Metacin 500 MG Tablet
The active ingredient falls under the class of analgesics, belonging to the category of NSAID. This medication also reduces pain in the body caused due to fever.
You should not consume this tablet if:
- You are allergic to this medicine.
- You are suffering from a serious liver disorder.
- You normally consume more than 3 alcohol beverages per day or have a history of alcoholism.
You must not take the medicine in more than the amount prescribed or longer than the prescribed period. It can be taken with food or without it, but you must take it, in the same way, every day.
The medicine must be swallowed whole, without trying to crush, break or mixing it in water. As it is a pain reliever, it is unlikely that you will miss a dose. In case you do, refrain from taking two doses together to make up for the missed one.
There are several drugs that may interact with Metacin 500 MG Tablet. Inform your doctor about all the other medications that you take including vitamins, minerals, prescribed drugs, over the counter drugs and herbal products.
For adults Metacin 500 MG Tablet the general dose for fever and pain is 325-650 mg tablets once in every 4 to 6 hours or 1000mg tablets once in every 6 to 8 hours. It is advised to be guided by the doctor’s prescription and never to exceed the prescribed dosage.
For treating Metacin 500 MG Tablet toxicity, Acetylcysteine 140 mg/kg is administered orally (loading) followed by 70 mg/kg every 4 hours for 17 doses.
Therapy should be initiated based upon laboratory analysis suggesting high probability of hepatotoxic potential. Activated charcoal is very effective at binding acetaminophen.
Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). This medication will not reduce inflammation; consult prescriber for anti-inflammatory, if needed.
Take exactly as directed (do not increase dose or frequency); most adverse effects are related to excessive use. Take with food or milk. While using this medication, avoid alcohol and other prescription or OTC medications that contain acetaminophen or Metacin 500 MG Tablet.
How long is the duration of effect?The effect lasts for an average of 4-6 hours.
What is the onset of action?The effect of this drug can be observed within an hour of administration.
Are there any pregnancy warnings?It should be used only when necessary after consulting a doctor for pregnant women.
Is it habit forming?No habit forming tendencies were reported.
Are there any breast-feeding warnings?This medicine is not safe to use during breastfeeding. It is advised to consult your doctor before taking this medicine.
Does this affect liver function?Appears to be well tolerated in cirrhosis; serum levels may need monitoring with long-term use.
Does this affect kidney function?Dose adjustment is needed in case of renal impairment. Dosing interval in renal impairment:
- Clcr 10-50 mL/minute: Administer every 6 hours.
- Clcr <10 mL/minute: Administer every 8 hours (metabolites accumulate)
- Hemodialysis: Moderately dialyzable (20% to 50%).
Is It safe with alcohol?Excessive intake of alcohol may increase the risk of acetaminophen-induced hepatotoxicity; avoid or limit alcohol intake.
Below is the list of medicines, which have the same composition, strength and form as Metacin 500 MG Tablet , and hence can be used as its substitute.
Are there any missed dose instructions?The missed dose should be taken as soon as possible.
Are there any overdose instructions?An overdosage could cause harmful effects on the body.
The drug is a pain relief medication that selectively inhibits enzyme function in the brain which allows it to treat pain and fever. It activates certain receptors in the brain that inhibit pain signals.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Alcohol
Interaction with Lab Test
5-HIAA Urine TestYou may get a false-positive result for this test if you take Metacin 500 MG Tablet.
Interaction with Medicine
Interaction with Food
Interaction with Disease
Ques: What is Metacin 500 MG Tablet?
Ques: What are the uses of Metacin 500 MG Tablet?
Ques: What are the Side Effects of Metacin 500 MG Tablet?
Ques: What are the instructions for storage and disposal Metacin 500 MG Tablet?
Ques: Should I use Metacin 500 MG Tablet empty stomach, before food or after food?
Ques: How long do I need to use Metacin 500 MG Tablet before I see improvement of my conditions?
Ques: Is there any food or drink I need to avoid?
Ques: Will Metacin 500 MG Tablet be more effective if taken in more than the recommended dose?
Ques: Can I take other medications along with Metacin 500 MG Tablet?
Ques: Can I take Metacin 500 MG Tablet with antibiotics?
Ques: Is Metacin 500 MG Tablet an NSAID drug?
Dolo 650 mg (Paracetamol): Uses, Side Effects, Dosage- Drugs Bank [Internet]. drugsbanks.com. 2018 [Cited 3 December 2021]. Available from:https://www.drugsbanks.com/dolo-650-mg/
Acetaminophen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 3 December 2021]. Available from:https://druginfo.nlm.nih.gov/drugportal/name/paracetamol
Anadin Paracetamol Tablets- EMC [Internet]. www.medicines.org.uk. 2016 [Cited 3 December 2021]. Available from:https://www.medicines.org.uk/emc/product/11899/smpc
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