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Overview

Pentothal Injection

Pentothal Injection

Manufacturer: Pfizer Ltd
Medicine composition: Thiopental Sodium
Prescription vs.OTC: Prescription by Doctor required

Pentothal Injection is a depressant which is used for a wide range of purposes, from sedation to anaesthesia. It is also used to relieve pain. While primarily used as an anaesthetic for brief surgical procedures, it is also used to supplement other anaesthetics, to sedate during hypnosis, to relax the muscles in convulsive states, and also for narcosynthesis and narcoanalysis in patients with psychiatric disorders. The most common mode of administration is intravenously, though the oral and rectal modes of administration are also known. Pentothal Injection makes a person unconscious within 30-45 seconds.

The usual dosage is 3-6 mg/kg, but it may vary with age, sex, lean body mass, and certain medical conditions like burns, hypovolemia, liver failure, etc. Younger people tend to require relatively larger doses than middle-aged or elderly people, as the latter take more time to metabolize. Contraindications include absence of suitable veins for IV, porphyria, and allergy to barbiturates, Side effects of Pentothal Injection include headaches, prolonged sleepiness, nausea and agitated emergence. The hangover from the side effects can last for up to 36 hours.

Do not take Pentothal Injection unless prescribed, as it can form a habit very easily. It may also prove to be fatal in higher doses.

In addition to its intended effect, Pentothal Injection may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Is It safe with alcohol?
Thioz 500mg infusion may cause excessive drowsiness and calmness with alcohol.
Are there any pregnancy warnings?
Thioz 500mg infusion may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Are there any breast-feeding warnings?
Unknown. Human and animal studies are not available. Please consult your doctor.
Is it safe to drive while on this medicine?
Caution is advised when driving or operating machinery.
Does this affect kidney function?
There is no interaction between renal impairment and consuming this drug. So dose alteration is not needed.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Below is the list of medicines, which have the same composition, strength and form as Pentothal Injection, and hence can be used as its substitute.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Medicine
APRECAP 125MG CAPSULE
BETAONE XL 50MG TABLET
Starcad-Beta 50Mg Tablet
Supermet 50Mg Tablet Xl

Popular Questions & Answers

Is there any lab test to ascertain whether my son is a drug addict. Suppose he had constant drugs on the last three days.

M B B S, M. D (Internal Medicine)
General Physician, Nellore
Is there any lab test to ascertain whether my son is a drug addict. Suppose he had constant drugs on the last three d...
Yes there are tests. SRL RANBAXY does them. They are usually done in their central lab in Mumbai. But, please note that there is a separate test for each individual drug and each test costs around 5000. So, you have to know which drug you are testing for and there are some addictive drugs which cannot be tested. Besides this, some corporate hospitals (high end) do have those tests available.
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