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Regestrone 5 MG Tablet

Manufacturer :  Novartis India Ltd
Medicine Composition :  Norethisterone
Prescription vs OTC : Prescription by Doctor not required

About Regestrone 5 MG Tablet

Regestrone 5 MG Tablet is primarily used to treat amenorrhea; abnormal uterine bleeding; endometriosis, oral contraceptive; higher rate of failure with progestin-only contraceptives

Regestrone 5 MG Tablet is primarily prescribed to control excessive vaginal bleeding during menstruation. It is a synthetic form of progestin, and is effective in treating abnormal vaginal bleeding and other menstrual disorders in women which are triggered due to an imbalance of hormones.

It is also used in preventing unwanted pregnancies. It is helpful in providing contraception for about eight weeks. It mainly works by stopping the process of ovulation. It also brings changes to the lining of the uterus to make it less probable for a fertilized egg to attach to it. It comes in the form of an injection and is a convenient form of short-term contraception.

Regestrone 5 MG Tablet can produce some side effects such as acne, irregular menstrual bleeding, hirsutism, increased weight, skin reactions, feeling dizzy, nausea and voice changes. If you experience any other symptoms which you think may be due to taking this medicine, speak to your doctor for advice.

Before starting Regestrone Tablet ensure you have discussed with your doctor if you have:

  • Liver problems
  • Problem with your arteries
  • Ovarian cyst
  • Any abnormal vaginal bleeding
  • Systemic lupus erythematous
  • Porphyria
  • Breast cancer.

You will be given the injection by a healthcare professional. It is generally given during the first 1-5 days of your menstrual period. The Regestrone 5 MG Tablet is injected slowly into a muscle in your buttock. It then gradually releases into your bloodstream. The duration for this medicine to show it's effect varies from one person to another. It also depends on the intended use and levels of sex hormones in the body.

Take according to prescribed schedule. Follow instructions for regular self-breast exam. You may experience dizziness or lightheadedness; use caution when driving or engaging in tasks that require alertness until response to drug is known.

Limit intake of caffeine. Avoid high-dose vitamin C, folate, or pyridoxine. You may experience photosensitivity; use sunscreen, wear protective clothing and eyewear, and avoid direct sunlight.

Also Read: Rantac 150 MG Tablet Uses

    What are the uses of Regestrone 5 MG Tablet

    What are the contraindications of Regestrone 5 MG Tablet ?

    What are the side effects of Regestrone 5 MG Tablet ?

    Key highlights of Regestrone 5 MG Tablet

    • How long is the duration of effect?

      The duration of Regestrone 5 MG Tablet effect varies from one person to the next, based on the intent of usage. Furthermore, the dosage administered also plays a vital role in determining the effect duration.

    • What is the onset of action?

      The level of sex hormones in the body determines the time it takes for the medicine to show its intended effect. Additionally, your dosage is also an important factor for determining the onset of action.

    • Are there any pregnancy warnings?

      The medicine should not be used if you are pregnant or are planning to conceive soon. Consult your physician if you think you might be pregnant while using the medicine.

    • Is it habit forming?

      The medicine does not have any habit forming tendencies. However, you should stick to the dosage recommendation from your doctor to prevent any unforeseen complications of the medicine.

    • Are there any breast-feeding warnings?

      The medicine is not recommended to breastfeeding women, as it can harm your child. Before starting the course of the drug, you should stop breastfeeding to protect your baby from unforeseen threats from the medicine.

    • Is It safe with alcohol?

      The exact interaction of norethisterone with alcohol remains unclear. Therefore, consult your doctor to understand whether it is safe to consume alcohol along with the medication.

    • Is it safe to drive while on this medicine?

      If you experience side effects such as, drowsiness or intense headaches from the medication, you should avoid driving. However, if there are no side effects, you can safely operate heavy machinery and drive after the medicine is administered.

    • Does this affect kidney function?

      If you suffer from kidney disorders, let the doctor know. He/she will perform tests to determine whether the medication is safe for you under such circumstances.

    • Does this affect liver function?

      While the medicine does not affect liver functionality, you should report to the doctor of pre-existing liver ailments. He/she will conduct tests and determine whether Regestrone 5 MG Tablet is safe for your consumption.

    What are the substitutes for Regestrone 5 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Regestrone 5 MG Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Missed Dose instructions

      Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose then the missed dose can be skipped. It is recommended to use additional means of contraception if you have missed a scheduled dose.

    • Are there any overdose instructions?

      Contact your doctor immediately if an overdose with this medicine is suspected. Symptoms of an overdose may include nausea, vomiting, vaginal bleeding etc.

    How does this medication work?

    Regestrone 5 MG Tablet works by inhibiting the secretion of gonadotropins from the pituitary gland and preventing the maturation of follicles and the process of ovulation.

