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Rituximab

Prescription vs.OTC: Prescription by Doctor required

Rituximab acts as a monoclonal antibody. This drug is relatively new and is used to offer targeted therapy to treat cancer. Rituximab only targets cancer cells in the body, thus the drug is less harmful as compared to Rituximab radiation treatment.

Rituximab is used to treat chronic lymphocytic leukemia and some types of non-hodgkin’s lymphoma.

The first dose of Rituximab is given through an IV for about 6 hours. The time period of administering the dose may be reduced afterwards. Rituximab is not available in the form of a tablet or pill. The dosage is determined by the doctor as per the patient’s health, age, weight, severity of the cancer and the body’s reaction to the drug.

You may or may not experience any related side effects of Rituximab, such as fever accompanied with chills, nausea and vomiting, cough, headache, irritation of the throat and runny nose. If you do experience these side effects, do not be alarmed, just inform you doctor and he will provide medicine to control the symptoms.

There are a few rare but very serious side effects that can occur when you take Rituximab, such as pain in the chest, confusion and problems with breathing. Get in touch with the doctor immediately in this case and seek treatment.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Oncologist before using this medicine.

non-hodgkin lymphoma (nhl)

blood cancer (chronic lymphocytic leukemia)

In addition to its intended effect, Rituximab may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Headache

Weakness

Edema

Chills

Febrile neutropenia

Decreased white blood cell count (neutrophils)

Infusion reaction.

Is It safe with alcohol?

Interaction with alcohol is unknown. Please consult your doctor.

Are there any pregnancy warnings?

Toritz t 500mg injection may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Are there any breast-feeding warnings?

Unknown. Human and animal studies are not available. Please consult your doctor.

Is it safe to drive while on this medicine?

There is no data available. Please consult doctor before consuming the drug.

Does this affect kidney function?

There is no data available. Please consult doctor before consuming the drug.

Does this affect liver function?

There is no data available. Please consult doctor before consuming the drug.

Are there any missed dose instructions?

If you miss a dose of Rituximab, please consult your doctor.
Below is the list of medicines, which contains Rituximab as ingredient
Roche Products India Pvt Ltd
Dr Reddy s Laboratories Ltd
Torrent Pharmaceuticals Ltd
Intas Pharmaceuticals Ltd
Emcure Pharmaceuticals Ltd
Roche Products India Pvt Ltd
Intas Pharmaceuticals Ltd
Intas Pharmaceuticals Ltd
Torrent Pharmaceuticals Ltd
Intas Pharmaceuticals Ltd
Intas Pharmaceuticals Ltd
Dr Reddy s Laboratories Ltd
Dr Reddy s Laboratories Ltd
Intas Pharmaceuticals Ltd
Emcure Pharmaceuticals Ltd
Alkem Laboratories Ltd
Hetero Drugs Ltd
Hetero Drugs Ltd
Intas Pharmaceuticals Ltd
Reliance Life Sciences
Rituximab is used in the treatment of certain types of cancer and autoimmune diseases. This drug binds to the CD20 antigen that is present on the B lymphocytes, and, the Fc domain appoints antibodies to interpose cell lysis.
What are you using Rituximab for?
Other
non-hodgkin lymphoma (nhl)
Rheumatoid Arthritis
Pain
blood cancer
How much was the improvement?
Poor
Excellent
Average
How long did it take before seeing improvement?
Within 2 hours
Within 6 hours
More than 2 days
Within a day
How frequently did you take this medicine?
Once a day
Four times A Day
Not taking on daily level
Thrice a day
How did you take this medicine?
Empty stomach
With Food
With or without food
What were the side effects of this medicine?
Hair Loss
Infection
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

I have pemphigus vulgaris and I am on omnacortil medicine as of now. My condition is not improving and my doctor has asked me to go for Rituximab injections. Does these injections provide speedy recovery and hope I don't have to take it again and again, right? Can you please brief?

