Rantac 150 MG Tablet
About Rantac 150 MG Tablet
Rantac 150 MG Tablet is prescribed as the short-term treatment of active duodenal ulcers and benign gastric ulcers. This medicine is also prescribed for long-term prophylaxis of duodenal ulcer and gastric hypersecretory states, recurrent postoperative ulcer, prevention of acid-aspiration pneumonitis during surgery, and prevention of stress-induced ulcers; causes fewer interactions than cimetidine.
Rantac 150 MG belongs to a drug group known as histamine (H2) receptor blocker. Rantac 150 MG Tablet works by reducing the amount of acid produced in the stomach, effectively treating gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome and upper GI bleeding ulcers.
Patients need to be aware that intake of this medicine can increase the chances of succumbing to pneumonia. Its symptoms are pain in the chest, fever, coughing up slimy green snot and problems with breathing. Also, make sure that you are not allergic to this medication.
Make sure it is safe for you to consume this medication if you suffer from health problems like liver, kidney disease and porphyria. Although this medication does not really harm an unborn child, ensure that you tell your doctor if you are pregnant.
Rantac does pass into breast build, thus let your doctor know if you are taking this medication while breastfeeding too. It should be taken according to instructions given by the doctor. Do not change the dosage on your own.
This medication is meant for oral consumption and should be swallowed immediately. Do not chew or let the effervescent tablet dissolve after you place it in your mouth.
For instance, if you are taking 25 mg of it, dissolve it in 1 teaspoon of water. If you are taking 150 mg of this medicine, it should be dissolved in 6-8oz of water. It should be continued until the ulcer heals completely. Generally, it takes about 8 weeks for an ulcer to properly heal.
Patients who are taking certain medications should also avoid this pill. Some of these pills include metformin, Pazopanib, Dasatinib, Loperamide, Ketoconazole and Atazanavir. You can speak to your doctor about your other medications before taking this.
Take exactly as directed (at meals and bedtime); do not increase dose - may take several days before you notice relief. If antacids are approved by prescriber, allow 1 hour between antacid and Rantac 150 MG Tablet.
Avoid OTC medications, especially cold or cough medication and aspirin or anything containing aspirin. Follow the diet as the prescriber recommends.
Symptoms of overdose include muscular tremors, vomiting, rapid respiration, renal failure, CNS depression. Treatment is primarily symptomatic and supportive.
Use with caution in children <12 years of age; use with caution in patients with liver and renal impairment; dosage modification required in patients with renal impairment; long-term therapy may cause vitamin B12 deficiency.
Also Read: Ezact Mr Tablet Uses
What are the contraindications of Rantac 150 MG Tablet ?
Key highlights of Rantac 150 MG Tablet
How long is the duration of effect?
On average, the duration of the pill’s effects last for 4-5 hours. This is why doctors sometimes prescribe more than one dose per day, depending on the overall health condition of the patient who needs this medicine.
What is the onset of action?
One can notice the effects of the pill taking place an hour after it is administered orally.
Is it habit forming?
There have not been any habit forming tendencies reported amongst users of this medication.
Is It safe with alcohol?
There have been no reports regarding the interaction with alcohol.
Are there any pregnancy warnings?
Unless absolutely necessary, pregnant women should not use this medicine. It is best to consult with your doctor before doing so.
Are there any breast-feeding warnings?
Unless absolutely necessary, breastfeeding women should not use this medicine. It is best to consult with your doctor before doing so.
Is it safe to drive while on this medicine?
As some of the side effects of this pill include mental confusion and drowsiness, it is not advisable to drive after taking the pill.
Does this affect kidney function?
In case of renal impairment, doctor's consultation is a must before its administration. Dosing adjustment in renal impairment:
- Clcr 10-50 mL/minute: Administer at 75% of normal dose or administer every 18-24 hours.
- Clcr <10 mL/minute: Administer at 50% of normal dose or administer every 18-24 hours.
- Hemodialysis: Slightly dialyzable (5% to 20%).
Does this affect liver function?
Yes, it can have adverse effects on liver functions, which is why patients with liver disorders are advised not to take it.
What are the substitutes for Rantac 150 MG Tablet ?
Below is the list of medicines, which have the same composition, strength and form as Rantac 150 MG Tablet , and hence can be used as its substitute.
What are the dosage instructions?
Are there any missed dose instructions?
Rantac 150 MG Tablet is generally administered by a healthcare professional within a clinic or hospital. Thus, you may not end up missing a dose. But if you do, you can take the pill as soon as you remember it.
Are there any overdose instructions?
If you overdose on this pill, you must speak to your healthcare provider immediately.
How does this medication work?
Rantac 150 MG Tablet acts by inhibiting the action of histamine at specific H2 receptors present in the gastric parietal cells. Thus, gastric acid secretion process is inhibited.
What are the interactions of Rantac 150 MG Tablet ?
