Naxdom 500 Tablet

Manufacturer: Sun Pharmaceutical Industries Ltd
Medicine composition: Naproxen, Domperidone
Prescription vs OTC: Prescription by Doctor not required
Last Updated: November 09, 2022

Naxdom 500 Tablet is a combination medication, primarily prescribed for the treatment and prevention of migraine attack. This medication is comprised of two drugs, Naproxen and Domperidone, which belongs to the class of a non-steroidal anti-inflammatory drugs and dopamine antagonists, respectively.

On using this medicine some side effects like stomach upset, nausea, vomiting, heartburn, drowsiness, headache may occur. Serious side effects may include easy bruising or bleeding, painful swallowing, ringing in the ears, signs of kidney problems, mood changes, unusual tiredness, swelling of the ankles, feet and hands, unexplained stiff neck, unexplained weight gain and vision changes.

To ensure this medicine is safe for you tell your doctor if you have asthma, blood disorders, nasal polyps, liver disease, heart disease, stroke, high blood pressure or throat, stomach or intestinal problems.

Take this medicine by mouth as instructed by your doctor, usually 2 or 3 times in a day. Remember to not lie down for a minimum of 10 minutes after taking it. To prevent stomach upset, take this drug with milk, food or an antacid.

To reduce your risk of side effects, start the medication at the lowest effective dose for a short period of time. Take a higher dosage if needed, after consulting with a doctor.

Management of Naxdom 500 Tablet intoxication is primarily supportive and symptomatic; fluid therapy is commonly effective in managing the hypotension that may occur following an acute NSAID overdose, except when this is due to an acute blood loss.

Seizures tend to be very short-lived and often do not require drug treatment; although, recurrent seizures should be treated with I.V. diazepam; since many of the NSAIDs undergo enterohepatic cycling, multiple doses of charcoal may be needed to reduce the potential for delayed toxicities.

Also Read: Nicip Plus Tablet Usage

Uses of Naxdom 500 Tablet are:

  • Prevention Of Migraine Attacks

  • Nausea Or Vomiting

Side Effects of Naxdom 500 Tablet are:

  • How long is the duration of effect?

    The effects of the medication last for 6-8 hours.

  • What is the onset of action?

    Naxdom 500 Tablet has a fairly quick onset. You will begin to feel its effects within 30-60 minutes.

  • Is it habit forming?

    Habit forming tendencies have not been reported for this medicine.
  • Is It safe with alcohol?

    You should not take this drug with alcohol as it has inflammatory effects and it can nullify the effects of this medication in some people.

  • Are there any pregnancy warnings?

    Pregnant women are advised not to take this medication as it can lead to complications.

  • Are there any breast-feeding warnings?

    The amount of drug secreted in milk is too small to be harmful to the infant, and is usually found to be safe in ordinary doses. But the patient must consult before taking it.

  • Is it safe to drive while on this medicine?

    You should not drive when you have taken as it can cause drowsiness.

  • Does this affect kidney function?

    Patients with impaired kidney functions must exercise caution when taking this medication, as it can make their symptoms worse. Doctors may have to use this medicine in smaller doses.

  • Does this affect liver function?

    Patients with impaired liver function must exercise caution when taking this medication, as it can make their symptoms worse. Doctors may have to use this medicine in smaller doses.

Below is the list of medicines, which have the same composition, strength and form as Naxdom 500 Tablet , and hence can be used as its substitute.

  • Are there any missed dose instructions?

    There are no missed dose instructions. While it is advisable to take the medication at the time advised by the doctor, missing it will not cause you harm. You can take it when you remember it.

  • Are there any overdose instructions?

    In case of overdose, consult your doctor.

This NSAID drug (Non-Steroidal Anti Inflammatory Drug) that inhibit prostaglandin synthesis by non selectively impeding the COX -1 And COX -2 enzymes. It helps in alleviating inflammation, as prostaglandin is a regulator for inflammation in muscles. This also attaches to the dopaminergic receptors without causing any release of the chemical dopamine. It in turn, facilitates gastric emptying and decreases small bowel transit time.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Alcohol

    Alcohol use is strictly advised against when you are on this medicine. That is because alcohol increases the tendency of your stomach to bleed, which may be a side effect of this medicine. The bleeding is caused due to the chemical naproxen.
  • Interaction with Medicine

    It has negative interactions with antacids, amiodarone, Atazanavir, Ciprofloxacin, Clarithromycin, Bisoprolol, aluminium hydroxide and oxide, amprenavir and Aprepitant.

  • Interaction with Disease

    This medication should not be consumed in case you have had allergy to it or its active components in the past. It also should not be taken in case you have other diseases like vertigo, active peptic ulcers, kidney diseases and impairment, gastrointestinal and stomach bleeding and congestive heart failure.
  • Interaction with Food

    Food may decrease the rate but not the extent of oral absorption. Drug may cause GI upset, bleeding, ulceration, perforation; take with food or milk to minimize GI upset.

Ques: What is Naxdom 500 Tablet used for?

Ans: Naxdom 500 Tablet is a medication used to treat migraine. This medication contains domperidone and naproxen as active ingredients. Do not chew or break this medicine, it has to be swallowed as a whole and can be taken with or without food at a fixed time.

Ques: What are the side effects of Naxdom 500 Tablet?

Ans: Naxdom 500 Tablet has several side effects that can appear because of its ingredients which are domperidone and naproxen. Some of the side effects are mentioned below;
  • Drowsiness,
  • Headache,
  • Depression,
  • Itching,
  • Inability of concentration, and
  • Swelling of eyes and lips.

Ques: Is Naxdom 500 Tablet safe during pregnancy?

Ans: Kindly consult with a doctor or specialist for a recommendation on a particular case.

Ques: Is Naxdom 500 Tablet safe during Pregnancy?

Ans: Kindly consult with a doctor or specialist for a recommendation on a particular case.

Ques: How long do I need to use Naxdom 500 Tablet before I see improvement in my condition?

Ans: This medication is to be taken till the time you see an improvement in your health conditions.

Ques: At what frequency do I need to use Naxdom 500 Tablet?

Ans: This medication should be taken in the dosage as prescribed by the doctor.

Ques: What are the instructions for the storage and disposal of Naxdom 500 Tablet?

Ans: This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

Ques: What are the dietary indications while taking this Naxdom 500 Tablet?

Ans: Dietary indications should be followed as prescribed by a doctor.

Ques: How is this Naxdom 500 Tablet administered?

Ans: This medication is administered orally.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MBBS Bachelor of Medicine and Bachelor of Surgery, MBBS
General Physician
Table of Content
About Naxdom 500 Tablet
What are the uses of Naxdom 500 Tablet
What are the contraindications of Naxdom 500 Tablet ?
What are the side effects of Naxdom 500 Tablet ?
Key highlights of Naxdom 500 Tablet
What are the substitutes for Naxdom 500 Tablet ?
What are the dosage instructions?
How does this medication work?
What are the interactions of Naxdom 500 Tablet ?
FAQs about Naxdom 500 Tablet