MBBS, MD - Dermatology, venereology & Leprology, Fellowship in Cosmetology (MUHS)
Dermatologist, Kota
I have pemphigus vulgaris and I am on omnacortil medicine as of now. My condition is not improving and my doctor has ...
Dear lybrate-user. Rituximab is a costly drug but it doesn't have side effects as those of omnacortil. Pemphigus vulgaris is not a one time disease. But we have no other option than taking medicines. I would prefer rituximab over omnacortil if affordability is not an issue.
6 people found this helpful

I am being diagnosed with pemphigus vulgaris for last 3 months now. And I have been on steroids like omnacortil for last 3 months. Can you please brief me about rituximab injections? Should I go for it?

MBBS
General Physician, Mumbai
I am being diagnosed with pemphigus vulgaris for last 3 months now. And I have been on steroids like omnacortil for l...
Pemphigus vulgaris is an auto immune disease and we can control it but not cure it fully and you are already taking omnocortil and if you are having more unwanted symptoms than rheumatologist decides whether an extra medication of rituximab needs to be given or not.
1 person found this helpful

What is wrangler granulomatosis disease? What are the symptoms and is it permanently curable?

M.D. Consultant Pathologist, CCEBDM Diabetes, PGDS Sexology USA, CCMTD Thyroid, ACDMC Heart Disease, CCMH Hypertension, ECG
Sexologist, Sri Ganganagar
What is wrangler granulomatosis disease?
What are the symptoms and is it permanently curable?
Granulomatosis with polyangiitis (GPA), formerly known as Wegener granulomatosis, is a rare multisystem autoimmune disease of unknown etiology. Its hallmark features include necrotizing granulomatous inflammation and pauci-immune vasculitis in small- and medium-sized blood vessels. Several other drugs may help decrease the function of the immune system cells causing inflammation. They include cyclophosphamide, azathioprine (Azasan, Imuran) and methotrexate (Rheumatrex, Trexall). Rituximab (Rituxan) is another option for treating granulomatosis with polyangiitis.
1 person found this helpful

Dear Sir My wife 42 years was suffering from Adrenal insufficiency from Feb 2009 along with Hypo Thyroidism .Her ANA was positive since 2009 however she was doing fine till 15th Dec 2016 and she was on Wysolone 5 and Thyrox 88 (Dosage tapered from 25-50-75--88 (recently)}in last 7 years. On.16. December 2016. Her Blood pressure got elevated to 234/ 134 and when we admitted her into Hospital .Her Creatinine was 3.4 which has gone UpTo 5.44 and with 3 shots of pulse steroids like Methyl prednisolone and one Immunosuppressant drug Cyclophosphamide it came down to 3.67 which is again increasing now and reach to 4.40 on 12th Jan 2017. Her Platelet were approx 46000 at the time of admission which dipped to 22000 and after that she was administered 3 SDP and 1 unit of blood and Platelet reached to 1.22 Lakhs. However again it came down to 19000 few days back and it was 42000 on 12th Jan 2017 Already 5 sessions of Plasmapheresis has happened Report of bone marrow biopsy is awaited. Doctors Panel (comprising of 2 nephrologist 1 Rheumatologist Hematologist) were discussing the idea of adding rituximab however she got some lung infection--they have differed the decision until infection is over. Blood Pressure is fluctuating since last one month--Systolic---(120--200) and dystolic (80--110) even after 4 drugs from last 30 days. Please advise Imp--sjogren syndrome is confirmed through APAP reports and ANA profile is strongly positive for SS-A.