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Alcohol
Interaction with Lab Test
Interaction with Medicine
- Ketoconazole: Report the use of either of the medicine to the doctor. The use of this medication tends to make Ketoconazole less effective. Inform the doctor if the symptoms do not improve or worsen. Do not discontinue the use of any medicine without consulting your doctor.
- Loperamide: Report the use of either of the medicine to the doctor. Dose adjustment and safety monitoring may be needed when both these medicines are taken together. Your doctor may prescribe alternative medicine if your intake of Loperamide is very high or you suffer have a heart condition.
- Metformin: Report the use of either of the medicine to the doctor. An adjustment in dose and more frequent monitoring of blood level are advised when these two medicines are taken together.
- Atazanavir: Report the use of either of the medicine to the doctor. Your doctor may adjust the dosage of Atazanavir when it is to be consumed along with this medication. Do not stop the usage of any medication without consulting your doctor.
- Dasatinib: Report the usage of either of the medications to the doctor. It is advised to replace one or both of these medicines with alternates that do not interact. Do not stop the usage of any medication without consulting the doctor.
- Pazopanib: Report the use of either of the medicine to the doctor. Use of these two medications together should be avoided. Your doctor may prescribe suitable alternatives in such cases.
- Decreased toxicity of atropine.
- Increased toxicity of cyclosporine (increased serum creatinine), gentamicin (neuromuscular blockade), glipizide, glyburide, midazolam (increased concentrations), metoprolol, pentoxifylline, phenytoin, quinidine.
Interaction with Disease
- Gastrointestinal Bleeding : Use of this medication is not recommended for use if any symptoms indicating gastrointestinal bleeding exists. Consult your doctor if there is blood in vomit or the stools are bloody or black.
- Porphyria : This medication should be used with extreme caution in patients having a history of acute Porphyria.
Interaction with Food
FAQs about Rantac 150 MG Tablet
Ques : What is Rantac 150 MG Tablet?
Ans : Rantac is a medicine which contains Ranitidine as an active ingredient in it. It perform its action by lowering the amount of acid in the stomach which helps as a relief for the acids related to indigestion and heartburn. This medication is used to Duodenal Ulcer, Gastric Ulcer, gastroesophageal Reflux Disease, etc.
Ques : What is Rantac 150 mg tablet used for?
Ans : This drug is used to treat gastric ulcer, duodenal ulcer, etc.
Ques : What are the side effects of Rantac 150 mg tablet?
Ans : Side effects include sleepiness, headache, tiredness, diarrhea, etc.
Ques : Can Rantac be used to treat gastritis?
Ans : Yes, Rantac is a medicine which can be used for the treatment of gastritis. It helps by reducing the amount of acid released into the stomach and act as a reliever for stomach pain and acid reflux.
Ques : How long do I need to use Rantac 150 MG Tablet before I see improvement in my condition?
Ans : This medication should be consumed, till the complete eradication of disease. Thus it is advised to use, till the time directed by your doctor and moreover taking this medication longer than it was prescribed, can also cause inadequate effect on the patient. So please consult your doctor.
Ques : At what frequency do I need to use Rantac 150 MG Tablet?
Ans : Rantac 150 MG Tablet is generally used twice or thrice a day, as the time interval upto which this medication has an impact, is around 4 to 6 hours, but it is not the standard frequency for using this medication. It is advised to consult your doctor for the dosage, as the frequency also depends on the patient's condition.
Ques : Should I consume Rantac 150 MG Tablet empty stomach, before food or after food?
Ans : This medication is commonly taken orally from mouth and the action of salts involved in this medication, do not depend on using it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a the day.
Ques : What are the instructions for the storage and disposal of Rantac 150 MG Tablet?
Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.
Ques : How long does it take for Rantac 150 MG Tablet to start working?
Ans : This medication starts working as fast as 15 minutes from when it is given. Its effect is seen to last all day or all night.
Ques : Can I consume alcohol with Rantac 150 MG Tablet?
Ans : Alcohol does not interfere with the working of Rantac 150 MG Tablet. But, you should avoid taking alcohol as it may further damage the stomach, delaying your recovery.
Ques : Is Rantac 150 MG Tablet safe for long-term use?
Ans : There is limited data available on whether Rantac 150 MG Tablet can be used for the long term or not, but it is a relatively safe medicine. It is advised to consume Rantac 150 MG Tablet for the duration prescribed by your doctor.
Ques : Is Rantac 150 MG Tablet effective?
Ans : This drug would be effective only if used for the right indication in the dose and for the duration as advised by the doctor. It is advised to not to change the dose or stop consuming the drug without consulting your doctor.
Ranitidine- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 25 April 2019]. Available from:
Zantac Tablets 150mg- EMC [Internet]. www.medicines.org.uk. 2015 [Cited 25 April 2019]. Available from:
Ranitidine: Uses, Side effects, Dosage- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 25 April 2019]. Available from:
RANITIDINE - ranitidine hydrochloride tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2012 [Cited 25 April 2019]. Available from:
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Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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