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Overview

Zinderm Iso 20 MG Capsule

Zinderm Iso 20 MG Capsule

Manufacturer: Wockhardt Ltd
Medicine composition: Isotretinoin
Prescription vs.OTC: Prescription by Doctor required

Zinderm Iso 20 MG Capsule belongs to a category of chemical compounds called retinoid. This medication helps in the treatment of cystic acne or nodular acne that has previously not responded to any other kinds of treatment. It lowers the production of facial oil and prevents hardening of the skin. If acne is not properly treated it can cause permanent scarring.

On using Zinderm Iso 20 MG Capsule you may experience the following side effects: drying of skin around the lips and mouth, bleeding from the nose, stomach upset, hair loss. Should these reactions continue or worsen with time notify your health care provider right away. However, it is advised that before taking Zinderm Iso 20 MG Capsule you should take preventive measures and consult your doctor if:

  • You are taking any prescriptive or over the counter drugs, vitamins, herbal or dietary supplements.
  • You are allergic to the ingredients contained within this drug or are allergic to any other medicines especially drugs containing vitamin A.
  • You are allergic to foods, particularly peanuts or soy.
  • You have a medical or family history of diabetes, liver disease, eating disorders, mental disorders or lowered bone density.
  • You are pregnant, are planning to become pregnant or are breastfeeding.
  • You have hearing problems, bowel problems or irregular periods.

Some medications may interact with Zinderm Iso 20 MG Capsule and have some adverse effects, in such cases care should be taken to have a discussion with your doctor. Take Zinderm Iso 20 MG Capsule as prescribed. Zinderm Iso 20 MG Capsule comes in a capsule form and needs to be swallowed down with a glass of water. You may have it with our without food. It needs to be taken twice daily for a minimum of four to five months. In case of a missed dose try to take it as soon as you recall it or skip it entirely. Do not by any means try to have a double dose. In case of drug overdose notify your doctor promptly. It may take a few weeks before results start to show.

Acne vulgaris
This medicine is used for the prevention and treatment of severe and painful nodular acne.
This medicine is not recommended for use if you have a known history of allergy to tretinoin/isotretinoin/retinoids or any other component present in the dosage form.
This medicine is not recommended for use if you have an impairment of liver function.
Hypervitaminosis A
This medicine is not recommended for use if you have more than normal levels of vitamin A in the body.
In addition to its intended effect, Zinderm Iso 20 MG Capsule may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Bone and joint pain Major Rare
Bleeding from nose Major Rare
Scaling, burning, redness, and swelling of skin Moderate Less Common
Nausea and Vomiting Moderate Rare
Stomach pain Moderate Rare
Diarrhea Moderate Rare
Pain and tenderness of eyes Moderate Rare
Itchy and dry skin Minor Less Common
Heart burn Minor Common
Rectal bleeding Moderate Rare
Difficult or painful urination Moderate Less Common
Increased thirst Minor Less Common
Increased heartbeat Moderate Rare
Ringing or buzzing in the ears Moderate Less Common
How long is the duration of effect?
The time duration for which this medicine remains effective is not clinically established.
What is the onset of action?
The effect of this medicine can be observed within 2-4 weeks of topical application.
Are there any pregnancy warnings?
Use of this medicine by women are pregnant or suspecting a pregnancy is not recommended. It is advised to take extra precautionary measures and avoid intended/unintended pregnancy while using this medicine.
Is it habit forming?
No habit forming tendencies were reported.
Are there any breast-feeding warnings?
Use of this medicine by women who are breastfeeding is not recommended. Your doctor may prescribe suitable alternatives after assessing your condition.
Below is the list of medicines, which have the same composition, strength and form as Zinderm Iso 20 MG Capsule, and hence can be used as its substitute.
Ajanta Pharma Ltd
Glenmark Pharmaceuticals Ltd
Micro Labs Ltd
Ranbaxy Laboratories Ltd
Missed Dose instructions
Skip the missed dose and continue with the regularly scheduled dose. Do not take extra medicine to make up for the missed dose.
Overdose instructions
Contact a doctor immediately if an overdose with this medicine is suspected. Symptoms of overdose may include a headache, dizziness, vomiting, stomach pain, tingling and stinging sensation of the skin etc.
India
United States
Japan
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Disease
Increased pressure around the brain Major
This medicine is not recommended for use in patients having an increased pressure around the brain due to a disease or trauma. Your doctor may determine the best course of treatment in such cases.
Psychiatric disorders Moderate
Use of this medicine may worsen the symptoms of psychiatric disorders. It should be used with caution by patients suffering from mood changes, anxiety, agitation, depression etc.
Osteoporosis Minor
Use of this medicine may cause a reduction in bone density and hence should be used with caution in patients suffering from osteoporosis or other disorders affecting bone density.
Interaction with Alcohol
Alcohol
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Lab Test
Lab
Information not available.
Interaction with Food
Food
Information not available.
Interaction with Medicine
Tetracycline Major
The oral form of isotretinoin should not be used with tetracycline or other antibiotics belonging to the same category. Your doctor will determine the best course of treatment in such cases.
Ethinyl Estradiol Major
The oral form of isotretinoin should not be used with Ethinyl estradiol or other hormonal preparations belonging to the same category. Your doctor will determine the best course of treatment in such cases. It is advised to take extra precautionary measures to avoid unintended pregnancies while using this medicine.
Natural Micronised Progesterone Major
The oral form of isotretinoin should not be used with progesterone or other hormonal preparations belonging to the same category. Your doctor will determine the best course of treatment in such cases.

