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Overview

Macpred 4 MG Tablet

Manufacturer :  Macleods Pharmaceuticals Pvt.Ltd
Medicine Composition :  Methyl Prednisolone
Prescription vs OTC : Prescription by Doctor required

About Macpred 4 MG Tablet

Macpred 4 MG Tablet is primarily as an anti-inflammatory or immunosuppressant agent in the treatment of a variety of diseases including those of hematologic, allergic, inflammatory, neoplastic, and autoimmune origin. It is also used in the prevention and treatment of graft-versus-host disease following allogeneic bone marrow transplantation.

Macpred 4 MG Tablet is a steroid, which prevents the release of certain chemicals in the body that result in inflammation. The drug is quite effective in the treatment of a number of inflammatory health problems such as gland disorders, lupus, arthritis, psoriasis as well as ulcerative colitis.

It also treats various other inflammatory conditions of the lungs, skin, eyes, blood cells, stomach and nervous system of the body. Before you start the medicine the doctor needs to ensure:

  • If the medicine is safe for the patient
  • If you have allergies, overall fitness, and existing health problems
  • If you have problems like hypertension, heart disease, kidney or liver issues, tuberculosis, pinworms, thyroid disorders, mental illness, epilepsy or epilepsy

The dosage of the medicine for adults may vary from 4mg to 48mg daily. In the case of children, the dosage is decided to depend upon the health of the patient and the condition that is being treated.

Certain precautions should also be taken to prevent side effects from aggravating. For instance, avoid grapefruit juice consumption. it is also advised that ‘live’ vaccines should not be taken when on this drug. Patients taking this medication can easily catch infections. Thus they should also avoid interacting with sick family members or friends.

Macpred 4 MG Tablet must be used with caution in patients with hyperthyroidism, cirrhosis, nonspecific ulcerative colitis, hypertension, osteoporosis, thromboembolic tendencies, CHF, convulsive disorders, myasthenia gravis, thrombophlebitis, peptic ulcer, diabetes.

Because of the risk of adverse effects of Macpred 4 MG Tablet, systemic corticosteroids should be used cautiously in the elderly, in the smallest possible dose, and for the shortest possible time.

Arrhythmias and cardiovascular collapse are possible with rapid intravenous infusion of high dose methylprednisolone. Symptoms of overdose include cushingoid appearance (systemic), muscle weakness (systemic), osteoporosis (systemic) all with long-term use only.

When consumed in excessive quantities for prolonged periods, systemic hypercorticism and adrenal suppression may occur; in those cases, discontinuation and withdrawal of the corticosteroid should be done judiciously.

Maintain adequate nutritional intake; consult prescriber for possibility of special dietary instructions. If diabetic, monitor serum glucose closely and notify prescriber of any changes; this medication can alter hypoglycemic requirements.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the uses of Macpred 4 MG Tablet

    • Immunosuppression

    • Asthma

    • Eye Disorder

    • Skin Disorders

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the contraindications of Macpred 4 MG Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the side effects of Macpred 4 MG Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Key highlights of Macpred 4 MG Tablet

    • How long is the duration of effect?

      The effect of this medicine lasts for a duration of 30-36 hours after an oral dose and 1-4 weeks after an intramuscular injection.

    • What is the onset of action?

      The peak effect of this medicine is observed within 30 minutes of an intravenous injection.

    • Are there any pregnancy warnings?

      This medicine is recommended for pregnant women only if clearly needed and if no other safer alternative is available.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      This medicine is known to be excreted through breast milk in small amounts.

    • Is It safe with alcohol?

      Consumption of alcohol must be avoided when you were taking Macpred 4 MG Tablet.

    • Is it safe to drive while on this medicine?

      This medicine might affect the consciousness of the patient, thus driving must be avoided.

    • Does this affect kidney function?

      This medicine is found to be safe in patient with kidney disease. Adjustment of dose is not needed.

    • Does this affect liver function?

      Limited information is available on the use of this medicine in patient with liver disease. kindly consult your doctor before taking this.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the substitutes for Macpred 4 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Macpred 4 MG Tablet , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for your next dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Where is the Macpred 4 MG Tablet approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    How does this medication work?