      What are the interactions of Regestrone 5 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Thyroid function test

        Report the use of this medicine if a thyroid function test is advised. This medicine may interfere with the test results.
      • Interaction with Medicine

        Decreased effect: Aminoglutethimide may decrease effects by increasing hepatic metabolism. Nelfinavir decreases norethindrone concentrations.
      • Interaction with Disease

        Use of any progestin during the first 4 months of pregnancy is not recommended. Discontinue if sudden partial or complete loss of vision, proptosis, diplopia, or migraine occur. There is a higher rate of failure with progestin only contraceptives. Progestin-induced withdrawal bleeding occurs within 3-7 days after discontinuation of drug. Use with caution in patients with asthma, diabetes, seizure disorder, migraine, cardiac or renal dysfunction, or psychic depression.
      • Interaction with Food

        Limit caffeine; high-dose vitamin C (1 g/day) may increase adverse effects; increase dietary intake of folate and pyridoxine; should be taken with food at same time each day.

      FAQs about Regestrone 5 MG Tablet

      • Ques : What is Regestrone 5 mg tablet?

        Ans : Regestrone 5 mg tablet belongs to a medicine group that contains Norethisterone as main ingredient present. It is used for the treatment of Endometrial cancer and menstrual disorders. Regestrone 5 mg tablet is prescribed to the patients having abnormal vaginal bleeding. It also controls Amenorrhea and Premenstrual syndrome. This medicine is for the patients having Breast cancer. Regestrone 5 mg tablet also treats symptoms like water retention, headache and mood swings.

      • Ques : What is the use of Regestrone 5 mg tablet?

        Ans : Regestrone 5 mg tablet is used for the treatment of conditions like Amenorrhoea and Endometrial cancer. It is also used to control abnormal uterine bleeding. Regestrone 5 mg tablet helps to improve premenstrual syndromes like headache, mood disturbances and breast pain. This medicine also prevents breast cancer. It is used as an oral contraceptive to avoid pregnancies.

      • Ques : What are the side effects of Regestrone 5 mg tablet?

        Ans : Regestrone 5 mg tablet has many common side effects such as irregular menstrual cycles, dizziness and Fainting. There are some serious side effects of this medicine like swollen facial features, Blood in cough and Migraine attacks. In case of patients, having any of the side effects or issues like blurred vision or eye bulging. It is advised to stop the consumption of Regestrone 5 mg tablet and contact to doctor as soon as possible.

      • Ques : For what treatment Regestrone 5 mg tablet used for?

        Ans : Regestrone 5 mg tablet is used for the treatment of premenstrual syndromes like headache, mood disturbances and breast pain. It is also used to control abnormal uterine bleeding. Regestrone 5 mg tablet helps to improve conditions like Amenorrhoea and Endometrial cancer. This medicine also prevents breast cancer. It is used as an oral contraceptive to avoid pregnancies.

      • Ques : How long do I need to use Regestrone 5 MG Tablet before I see improvement in my condition?

        Ans : This medication should be consumed, until the complete eradication of the disease. Thus it is advised to use, till the time directed by your doctor. Also taking this medication longer than it was prescribed, can cause an inadequate effect on the patient's condition. So please consult your doctor.

      • Ques : At what frequency do I need to use regestrone 5 mg tablet?

        Ans : The duration of effect for this medicine is dependent on the severity of the patient’s condition. Therefore the frequency of usage of this medication will vary from person to person. It is advised to follow the proper prescription of the doctor, directed according to the patient's condition.

      • Ques : Should I use regestrone 5 mg tablet empty stomach, before food or after food?

        Ans : This medication is common to be taken orally and the action of salts involved in this medication, do not depend on whether taking it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a day.

      • Ques : What are the instructions for the storage and disposal of regestrone 5 mg tablet?

        Ans : Regestrone 5 MG Tablet contains salts which are suitable to store only at room temperature, as keeping this medication above or below that, can cause an inadequate effect. Protect it from moisture and light. Keep this medication away from the reach of children. It is advised to dispose of the expired or unused medication, for avoiding its inadequate effect.

      • Ques : What is the half-life of this Regestrone 5 MG Tablet?

        Ans : 5 to 12 hours.

      • Ques : How is this Regestrone 5 MG Tablet administered?

        Ans : This medication is administered orally.


      • Norethindrone- Drug Information Portal [Internet]. 2021 [Cited 25 Nov 2021]. Available from:

      • Norethisterone 5mg Tablets- EMC [Internet]. 2017 [Cited 25 Nov 2021]. Available from:

      • Primolut N- EMC [Internet]. 2019 [Cited 25 Nov 2021]. Available from:

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician

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