Popular Questions & Answers

Can we take tretin -iso 20 mg tablet with periods postpone tablet, is there any side effects to take both together.

MBBS
General Physician, Mumbai
Can we take tretin -iso 20 mg tablet with periods postpone tablet, is there any side effects to take both together.
It’s better to avoid period postponing tablet with tretiniso tablet because of risk for suppression of bone marrow activity

I am 19 years old and I have lots of pimples on my face and body too so what should I do to get rid of them. Now even due to that my skin tone even changed.

MBBS, PGDS, DCD
Dermatologist, Srinagar
I am 19 years old and I have lots of pimples on my face and body too so what should I do to get rid of them. Now even...
You just take minoz Er 45 for 20 days and apply clin 3 cream and take bath with acne guard soap. Avoid oiling on hair.

I am 52 years old had menopause 4 years back I have lot of abdominal discomfort I.e pain ,feeling heat and burning ,I got my USG done it shows Multiple nabothian cyst at cervix, thickened endometrium ,intramural fibroid, mildly bulky uterus please advice.

MS - Obstetrics and Gynaecology
Gynaecologist, Delhi
I am 52 years old had menopause 4 years back I have lot of abdominal discomfort I.e pain ,feeling heat and burning ,I...
As even 4 years after menopause you are having thickened endometrium ,you should go for endometrial biopsy. Heat and burning are menopausal symptoms you can take cap menopace ISO daily for it.
1 person found this helpful

Mere sperm count kam h 8 ml h Kya krun mai Mujhe iso Increase krna hai kuch suggest kare please.

Bachelor of Ayurveda, Medicine and Surgery (BAMS)
Ayurveda, Chandigarh
Mere sperm count kam h 8 ml h
Kya krun mai Mujhe iso Increase krna hai kuch suggest kare please.
Take good diet Exercise Daily Eat fresh food Have black gram dal with cow ghee tadka twice a week. If you want to know more or any medicinal treatment then consult me. Have a Good Luck.

Popular Health Tips

Health Benefits of Cucumber

M.sc - Nutrition Science
Dietitian/Nutritionist, Delhi
Health Benefits of Cucumber

Cucumbers are scientifically known as Cucumis sativus and belong to the same botanical family as melons. Cucumbers have not received as much press as other vegetables in terms of health benefits, but this widely cultivated food provides us with a unique combination of nutrients. At the top of the phytonutrient list for cucumbers are its cucurbitacins, lignans, and flavonoids. These three types of phytonutrients found in cucumbers provide us with valuable antioxidant, anti-inflammatory, and anti-cancer benefits.