PhD, Human Energy Fields, Diploma in PIP, EFI, Aura scanning for Health evaluation; Energy field assessment, Fellowship Cardiac Rehabilitation, Cardiac Rehabilitation, MD (Ayur - Mind Body Med), Mind Body Medicine
Non-Invasive Conservative Cardiac Care Specialist, Pune
Dear Sir
My wife 42 years was suffering from Adrenal insufficiency from Feb 2009 along with Hypo Thyroidism .Her ANA ...
Ideally follow doctors advice as there is relatively little information on this disorder. One tip. Natural food based Vit A and sunlight rich Vit D will help. If she can sit for 10 to 15 mibs daily in early morning sunlight and have red, orange rich vegrtables and fruits, it will help. If you can approach a Healer. Some drugless support will helpnboth of you. Regards.
2 people found this helpful

Hello, My dad is diagnosed with Acute Lymphoblastic Leukemia BCell type. Philadelphia Chromosome negative and his report expressed CD20 marker. He was treated with modified gmall protocol. I would like to know if some other protocol would be better for him. And would using Rituximab as a combination with chemotherapy would help him better with the prognosis or is Rituximab only used after relapse. Please give an advise as Its hard to find doctors treating blood disorders. Thanks and Regards

Post Doctoral Research (Ph.D.) (A.M) (Oncology), Integrative Oncology For Physicians (MSKCC, N.Y, USA), Doctor of Natural Medicine (N.D/ N.M.D), PG Diploma In Clinical Counseling, PG Diploma In Oncology & Haematology (A.M), Ayurveda (I) Certification, Clinically Relevant Herb-Drug Interactions (CME) (Cine-Med Inc. USA), Advanced Strategic Management (APSM), B.E (Computer Sc. & Engg.), Certificate Course in Homeopathic Oncology
Alternative Medicine Specialist, Bhubaneswar
Hello, My dad is diagnosed with Acute Lymphoblastic Leukemia BCell type. Philadelphia Chromosome negative and his rep...
Hi lybrate-user, I appreciate you seeking help for your father. Is your father's treatment basis the Gmall protocol, already over? As far as I understand, targeted therapy with 'Rituximab' is used (often) along with chemotherapy for better clinical outcomes. This may be used either as a part of the initial treatment or as a part of the 2nd line treatment regimen. However, the decision to go for a targeted therapy is to be taken by your father's consulting physician/ haemato-oncologist, as would deem contextually appropriate. Above-mentioned apart, you may also evaluate options of an autologous/ allogenic stem cell transplant, once remission is achieved, with your haemato-oncologist. A stem cell transplant, if feasible in your father's case, may possibly help improve disease free survival. Should it require, please proceed for a second opinion suitably here. Simultaneously, also do note that an integrative treatment with natural/ alternative medicines is likely to influence outcomes too. Hope this helps. Do take care and all the very best.
1 person found this helpful

Popular Health Tips

Uveitis - Do You Know It Can Increase The Risk Of Other Diseases?

MBBS, MS - Ophthalmology
Ophthalmologist, Ghaziabad
Uveitis - Do You Know It Can Increase The Risk Of Other Diseases?

Uveitis is a set of inflammatory diseases that results in the swelling and damaging of the eye tissue. It can lead to temporary or permanent loss of vision. This disease often affects a part of the eye called the uvea, from which it has derived its name. It can affect people of all ages and can last from a short to long period of time. Ophthalmologists categorize uveitis into four major parts posterior uveitis, anterior uveitis, panuveitis uveitis and intermediate uveitis. This disease can be infectious or noninfectious, depending on the nature of the infection.

What causes uveitis and what are the major risk factors?
This disease is caused by the eye's inflammatory response and is caused by a series of potential factors such as the following:

  • Immune system attack from the body
  • Eye bruises
  • Eye infection or tumor within the eye
  • Foreign toxins that penetrate the eye

What are the diseases associated with uveitis?
Uveitis is associated with a range of diseases such as multiple sclerosis, Behcet's syndrome, Vogt-Koyanagi-Harada's (VKH) disease, psoriasis, herpes zoster infection, tuberculosis, rheumatoid arthritis, ulcerative colitis, toxoplasmosis, and cytomegalovirus (CMV) retinitis.