    This medicine belongs to Glucocorticoids class of drugs. It works by binding to the receptor and inhibits the release of inflammatory substances thus helps in the treatment of inflammation or allergic disorders.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

      What are the interactions of Macpred 4 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Macpred 4 MG Tablet interferes with skin tests.
      • Interaction with Medicine

        • CYP3A enzyme inducer.
        • Phenytoin, phenobarbital, rifampin increase clearance of methylprednisolone.
        • Potassium depleting diuretics enhance potassium depletion.
        • Increased toxicity:
          • Skin test antigens, immunizations decrease response and increase potential infections
          • Methylprednisolone may increase circulating glucose levels and may need adjustments of insulin or oral hypoglycemics
      • Interaction with Disease

        Gastrointestinal Bleeding

        This medication is used with caution in patients with gastrointestinal diseases. The risk of bleeding is more when taken for a long duration of time. Dose adjustments are to be made based on the clinical condition.

        Diabetes

        This medicine is used with caution in the patients with diabetes as it increases the blood glucose levels. Regular monitoring of blood glucose levels is necessary. A suitable antidiabetic agent is prescribed based on the clinical condition.

        Others

        Use with caution in patients with hyperthyroidism, cirrhosis, nonspecific ulcerative colitis, hypertension, osteoporosis, thromboembolic tendencies, CHF, convulsive disorders, myasthenia gravis, thrombophlebitis, peptic ulcer.
      • Interaction with Food

        • Consumption of grapefruit juice is not recommended when you are taking Macpred 4 MG Tablet. Inform the doctor if you experience any undesired effects.
        • Should be taken after meals or with food or milk; limit caffeine; need a diet rich in pyridoxine, vitamin C, vitamin D, folate, calcium, phosphorus, and protein.

        FAQs about Macpred 4 MG Tablet

        • Ques : What is Macpred 4 MG Tablet?

          Ans : This medication is a steroid, which prevents the release of certain chemicals in the body that result in inflammation.

        • Ques : How long do I need to use Macpred 4 MG Tablet before I see improvement in my condition?

          Ans : It is advisable to take this drug for the duration prescribed by your doctor. Do not stop the treatment suddenly or take for a longer period than recommended by your doctor.

        • Ques : At what frequency do I need to use Macpred 4 MG Tablet?

          Ans : This medication should be taken in the dosage as prescribed by the doctor.

        • Ques : Should I use Macpred 4 MG Tablet empty stomach, before food or after food?

          Ans : This medication should be taken after food in a prescribed dosage.

        • Ques : What are the instructions for the storage and disposal of Macpred 4 MG Tablet?

          Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

        • Ques : Does Macpred 4 MG Tablet contain penicillin?

          Ans : No, it does not contain penicillin. This drug belongs to a group of medicines called steroids.

        • Ques : Does Macpred 4 MG Tablet expire?

          Ans : Yes, it does expire. All the medicines come with an expiry date mentioned on the pack. It is advised for you to check the expiry date mentioned on the medicine before use.

        • Ques : Is Macpred 4 MG Tablet a pain-killer?

          Ans : No, Macpred 4 MG Tablet is not a pain-killer.

        • Ques : Is Macpred 4 MG Tablet safe?

          Ans : This drug is completely safe to use if taken as per the prescription of the doctor.

        • Ques : Is Macpred 4 MG Tablet an immunosuppressant?

          Ans : This drug has immunosuppressant properties which means it suppresses the body’s immune system. Hence, it is used for the treatment of a number of inflammatory and auto-immune conditions.

        • Ques : Is Macpred 4 MG Tablet a glucocorticoid?

          Ans : Yes, it is a glucocorticoid. It belongs to a group of medicines called steroids (corticosteroids).

        • Ques : Can I take Macpred 4 MG Tabletn with antibiotics?

          Ans : Certain antibiotics may increase the metabolism of this medication and hence decrease its effects.

        • Ques : Can I take Macpred 4 MG Tablet with paracetamol?

          Ans : Yes, this drug can be taken with paracetamol.

        References

        • Methylprednisolone-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 1 June 2022].Available from:

          https://druginfo.nlm.nih.gov/drugportal/name/methylprednisolone

        • Methylprednisolone-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 1 June 2022].Available from:

          https://go.drugbank.com/drugs/DB00959

        • METHYLPREDNISOLONE Tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 1 June 2022].Available from:

          https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=METHYLPREDNISOLONE

        Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

        Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

        Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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        Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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        Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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