Estrogen is a female sex hormone responsible for the regulation and development of the female reproductive system. It is used in the treatment of postmenopausal osteoporosis, female hypogonadism, etc.
The use of this drug is associated with increased risk of blood clotting, cardiovascular disease, stroke, uterine cancer or breast cancer. Before using this medication you should notify your doctor if you have or are:
- Pregnant or plan on becoming pregnant
A condition or history of-
- Liver disease
- Blood clotting
- Heart attack
- Allergic to any medicines.
It can be taken orally, vaginally, topically, or via injection. It should be taken only as per the prescribed dosage is given by the doctor according to your conditions.
Symptoms of overdose include fluid retention, jaundice, thrombophlebitis.Toxicity is unlikely following single exposures of excessive doses, any treatment should be supportive and symptomatic.
This drug can only be given I.M. It is important to maintain schedule of drug days and drug-free days. Periodic gynecologic exam and breast exams are important.
Report significant swelling of extremities, sudden acute pain in legs or calves, chest, or abdomen; shortness of breath; severe headache or vomiting; weakness or numbness of arms or legs; or unusual vaginal bleeding.
The drug is utilised to fix the accompanying ailments
Post Menopausal Osteoporosis
Primary Ovarian Failure
Is It safe with alcohol?Interaction with alcohol is unknown. Please consult your doctor.
Are there any pregnancy warnings?Inform prescriber if you are pregnant. Do not get pregnant during or for 1 month following therapy. Consult prescriber for instruction on appropriate barrier contraceptive measures. This drug may cause severe fetal defects.
Are there any breast-feeding warnings?The drug is suggested to be ignored by breastfeeding mothers as there is a possibility of side-effects on infant. You should consult your doctor to evaluate the potential benefits and risks before taking the medicine.
Is it safe to drive while on this medicine?There is no data available. Please consult doctor before consuming the drug.
Does this affect kidney function?There is no data available. Please consult doctor before consuming the drug.
Does this affect liver function?Dosing adjustment of Estrogen in hepatic impairment:
- Mild to moderate liver impairment: Dosage reduction of estrogens is recommended.
- Severe liver impairment: Not recommended.
Are there any overdose instructions?Seek emergency medical treatment or contact the doctor in case of an overdose.
Are there any missed dose instructions?If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
This medication primarily functions as a regulator of the transcription rate for certain genes present in the uterus. This medication plays an active role as the sex hormone in the female body.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Lab Test
- Decreased antithrombin III
- Decreased serum folate concentration
- Increased prothrombin and factors VII, VIII, IX, X
- Increased platelet aggregability
- Increased thyroid binding globulin
- Increased total thyroid hormone (T4)
- Increased serum triglycerides/phospholipids
Interaction with Medicine
- Decreased effect: Rifampin decreases estrogen serum concentrations.
- Hydrocortisone increases corticosteroid toxic potential.
- Anticoagulants: Increases potential for thromboembolic events with anticoagulants.
- Carbamazepine, tricyclic antidepressants, and corticosteroids; increased thromboembolic potential with oral anticoagulants.
Interaction with Disease
Ques: What is Estrogen?
Ques: How long do I need to use Estrogen before I see improvement in my condition?
Ques: At what frequency do I need to use Estrogen?
Ques: Should I use Estrogen empty stomach, before food or after food?
Ques: What are the instructions for the storage and disposal of Estrogen?
Estrogens- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2021 [Cited 3 December 2021]. Available from:https://druginfo.nlm.nih.gov/drugportal/sid/d004967000
ESTROGEN- folliculinum, oophorinum liquid- Daily Med [Internet]. dailymed.nlm.nih.gov. 2018 [Cited 24 Nov 2021]. Available from:https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0c72f252-433f-4a8f-968e-6a511cddafc9
ESTROGEN PHENOLIC- estradiol, liquid- EMC [Internet]. www.medicines.org.uk. 2021 [Cited 24 Nov 2021]. Available from:https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=716cd86c-af47-45a6-b710-fed421e78fb5
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