Health Benefits of Cucumber

1. Protect Your Brain
Cucumbers contain an anti-inflammatory flavonol called fisetin that appears to play an important role in brain health. In addition to improving your memory and protecting your nerve cells from age-related decline, fisetin has been found to prevent progressive memory and learning impairments in mice with Alzheimer's disease.

2. Reduce Your Risk of Cancer
Cucumbers contain polyphenols called lignans (pinoresinol, lariciresinol, and Seco iso lariciresinol), which may help to lower your risk of breast, uterine, ovarian, and prostate cancers. They also contain phytonutrients called cucurbitacins, which also have anti-cancer properties.

3. Fight Inflammation
Cucumbers may help to 'cool' the inflammatory response in your body.

4. Antioxidant Properties
Cucumbers contain numerous antioxidants, including the well-known vitamin C and beta-carotene. They also contain antioxidant flavonoids, such as quercetin, apigenin, luteolin, and kaempferol, which provide additional benefits.

5. Freshen Your Breath
Placing a cucumber slice on the roof of your mouth may help to rid your mouth of odor-causing bacteria.

6. Manage Stress
Cucumbers contain multiple B vitamins, including vitamin B1, vitamin B5, and vitamin B7 (biotin). B vitamins are known to help ease feelings of anxiety and buffer some of the damaging effects of stress.

7. Support Your Digestive Health
Cucumbers are rich in two of the most basic elements needed for healthy digestion: water and fiber. If you struggle with acid reflux, you should know that drinking water can help suppress acute symptoms of acid reflux by temporarily raising stomach pH; it's possible that water-rich cucumbers may have a similar effect.
Cucumber skins contain insoluble fiber, which helps add bulk to your stool. This helps food to move through your digestive tract more quickly for healthy elimination.

8. Maintain a Healthy Weight
Cucumbers are very low in calories, yet they make a filling snack (one cup of sliced cucumber contains just 16 calories)

9. Support Heart Health
Cucumbers contain potassium, which is associated with lower blood pressure levels. A proper balance of potassium both inside and outside your cells is crucial for your body to function properly.

5 people found this helpful

Keratosis Pilaris - Available Treatment For It!

MBBS, DDV, Aesthetic medicine
Dermatologist, Delhi
Keratosis Pilaris - Available Treatment For It!

If any grown-up skin faces it, it is a condition which is regarded as undiagnosed till date by dermatologists, it is none other than Keratosis Pilaris. The building of keratin on the skin and blockage of hair follicles is termed as Keratosis Pilaris. Arms, butt, and legs are the areas where the formation of these scaly plugs is likely to be found. Though not dangerous, this kind of skin texture can offer a feeling of irritation. Estimation shows that almost forty percent of adults have a tendency of having Keratosis Pilaris.

Dry weather and eczema are conditions with which Keratosis Pilaris can be closely associated. As a matter of fact, this condition also does come along with genetic conditions. Hence, the next time you have ingrown hairs, consult a doctor before you begin to scour your skin.

Areas of the skin that are affected

  1. When feeling troubles due to some irritation on your skin, especially around your legs and arms, stop for a minute and think what it can be.
  2. Allergy on your skin, white bumps similar to whiteheads, raised lumps are some the visuals that you can see on your skin if you detect that you might have Keratosis Pilaris.
  3. Patches of rough or uneven skin are also few of the symptoms.
  4. Self-diagnosing is never recommended for which you need to see a dermatologist straight away so that you do not have to think for solutions for a condition that you do not have.