What are the typical symptoms of uveitis?
One or both eyes can be affected by uveitis. Some of the common symptoms include pain in the eye, light sensitivity and blurred and dark spots in vision. Moreover, the symptoms might vary from person to person and greatly depends on the type of inflammation. The symptoms also vary according to the type of uveitis.

What is the detection process?
The process of detection starts with a patient's medical history followed by several medical tests to rule out autoimmune disorders. This is followed by an evaluation of the central nervous system to rule out multiple sclerosis. Some of the other tests conducted by ophthalmologists include measuring the ocular pressure, slit lamp exam, funduscopic exam and visual acuity test.

The primary aim of the treatment is to eradicate inflammation, restore vision, prevent tissue damage and reduce pain. The treatment plan depends on the type of uveitis a patient displays. Doctors often suggest a dose of corticosteroid eye drops to arrest the infection in and around the eye. Other treatment methods include the prescription of immunosuppressive agents.

Furthermore, a doctor may suggest steroidal medication in the form of an eye drop, pill or injection. It can also be surgically infused into the eye. Some other agents used for treatment are azathioprine, methotrexate and mycophenolate. Medications such as these require regular monitoring of the blood to check for any side effects. Doctors also suggest biologics such as infliximab, rituximab, and adalimumab. Most of these drugs have a specific target in the immune system.

In case you have a concern or query you can always consult an expert & get answers to your questions!

5044 people found this helpful

Rheumatoid Arthritis - Why It Is Important To Treat It On Time?

MD - General Medicine, DM - Rheumatology
Rheumatologist, Delhi
Rheumatoid Arthritis - Why It Is Important To Treat It On Time?

Rheumatoid arthritis is a chronic inflammatory arthritis with a prevalence of 0.5-1% in India. It is characterized by joint pain and swelling associated with morning stiffness lasting for more than 30 minutes. It generally has a slow onset - over weeks to months, though the onset can be acute also. Most common joints involved are small joints of hands and feet. Larger joints like knee and shoulder can also be involved. The incidence of RA increases with age. It is twice more common in females than in males. Early treatment is necessary to bring down the inflammation, avoid joint deformities and prevent other complications (lung, heart, vasculitis). 

CAUSE: 

Predisposition to RA is multifactorial. It has a genetic component (family history of RA increases the risk). Environmental factors like smoking also play a role. 

SYMPTOMS: 

Initial symptoms start with fatigue, malaise, generalised bodyaches, low-grade fever. The onset is generally slow and eventually patient develops joint pain and swelling. Though the joint involvement is symmetrical in most cases, asymmetric onset is common (involving joints predominantly on one side). 

DIAGNOSIS: 

Diagnosis is made by a physician after detailed history, clinical examination and supportive lab tests. Rheumatoid factor and anti-CCP antibody are positive in 75-80% patients with RA. They have raised inflammatory markers (ESR, CRP) during active inflammation. 

TREATMENT:

RA treatment options are wide and quite effective. It starts with patient education regarding nature of the disease and the risk of complications. The need of early aggressive therapy should be emphasized. The patient should put in efforts for physiotherapy which play a very important role in muscle strength and joint mobility. Pharmacotherapy options are wide and include disease-modifying antirheumatic drugs (DMARDS). These can be conventional DMARDS like methotrexate (usually the first line drug), sulfasalazine, hydroxychloroquine, leflunomide. Failure to adequately respond to these drugs should lead your Rheumatologist to consider Biologic DMARDS (TNF antagonists, Rituximab, Abatacept, Tocilizumab). Your Rheumatologist is the best person to guide you about dose, indications, monitoring and side effects of the drugs used in RA. Treatment duration depends on patient's response but is generally long (5-10 years or lifelong). 

COMPLICATIONS BEYOND JOINTS: 

RA patients can have rheumatoid nodules in skin, lungs, heart and other sites. These patients are at risk of accelerated bone loss, so calcium and vitamin D intake should be optimized. Eye complications include dryness, redness (scleritis and episcleritis) and certain eye threatening complications. Lung involvement can be seen in various forms (fluid in lungs, nodules, interstitial lung disease). 

