Peploc 150 MG Tablet
Peploc 150 MG Tablet is prescribed as the short-term treatment of active duodenal ulcers and benign gastric ulcers. This medicine is also prescribed for long-term prophylaxis of duodenal ulcer and gastric hypersecretory states, recurrent postoperative ulcer, prevention of acid-aspiration pneumonitis during surgery, and prevention of stress-induced ulcers; causes fewer interactions than cimetidine.
This medicine belongs to a drug group known as histamine (H2) receptor blocker. Peploc 150 MG Tablet works by reducing the amount of acid produced in the stomach, effectively treating gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome and upper GI bleeding ulcers.
Patients need to be aware that intake of this medicine can increase the chances of succumbing to pneumonia. Its symptoms are pain in the chest, fever, coughing up slimy green snot and problems with breathing. Also, make sure that you are not allergic to this medication.
Make sure it is safe for you to consume this medication if you suffer from health problems like liver, kidney disease and porphyria. Although this medication does not really harm an unborn child, ensure that you tell your doctor if you are pregnant.
This medicine does pass into breast build, thus let your doctor know if you are taking this medication while breastfeeding too. It should be taken according to instructions given by the doctor. Do not change the dosage on your own.
This medication is meant for oral consumption and should be swallowed immediately. Do not chew or let the effervescent tablet dissolve after you place it in your mouth.
For instance, if you are taking 25 mg of it, dissolve it in 1 teaspoon of water. If you are taking 150 mg of this medicine, it should be dissolved in 6-8oz of water. It should be continued until the ulcer heals completely. Generally, it takes about 8 weeks for an ulcer to properly heal.
Take exactly as directed (at meals and bedtime); do not increase dose - may take several days before you notice relief. If antacids are approved by prescriber, allow 1 hour between antacid and Peploc 150 MG Tablet.
Avoid OTC medications, especially cold or cough medication and aspirin or anything containing aspirin. Follow the diet as the prescriber recommends.
Symptoms of overdose include muscular tremors, vomiting, rapid respiration, renal failure, CNS depression. Treatment is primarily symptomatic and supportive.
Use with caution in children <12 years of age; use with caution in patients with liver and renal impairment; dosage modification required in patients with renal impairment; long-term therapy may cause vitamin B12 deficiency.
The medication is helpful in treating the given problems:
Gastroesophageal Reflux Disease
Other Forms Of Ulcers
How long is the duration of effect?The effect of this medicine lasts for an average duration upto 8 hours.
What is the onset of action?The effect of this medicine can be observed after an hour of oral or intravenous administration.
Are there any pregnancy warnings?Caution is advised while using this medicine during pregnancy.
Is it habit forming?No habit forming tendencies were reported.
Are there any breast-feeding warnings?Caution is advised while using this medicine during pregnancy.
Does this affect liver function?Patient must consult a doctor before taking this medication in case of liver impairment.
Does this affect kidney function?In case of renal impairment, doctor's consultation is a must before its administration. Dosing adjustment in renal impairment:
- Clcr 10-50 mL/minute: Administer at 75% of normal dose or administer every 18-24 hours.
- Clcr <10 mL/minute: Administer at 50% of normal dose or administer every 18-24 hours.
- Hemodialysis: Slightly dialyzable (5% to 20%).
Is It safe with alcohol?It is suggested not to take Peploc 150 MG Tablet with alcohol, as it is unsafe to take it concomitantly.
Is it safe to drive while on this medicine?Driving is usually safe if you are taking Peploc 150 MG Tablet. As this medicine does not affect patients ability to drive.
Below is the list of medicines, which have the same composition, strength and form as Peploc 150 MG Tablet , and hence can be used as its substitute.
Missed Dose instructionsTake the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped.
Overdose instructionsContact a doctor immediately if an overdose is suspected. Symptoms of overdose may include confusion, fainting, and lightheadedness.
This medication acts by inhibiting the action of histamine at specific H2 receptors present in the gastric parietal cells. Thus, gastric acid secretion process is inhibited.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Alcohol
Interaction with Lab Test
Interaction with Medicine
KetoconazoleReport the use of either of the medicine to the doctor. The use of this medication tends to make Ketoconazole less effective. Inform the doctor if the symptoms do not improve or worsen. Do not discontinue the use of any medicine without consulting your doctor.
LoperamideReport the use of either of the medicine to the doctor. Dose adjustment and safety monitoring may be needed when both these medicines are taken together. Your doctor may prescribe alternative medicine if your intake of Loperamide is very high or you suffer have a heart condition.
MetforminReport the use of either of the medicine to the doctor. An adjustment in dose and more frequent monitoring of blood level are advised when these two medicines are taken together.
AtazanavirReport the use of either of the medicine to the doctor. Your doctor may adjust the dosage of Atazanavir when it is to be consumed along with this medication. Do not stop the usage of any medication without consulting your doctor.
DasatinibReport the usage of either of the medications to the doctor. It is advised to replace one or both of these medicines with alternates that do not interact. Do not stop the usage of any medication without consulting the doctor.
PazopanibReport the use of either of the medicine to the doctor. Use of these two medications together should be avoided. Your doctor may prescribe suitable alternatives in such cases.
Decreased toxicity of atropine.
Increased toxicity of cyclosporine (increased serum creatinine), gentamicin (neuromuscular blockade), glipizide, glyburide, midazolam (increased concentrations), metoprolol, pentoxifylline, phenytoin, quinidine.
Interaction with Diseasegastrointestinal bleeding exists. Consult your doctor if there is blood in vomit or the stools are bloody or black.
Interaction with Food
Ques: What is Peploc 150 MG Tablet?
Ques: How long do I need to use Peploc 150 MG Tablet before I see improvement in my condition?
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Ques: Should I use Peploc 150 MG Tablet empty stomach, before food or after food?
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Ques: What are the serious side effects of Peploc 150 MG Tablet?
Ques: Is Peploc 150 MG Tablet safe for long-term use?
Ques: Is Peploc 150 MG Tablet effective?
Ranitidine- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 12 December 2019]. Available from:https://druginfo.nlm.nih.gov/drugportal/rn/66357-35-5
Ranitidine- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 12 December 2019]. Available from:https://www.drugbank.ca/drugs/DB00863
Ranicalm 75mg film-coated tablets- EMC [Internet] medicines.org.uk. 2016 [Cited 12 December 2019]. Available from:https://www.medicines.org.uk/emc/product/3462/smpc
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