Available treatments
To be honest, Keratosis Pilaris is that condition that will linger if you are an adult for life. But for a child, the effects are less harmful as the skin disease seems to fade away by the time they reach thirty. Effectual treatment options have now materialized in this modern era due to such encroachment in medical science for treating the condition of Keratosis Pilaris in the best possible way. Few medical treatments available are as follows:

  1. Laser Treatment: Reduction of inflammation, scarring and redness, call for the implementation of laser treatment. If you have acute Keratosis Pilaris, then this is the option that you must opt for.
  2. Creams: Chances are when you visit a reputed dermatologist; the expert will recommend you to apply creams that include salicylic and alpha-hydroxy acid that obstructs the building of keratin scaly plug. The amlactic body lotion is one of the products that are highly sought-after ones that also make your skin smooth and soft.
  3. Topical Immunomodulators: Tacrolimus and pimecrolimus are few topical immunomodulators that can be utilised for treating Keratosis Pilaris.
  4. Oral medication: Isotretinoin pills are considered as a very effective oral medication for this skin condition. Acne scarring can be reduced to large extents with this.

Every individual is known to have different kinds of skin. Hence, not every tip will help you to eradicate the disease but will do help in controlling the spreading of the skin condition. Listen to what your body is trying to say to you, agree with what your doctor recommends, and you will have beautiful skin in no time. In case you have a concern or query you can always consult an expert & get answers to your questions!

2607 people found this helpful

Acne (Pimples)- Myths And Facts

MBBS, Diploma in Venerology & Dermatology (DVD)
Dermatologist, Bhavnagar
Acne (Pimples)- Myths And Facts

What is acne?
Acne [pimples] is an inflammatory skin disease, which affects millions of people throughout the world. The eruptions usually occur on the face, but can also affect the arms, back and chest.

What causes acne?
The oil producing glands in the skin are called the sebaceous glands. The hormone testosterone acts on these glands at puberty leading to increased secretion of sebum. The dead cells, bacteria and sebum form a plug at the outlet of the pilosebaceous follicle. The plug formed on the surface of the skin appears as a black dot-the ‘ blackhead’. If the plug remains just below the skin it appears as a whitish elevation-the ‘whitehead’. Sometimes, the plugged follicle bursts or becomes inflamed leading to the formation of small or large solid bumps, pus pimples [pustules] and cavities containing a sticky fluid [cysts].

When does acne start?
Acne usually starts with comedones at puberty i. E. Between 10 and 12 years of age, when the greasiness of the skin starts. It affects both boys and girls. Severe acne leading to scarring can occur in both sexes though commoner in men. Acne often reaches its peak between 13 and 19 years of age. Later it generally starts subsiding, though it may persist until the early or mid-twenties. Sometimes acne starts or reappears in mid-thirties when hormonal influences play a major role.

Is it hereditary?
When a person suffers from severe acne it is often found that one or both of his or her parents have had it like this; however this is not always so.

Does diet influence acne?
High caloric food can trigger or exacerbate existing acne. But here I want to put the fact that a high glycemic index diet act as single edged sword but milk and milk products act as double edged sword. So if you have serious type acne then you have to give up your love for milk. And also if if you are convinced that a particular food exacerbates acne then it might be worthwhile avoding the same. Have healthy food habits and eat a lot of fresh fruits, vegetables, salads and drink a lot of water.

Do I have to avoid cosmetics if I have acne?
Greasy [oil based cosmetics] block the pores on the skin and tend to bring on or increase preexisting acne. The same applies to moisturizers that are too heavy and may block the skin pores. A sudden bout of acne following facials, clean-up, bleaching ect…is common.

Can drugs cause acne?

Pills [oral contraceptives] can sometimes aggravate acne. Steroids, inh [given for tuberculosis] and anti-epileptics like phenobarbitone can produce acne. Topical steroids applied on the face often triggers acneform eruptions after they are withdrawn.

Are there any other predisposing factors?
A shower of new lesions often occurs a few days prior to the onset of menstruation in females. Tight fitting jeans may occlude the ducts leading to acne on the buttocks and thighs. Prolonged wearing of helmets can lead to pimples on the forehead. Both acne and dandruff occur on greasy skin and can coexist.

Why should acne be treated at all?