These patients are at high risk of atherosclerosis (heart and blood vessel disease). They also have a tendency to have frequent infections. 

NEED OF THE HOUR: 

All patients with joint pains should be seen early by Rheumatologist for diagnosis and treatment. With so many treatment options, no patient should suffer from joint deformities and other complications associated with long standing, untreated RA. LEAD A HEALTHY LIFE! If you wish to discuss about any specific problem, you can consult a rheumatologist.

2595 people found this helpful

What Is Uveitis? How Can It Be Treated?

Super-Speciality Trained Ophthalmologists
Ophthalmologist, Delhi
What Is Uveitis? How Can It Be Treated?

Uveitis is a set of inflammatory diseases that results in the swelling and damaging of the eye tissue. It can lead to temporary or permanent loss of vision. This disease often affects a part of the eye called the uvea, from which it has derived its name. It can affect people of all ages and can last from a short to long period of time. Ophthalmologists categorize uveitis into four major parts posterior uveitis, anterior uveitis, panuveitis uveitis and intermediate uveitis. This disease can be infectious or noninfectious, depending on the nature of the infection.

What causes uveitis and what are the major risk factors?
This disease is caused by the eye's inflammatory response and is caused by a series of potential factors such as the following:

  • Immune system attack from the body
  • Eye bruises
  • Eye infection or tumor within the eye
  • Foreign toxins that penetrate the eye

What are the diseases associated with uveitis?
Uveitis is associated with a range of diseases such as multiple sclerosis, Behcet's syndrome, Vogt-Koyanagi-Harada's (VKH) disease, psoriasis, herpes zoster infection, tuberculosis, rheumatoid arthritis, ulcerative colitis, toxoplasmosis, and cytomegalovirus (CMV) retinitis.

What are the typical symptoms of uveitis?
One or both eyes can be affected by uveitis. Some of the common symptoms include pain in the eye, light sensitivity and blurred and dark spots in vision. Moreover, the symptoms might vary from person to person and greatly depends on the type of inflammation. The symptoms also vary according to the type of uveitis.

What is the detection process?
The process of detection starts with a patient's medical history followed by several medical tests to rule out autoimmune disorders. This is followed by an evaluation of the central nervous system to rule out multiple sclerosis. Some of the other tests conducted by ophthalmologists include measuring the ocular pressure, slit lamp exam, funduscopic exam and visual acuity test.

The primary aim of the treatment is to eradicate inflammation, restore vision, prevent tissue damage and reduce pain. The treatment plan depends on the type of uveitis a patient displays. Doctors often suggest a dose of corticosteroid eye drops to arrest the infection in and around the eye. Other treatment methods include the prescription of immunosuppressive agents.

Furthermore, a doctor may suggest steroidal medication in the form of an eye drop, pill or injection. It can also be surgically infused into the eye. Some other agents used for treatment are azathioprine, methotrexate and mycophenolate. Medications such as these require regular monitoring of the blood to check for any side effects. Doctors also suggest biologics such as infliximab, rituximab, and adalimumab. Most of these drugs have a specific target in the immune system.

4558 people found this helpful

Psoriasis Treatment

MD - Ayurveda, Ph.D Arthritic Disorder, Bachelor of Ayurveda, Medicine and Surgery (BAMS)
Ayurveda, Surat
Psoriasis Treatment

Treatment & Dosage:

  • Tablet Salin- one or two tablet two times or three times a day
  • Salin Syrup - one or two tea Spoon two times or three times a day
  • Tablet Daa - one or two tablet two times or three times a day
  • Immunosun Capsule - one or two tablet two times or three times a day
  • Nimbamrutadi Kasayam - two tea Spoon two times or three times a day with water
  • Triflanimbadi Kasayam - two tea Spoon two times or three times a day with water
  • Sunthiyadi Kasayam - two tea Spoon two times or three times a day with water
  • Manjisthadi kasayam - two tea Spoon two times or three times a day with water
  • Arogyavardgini vati - one or two tablet two times or three times a day
  • Krumina Syrup - one or two tea Spoon two times or three times a day
  • Krumina Tablet - one or two tablet two times or three times a day
  • Mansi Syrup - one or two tea Spoon two times or three times a day
  • Antress Tablet- one or two tablet two times or three times a day

