Diagnosed as Moderate Obstructive Sleep Apnoea. Hello, From last 11 years I have been suffering with Morning drowsiness, Fatigue & day time sleepiness for 15 days per month where I work more (mental and physically). From last 1 year, I thought to fight against it as I am unable to do my daily routines with this problem and hence I consulted NIMHANS, Bangalore and they came to conclusion that Depression and started T. Venlafaxine 225mg. I undergone sleep study (polysomnography) and finally it came as Moderate Obstructive Sleep Apnoea. Respiratory Distress Index is 28/hr. The doctor said that brain is awakening many times though you are not waking at night due to which I am unable to relax fully and hence the fatigue and day time sleepiness. Does this Sleep apnoea can show as more fatigability, drowsy, morning sleepy when I do more work? Whats the relation between more work and next day drowsy if I have daily sleep apnea, does the body need more rest during more work and hence the problem is being faced at heavy mental work? why this problem cant be neurasthenia as that also occurs at when more mental & physical work is done? The doctors saying that I need to go for CPAP titration and then to CPAP machine. Over internet I read that oral based appliance is also being used for Sleep apnea, which one is best, user friendly and cost effective? Can I be fully normal after using CPAP machine as I being diagnosed as psychiatric until now?