Acne can produce pustules and cysts, which can lead to pemanent disfiguring scars if left, untreated. Acne can scar not only the skin but also the psyche. It can produce low self-esteem, self-consciousness, anxiety, depression and introvert personality. Clear skin helps tremendously in boosting the self-confidence of an individual.

What is the right treatment for acne?
Consult your dermatologist for a proper scientific treatment. There are some general instructions to be followed by the patients:
1) wash your face 3-4 times daily with soap and water.
2) the scalp should be cleansed 2-3 times a week preferably with shampoo.
3) avoid all greasy cosmetics on the face.
4) do not squeeze pimples. It can cause severe scarring.

There are several topical agents and oral medications available for successful treatment which your doctor will decide. You may need long courses of antibiotics for several months in severe acne. For resistant, severe recalcitrant acne your doctor may suggest a medication called isotretinoin.

But you should have a lot of patience and take medications and take medications in the correct doses prescribed and for a proper length of time. Remember that it might take several weeks for acne medication to take effect and the face to clear.

 I ignored my acne and now I have scars. Can you do something for my scars?
It is always better to prevent scars by proper and early treatment of severe acne. Your doctor will advise you on treatment available for marks.

14 people found this helpful

Acne (Pimples)- Myths and Facts

MD - Dermatology , Venereology & Leprosy, MBBS
Dermatologist, Dehradun
Acne (Pimples)- Myths and Facts

What is acne?
Acne [pimples] is an inflammatory skin disease, which affects millions of people throughout the world. The eruptions usually occur on the face, but can also affect the arms, back and chest.

What causes acne? 
The oil producing glands in the skin are called the sebaceous glands. The hormone testosterone acts on these glands at puberty leading to increased secretion of sebum. The dead cells, bacteria and sebum form a plug at the outlet of the pilosebaceous follicle. The plug formed on the surface of the skin appears as a black dot-the ‘ blackhead’. If the plug remains just below the skin it appears as a whitish elevation-the ‘whitehead’. Sometimes, the plugged follicle bursts or becomes inflamed leading to the formation of small or large solid bumps, pus pimples [pustules] and cavities containing a sticky fluid [cysts]. 

When does acne start?
Acne usually starts with comedones at puberty i. E. Between 10 and 12 years of age, when the greasiness of the skin starts. It affects both boys and girls. Severe acne leading to scarring can occur in both sexes though commoner in men. Acne often reaches its peak between 13 and 19 years of age. Later it generally starts subsiding, though it may persist until the early or mid-twenties. Sometimes acne starts or reappears in mid-thirties when hormonal influences play a major role.

Is it hereditary?
When a person suffers from severe acne it is often found that one or both of his or her parents have had it like this; however this is not always so.

Does diet influence acne?
High caloric food can trigger or exacerbate existing acne. But here I want to put the fact that a high glycemic index diet act as single edged sword but milk and milk products act as double edged sword. So if you have serious type acne then you have to give up your love for milk. And also if if you are convinced that a particular food exacerbates acne then it might be worthwhile avoding the same. Have healthy food habits and eat a lot of fresh fruits, vegetables, salads and drink a lot of water. 

Do I have to avoid cosmetics if I have acne?
 Greasy [oil based cosmetics] block the pores on the skin and tend to bring on or increase preexisting acne. The same applies to moisturizers that are too heavy and may block the skin pores. A sudden bout of acne following facials, clean-up, bleaching ect…is common.

Can drugs cause acne? 

Pills [oral contraceptives] can sometimes aggravate acne. Steroids, inh [given for tuberculosis] and anti-epileptics like phenobarbitone can produce acne. Topical steroids applied on the face often triggers acneform eruptions after they are withdrawn.

Are there any other predisposing factors?
A shower of new lesions often occurs a few days prior to the onset of menstruation in females. Tight fitting jeans may occlude the ducts leading to acne on the buttocks and thighs. Prolonged wearing of helmets can lead to pimples on the forehead. Both acne and dandruff occur on greasy skin and can coexist.

Why should acne be treated at all?