In Psoriatic Arthritic Conditions: 

  • Tablet Itis
  • Tablet Healbo
  • Tablet Suvarna sallaki RA
  • Tablet Ashwasallaki RA
  • Vatari kasaym
  • Kachnar Kasayam

External Medicines

  • Dermosun Ointment – Apply on effected part / whole body twice a days
  • Salin Oil - Apply on effected part / whole body twice a days
  • Ternim Cream - Apply on effected part / whole body twice a days
  • Psorasun Oinment - Apply on effected part / whole body twice a days

PANCHKARMA:

  • This is an effective treatment for all types of psoriasis.
  • This special Ayurvedic treatment programme applies for 8 to 28 days

Rheumatoid Arthritis - What To Eat & What To Avoid?

MBBS, MD-Medicine, DM - Clinical Immunology
Rheumatologist, Jaipur
Rheumatoid Arthritis - What To Eat & What To Avoid?

Rheumatoid arthritis (RA) is an auto-immune disorder which induces inflammation in the joints. What causes the condition is not exactly clear, but a lot of studies have been done to establish a connection between various factors such as, diet, exercise, etc., with this condition. These studies have come up with correlation between foods and rheumatoid arthritis. There are some foods which should be a part of your diet, and some that should definitely be avoided if you have to keep the joint inflammation under control. Read on to know the top 5 foods to eat and to avoid.

What to eat?

  1. Soy: Being rich in protein and fiber and low in fat, soy is a great food for RA. It also contains omega-3 fatty acids and vegetarians especially should ensure they get enough soy in their diet.
  2. Fish: Salmon and tuna are fish that are rich in omega-3 fatty acids and these are proven to be natural anti-inflammatory agents. Therefore, it is highly recommended that people with RA eat fish about 3 to 4 times per week.
  3. Oils: While an oily diet is definitely to be avoided, some healthy oils should be included. These include sunflower oil, walnut oil, olive oil, and avocado oil. These are known for their anti-inflammatory properties and are beneficial in people with RA.
  4. Green tea: Known for their polyphenols and antioxidants, green tea reduces damage caused by inflammation in RA. People with RA are recommended to have at least 2 servings of green tea daily.
  5. Beans and legumes: The high content of fiber, protein, folic acid, zinc, iron, potassium, and other minerals makes beans a must-have for RA patients. The red and kidney variety of beans are the preferred ones.

What to avoid?

  1. Grilled foods: Grilled chicken or red meat have high levels of advanced glycation end products (AGEs) which are known to worsen inflammation. So, while they are good for weight watchers, not so if you have RA. These also contain higher levels of saturated fat, which is again not advisable for RA.
  2. Fried foods: These contain 6-omega fatty acids, which have been proven to worsen inflammation. They are also high in saturated fats, which is a strict no-no for inflammation.
  3. MSG: Monosodium glutamate which is used generously in various Oriental dishes including soups, salad dressings, etc. should be avoided as it affects liver health and worsens inflammation.
  4. Salt: Reduce overall salt intake. Limiting the intake of pickles, salad dressings and processed foods, etc., which contain high amounts of sodium.
  5. Alcohol: This again increases inflammation and should be avoided in RA.

A healthy lifestyle improves not just the overall quality of life, but also reduces the severity of symptoms of RA.

In case you have a concern or query you can always consult an expert & get answers to your questions!

4236 people found this helpful
Table of Content
About Rituximab
When is Rituximab prescribed?
What are the side effects of Rituximab ?
Key highlights of Rituximab
What are the dosage instructions?
Medicines containing Rituximab
How does medicine works?