablet is primarily prescribed to the patient suffering from symptoms like indigestion, irritation, stomach pain or heartburn. It works by reducing acid production in the stomach.

It is also used as short-term (4-8 weeks) treatment of severe erosive esophagitis (grade 2 or above), diagnosed by endoscopy and short-term treatment of symptomatic gastroesophageal reflux disease (GERD) poorly responsive to customary medical treatment

This medication belongs to the antiemetics drug group. It is used for treating nausea as well as vomiting, caused by other medical treatments such as surgery, chemotherapy and radiation. This medication will block the chemical serotonin from releasing in your gut and your central nervous system. It will prevent vomiting and nausea.

You can take it with food or without food. This medication can be used alone as well as in a combination with other medicines for preventing vomiting and nausea that one experiences after a surgery, chemotherapy or radiation session.

The side effects of this tablet include dizziness, drowsiness, diarrhea, constipation and headache. These side effects are usually mild and go away in a few days or 1-2 weeks. You can consult your doctor if these symptoms remain for a long time. There are some serious side effects that this medication may have, which would require immediate medical supervision. They include:

• Stiffness of the muscle / muscle spasms
• Blurred vision or loss of vision temporarily
• Fast heartbeat and sweating
• Headache, accompanied with chest pain and a feeling of dizziness
• Yellowing of the eyes or the skin
• Hallucinating

• Nausea Or Vomiting

• Nausea

• Allergy

• Apomorphine

• Constipation

• Fatigue

• Fever

• Dry Mouth

• Anxiety

• Skin Rash

• Flatulence

• Headache

• Flushing Of Skin

• Stomach Pain

• How long is the duration of effect?

  This medication is excreted primarily in urine and the effect of this medication lasts for a duration of 12 to 28 hours.

• What is the onset of action?

  The peak effect of Doran-O Tablet can be observed within 30 minutes for Intravenous and 2 hours for the tablet.

• Are there any pregnancy warnings?

  Use of this medication is not recommended in pregnant women.

• Is it habit forming?

  No habit forming tendency has been reported.

• Are there any breast-feeding warnings?

  No clear data is available whether this medication is excreted through human breast milk. So, the use of this drug is not recommended in breastfeeding women.

• Is It safe with alcohol?

  It is advised to take caution while consuming alcohol with this medicine. Kindly consult your doctor before taking it.

• Is it safe to drive while on this medicine?

  It is found to be unsafe to drive while taking this medication, as this medicine affects the alertness of the patient.

• Does this affect kidney function?

  It is found to be safe to be used in patients with kidney disease. Adjustment of dose is not required.

• Does this affect liver function?

  Caution must be taken while using this medicine in patient with liver disease. Adjustment of dose might be required. Kindly consult your doctor before taking this medicine.

• Are there any overdose instructions?

  Seek emergency medical attention or contact the doctor in case of overdose.

• Are there any missed dose instructions?

  Missed dose should be taken as soon as possible. It is recommended to skip your missed dose, if it is the time for your next scheduled dose.

This medication works by blocking 5-HT3 receptors peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone. Also, it binds to H+/K+-exchanging ATPase in gastric parietal cells, resulting in blockage of acid secretion.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Lab Test

  Information not available.

• Interaction with Medicine

  Apomorphine

  Use of this medication with Apomorphine is not recommended. Replacement of the drug should be considered under the doctor's supervision. Usage of other medicines should be reported to the doctor.

  Amiodarone

  Use of this medication with Amiodarone is not recommended as it may cause dizziness, lightheadedness, difficulty in breathing if these drugs are used together. Regular cardiac function tests are to be performed if the patient is having any heart disease. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Usage of other medicines should be reported to the doctor.

  Amitriptyline

  If these drugs are used together, the patient may experience confusion, hallucination, changes in blood pressure, fever or excessive sweating. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Usage of other medicines should be reported to the doctor.

  Carbamazepine

  Patient's nausea and vomiting may not subside if these drugs are taken together. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Details of other drugs should be reported to the doctor.

  Phenytoin

  Patient's nausea and vomiting may not subside if these drugs are taken together. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Details of other drugs should be reported to the doctor.

  Cyclophosphamide

  The desired effect of cyclophosphamide will not be obtained if these drugs are concurrently taken. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Details of other drugs should be reported to the doctor.

• Interaction with Disease

  Qt Prolongation

  Details of any heart disease, family history of an arrhythmia or any other drugs that cause QT interval prolongation (eg: Antipsychotics, Arrhythmia drugs) should be reported to the doctor. Regular cardiac function tests are to be performed if the patient is having any heart disease.

  Liver Disease

  Details of any liver disease (jaundice, hepatitis) or other drugs that may affect the liver (eg: TB drugs, HIV drugs) should be reported to the doctor. Regular liver function tests are to be performed if the patient is having any liver disease.

• Interaction with Food

  Information not available.

• Ques : What is Doran-O Tablet?

  Ans : This medication has ondansetron and omeprazole as active ingredients present. It performs its action by obstructing the release of protein histamines. Doran o is also used to avoid gastric ulcers, esophagus inflammation and vomiting.

• Ques : What are the uses of Doran-O Tablet?

  Ans : This medication is used for the treatment and prevention from conditions and symptoms of diseases like benign duodenal ulcer, nausea acid peptic diseases. Besides these, it can also be used to treat conditions like gastric ulcers, esophagus inflammation, and vomiting.

• Ques : What are the Side Effects of Doran-O Tablet?

  Ans : This medication has some commonly reported side effects. These include headache, diarrhea, chest pain, skin rashes and dizziness. Other side effects of this medication are low blood pressure, increase in serum creatinine and swollen lips.

• Ques : What are the instructions for storage and disposal Doran-O Tablet?

  Ans : This medication should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets. A doctor should be consulted regarding the dosage of doran o.

• Ques : Should I use Doran-O Tablet empty stomach, before food or after food?

  Ans : This medication is advised to be consumed orally. The salts involved in this medication, work properly on an empty stomach. It is advised to consume this medication, 1 hour before having food and at least 2 hours after having food. Taking it with food may upset your stomach. Please consult the doctor before use.

• Ques : How long do I need to use Doran-O Tablet before I see improvement of my conditions?

  Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 1 day to 3 months, before noticing an improvement in the condition. But the same duration is not mandatory for everyone and so, it is not a standard time period for this medication's action. Please consult your doctor, for the time period you need to use this medication.

• Ques : Is there any food or drink I need to avoid?

  Ans : The diet should be normal, there is nothing as such to avoid. However, eating healthy, doing physical exercises and avoiding any kind of harmful practice like smoking or drinking can uplift your health.

• Ques : Will Doran-O Tablet be more effective if taken in more than recommended dose?

  Ans : There is no need to take this medication more than its recommended doses. Taking overdosage of this medication may trigger side effects. If the severity of the condition is not reducing with the recommended doses, then consult your doctor for re-examining your condition.