Naxdom 500 Tablet
Naxdom 500 Tablet is a combination medication, primarily prescribed for the treatment and prevention of migraine attack. This medication is comprised of two drugs, Naproxen and Domperidone, which belongs to the class of a non-steroidal anti-inflammatory drugs and dopamine antagonists, respectively.
On using this medicine some side effects like stomach upset, nausea, vomiting, heartburn, drowsiness, headache may occur. Serious side effects may include easy bruising or bleeding, painful swallowing, ringing in the ears, signs of kidney problems, mood changes, unusual tiredness, swelling of the ankles, feet and hands, unexplained stiff neck, unexplained weight gain and vision changes.
To ensure this medicine is safe for you tell your doctor if you have asthma, blood disorders, nasal polyps, liver disease, heart disease, stroke, high blood pressure or throat, stomach or intestinal problems.
Take this medicine by mouth as instructed by your doctor, usually 2 or 3 times in a day. Remember to not lie down for a minimum of 10 minutes after taking it. To prevent stomach upset, take this drug with milk, food or an antacid.
To reduce your risk of side effects, start the medication at the lowest effective dose for a short period of time. Take a higher dosage if needed, after consulting with a doctor.
Management of Naxdom 500 Tablet intoxication is primarily supportive and symptomatic; fluid therapy is commonly effective in managing the hypotension that may occur following an acute NSAID overdose, except when this is due to an acute blood loss.
Seizures tend to be very short-lived and often do not require drug treatment; although, recurrent seizures should be treated with I.V. diazepam; since many of the NSAIDs undergo enterohepatic cycling, multiple doses of charcoal may be needed to reduce the potential for delayed toxicities.
Also Read: Nicip Plus Tablet Usage
Uses of Naxdom 500 Tablet are:
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Prevention Of Migraine Attacks
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Nausea Or Vomiting
Side Effects of Naxdom 500 Tablet are:
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Dryness In Mouth
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Flu-Like Symptoms
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How long is the duration of effect?
The effects of the medication last for 6-8 hours.
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What is the onset of action?
Naxdom 500 Tablet has a fairly quick onset. You will begin to feel its effects within 30-60 minutes.
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Is it habit forming?
Habit forming tendencies have not been reported for this medicine. -
Is It safe with alcohol?
You should not take this drug with alcohol as it has inflammatory effects and it can nullify the effects of this medication in some people.
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Are there any pregnancy warnings?
Pregnant women are advised not to take this medication as it can lead to complications.
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Are there any breast-feeding warnings?
The amount of drug secreted in milk is too small to be harmful to the infant, and is usually found to be safe in ordinary doses. But the patient must consult before taking it.
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Is it safe to drive while on this medicine?
You should not drive when you have taken as it can cause drowsiness.
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Does this affect kidney function?
Patients with impaired kidney functions must exercise caution when taking this medication, as it can make their symptoms worse. Doctors may have to use this medicine in smaller doses.
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Does this affect liver function?
Patients with impaired liver function must exercise caution when taking this medication, as it can make their symptoms worse. Doctors may have to use this medicine in smaller doses.
Below is the list of medicines, which have the same composition, strength and form as Naxdom 500 Tablet , and hence can be used as its substitute.
- Crescent Therapeutics Ltd
- Intas Pharmaceuticals Ltd
- Mission Research Laboratories Pvt Ltd
- Sterkem
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Are there any missed dose instructions?
There are no missed dose instructions. While it is advisable to take the medication at the time advised by the doctor, missing it will not cause you harm. You can take it when you remember it.
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Are there any overdose instructions?
In case of overdose, consult your doctor.
This NSAID drug (Non-Steroidal Anti Inflammatory Drug) that inhibit prostaglandin synthesis by non selectively impeding the COX -1 And COX -2 enzymes. It helps in alleviating inflammation, as prostaglandin is a regulator for inflammation in muscles. This also attaches to the dopaminergic receptors without causing any release of the chemical dopamine. It in turn, facilitates gastric emptying and decreases small bowel transit time.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
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Interaction with Alcohol
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Interaction with Medicine
It has negative interactions with antacids, amiodarone, Atazanavir, Ciprofloxacin, Clarithromycin, Bisoprolol, aluminium hydroxide and oxide, amprenavir and Aprepitant.
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Interaction with Disease
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Interaction with Food
Ques: What is Naxdom 500 Tablet used for?
Ques: What are the side effects of Naxdom 500 Tablet?
- Drowsiness,
- Headache,
- Depression,
- Itching,
- Inability of concentration, and
- Swelling of eyes and lips.
Ques: Is Naxdom 500 Tablet safe during pregnancy?
Ques: Is Naxdom 500 Tablet safe during Pregnancy?
Ques: How long do I need to use Naxdom 500 Tablet before I see improvement in my condition?
Ques: At what frequency do I need to use Naxdom 500 Tablet?
Ques: What are the instructions for the storage and disposal of Naxdom 500 Tablet?
Ques: What are the dietary indications while taking this Naxdom 500 Tablet?
Ques: How is this Naxdom 500 Tablet administered?
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Naproxen 500 mg tablets- EMC [Internet]. www.medicines.org.uk. 2018 [Cited 23 April 2019]. Available from:
https://www.medicines.org.uk/emc/product/543/smpc -
Naproxen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:
https://druginfo.nlm.nih.gov/drugportal/name/naproxen -
Domperidone 10mg Tablets- EMC [Internet]. www.medicines.org.uk. 2018 [Cited 23 April 2019]. Available from:
https://www.medicines.org.uk/emc/product/556
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