The most common causes of female infertility include - problems with ovulation, damage to fallopian tubes or uterus, or problems with the cervix. Age can contribute to infertility because as a woman ages, her fertility naturally tends to decrease. A hormone imbalance. A tumor or cyst. Eating disorders such as anorexia or bulimia. Alcohol or drug use. Thyroid gland problems. Excess weight. Stress. Intense exercise that causes a significant loss of body fat. Extremely brief menstrual cycles.