Zempred 4 MG Tablet
Zempred 4 MG Tablet is primarily as an anti-inflammatory or immunosuppressant agent in the treatment of a variety of diseases including those of hematologic, allergic, inflammatory, neoplastic, and autoimmune origin. It is also used in the prevention and treatment of graft-versus-host disease following allogeneic bone marrow transplantation.
Zempred 4 MG Tablet is a steroid, which prevents the release of certain chemicals in the body that result in inflammation. The drug is quite effective in the treatment of a number of inflammatory health problems such as gland disorders, lupus, arthritis, psoriasis as well as ulcerative colitis.
It also treats various other inflammatory conditions of the lungs, skin, eyes, blood cells, stomach and nervous system of the body. Before you start the medicine the doctor needs to ensure:
- If the medicine is safe for the patient
- If you have allergies, overall fitness, and existing health problems
- If you have problems like hypertension, heart disease, kidney or liver issues, tuberculosis, pinworms, thyroid disorders, mental illness, epilepsy or epilepsy
The dosage of the medicine for adults may vary from 4mg to 48mg daily. In the case of children, the dosage is decided to depend upon the health of the patient and the condition that is being treated.
Certain precautions should also be taken to prevent side effects from aggravating. For instance, avoid grapefruit juice consumption. it is also advised that ‘live’ vaccines should not be taken when on this drug. Patients taking this medication can easily catch infections. Thus they should also avoid interacting with sick family members or friends.
Zempred 4 MG Tablet must be used with caution in patients with hyperthyroidism, cirrhosis, nonspecific ulcerative colitis, hypertension, osteoporosis, thromboembolic tendencies, CHF, convulsive disorders, myasthenia gravis, thrombophlebitis, peptic ulcer, diabetes.
Because of the risk of adverse effects of Zempred 4 MG Tablet, systemic corticosteroids should be used cautiously in the elderly, in the smallest possible dose, and for the shortest possible time.
Arrhythmias and cardiovascular collapse are possible with rapid intravenous infusion of high dose methylprednisolone. Symptoms of overdose include cushingoid appearance (systemic), muscle weakness (systemic), osteoporosis (systemic) all with long-term use only.
When consumed in excessive quantities for prolonged periods, systemic hypercorticism and adrenal suppression may occur; in those cases, discontinuation and withdrawal of the corticosteroid should be done judiciously.
Maintain adequate nutritional intake; consult prescriber for possibility of special dietary instructions. If diabetic, monitor serum glucose closely and notify prescriber of any changes; this medication can alter hypoglycemic requirements.
The medication can treat the below provided problems:
How long is the duration of effect?The effect of this medicine lasts for a duration of 30-36 hours after an oral dose and 1-4 weeks after an intramuscular injection.
What is the onset of action?The peak effect of this medicine is observed within 30 minutes of an intravenous injection.
Are there any pregnancy warnings?This medicine is recommended for pregnant women only if clearly needed and if no other safer alternative is available.
Is it habit forming?No habit forming tendencies were reported.
Are there any breast-feeding warnings?This medicine is known to be excreted through breast milk in small amounts.
Is It safe with alcohol?Consumption of alcohol must be avoided when you were taking Zempred 4 MG Tablet.
Is it safe to drive while on this medicine?This medicine might affect the consciousness of the patient, thus driving must be avoided.
Does this affect kidney function?This medicine is found to be safe in patient with kidney disease. Adjustment of dose is not needed.
Does this affect liver function?Limited information is available on the use of this medicine in patient with liver disease. kindly consult your doctor before taking this.
Below is the list of medicines, which have the same composition, strength and form as Zempred 4 MG Tablet , and hence can be used as its substitute.
Missed Dose instructionsThe missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for your next dose.
Overdose instructionsSeek emergency medical treatment or contact the doctor in case of an overdose.
This medicine belongs to Glucocorticoids class of drugs. It works by binding to the receptor and inhibits the release of inflammatory substances thus helps in the treatment of inflammation or allergic disorders.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Alcohol
Interaction with Lab Test
Interaction with Medicine
- CYP3A enzyme inducer.
- Phenytoin, phenobarbital, rifampin increase clearance of methylprednisolone.
- Potassium depleting diuretics enhance potassium depletion.
- Skin test antigens, immunizations decrease response and increase potential infections
- Methylprednisolone may increase circulating glucose levels and may need adjustments of insulin or oral hypoglycemics
Interaction with Diseasebleeding is more when taken for a long duration of time. Dose adjustments are to be made based on the clinical condition.
DiabetesThis medicine is used with caution in the patients with diabetes as it increases the blood glucose levels. Regular monitoring of blood glucose levels is necessary. A suitable antidiabetic agent is prescribed based on the clinical condition.
OthersUse with caution in patients with hyperthyroidism, cirrhosis, nonspecific ulcerative colitis, hypertension, osteoporosis, thromboembolic tendencies, CHF, convulsive disorders, myasthenia gravis, thrombophlebitis, peptic ulcer.
Interaction with Food
- Consumption of grapefruit juice is not recommended when you are taking Zempred 4 MG Tablet. Inform the doctor if you experience any undesired effects.
- Should be taken after meals or with food or milk; limit caffeine; need a diet rich in pyridoxine, vitamin C, vitamin D, folate, calcium, phosphorus, and protein.
Ques: What is Zempred 4 MG Tablet?
Ques: How long do I need to use Zempred 4 MG Tablet before I see improvement in my condition?
Ques: At what frequency do I need to use Zempred 4 MG Tablet?
Ques: Should I use Zempred 4 MG Tablet empty stomach, before food or after food?
Ques: What are the instructions for the storage and disposal of Zempred 4 MG Tablet?
Ques: Does Zempred 4 MG Tablet contain penicillin?
Ques: Does Zempred 4 MG Tablet expire?
Ques: Is Zempred 4 MG Tablet a pain-killer?
Ques: Is Zempred 4 MG Tablet safe?
Ques: Is Zempred 4 MG Tablet an immunosuppressant?
Ques: Is Zempred 4 MG Tablet a glucocorticoid?
Ques: Can I take Zempred 4 MG Tabletn with antibiotics?
Ques: Can I take Zempred 4 MG Tablet with paracetamol?
Methylprednisolone-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 1 June 2022].Available from:https://druginfo.nlm.nih.gov/drugportal/name/methylprednisolone
Methylprednisolone-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 1 June 2022].Available from:https://go.drugbank.com/drugs/DB00959
METHYLPREDNISOLONE Tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 1 June 2022].Available from:https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=METHYLPREDNISOLONE
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