Acne can produce pustules and cysts, which can lead to pemanent disfiguring scars if left, untreated. Acne can scar not only the skin but also the psyche. It can produce low self-esteem, self-consciousness, anxiety, depression and introvert personality. Clear skin helps tremendously in boosting the self-confidence of an individual.

What is the right treatment for acne? 
Consult your dermatologist for a proper scientific treatment. There are some general instructions to be followed by the patients: 
1) wash your face 3-4 times daily with soap and water.
2) the scalp should be cleansed 2-3 times a week preferably with shampoo.
3) avoid all greasy cosmetics on the face.
4) do not squeeze pimples. It can cause severe scarring.

There are several topical agents and oral medications available for successful treatment which your doctor will decide. You may need long courses of antibiotics for several months in severe acne. For resistant, severe recalcitrant acne your doctor may suggest a medication called isotretinoin.

But you should have a lot of patience and take medications and take medications in the correct doses prescribed and for a proper length of time. Remember that it might take several weeks for acne medication to take effect and the face to clear.

 I ignored my acne and now I have scars. Can you do something for my scars? 
It is always better to prevent scars by proper and early treatment of severe acne. Your doctor will advise you on treatment available for marks

4 people found this helpful

Whiteheads - What Are They & How You Can Get Rid Of Them?

Dermatologist
Dermatologist, Delhi
Whiteheads - What Are They & How You Can Get Rid Of Them?

Similar to blackheads are whiteheads, which develop on our skin. Both blackheads and whiteheads are caused due to clogged pores. However, as opposed to blackheads, whiteheads cannot be extracted by squeezing. Whiteheads are a form of acne that is referred to as closed comedo. They appear on the skin as small round white or light-coloured bumps. When excess oil is secreted in the skin, dead skin cells clog the pore area and block the pore opening, whiteheads are formed. Unlike blackheads that keep the pore open, whiteheads, on the other hand, block the pores.

Causes of whiteheads
Clogged pores are the prime reason that causes whiteheads, and they can occur due to any of the following reasons:

  • Excessive oil secretion or sebum
  • Hormonal changes occurring due to puberty, pregnancy, and menstruation
  • Birth control pills
  • Sweating and humidity
  • Use of certain cosmetics or products that are harmful
  • Eating excessive oily or greasy foods
  • Genetic predisposition


Treatment of whiteheads
Over-the-counter (OTC) creams or prescribed medications by a dermatologist are the ideal treatments for whiteheads. Self-care and some preventive measures will also keep them at bay. OTC creams that contain salicylic acid, benzoyl peroxide, resorcinol or sulphur may be helpful. With extreme conditions, oral medications like isotretinoin, or Accutane may be prescribed, but these come with potential side effects.

Self-care tips 
Practising some of the following preventive self-care measures will prevent formation of whiteheads:
Wash your skin twice daily with lukewarm water and mild soap.

  • Don’t squeeze pimples.
  • Practice caution while shaving.
  • Avoid excessive exposure to sunlight.
  • Use oil-free skin products.
  • Remove makeup before going to bed.
  • Opt for non-comedogenic or non-pore-clogging products.
  • Wear loose-fitting clothing made of non-synthetic fabrics to let your skin breathe.
  • Wash your hair regularly.
  • Use fragrance-free water-based emollient for dry skin.
  • Continue your skincare regimen.

Here are some remedies you can try to get rid of whiteheads:

  1. Baking soda scrub: Make a homemade scrub mixing one tsp. of baking soda with enough water to make a paste. Scrub it into the problem area. Let it dry for 15-20 minutes and wash it off with lukewarm water. Baking soda is a natural exfoliant and astringent that eradicates all impurities, which clog the pores. It also balances the oil production in the skin.
  2. Tea tree oil: Dab a cotton swab with tea tree oil and apply it on the whiteheads to prevent bacterial infection.

The above are just some measures to avoid whiteheads. If the problem persists, then it's time to seek medical assistance and schedule an appointment with a dermatologist to eradicate these pesky whiteheads.

In case you have a concern or query you can always consult an expert & get answers to your questions!

4348 people found this helpful